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1. 外观设计

USD906738S1 Mattress 有权
公开(公告)号：USD906738S1
公开(公告)日：2021-01-05
申请号：US29747096
申请日：2020-08-19
申请人： Li Yang
设计人： Li Yang

2. 发明授权

US09283541B2 Thin layer chromatography plates and related methods 有权
标题翻译：薄层色谱板及相关方法
公开(公告)号：US09283541B2
公开(公告)日：2016-03-15
申请号：US13035645
申请日：2011-02-25
申请人： Matthew R. Linford , Robert C. Davis , Richard R. Vanfleet , David Scott Jensen , Li Yang , Jun Song
发明人： Matthew R. Linford , Robert C. Davis , Richard R. Vanfleet , David Scott Jensen , Li Yang , Jun Song
IPC分类号： B01J20/28 , B01J20/282 , B01J20/286 , B82Y30/00 , B82Y40/00 , G01N30/92 , G01N30/93
CPC分类号： B01J20/282 , B01J20/28007 , B01J20/286 , B82Y30/00 , B82Y40/00 , G01N30/92 , G01N30/93
摘要： In an embodiment, a method for manufacturing a thin layer chromatography (“TLC”) plate is disclosed. The method includes forming a layer of elongated nanostructures (e.g., carbon nanotubes), and at least partially coating the elongated nanostructures with a coating. The coating includes a stationary phase and/or precursor of a stationary phase for use in chromatography. The stationary phase may be functionalized with hydroxyl groups by exposure to acidified water vapor or immersion in a concentrated acid bath (e.g., HCl and methanol). At least a portion of the elongated nanostructures may be removed after being coated. Embodiments for TLC plates and related methods are also disclosed.
摘要翻译：在一个实施方案中，公开了薄层色谱（“TLC”）板的制造方法。该方法包括形成细长的纳米结构层（例如，碳纳米管），并且用涂层至少部分地涂覆细长的纳米结构。涂层包括用于色谱法的固定相和/或固定相的前体。固定相可以通过暴露于酸化水蒸气或浸入浓酸浴（例如HCl和甲醇）中的羟基官能化。至少一部分细长的纳米结构可以在被涂覆之后被去除。还公开了TLC板的实施例和相关方法。

3. 发明申请

US20150335670A1 Medical applications of Notoginsenoside Fc 审中-公开
标题翻译：三七皂苷Fc的医学应用
公开(公告)号：US20150335670A1
公开(公告)日：2015-11-26
申请号：US14760149
申请日：2014-01-09
申请人： Zhengtao WANG , Bo GAO , Li YANG , Xiaojun WU , Wei DOU , Chun Yong HE , Qing LIU , Rufeng WANG , Eryun ZHANG , SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
发明人： Zhengtao Wang , Bo Gao , Li Yang , Xiaojun Wu , Wei Dou , Chunyong He , Qing Liu , Rufeng Wang , Eryun Zhang
IPC分类号： A61K31/704 , A23L1/30
CPC分类号： A61K31/704 , A23L33/10 , A23V2002/00
摘要： A method for preparing a platelet aggregation inhibitor, a blood coagulation inhibitor, and a pharmaceutical composition or a food for preventing or treating thrombotic diseases, includes applying notoginsenoside Fc.
摘要翻译：制备血小板聚集抑制剂，凝血抑制剂和用于预防或治疗血栓形成疾病的药物组合物或食品的方法包括施用三七皂苷Fc。

4. 发明授权

US08809499B2 Fusion protein of human fibroblast growth factor-21 and exendin-4 有权
标题翻译：人成纤维细胞生长因子-21和毒蜥外泌肽-4的融合蛋白
公开(公告)号：US08809499B2
公开(公告)日：2014-08-19
申请号：US13391226
申请日：2010-03-12
申请人： Kai Fan , Zhiquan Zhao , Chun Zhang , Yong Chen , Hua Luo , Li Yang , Honghong Liu
发明人： Kai Fan , Zhiquan Zhao , Chun Zhang , Yong Chen , Hua Luo , Li Yang , Honghong Liu
IPC分类号： C07K14/50 , C12N1/21 , C12N15/12 , C12N15/63 , C07K14/605 , C07K14/43 , A61K38/00
CPC分类号： C07K14/43 , A61K38/00 , C07K14/50 , C07K14/605 , C07K2319/00
摘要： Provided is a fusion protein, which comprises human fibroblast growth factor 21 and glucagon-like-peptide-1 or its analogs. Also provided is the medicament composition comprising the fusion protein, which can be used for treating or preventing obesity, diabetes, hyperglycemia and hyperlipidemia etc.
摘要翻译：提供了一种融合蛋白，其包含人成纤维细胞生长因子21和胰高血糖素样肽-1或其类似物。还提供了包含融合蛋白的药物组合物，其可用于治疗或预防肥胖症，糖尿病，高血糖症和高脂血症等。

