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1. 发明申请

WO2023028144A1 METHOD AND APPARATUS FOR SAFE AND EFFICACIOUS TREATMENT OF UROLOGICAL CONDITIONS WITH LASER ENERGY 审中-公开
公开(公告)号：WO2023028144A1
公开(公告)日：2023-03-02
申请号：PCT/US2022/041375
申请日：2022-08-24
申请人： IPG PHOTONICS CORPORATION
发明人： ALTSHULER, Gregory , YAROSLAVSKY, Ilya , ANDREEVA, Viktoriya , KOVALENKO, Anastasia , COYLE, Kevin , TRAXER, Olivier , VYBORNOV, Alexander
IPC分类号： A61B18/26 , A61B18/00 , A61B17/00
摘要： A laser system that includes a processing laser configured to generate a laser beam, a beam delivery system configured to direct the laser beam at a target, a user input device configured to receive input from a user, and a controller coupled to the processing laser and the user input device and configured to: receive initial user input date from the user input device, the initial user input data including at least one of: one or more properties of the beam delivery system, and one or more properties of the target, determine at least one initial laser operating parameter value and a corresponding initial laser operating parameter range based on the initial user input data, and electronically stored information, and control the processing laser using the at least one initial laser operating parameter value.

2. 发明申请

WO2022256734A1 NON-CONTACT LITHOTRIPSY USING PHOTONIC NANOPARTICLES 审中-公开
公开(公告)号：WO2022256734A1
公开(公告)日：2022-12-08
申请号：PCT/US2022/032336
申请日：2022-06-06
申请人： THE CLEVELAND CLINIC FOUNDATION
发明人： KRISHNA, Vijay , DE, Smita , HOULIHAN, Ian Thomas
IPC分类号： A61B18/26 , A61B18/20 , A61N5/06 , A61B18/28 , A61N5/067 , A61K41/00 , C01B32/152
摘要： Methods of non-contact lithotripsy are disclosed, wherein photonic nanoparticles are delivered in the vicinity of kidney stones, e.g. within a kidney. The nanoparticles then are irradiated with non-ionizing electromagnetic radiation to activate the nanoparticles and fragment the stone. In preferred embodiments, the nanoparticles are placed effectively into contact with the kidney stone, via functionalizing the particles with ligands that will adhere to the known or anticipated chemical composition of the stone surface. A combination of a kidney stone and a photonic nanoparticle in its vicinity or adhered thereto at its surface also is disclosed.

3. 发明申请

WO2022235762A1 SMART IRRIGATION AND ASPIRATION SYSTEM AND METHOD 审中-公开
公开(公告)号：WO2022235762A1
公开(公告)日：2022-11-10
申请号：PCT/US2022/027625
申请日：2022-05-04
申请人： IPG PHOTONICS CORPORATION
发明人： YAROSLAVSKY, Ilya , PILIPETSKII, Sergei , BOUTOUSSOV, Dmitri , ALTSHULER, Gregory , TRAXER, Olivier , OSTROVSKY, Isaac , KOVALENKO, Anastasiya , STUKALIN, Felix
IPC分类号： A61M1/00 , A61M39/22 , A61B18/26
摘要： An irrigation and aspiration system that includes a catheter shaft haying a distal end that is in fluid communication with an interior of a kidney, an irrigation. channel and an aspiration channel extending through the shaft, a bypass channel fluidly coupled, with the irrigation channel and the aspiration channel, a bypass valve configured to control a level of fluid communication between the irrigation and aspiration channels via the bypass channel, an aspiration pump, at least one valve disposed, on the aspiration channel and configured to provide a pulsed flow of fluid in the aspiration channel, a pressure sensor in fluid communication with an interior of the kidney, and a controller configured to: receive at least one pressure measurement, compare the measured pressure to a threshold, and based on the comparison, send a control command to at least one of the bypass valve, aspiration pump, and the at least one valve.

