基本信息:
- 专利标题： 用于肿瘤特征和标记物组鉴定,肿瘤分级的方法和用于癌的标记物组
- 专利标题（英）：Process for tumour characteristic and marker set identification, tumour classification and marker sets for cancer
- 申请号：CN201080020971.2 申请日：2010-04-16
- 公开(公告)号：CN102421920A 公开(公告)日：2012-04-18
- 发明人： E·王 , 李杰 , 邓迎海 , A·EG·伦费林克 , M·D·奥康纳-麦考特 , E·普里西马
- 申请人： 加拿大国家研究委员会
- 申请人地址： 加拿大安大略
- 专利权人： 加拿大国家研究委员会
- 当前专利权人： 加拿大国家研究委员会
- 当前专利权人地址： 加拿大安大略
- 代理机构： 中国国际贸易促进委员会专利商标事务所
- 代理人： 罗菊华
- 优先权： 61/202,881 2009.04.16 US
- 国际申请： PCT/CA2010/000565 2010.04.16
- 国际公布： WO2010/118520 EN 2010.10.21
- 进入国家日期： 2011-11-11
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12N15/11
A process to identify tumour characteristics involves obtaining three different marker sets each predictive of a characteristic of interest, obtaining a sample gene expression signals from tumour cells, adding a reporter to affect a change in the sample permitting assessment of a gene expression signal of interest in the tumour, combining the gene expression signals with the reporter, correlating the extracted gene expression signals to the three different marker sets, assigning a designation to the extracted gene expression signals according to the following rankings: if the correlation of all three predictive gene expression signal sets predict it to have characteristics of concern, it is designated a bad tumour; if the correlation of all three predictive gene expression signal sets predict it to lack characteristics of concern it is designated a good tumour; and, if the correlation of all three predictive gene expression signal sets do not provide the same predicted clinical outcome, the tumour is designated as ''intermediate''; and, outputting said designation.
公开/授权文献:
- CN102421920B 用于肿瘤特征和标记物组鉴定,肿瘤分级的方法和用于癌的标记物组 公开/授权日：2015-09-30