A heat-dissipation device comprises a heat-dissipation base, a plurality of fins fixed on the heat-dissipation base, and a plurality of fixing pieces arranged on the heat-dissipation base in a penetrating manner, wherein the heat-dissipation base comprises a bottom plate, a top plate and a plurality of heat pipes interlaid between the top plate and the bottom plate; the heat-dissipation base also comprises a frame body interlaid between the bottom plate and the top plate and surrounding the heat pipes; the frame body comprises a plurality of frame strips that are in end-to-end connection with each other sequentially; a containing space is defined by the frame strips, the bottom plate and the top plate to contain the heat pipes; each of the fixing pieces penetrates through the bottom plate, the frame strips of the frame body and the top plate. As the frame body is connected with the peripheries of the bottom plate and the top plate, the heat-dissipation device avoids the deformation of the bottom plate and the top plate due to the fact that the bottom plate and the top plate are relatively thin and have a difficulty in bearing lock forces of the fixing pieces, the strength of the heat-dissipation device is effectively improved, and the heat pipes are well protected.