4. 发明申请

WO2021247685A1 SYSTEM AND METHOD FOR MAINTAINING BALLOON INTEGRITY WITHIN INTRAVASCULAR LITHOTRIPSY DEVICE WITH PLASMA GENERATOR 审中-公开
公开(公告)号：WO2021247685A1
公开(公告)日：2021-12-09
申请号：PCT/US2021/035425
申请日：2021-06-02
申请人： BOSTON SCIENTIFIC SCIMED, INC. , BOLT MEDICAL, INC.
发明人： MASSIMINI, Daniel, Frank , MCGOWAN, Roger , FULLER, Jeffrey, Steven , LINDQUIST, Jeffrey, S. , PARSONS, Dave , SCHULTHEIS, Eric
IPC分类号： A61B18/02 , A61B18/04 , A61B18/042 , A61B18/1492 , A61B18/245 , A61B18/26 , A61B2017/00154 , A61B2018/00023 , A61B2018/00077 , A61B2018/00095 , A61B2018/00101 , A61B2018/00154 , A61B2018/00166 , A61B2018/0022 , A61B2018/00255 , A61B2018/00285 , A61B2018/00345 , A61B2018/00369 , A61B2018/00386 , A61B2018/00422 , A61B2018/0066 , A61B2018/2211 , A61B2018/2261 , A61B2018/2266 , A61B2018/2272 , A61B2018/263 , A61B2018/266 , A61B2090/0809
摘要： A catheter system (100) for treating a treatment site (106) within or adjacent to the vessel wall of a blood vessel (108), or the heart valve, includes an energy source (124), a balloon (104), an energy guide (122A), and a balloon integrity protection system (142). The energy source (124) generates energy, The balloon (104) is positionable substantially adjacent to the treatment site (106). The balloon (104) has a balloon wall (130) that defines a balloon interior (146). The balloon (104) is configured to retain a balloon fluid (132) within the balloon interior (146). The energy guide (122A) is configured to receive energy from the energy source (124) and guide the energy into the balloon interior (146) so that plasma is formed in the balloon fluid (132) within the balloon interior (146). The balloon integrity protection system (142) is operatively coupled to the balloon (104). The balloon integrity protection system (142) is configured to inhibit rupture of the balloon (104) due to the plasma formed in the balloon fluid (132) within the balloon interior (146) during use of the catheter system (100).

5. 发明申请

WO2021222572A1 METHODS AND SYSTEMS FOR SURFACTANT ENHANCED LASER-INDUCED VAPOR BUBBLES FOR USE IN LASER LITHOTRIPSY 审中-公开
公开(公告)号：WO2021222572A1
公开(公告)日：2021-11-04
申请号：PCT/US2021/029902
申请日：2021-04-29
申请人： THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE
发明人： HUTCHENS, Thomas, C. , GIGLIO, Nicholas, C. , FRIED, Nathaniel, M.
IPC分类号： A61B18/26
摘要： Methods and systems for surfactant enhanced laser-induced vapor bubbles for use in laser lithotripsy. Urinary tract stone disease is a common and costly disease that effects approximately 10% of the United States population. A preferred minimally invasive method for treatment of urinary tract stones is laser lithotripsy, which involves insertion of a flexible ureteroscope through the urinary tract to the stone's location, and then transmission of infrared (IR) laser energy through a flexible optical fiber, which is in turn placed through the single working channel of the ureteroscope. The IR laser energy is used for ablation of the urinary tract stone which is then removed. In order to have a more efficient ablation, the ureteroscope is fed with a surfactant composition which is flowed into the ureter and/or kidney of the subject. The laser causes larger bubbles to form in the surfactant composition, making a robust and longer lasting bubble.

6. 发明申请

WO2021203019A SHOCKWAVE AND PRESSURE WAVES FOR TREATMENT OF VIRUS OR BACTERIA-INDUCED EFFECTS IN HUMAN OR ANIMAL LUNGS 审中-公开
公开(公告)号：WO2021203019A
公开(公告)日：2021-10-07
申请号：PCT/US2021/025609
申请日：2021-04-02
申请人： SANUWAVE, INC. [US]/[US]
发明人： CIOANTA, Iulian
IPC分类号： A61B18/26 , A61N5/06 , A61N5/067 , A61N7/00 , G05B13/02 , A61B17/22012 , A61B2017/00809 , A61B2017/22025 , A61H2203/03 , A61H23/008
摘要： Shockwaves or modulated pressure waves are applied to targeted lung tissue of humans or animals, including lung tissue having a viral or bacterial infection or a chronic lung condition, to destroy or render innocuous different pathogens and treat the underlying chronic or acute medical conditions.

7. 发明申请

WO2021188233A1 OPTICAL ANALYZER ASSEMBLY AND METHOD FOR INTRAVASCULAR LITHOTRIPSY DEVICE 审中-公开
公开(公告)号：WO2021188233A1
公开(公告)日：2021-09-23
申请号：PCT/US2021/017604
申请日：2021-02-11
申请人： BOLT MEDICAL, INC.
发明人： COOK, Christopher, A. , SCHULTHEIS, Eric
IPC分类号： A61B18/26 , A61B18/24
摘要： A catheter system (100) for treating a treatment site (106) within or adjacent to a vessel wall (108) or a heart valve includes a light source (124), an inflatable balloon (104), a light guide (122A), and an optical analyzer assembly (142). The light source (124) generates light energy. The inflatable balloon (104) is positionable substantially adjacent to the treatment site (106). The inflatable balloon (104) has a balloon wall (130) that defines a balloon interior (146) that receives a balloon fluid (132). The light guide (122 A) receives light energy from the light source (124) at a guide proximal end (122P) and guides the light energy in a first direction (121F) toward a guide distal end (122D) and into the balloon interior (146). The optical analyzer assembly (142) is configured to optically analyze light energy emitted from the light guide (122A) in a second direction (121S) from the guide distal end (122D) toward the guide proximal end (122P) of the light guide (122A).

