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1. 发明申请

WO2016124784A1 MICROCAPSULES COMPRISING LUTEIN OR LUTEIN ESTER 审中-公开
标题翻译：包含LUTEIN或LUTEIN ESTER的微生物
公开(公告)号：WO2016124784A1
公开(公告)日：2016-08-11
申请号：PCT/EP2016/052619
申请日：2016-02-08
申请人： BASF SE
发明人： MUSAEUS, Nina , KRYLBO, Inge-Lise
IPC分类号： C09B61/00 , A61K9/20 , A61K9/50 , A61K31/047 , A61K31/015 , C07C403/00 , A23L33/105 , A23L5/44 , A23K20/179
CPC分类号： A23C9/152 , A23K20/10 , A23K20/158 , A23K20/163 , A23K20/179 , A23L2/52 , A23L2/58 , A23L5/44 , A23L29/25 , A23L33/105 , A23P10/30 , A23V2002/00 , A61K9/2081 , A61K9/5036 , A61K9/5089 , A61K31/047 , A61K31/65 , C09B61/00 , C09B67/0097
摘要： The invention relates to microcapsules comprising at least one active substance selected from lutein and lutein esters embedded in a matrix comprising gum acacia and optionally one or more other matrix components, wherein the content of said at least one active substance calculated as free lutein is from 0.5 to 25 % of total weight of the microcapsule, and which microcapsule does not comprise any added emulsifier. The invention further relates to a process of preparing the microcapsule as well as uses and products comprising the microcapsule.
摘要翻译：本发明涉及包含至少一种选自叶黄素和叶黄素的活性物质的微胶囊，所述活性物质包含在包含阿拉伯胶和任选的一种或多种其它基质组分的基质中，其中以游离叶黄素计算的所述至少一种活性物质的含量为0.5 至微胶囊总重量的25％，哪个微胶囊不包含任何添加的乳化剂。本发明还涉及制备微胶囊的方法以及包含微胶囊的用途和产品。

2. 发明申请

WO2012139891A1 SUBSTITUIERTE VINYL- UND ALKINYL-CYCLOHEXENOLE ALS WIRKSTOFFE GEGEN ABIOTISCHEN PFLANZENSTRESS 审中-公开
标题翻译：取代乙烯基和炔cyclohexenols为活动对非生物植物胁迫
公开(公告)号：WO2012139891A1
公开(公告)日：2012-10-18
申请号：PCT/EP2012/055479
申请日：2012-03-28
申请人： BAYER CROPSCIENCE AG , FRACKENPOHL, Jens , MÜLLER, Thomas , HEINEMANN, Ines , VON KOSKULL-DÖRING, Pascal , ROSINGER, Christopher, Hugh , HÄUSER-HAHN, Isolde , HILLS, Martin, Jeffrey
发明人： FRACKENPOHL, Jens , MÜLLER, Thomas , HEINEMANN, Ines , VON KOSKULL-DÖRING, Pascal , ROSINGER, Christopher, Hugh , HÄUSER-HAHN, Isolde , HILLS, Martin, Jeffrey
IPC分类号： C07D317/20 , C07C403/00 , C07D403/00
CPC分类号： A01N55/00 , A01N33/24 , A01N35/06 , A01N35/10 , A01N37/36 , A01N37/42 , A01N41/06 , A01N43/08 , A01N43/10 , A01N43/28 , A01N43/30 , A01N43/50 , A01N43/54 , C07C49/747 , C07C69/757 , C07C69/76 , C07C233/25 , C07C235/84 , C07C251/44 , C07C251/48 , C07C255/56 , C07C311/08 , C07C311/29 , C07C403/00 , C07C2601/02 , C07C2601/10 , C07C2601/16 , C07D317/20
摘要： Die Erfindung betrifft substituierte Vinyl- und Alkinyl-cyclohexenole der allgemeinen Formel (I) und deren Salze, wobei die Reste R 1 , R 2 , R 3 , R 4 , R 5 , [X-Y] und Q die in der Beschreibung angegebenen Definitionen besitzen, Verfahren zu deren Herstellung und ihre Verwendung zur Steigerung der Stresstoleranz in Pflanzen gegenüber abiotischem Stress, und/oder zur Erhöhung des Pflanzenertrags.
摘要翻译：本发明涉及通式（I）和它们的盐，其中基团R1，R2，R3，R4，R5，[XY]和Q具有在说明书中给出的定义的取代的乙烯基和炔cyclohexenols，它们的制备方法及其对提高植物抗逆性非生物胁迫，和/或提高植物产量的用途。

