基本信息:
- 专利标题: Expanding the eukaryotic genetic code
- 申请号:AU2004233083 申请日:2004-04-16
- 公开(公告)号:AU2004233083A1 公开(公告)日:2004-11-04
- 发明人: SCHULTZ PETER G , CROPP ASHTON T , ANDERSON CHRISTOPHER J , CHIN JASON W
- 申请人: SCRIPPS RESEARCH INST
- 专利权人: SCRIPPS RESEARCH INST
- 当前专利权人: SCRIPPS RESEARCH INST
- 优先权: US47993103 2003-06-18; US49654803 2003-08-19; US49301403 2003-08-05; US46386903 2003-04-17
- 主分类号: C07H21/04
- IPC分类号: C07H21/04 ; C12N20060101 ; C12N9/16 ; C12N9/22 ; C12N15/00 ; C12N15/10 ; C12P21/06 ; C12Q1/68
摘要:
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.
公开/授权文献:
- AU2004233083B2 Expanding the eukaryotic genetic code 公开/授权日:2010-09-16
信息查询:
EspacenetIPC结构图谱:
C | 化学;冶金 |
--C07 | 有机化学 |
----C07H | 糖类;及其衍生物;核苷;核苷酸;核酸 |
------C07H21/00 | 含有两个或多个单核苷酸单元的化合物,具有以核苷基的糖化物基团连接的单独的磷酸酯基或多磷酸酯基,例如核酸 |
--------C07H21/04 | .以脱氧核糖基作为糖化物基团 |