基本信息:
- 专利标题： 用于治疗与心血管、代谢和炎性疾病领域相关的疾病的多不饱和脂肪酸
- 专利标题（英）：Polyunsaturated fatty acids for the treatment of diseases related to cardiovascular, metabolic and inflammatory disease areas
- 申请号：CN201080030436.5 申请日：2010-05-07
- 公开(公告)号：CN102459142A 公开(公告)日：2012-05-16
- 发明人： R.霍夫兰 , A.K.霍尔迈德 , T.斯克杰雷特 , M.布伦德范格
- 申请人： 普罗诺瓦生物医药挪威公司
- 申请人地址： 挪威利萨克
- 专利权人： 普罗诺瓦生物医药挪威公司
- 当前专利权人： 普罗诺瓦生物医药挪威公司
- 当前专利权人地址： 挪威利萨克
- 代理机构： 北京市柳沈律师事务所
- 代理人： 刘国军
- 优先权： 61/176,503 2009.05.08 US
- 国际申请： PCT/IB2010/001251 2010.05.07
- 国际公布： WO2010/128401 EN 2010.11.11
- 进入国家日期： 2012-01-06
- 主分类号： C07C57/03
- IPC分类号： C07C57/03 ; A61K31/19 ; A61K31/22 ; A61P19/02 ; A61P29/00 ; A61P3/10 ; A61P9/10 ; C07C69/587
The present disclosure relates to lipid compounds of the general formula (I): R1-O-C(R2)(R3) -X (I) wherein R1 is a C10-C22 alkyl group, a C10-C22 alkenyl group having 1-6 double bonds, or a C10-C22 alkynyl group having 1-6 triple bonds; R2 and R3 are the same or different and may be chosen from different substituents; and X is a carboxylic acid or a derivative thereof, such as a carboxylic ester, a carboxylic anhydride, a phospholipid, triglyceride, or a carboxamide; or a pharmaceutically acceptable salt, solvate, solvate of such salt or a prodrug thereof.The present disclosure also relates to pharmaceutical compositions and lipid compositions comprising at least one compound according to the present disclosure, and to such compounds for use as medicaments or for use in therapy, in particular for the treatment of diseases related to the cardiovascular, metabolic, and inflammatory disease area.
公开/授权文献:
- CN102459142B 用于治疗与心血管、代谢和炎性疾病领域相关的疾病的多不饱和脂肪酸 公开/授权日：2017-08-08