3. 发明申请

WO2007037791A3 SUSTAINABLE SUPPLY OF BIOACTIVE MARINE PRODUCTS 审中-公开
标题翻译：生物海产品的可持续供应
公开(公告)号：WO2007037791A3
公开(公告)日：2009-04-30
申请号：PCT/US2006022462
申请日：2006-06-09
申请人： UNIV FLORIDA ATLANTIC , KERR RUSSELL G , BRUECK THOMAS
发明人： KERR RUSSELL G , BRUECK THOMAS
IPC分类号： C12P23/00 , C07C403/00 , C12P7/02
CPC分类号： C12P1/04 , C12P5/007 , C12P7/02 , C12P7/04 , C12P7/22 , C12P7/24
摘要： The identification and characterization of the sources of terpenes from the soft corals Leptogorgia minimata (LM, formerly Lophogorgia spp., Family: Gorgoniidae), Swifita exertia (SE, Family: Plexauridae), Iciligorgia schrammi (IS, Family: Anthothelidae), Eunicea fusca, Eiythropodium caribaeorum or Plexaurella sp. through direct culture of microbial populations derived from coral homogenates.
摘要翻译：来自软珊瑚Leptogorgia minimata（LM，以前的Lophogorgia spp。，Family：Gorgoniidae），Swifita exertia（SE，Family：Plexauridae），Iciligorgia schrammi（IS，Family：Anthothelidae），Eunicea fusca的萜烯来源的鉴定和表征，Eiythropodium caribaeorum或Plexaurella sp。通过直接培养来自珊瑚匀浆的微生物群落。

4. 发明申请

WO2005079464A3 VITAMIN D RECEPTOR ANTAGONISTS AND THEIR USE IN TREATING ASTHMA 审中-公开
标题翻译：维生素D受体拮抗剂及其在治疗哮喘中的应用
公开(公告)号：WO2005079464A3
公开(公告)日：2006-07-06
申请号：PCT/US2005005084
申请日：2005-02-16
申请人： WISCONSIN ALUMNI RES FOUND , DELUCA HECTOR F , BARYCKI RAFAL , RIVERA-BERMUDEZ MOISES A , PLUM LORI A , CLAGETT-DAME MARGARET
发明人： DELUCA HECTOR F , BARYCKI RAFAL , RIVERA-BERMUDEZ MOISES A , PLUM LORI A , CLAGETT-DAME MARGARET
IPC分类号： A61K31/59 , C07C401/00 , C07C403/00
CPC分类号： C07C401/00 , C07C2601/02
摘要： Various compounds such as those having the formula (I) and (XIV) where the variables have the values described herein antagonize the vitamin D receptor and are useful in treating conditions such as asthma and in preparing medicaments for use in antagonizing the vitamin D receptor or treating conditions such as asthma.
摘要翻译：各种化合物，例如具有式（I）和（XIV）的化合物，其中变量具有本文所述的值，其拮抗维生素D受体并且可用于治疗诸如哮喘的病症和用于制备用于拮抗维生素D受体的药物或治疗哮喘等症状。

5. 发明申请

WO2004085656A3 ENHANCED ACCUMULATION OF CAROTENOIDS IN PLANTS 审中-公开
标题翻译：植物中增强的碳水化合物累积
公开(公告)号：WO2004085656A3
公开(公告)日：2004-11-11
申请号：PCT/GB2004001241
申请日：2004-03-22
申请人： SYNGENTA LTD , DRAKE CAROLINE RACHEL , PAINE JACQUELINE ANN MARY , SHIPTON CATHERINE ANN
发明人： DRAKE CAROLINE RACHEL , PAINE JACQUELINE ANN MARY , SHIPTON CATHERINE ANN
IPC分类号： C07C403/00 , C12N9/02 , C12N9/10 , C12N15/53 , C12N15/54 , C12N15/82 , A01H5/00 , A01H5/10 , C12N15/62
CPC分类号： C12N9/0083 , C12N9/1029 , C12N9/1085 , C12N15/825 , C12Y205/01032
摘要： The present invention relates to polynucleotides and their use in methods of increasing the carotenoid content of seeds. In particular the invention provides a polynucleotide comprising: (a) a region which comprises as operably linked components (i) a promoter which provides for seed preferred expression; and (ii) a nucleotide sequence derived from a bacterium which sequence encodes a carotene desaturase; and (iii) a transcription termination region; and (b) a further region which comprises as operably linked components (i) a promoter which provides for seed preferred expression; and (ii) a nucleotide sequence encoding a phytoene synthase which sequence is derived from maize (Zea sp.) or rice (Orzya sp.); and (iii) a transcription termination region. The disclosed polynucleotides are particularly suitable for use in production of rice seed which comprise high amounts of coloured carotenoids.
摘要翻译：本发明涉及多核苷酸及其在增加种子类胡萝卜素含量的方法中的用途。特别地，本发明提供了一种多核苷酸，其包含：（a）包含可操作连接的组分的区域（i）提供种子优选表达的启动子; 和（ii）衍生自序列编码胡萝卜素去饱和酶的细菌的核苷酸序列; 和（iii）转录终止区; 和（b）另外的区域，其包含可操作地连接的组分（i）提供种子优选表达的启动子; 和（ii）编码来自玉米（Zea sp。）或水稻（Orzya sp。）的序列的八氢番茄红素合酶的核苷酸序列; 和（iii）转录终止区。所公开的多核苷酸特别适用于生产含有大量有色类胡萝卜素的水稻种子。

