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1. 发明申请

WO2023049225A2 SCATTERING-TYPE SCANNING NEAR-FIELD OPTICAL MICROSCOPY WITH AKIYAMA PIEZO-PROBES 审中-公开
公开(公告)号：WO2023049225A2
公开(公告)日：2023-03-30
申请号：PCT/US2022/044311
申请日：2022-09-22
申请人： THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK , YALE UNIVERSITY
发明人： DAPOLITO, Michael , LIU, Megkun , CHEN, Xinzhong , GOZAR, Adrian
IPC分类号： G02B6/122 , A61B18/22 , G01Q20/04 , G02B21/00
摘要： A scattering-type scanning near-field optical microscope at cryogenic temperatures (cryo-SNOM) configured with Akiyama probes for studying low energy excitations in quantum materials present in high magnetic fields. The s-SNOM is provided with atomic force microscopy (AFM) control, which predominantly utilizes a laser-based detection scheme for determining the cantilever tapping motion of metal-coated Akiyama probes, where the cantilever tapping motion is detected through a piezoelectric signal. The Akiyama-based cryo-SNOM attains high spatial resolution, good near-field contrast, and is able to perform imaging with a significantly more compact system capable of handling simultaneous demands of vibration isolation, low base temperature, precise nano-positioning, and optical access. Results establish the potential of s-SNOM based on self-sensing piezo-probes, which can easily accommodate near-IR and far-infrared wavelengths and high magnetic fields. Using a tuning fork-based Akiyama probe provides nano-imaging capability at room and low temperatures and is used for near-field photocurrent mapping.

2. 发明申请

WO2023034579A1 AN APPARATUS AND METHOD FOR FRACTIONAL ABLATIVE TREATMENT OF TISSUE 审中-公开
公开(公告)号：WO2023034579A1
公开(公告)日：2023-03-09
申请号：PCT/US2022/042478
申请日：2022-09-02
申请人： IPG PHOTONICS CORPORATION
发明人： PAITHANKAR, Dilip , YAROSLAVSKY, Ilya , ALTSHULER, Gregory , ARKHIPOVA, Valeriya , TYRTYSHNYY, Valentin , MYASNIKOV, Daniil , LARIONOV, Igor , GULYASHKO, Alexander , NOSOV, Mikhail
IPC分类号： A61B18/20 , A61B18/22 , A61B18/00
摘要： A device for performing treatment of biological tissue that includes a laser system configured to provide a laser beam having a wavelength within a range of 3.0 microns (μm) to 3.25 μm inclusive and a spot size within a range of 10 μm to 45 μm inclusive, and a controller coupled to the laser system and configured to scan the laser beam over the biological tissue in an injury pattern, the injury pattern having a pitch that is sized to be in a range of 0.1 mm to 1 mm inclusive.

3. 发明申请

WO2022265835A1 SYSTEM AND APPARATUS FOR PHOTOLUMINESCENT LASER DELIVERY FIBER 审中-公开
公开(公告)号：WO2022265835A1
公开(公告)日：2022-12-22
申请号：PCT/US2022/030926
申请日：2022-05-25
申请人： C. R. BARD, INC.
发明人： FRANKLIN, Jeff, E.
IPC分类号： A61B18/22 , G02B6/44 , G02B6/00
摘要： An optical fiber cable is disclosed that includes an outer jacket and a plurality of cores including a first core and a second core. A plurality of channels can extend outwardly from the second core toward the outer jacket. The outer jacket can include a material doped with a photoluminescent material configured to absorb energy from light propagating along the second core causing photoluminescence. The optical fiber cable may include cladding surrounding the first and second cores and the plurality of channels. The first core may propagate a first laser beam having wavelength of substantially 1940 nanometers while the second core and the plurality of channels may propagate a second laser beam having a wavelength of within the range of 360 - 830 nanometers. A system for providing a medical treatment including a first medical instrument optically coupled to the optical fiber cable is also disclosed.

