The invention relates to a high-voltage power grid telescopic guide connection device comprising a shell and a sliding guide rail. The inlet of the sliding guide rail is machined in one side of the shell, and the outlet of the sliding guide rail is machined in the other side of the shell. The sliding guide rail slides in a parallel way and is mounted in the shell in a penetrating way. One end of the sliding guide rail extends to the outer side of the shell and is mounted on a door body near the position a high-voltage power grid connecting line, and the other end of the sliding guide rail is disposed inside the shell and is equipped with a guide ring. A fixing steel cable is mounted inside the shell, and the guide ring is mounted on the fixing steel cable in a penetrating way. A plurality of sliding rings are mounted on the fixing steel cable in a penetrating way. A high-voltage line sequentially passes through the sliding guide rail, the guide ring and the sliding rings and is led out from a high-voltage line outlet of the shell. The high-voltage power grid telescopic guide connection device of the invention is simple in structure and convenient to mount and use. By adopting the device, damage to the high-voltage line can be avoided, the service life of the high-voltage line can be prolonged, normal operation of the circuit is ensured, the safety of high-voltage line connection is ensured, and the potential safety risks in work are eliminated.