基本信息:
- 专利标题： Expanding the eukaryotic genetic code
- 申请号：AU2004233083 申请日：2004-04-16
- 公开(公告)号：AU2004233083B2 公开(公告)日：2010-09-16
- 发明人： SCHULTZ PETER G , CROPP ASHTON T , ANDERSON CHRISTOPHER J , CHIN JASON W
- 申请人： SCRIPPS RESEARCH INST
- 专利权人： SCRIPPS RESEARCH INST
- 当前专利权人： SCRIPPS RESEARCH INST
- 优先权： US47993103 2003-06-18; US49654803 2003-08-19; US49301403 2003-08-05; US46386903 2003-04-17
- 主分类号： C12N9/10
- IPC分类号： C12N9/10 ; C07H21/04 ; C12N20060101 ; C12N9/16 ; C12N9/22 ; C12N15/00 ; C12N15/10 ; C12N15/12 ; C12N15/54 ; C12P21/00 ; C12P21/06 ; C12Q1/68
摘要：
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.
公开/授权文献:
- AU2004233083A1 Expanding the eukaryotic genetic code 公开/授权日：2004-11-04