5. 发明授权

US08647278B2 Method and system for non-invasive intracranial pressure monitoring 失效
标题翻译：非侵入性颅内压监测方法与系统
公开(公告)号：US08647278B2
公开(公告)日：2014-02-11
申请号：US13280778
申请日：2011-10-25
申请人： Zhong Ji , Li Yang , Shuang Yang , Mingxi Zhao
发明人： Zhong Ji , Li Yang , Shuang Yang , Mingxi Zhao
IPC分类号： A61B8/00
CPC分类号： A61B8/04 , A61B5/026 , A61B5/031 , A61B5/04842 , A61B5/7246 , A61B8/0816 , A61B8/488 , A61B8/5223 , A61B2562/0215
摘要： Disclosed embodiments include a system and a method for determining intracranial pressure (ICP) of a subject that comprises: (a) applying transcranial Doppler (TCD) to determine the middle cerebral artery (MCA) velocity of the subject and estimating changes in the ICP continuously based on a functional mapping that relates arterial blood pressure (ABP) and cerebral blood flow velocity (CBFV) to ICP, resulting in an estimated ICP trend; (b) generating a flash visual evoked potential (FVEP) on the subject, processing a detected FVEP signal and obtaining an estimated ICP; and (c) combining the estimated ICP trend from TCD CBFV and ABP with the estimated ICP obtained by signal processing of the detected FVEP signal to periodically correct the trend and obtain a non-invasive measure of ICP.
摘要翻译：公开的实施例包括用于确定受试者的颅内压（ICP）的系统和方法，其包括：（a）施加经颅多普勒（TCD）以确定受试者的中脑动脉（MCA）速度并连续估计ICP的变化基于将动脉血压（ABP）和脑血流速度（CBFV）与ICP相关的功能映射，导致估计的ICP趋势; （b）在对象上产生闪光视觉诱发电位（FVEP），处理检测到的FVEP信号并获得估计的ICP; 和（c）将来自TCD CBFV和ABP的估计ICP趋势与通过检测到的FVEP信号的信号处理获得的估计的ICP结合，以周期性地校正趋势并获得ICP的非侵入性测量。

6. 发明授权

US08555710B2 Systems and methods for analyzing liquids under vacuum 有权
标题翻译：在真空下分析液体的系统和方法
公开(公告)号：US08555710B2
公开(公告)日：2013-10-15
申请号：US13047025
申请日：2011-03-14
申请人： Xiao-Ying Yu , Li Yang , James P. Cowin , Martin J. Iedema , Zihua Zhu
发明人： Xiao-Ying Yu , Li Yang , James P. Cowin , Martin J. Iedema , Zihua Zhu
IPC分类号： G01N1/00 , G01F23/00
CPC分类号： G01N23/2204
摘要： Systems and methods for supporting a liquid against a vacuum pressure in a chamber can enable analysis of the liquid surface using vacuum-based chemical analysis instruments. No electrical or fluid connections are required to pass through the chamber walls. The systems can include a reservoir, a pump, and a liquid flow path. The reservoir contains a liquid-phase sample. The pump drives flow of the sample from the reservoir, through the liquid flow path, and back to the reservoir. The flow of the sample is not substantially driven by a differential between pressures inside and outside of the liquid flow path.An aperture in the liquid flow path exposes a stable portion of the liquid-phase sample to the vacuum pressure within the chamber. The radius, or size, of the aperture is less than or equal to a critical value required to support a meniscus of the liquid-phase sample by surface tension.
摘要翻译：用于支持液体抵抗腔室中的真空压力的系统和方法可以使得能够使用基于真空的化学分析仪器来分析液体表面。不需要电气或液体连接来通过室壁。该系统可以包括储存器，泵和液体流动路径。储层包含液相样品。泵驱动样品从贮存器的流动，通过液体流动路径返回储存器。样品的流动基本上不受液体流路内部和外部压力差的驱动。液体流路中的孔将液相样品的稳定部分暴露于室内的真空压力。孔的半径或尺寸小于或等于通过表面张力支撑液相样品的弯液面所需的临界值。

7. 发明申请

US20100234560A1 DIAMOND COATING BY LIVING POLYMERIZATION 有权
标题翻译：通过生物聚合制备金刚石涂层
公开(公告)号：US20100234560A1
公开(公告)日：2010-09-16
申请号：US12463414
申请日：2009-05-10
申请人： Matthew R. Linford , Li Yang , Landon Wiest
发明人： Matthew R. Linford , Li Yang , Landon Wiest
IPC分类号： C08G83/00 , C08G65/00
CPC分类号： C08G65/2603 , C08L71/02 , Y10T428/31511 , Y10T428/31938
摘要： A method for coating a diamond where an initiation site is provided on the diamond surface or initiation of a living polymerization on the site and the initiation site is reacted with a monomer having a site the reacts with and bonds to the initiation site to form an chemically attached chain with a new initiation site on the chain for further reaction with a monomer. An article with a coating upon a diamond surface, the coating the reaction product of a living polymerization reaction with initiation site on the diamond surface.
摘要翻译：金刚石涂层方法，其中在金刚石表面上提供起始部位或起始部位和起始部位的活性聚合反应与具有与起始部位反应并与起始部位键合的单体形成化学反应在链上具有新的起始位点，以进一步与单体反应。在金刚石表面上具有涂层的物品，将活性聚合反应的反应产物与金刚石表面上的起始位点一起涂覆。

