The invention discloses a handmade embroidery insole with the sterilization and deodorization function. The handmade embroidery insole with the sterilization and deodorization function comprises an insole body and an embroidery pattern layer embroidered on the insole body; the embroidery pattern layer is composed of a water-absorbing layer, an antibacterial layer and an embroidery pattern; the antibacterial layer is connected to the upper plane of the water-absorbing layer through an adhesive layer; the embroidery pattern is composed of rhombic protrusion structures different in size, and deodorization materials are arranged in rhombic protrusions. The total area of the embroidery pattern accounts for 2/3 of the area of the insole body. In this way, the handmade embroidery insole with the sterilization and deodorization function has the functions of being soft, breathable, resistant to wear and capable of absorbing sweat, removing odor and killing bacteria, and has both traditional charm and a modern style.