8. 发明申请

WO2021162855A1 SYSTEM AND METHOD FOR PRESSURE MONITORING WITHIN A CATHETER SYSTEM 审中-公开
公开(公告)号：WO2021162855A1
公开(公告)日：2021-08-19
申请号：PCT/US2021/015204
申请日：2021-01-27
申请人： BOLT MEDICAL, INC.
发明人： COOK, Christopher, A. , SCHULTHEIS, Eric
IPC分类号： A61B17/22 , A61B18/26
摘要： A catheter system (100) for treating a treatment site (106) includes an energy source (124), an inflatable balloon (104), an energy guide (122A), and a pressure sensor (258, 358). The inflatable balloon (104) is positionable substantially adjacent to the treatment site (106). The inflatable balloon (104) has a balloon wall (130) that defines a balloon interior (146) that receives a balloon fluid (132). The energy source (124) generates energy that is received by the energy guide (122 A) so that the energy guide (122A) can guide the energy into a balloon interior (146). The pressure sensor (258, 358) senses a balloon pressure of the balloon fluid (132). A method for disrupting calcification at the treatment site (106) includes the steps of generating energy with the energy source (124), positioning the inflatable balloon (104) substantially adjacent to the treatment site (106), the inflatable balloon (104) having the balloon wall (130) that defines the balloon interior (146), the balloon interior (146) being configured to receive the balloon fluid (132), receiving energy from the energy source (124) with the energy guide (122A), guiding the energy from the energy source (124) into the balloon interior (146) with the energy guide (122 A); and sensing a balloon pressure of the balloon fluid (132) with a pressure sensor (258, 358).

9. 发明申请

WO2021091590A1 A METHOD OF TREATING THE LUNGS 审中-公开
公开(公告)号：WO2021091590A1
公开(公告)日：2021-05-14
申请号：PCT/US2020/024898
申请日：2020-03-26
申请人： TISSUE REGENERATION TECHNOLOGIES, LLC
发明人： WARLICK, John F. , FINNEY, John Patrick
IPC分类号： A61B18/26 , A61B8/00 , A61B17/225 , A61H9/00 , A61H23/00 , G10K11/28
摘要： A method of treating a patient exhibiting a lung disease or pulmonary disorder by applying shock waves or acoustic pulses directed to impinge lung tissue of the lung or lungs exhibiting a lung disease or pulmonary disorder, has the steps of: activating an acoustic shock wave or acoustic wave generator or source to emit acoustic shock waves or pressure pulses from a fixed acoustic wave source or a handheld shock wave or pressure pulse head; and administering a plurality of acoustic waves in a pressure pulse or shock wave pattern within the lung tissue of less than 10.0 mJ/mm2 per shock wave, the plurality of acoustic waves in a pressure pulse or shock wave pattern being directed to a portion of the lung exhibiting the lung disease or pulmonary disorder.

10. 发明申请

WO2020263685A1 LIGHT GUIDE PROTECTION STRUCTURES FOR PLASMA SYSTEM TO DISRUPT VASCULAR LESIONS 审中-公开
公开(公告)号：WO2020263685A1
公开(公告)日：2020-12-30
申请号：PCT/US2020/038517
申请日：2020-06-18
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： MASSIMINI, Daniel, Frank , KRAUTKREMER, Daniel, Lee , SHAO, Haiping , McGOWAN, Roger, W.
IPC分类号： A61B18/24 , A61B18/26
摘要： A catheter system (100) includes a catheter (101) having an elongate shaft (102), a balloon (122) and a light guide (110). The balloon (122) expands from a collapsed configuration (1002) to a first expanded configuration (1004). The light guide (110) is disposed along the elongate shaft (102) and is in optical communication with a light source (116) and a balloon fluid (124). A first portion (1104) of the light guide (1102) extends into a recess (1106) defined by the elongate shaft (102). A protection structure (1110, 1410, 1510, 1610, 1710, 1810) is disposed within the recess (1106) and is in contact with the first portion (1104) of the light guide (1102). The light source (116) provides pulses of light to the balloon fluid (124), thereby initiating plasma formation and rapid formation of bubbles (1114) within the balloon (122), thereby imparting pressure waves (1016) upon a treatment site (1014). The protection structure (1110, 1410, 1510, 1610, 1710, 1810) can provide structural protection from the pressure waves (1016) to the first portion (1104) of the light guide (1102).

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