8. 发明申请

US20100198948A1 DYNAMIC WEB SERVICE DEPLOYMENT AND INTEGRATION 有权
标题翻译：动态WEB服务部署和集成
公开(公告)号：US20100198948A1
公开(公告)日：2010-08-05
申请号：US12364970
申请日：2009-02-03
申请人： Li Yang , Balamurugan Kuthanoor
发明人： Li Yang , Balamurugan Kuthanoor
IPC分类号： G06F15/177
CPC分类号： G06F9/5055
摘要： Embodiments include a computer system that receives registration information from a service provider registering web services with the dynamic web service configuration store, where the registration information indicates a mapping of which web service components are to be used with corresponding user requests. The computer system receives a request from a user requesting a portion of web service functionality and provides the web service functionality using the web service component indicated in the mapping. The computer system receives an indication from the service provider that various web service components are to be updated, where the indication includes updated web service component portions. The computer system also dynamically updates the web service component, so that subsequent user requests for the same portion of web service functionality are processed using the updated web service component.
摘要翻译：实施例包括从服务提供者接收注册信息的计算机系统，该服务提供者与动态Web服务配置存储区注册Web服务，其中注册信息指示将使用哪个Web服务组件与对应的用户请求的映射。计算机系统从请求一部分web服务功能的用户接收请求，并使用映射中指示的Web服务组件提供Web服务功能。计算机系统从服务提供商接收到将要更新各种web服务组件的指示，其中指示包括更新的web服务组件部分。计算机系统还动态地更新Web服务组件，使得使用更新的web服务组件来处理对Web服务功能的相同部分的后续用户请求。

9. 发明申请

US20100089752A1 FUNCTIONALIZATION OF HYDROGEN DEUTERIUM-TERMINATED DIAMOND 审中-公开
标题翻译：氢化终止金刚石的功能化
公开(公告)号：US20100089752A1
公开(公告)日：2010-04-15
申请号：US12564901
申请日：2009-09-22
申请人： Matthew R. Linford , Li Yang
发明人： Matthew R. Linford , Li Yang
IPC分类号： B01D15/08 , C01B31/06 , B01D53/02 , B01D57/02
CPC分类号： B01J20/3248 , B01J20/286 , B01J20/3204 , B01J2220/54 , C01B32/28 , G01N30/7266 , G01N2030/743
摘要： Deuterium and hydrogen terminated diamond surfaces are functionalized with alkyl or aryl peroxide.
摘要翻译：氘和氢终止金刚石表面用烷基或芳基过氧化物官能化。

10. 发明申请

US20100072137A1 FUNCTIONALIZED GRAPHITIC STATIONARY PHASE AND METHODS FOR MAKING AND USING SAME 审中-公开
标题翻译：功能化的GRAPHITIC STATIONARY相和其制造和使用方法
公开(公告)号：US20100072137A1
公开(公告)日：2010-03-25
申请号：US12563646
申请日：2009-09-21
申请人： Matthew R. Linford , David Scott Jensen , Li Yang , Landon Wiest
发明人： Matthew R. Linford , David Scott Jensen , Li Yang , Landon Wiest
IPC分类号： B01J20/20 , B01D15/08 , B01J20/282 , B01J20/22
CPC分类号： B01J20/3244 , B01D15/26 , B01J20/20 , B01J20/286 , B01J20/3242 , B01J20/3246 , C01B32/20 , C01P2004/61 , C01P2006/12
摘要： Embodiments disclosed herein include functionalized graphitic stationary phase materials and methods for making and using these materials, including the use of these materials in separation technologies such as, but not limited to, chromatography and solid phase extraction. In an embodiment, a functionalized graphitic stationary phase material may be manufactured from high surface area porous graphitic carbon and a radical forming functionalizing agent. The radical forming functionalizing agent produces an intermediate that forms a covalent bond with the surface of the porous graphitic material and imparts desired properties to the surface of the graphitic carbon.
摘要翻译：本文公开的实施方案包括官能化石墨固定相材料以及用于制备和使用这些材料的方法，包括在分离技术例如但不限于色谱和固相萃取中使用这些材料。在一个实施方案中，官能化的石墨固定相材料可以由高表面积的多孔石墨碳和自由基形成官能化剂制成。自由基形成官能化剂产生与多孔石墨材料的表面形成共价键的中间体，并将所需的性质赋予石墨碳的表面。

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