4. 发明申请

WO2022260650A1 OPTICAL SURFACE APPLICATOR WITH INTEGRATED DIFFUSER 审中-公开
公开(公告)号：WO2022260650A1
公开(公告)日：2022-12-15
申请号：PCT/US2021/036312
申请日：2021-06-08
申请人： LUMEDA INC.
发明人： MACDOUGALL, Trevor , YANG, Yi
IPC分类号： A61B18/22 , A61B18/20 , A61K9/70 , A61M35/00 , A61N5/06
摘要： A therapeutic light delivery apparatus and method are disclosed. The apparatus includes a light source and an integrated optical applicator. The integrated optical applicator includes a plurality of light emitting devices and detector fibers fixedly spatially positioned within a flexible matrix material. The light emitting devices can be positioned a predetermined distance from an application side of the integrated optical applicator comprising an accurate and repeatable standoff position. A flexible matrix material is disclosed having a high scattering coefficient to produce a uniform irradiance pattern and predetermined fluence. A method of performing a photodynamic therapy procedure is disclosed that includes providing an integrated optical applicator couple to a therapy light source, providing a photosensitizing drug to a tissue of a patient, positioning an application side of the integrated optical applicator against a target area of the tissue, delivering a therapy light to the target area, and producing an irradiance pattern.

5. 发明申请

WO2022258554A1 OPTICAL SCALPEL AND METHOD OF MANUFACTURING 审中-公开
公开(公告)号：WO2022258554A1
公开(公告)日：2022-12-15
申请号：PCT/EP2022/065294
申请日：2022-06-06
申请人： UNIVERSITA' DELLA CALABRIA
发明人： CAPUTO, Roberto , FERRARO, Antonio , LIO, Giuseppe Emanuele
IPC分类号： A61B18/22
摘要： The present invention relates to an optical scalpel, comprising: - A laser (7) designed to emit an electromagnetic radiation with a wavelength comprised between 300 nm and 1500 nm; - An optical fibre (11) defining a first and a second end, the optical fibre being designed to guide the electromagnetic radiation emitted by the laser (7); - A transducer device (1) of light energy into thermal energy positioned on the first end of the optical fibre and comprising: o A first continuous layer of metallic material (3), with a thickness comprised between 5 nanometres and 150 nanometres; o A first layer of dielectric material (4), with a thickness comprised between 5 nanometres and 300 nanometres; o A second continuous layer of metallic material (5), with a thickness comprised between 5 nanometres and 150 nanometres.

6. 发明申请

WO2022045688A1 지방제거용 시술기기 审中-公开
公开(公告)号：WO2022045688A1
公开(公告)日：2022-03-03
申请号：PCT/KR2021/011165
申请日：2021-08-23
申请人： 임시연
发明人： 임시연 RHIM, Si Youn
IPC分类号： A61B18/22 , A61B18/24 , A61M1/00 , A61B18/00 , A61B18/20
摘要： 본 개시는 지방제거용 시술기기에 관한 것으로, 본 개시에서는 도파관의 분해지방 흡입통로 상에, '절연성 재질을 가지면서, 도파관에 고정된 상태에서, 광섬유를 속박상태로 지지함으로써, 광섬유의 변형 및 도파관과의 접촉을 사전 차단시킬 수 있는 광섬유 지지체'를 추가로 배치/제공하고, 이를 통해, 광섬유 측에서, 지방제거 시술 국면에서, 여러 원인(예컨대, 자체 중량, 인체 조직과의 접촉 등)이 작용한다 하더라도, 광섬유 지지체의 강한 속박작용을 기반으로, 일련의 변형(예컨대, 굴곡진 형상 등)을 억제/통제 받으면서, 도파관과의 직접적인 접촉 및 이에 기인한 파손을 효과적으로 회피할 수 있도록 유도함으로써, 결국, 지방제거 시술주체(예컨대, 지방제거 시술 의료진 등) 측에서, 파손된 광섬유 조각의 무분별한 인체 유입/확산에 따른 심각한 문제점을 손쉽게 회피하면서, 고주파/레이저 동시발진, 분해지방 동시흡입 등이 병행 가능한 효과적인 지방제거 시술을 정상적으로 시행할 수 있도록 지원할 수 있다.

