The invention discloses a method for synthesizing a thiazole methylamino pyridine compound 6-methoxy-N-((2-chlorothiazol-5-yl)methyl)-N-ethyl-3-nitropyridin-2-amine. According to the method, 2-chloro-5-ethylaminemethylthiazol and 2-chloro-6-methoxy-3-nitropyridine are used as raw materials; toluene is adopted as a solvent; a sodium hydroxide water solution is used as an acid-binding agent; and the synthesis is carried out under the effect of a catalyst tetrabutyl ammonium bromide, or benzyltrimethyl ammonium chloride, or benzyltriethyl ammonium chloride, or tetraethyl ammonium bromide, or tetrabutyl ammonium iodide. A chemical reaction formula is shown below. According to the invention, the acid-binding agent and the reaction solvent are changed, and the catalyst is added, such that reaction is full and complete, reaction speed is greatly improved, reaction time is shortened, reaction yield is improved, and product purity is improved. The process is simple to operate. Post-treatments of the novel solvent toluene and the acid-binding agent sodium hydroxide water solution are simple, and the solvent and the acid-binding agent are easy to recycle. With the method, three-waste amount is low, production cost is reduced, and industrialized application value is high.