基本信息:
- 专利标题： 新型含吡啶基冠醚的手性双磷配体及其在不对称催化反应中的应用
- 专利标题（英）：Novel pyridyl crown ether-containing chiral diphosphine ligand and application thereof in asymmetric catalytic reaction
- 申请号：CN201610100247.X 申请日：2016-02-24
- 公开(公告)号：CN105585593A 公开(公告)日：2016-05-18
- 发明人： 吴静 , 章喜昌 , 李世军
- 申请人： 杭州师范大学
- 申请人地址： 浙江省杭州市余杭区仓前街道海曙路58号
- 专利权人： 杭州师范大学
- 当前专利权人： 杭州师范大学
- 当前专利权人地址： 浙江省杭州市余杭区仓前街道海曙路58号
- 代理机构： 杭州君度专利代理事务所
- 代理人： 杜军
- 主分类号： C07F9/6561
- IPC分类号： C07F9/6561 ; C07F15/00 ; C07F19/00 ; C07D498/08 ; B01J31/24 ; C07B53/00 ; C07C233/47 ; C07C231/12 ; C07D307/54 ; C07D333/24 ; C07D215/06
The invention discloses a novel pyridyl crown ether-containing chiral diphosphine ligand and an application thereof in an asymmetric catalytic reaction. The structural formulas of the chiral diphosphine ligand and an intermediate thereof, namely a pyridyl crown ether-containing monophosphorous ligand are shown by (I) and (I') respectively. The transition metal compounds of the chiral diphosphine ligands can serve as a catalyst of an asymmetric reaction; the pyridyl crown ether-containing chiral diphosphine ligand is a kind of novel adjustable chiral ligand; and through the complexing of different objects such as alkali metal ions, alkaline-earth metal ions, rare-earth metal ions, ammonium salt and organic amine salt with a ligand, the control on the space structure and electronic properties of the catalyst can be realized. The transition metal (Rh and Ir) complex of the pyridyl crown ether-containing chiral diphosphine ligand in complexing assembly with alkali metal ions shows excellent catalytic activity and good stereoselectivity.
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07F | 含除碳、氢、卤素、氧、氮、硫、硒或碲以外的其他元素的无环，碳环或杂环化合物 |
| ------C07F9/00 | 含周期表第Ⅴ族元素的化合物 |
| --------C07F9/02 | .磷化合物 |
| ----------C07F9/06 | ..无P—C键的 |
| ------------C07F9/6561 | ...含有稠合杂环系 |