7. 发明申请

WO2022035979A1 SELF-CONTAINED SURGICAL SMOKE DETOXIFIER 审中-公开
公开(公告)号：WO2022035979A1
公开(公告)日：2022-02-17
申请号：PCT/US2021/045572
申请日：2021-08-11
申请人： PATIENTPOCKET LLC
发明人： SEFTEL, Allen, D.
IPC分类号： B01D46/48 , A61B18/00 , A61B50/30 , A61M1/00 , B01D46/12 , H01S3/02 , H01S3/03 , A61B18/22 , A61B2218/008 , B01D2273/30 , B01D46/0043 , B01D46/0049
摘要： An integrated surgical smoke filtration and detoxification system. The system includes a housing that may include an interior chamber for detoxification and filtration performed by a detoxification system. The detoxification system may include a suction device and a filter and may be used to receive surgical smoke through a first portion of the chamber and exhaust detoxified surgical smoke through a second portion of the chamber.

8. 发明申请

WO2022020208A1 LASER TREATMENT USING ACOUSTIC FEEDBACK 审中-公开
公开(公告)号：WO2022020208A1
公开(公告)日：2022-01-27
申请号：PCT/US2021/042059
申请日：2021-07-16
申请人： GYRUS ACMI, INC. D/B/A OLYMPUS SURGICAL TECHNOLOGIES AMERICA
发明人： POLEJAEV, Vladimir , BUKESOV, Sergey A. , SHELTON, Kurt G.
IPC分类号： A61B18/22 , A61B18/00 , A61B5/00 , A61B1/00
摘要： Systems, devices, and methods for automatic control of laser treatment of target structure in a body of a subject based on acoustic feedback in response to delivery of laser energy to the target are disclosed. An exemplary laser energy delivery system comprises a laser system to direct laser energy at a body target, and a controller circuit to receive an acoustic signal in response to delivery of laser energy to the target, and to measure acoustic properties from the acoustic signal. The control circuit may generate control signals for controlling the laser system to adjust laser energy output, or for controlling an actuator to adjust a position of a laser fiber distal end relative to the target to achieve a desired therapeutic effect.

9. 发明申请

WO2022013144A1 A LASER EQUIPMENT WITH A LASER SOURCE AND A BEAM DEFLECTOR 审中-公开
公开(公告)号：WO2022013144A1
公开(公告)日：2022-01-20
申请号：PCT/EP2021/069312
申请日：2021-07-12
申请人： EL.EN. S.P.A.
发明人： TAGLIAFERRI, Marco , BRUGIONI, Alfredo , GIOE', Luciano
IPC分类号： A61B18/22 , B23K26/064 , G02B6/34
摘要： The equipment comprises a first laser source (3) adapted to emit a laser beam (F3) and a first output (1.3) which can be interfaced with an optical fiber (9), for conveying the first laser beam (F3) into the optical fiber (9). A deflector (11) moveable between a first inactive position and a second active position allows to direct the laser beam (F3) at least partially into a cladding (9.2) surrounding the core (9.1) of the optical fiber (9) interfaced with the first output (1.3).

10. 发明申请

WO2021262355A1 PROTECTING NON-TARGET TISSUE DURING ABLATION PROCEDURES AND RELATED SYSTEMS AND METHODS 审中-公开
公开(公告)号：WO2021262355A1
公开(公告)日：2021-12-30
申请号：PCT/US2021/033461
申请日：2021-05-20
申请人： MEDTRONIC NAVIGATION, INC.
发明人： DROWN, Christine , VINCELETTE, Rebecca
IPC分类号： A61B18/22 , A61B18/20 , A61B2017/00128 , A61B2018/00446 , A61B2018/00452 , A61B2018/00511 , A61B2018/00529 , A61B2018/00577 , A61B2018/00642 , A61B2018/0066 , A61B2018/00666 , A61B2018/00678 , A61B2018/00708 , A61B2018/00714 , A61B2018/00898 , A61B2090/0409 , A61B2090/049 , A61B90/04
摘要： Systems and methods for protecting non-target tissue from damage during a medical procedure for disrupting target tissue via heat application are disclosed. Data associated with the target tissue to be disrupted may be received. Based on the received data, one or more non-target objects of tissue that may be affected by the applied heat are identified. Both a temperature threshold and thermal dose threshold for each of the one or more non-target objects may be generated. Both the temperature and the thermal dose of each of the one or more non-target objects may be evaluated during performance of the medical procedure. A response may be generated when either the evaluated temperature of any of the one or more non-target objects reaches the corresponding temperature threshold or the thermal dose of any of the one or more non-target objects reaches the corresponding thermal dose threshold.

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