6. 发明申请

WO9958611A3 PROCESS FOR EXTRACTING CAROTENES FROM CAROTENE-CONTAINING MATERIALS 审中-公开
标题翻译：从含碳材料中提取卡络的方法
公开(公告)号：WO9958611A3
公开(公告)日：2000-03-16
申请号：PCT/EP9903219
申请日：1999-05-11
申请人： PETER SIEGFRIED , DRESCHER MARTIN , WEIDNER ECKHARD
发明人： PETER SIEGFRIED , DRESCHER MARTIN , WEIDNER ECKHARD
IPC分类号： C07C403/00 , A61K39/00 , B01D11/00 , B60C9/20 , C07C403/24 , C09B61/00 , C09B67/54 , C11B1/10
CPC分类号： C07C403/24 , C09B61/00
摘要： A process for extracting carotenes from carotene-containing materials, in particular from fats and oils of biological origin, which provides for extraction of said carotene-containing material with an extractant comprising at least one member selected from the group consisting of acetonitrile, N-methylpyrrolidone, N,N-dimethylformamide, tetrahydrofuran, N,N-dimethylacetamide, furfurol, morpholine, 4-formylmorpholine, 4-acetylmorpholine, 4-methylmorpholine, 4-phenylmorpholine.
摘要翻译：一种从含有胡萝卜素的材料，特别是从生物来源的脂肪和油中提取胡萝卜素的方法，其提供含有至少一种选自乙腈，N-甲基吡咯烷酮，N，N-二甲基甲酰胺，四氢呋喃，N，N-二甲基乙酰胺，糠醛，吗啉，4-甲酰基吗啉，4-乙酰基吗啉，4-甲基吗啉，4-苯基吗啉。

7. 发明申请

WO1992018471A1 EXTRACTION OF CAROTENOIDS FROM NATURAL SOURCES 审中-公开
标题翻译：从天然来源提取卡培他酮
公开(公告)号：WO1992018471A1
公开(公告)日：1992-10-29
申请号：PCT/US1992002929
申请日：1992-04-09
申请人： HUMANETICS CORPORATION
发明人： HUMANETICS CORPORATION , GRAVES, Frederic, A. , GALLAHER, Daniel, D.
IPC分类号： C07C403/00
CPC分类号： C09B61/00 , C07C403/24
摘要： A carotenoid-enriched fraction is extracted from natural sources, such as carrots, by (i) separating the carotenoid-containing natural source into a carotenoid-containing liquid fraction and a pulp fraction, (ii) adding a carotenoid precipitation agent including calcium chloride, calcium hydroxide, calcium lactate or calcium glyconate to the liquid fraction to form a carotenoid-enriched solid precipitate, and (iii) separating the carotenoid-enriched solid precipitate from the carotenoid-depleted liquid portion.

8. 发明申请

WO2016151552A3 METHODS FOR IMPROVEMENT OF VISUAL FUNCTION AND COMPOSITIONS USED THEREIN 审中-公开
标题翻译：改善视觉功能的方法及其使用的组合物
公开(公告)号：WO2016151552A3
公开(公告)日：2016-11-03
申请号：PCT/IB2016051730
申请日：2016-03-25
申请人： OMNIACTIVE HEALTH TECH LTD
发明人： DESHPANDE JAYANT , JUTURU VIJAYA , GHANAM KHADIJA , DOYLE LYNDA
IPC分类号： A01N65/00 , A61K31/07 , A61P27/00 , A61P27/02 , C07C403/00
CPC分类号： A61K31/047 , A23L5/44 , A23V2002/00 , A61K9/4858 , A61K31/065 , A61K2300/00 , A23V2200/30 , A23V2250/211
摘要： Methods herein are described for improvement in visual function by administering macular carotenoid compositions containing an effective daily dose, to a subject in need thereof. More particularly, methods herein are described and include use of the compositions herein by identifying a subject in need thereof, administering a daily dose of lutein and/or zeaxanthin isomers, comprised of meso-zeaxanthin and R,R zeaxanthin, alone or in combination thereof, the composition also including at least one food grade excipient, and evaluating visual performance. The subject is exposed to light of variable wavelengths and intensity and is suffering from visual fatigue. The composition improves contrast sensitivity, glare performance, photo stress recovery, and/or macular pigment optical density, and thus alleviates visual fatigue. The composition is safe for human and other animals for consumption and can be used for improvement in visual health in the subject, when administered in an effective amount.
摘要翻译：描述了通过向有需要的受试者施用含有有效日剂量的黄斑类胡萝卜素组合物来改善视觉功能的方法。更具体地，描述了本文的方法，包括通过鉴定需要的受试者来使用本文的组合物，单独或组合地施用日内剂量的叶黄素和/或玉米黄质异构体，所述叶黄素和/或玉米黄质异构体由内消旋 - 玉米黄质和R，R玉米黄质组成，该组合物还包括至少一种食品级赋形剂，并评估视觉性能。该受试者暴露于可变波长和强度的光，并且遭受视觉疲劳。该组合物提高对比敏感度，眩光性能，光应力恢复和/或黄斑色素光密度，从而减轻视觉疲劳。组合物对人和其他动物的消费是安全的，并且当以有效量施用时可用于改善受试者的视觉健康。

