基本信息:
- 专利标题： 一种二乙酸碘苯的制备方法
- 专利标题（英）：Method for preparing iodobenzene diacetate
- 申请号：CN200910049332.8 申请日：2009-04-15
- 公开(公告)号：CN101575293A 公开(公告)日：2009-11-11
- 发明人： 俞建新 , 顾建良 , 费巧龙 , 张林宝
- 申请人： 上海予利化学科技有限公司
- 申请人地址： 上海市金山区秋实路688号4号楼208室
- 专利权人： 上海予利化学科技有限公司
- 当前专利权人： 上海予利生物科技股份有限公司
- 当前专利权人地址： 上海市金山区秋实路688号4号楼208室
- 代理机构： 上海科盛知识产权代理有限公司
- 代理人： 赵志远
- 主分类号： C07C71/00
- IPC分类号： C07C71/00
The invention relates to a method for preparing iodobenzene diacetate, which comprises the following steps: using tetrahydrate sodium perborate as a raw material to perform acylation reaction with iodobenzene in the presence of a glacial acetic acid/acetic anhydride mixed solution, wherein the molar ratio of the tetrahydrate sodium perborate to the iodobenzene is 3-10:1, the reaction temperature is between 30 and 45 DEG C, and the reaction time is between 4 and 24 hours; after the reaction, adding ice water to obtain a crude product of the iodobenzene diacetate; and performing recrystallization to obtain the iodobenzene diacetate. Compared with the prior art, the method has the advantages of reasonable process, simple operation and safe production, is suitable for industrial mass production, and provides a favorable condition for producing the iodobenzene diacetate industrially.
公开/授权文献:
- CN101575293B 一种二乙酸碘苯的制备方法 公开/授权日：2012-11-28