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    • 5. 发明申请
    • ELECTROGENIC PUMP MOLECULE CONTROL
    • 电子泵分子控制
    • WO2007100872A3
    • 2008-10-02
    • PCT/US2007005200
    • 2007-02-28
    • UNIV SOUTH FLORIDACHEN WEI
    • CHEN WEI
    • C25B5/00C07C1/00C07C2/00C07C4/00C07C5/00C07C6/00
    • A61N1/32
    • Activation of electrogenic pump molecules can be realized by a dynamic entrainment procedure which includes two steps: synchronization of individual pump molecules to work at the same pumping pace, and gradual modulation of the synchronization frequency. We studied synchronization of the Na/K pump molecules in a physiological running mode by applying the concept of an electronic synchrotron to the biological system. Both theoretical analysis and experimental results showed that individual Na/K pump molecules can be synchronized by a well designed oscillating electric field. The synchronized pump currents show separated inward and outward pump currents and a magnitude ratio of 3:2 reflecting stoichiomatric number of the pump molecules.
    • 电动泵分子的激活可以通过动态夹带程序来实现,其包括两个步骤:单个泵分子以相同的泵送速度同步并且同步频率的逐渐调制。 我们通过将电子同步加速器的概念应用于生物系统,研究了生理运行模式下Na / K泵分子的同步。 理论分析和实验结果表明,单个Na / K泵分子可以通过精心设计的振荡电场同步。 同步的泵浦电流显示分离的向内和向外泵浦电流,并且3:2的幅度比反映了泵分子的化学计量数。