9. 发明申请

WO2016124783A1 MICROCAPSULES COMPRISING LUTEIN OR LUTEIN ESTER 审中-公开
标题翻译：包含LUTEIN或LUTEIN ESTER的微生物
公开(公告)号：WO2016124783A1
公开(公告)日：2016-08-11
申请号：PCT/EP2016/052618
申请日：2016-02-08
申请人： BASF SE
发明人： MUSAEUS, Nina , KRYLBO, Inge-Lise
IPC分类号： A61K9/20 , A61K9/50 , A61K31/015 , A61K31/047 , C07C403/00 , C09B61/00 , A23L33/105 , A23L5/44 , A23K20/179
CPC分类号： A23L33/105 , A23K20/147 , A23K20/158 , A23K20/179 , A23L2/52 , A23L2/58 , A23L5/44 , A23L29/284 , A23P10/30 , A61K9/0095 , A61K9/146 , A61K9/1652 , A61K9/1658 , A61K9/167 , A61K9/2077 , A61K9/2081 , A61K9/5057 , A61K9/5089 , A61K31/065 , C09B61/00 , C09B67/0097
摘要： The invention relates to a microcapsule comprising at least one active substance selected from lutein and lutein esters embedded in a matrix comprising porcine gelatine or bovine gelatine and optionally one or more other matrix components, wherein the content of said at least one active substance calculated as free lutein is from 0.5 to 25 % of total weight of the microcapsule, and which microcapsule does not comprise any added emulsifier. The invention further relates to a process of preparing the microcapsule as well as uses and products comprising the microcapsule.
摘要翻译：本发明涉及一种微胶囊，其包含至少一种选自叶黄素和叶黄素的活性物质，所述叶黄素和叶黄素嵌入包含猪明胶或牛明胶和任选的一种或多种其它基质组分的基质中，其中所述至少一种活性物质的含量以游离态叶黄素占微胶囊总重量的0.5〜25％，微胶囊不含任何添加的乳化剂。本发明还涉及制备微胶囊的方法以及包含微胶囊的用途和产品。

10. 发明申请

WO2008091686A3 SYNTHESIS OF 1a-FLUORO-25-HYDROXY-16-23E-DIENE-26,27-BISHOMO-20-EPI-CHOLECALCIFEROL 审中-公开
标题翻译： 1α-氟-25-羟基-16-23E-二烯-26,27-二肉豆蔻-20-烯-D-胆甾醇的合成
公开(公告)号：WO2008091686A3
公开(公告)日：2008-10-09
申请号：PCT/US2008000970
申请日：2008-01-25
申请人： BIOXELL SPA , MAEHR HUBERT , USKOKOVIC MILAN R
发明人： MAEHR HUBERT , USKOKOVIC MILAN R
IPC分类号： A61K31/59 , C07C401/00 , C07C403/00
CPC分类号： C07C401/00 , C07B2200/07 , C07C29/48 , C07C45/516 , C07C67/08 , C07C67/29 , C07C67/293 , C07C67/297 , C07C67/343 , C07C69/013 , C07C69/732 , C07C309/73 , C07C2601/16 , C07C2602/24 , C07C2602/28 , C07C35/32 , C07C35/18 , C07C47/267 , C07C69/16 , C07C69/14 , C07C69/145
摘要： The invention provides a method of producing 20-methyl vitamin D 3 compounds of formula (I). The method includes hydroxylation, carbonyl reduction, fluoride substitution, epoxide deoxygenation, and Wittig-type couplings.
摘要翻译：本发明提供了制备式（I）的20-甲基维生素D 3化合物的方法。该方法包括羟基化，羰基还原，氟化物取代，环氧化物脱氧和Wittig型偶联。

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