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1. 发明申请

WO2023089397A1 SURGICAL CONTACT LENS SYSTEM WITH A PATIENT CONTACT LENS 审中-公开
公开(公告)号：WO2023089397A1
公开(公告)日：2023-05-25
申请号：PCT/IB2022/059479
申请日：2022-10-04
申请人： ALCON INC.
发明人： BOR, Zsolt
IPC分类号： G02C7/04 , A61F9/008 , A61F9/009
摘要： In certain embodiments, a surgical contact lens system for ophthalmic treatment with a laser beam includes a patient contact lens and a surgical contact lens. The patient contact lens reduces one or more refractive errors of the eye and has a concave surface and a convex surface. The concave surface is to be disposed outwardly from a cornea of an eye. The surgical contact lens has an eye end to be disposed outwardly from the convex surface of the patient contact lens. The surgical contact lens includes a frame and an optical component coupled to the frame. The patient contact lens reduces pressure from the surgical contact lens to reduce corneal folding of a posterior surface of the cornea. The optical component of the surgical contact lens and the patient contact lens transmit the laser beam to treat the eye.

2. 发明申请

WO2023084482A1 PATIENT INTERFACE FOR OPHTHALMIC LASER SURGERY EMPLOYING SCLERAL SUPPORT STRUCTURES TO REDUCE INTRAOCULAR PRESSURE 审中-公开
公开(公告)号：WO2023084482A1
公开(公告)日：2023-05-19
申请号：PCT/IB2022/060936
申请日：2022-11-14
申请人： AMO DEVELOPMENT, LLC
发明人： LAGARTO, Christina , GARCIA, Jose , HANNON, Trevor , LOW, Vyechi
IPC分类号： A61F9/009
摘要： A patient interface device for an ophthalmic surgical laser system includes a lens cone component for coupling to the laser system and a suction ring component for coupling to the patient's eye. The suction ring includes a gripper with an opening for receiving and retaining the lens cone, and a flexible skirt joined to the gripper for coupling to the eye with a vacuum force. The flexible skirt includes a circular inner edge and a circular outer edge for contacting the eye surface, and a plurality of circumferentially distributed scleral support protrusions protruding from a circumferential side wall. The end surface of the scleral support protrusions are sloped in a side cross-sectional view. The scleral support protrusions have a length to width ratio from 1.1 to 2.1, and an arc-angle ratio of the scleral support protrusions to the gaps between them is from 2.2 to 3.0. The scleral support protrusions contact the surface of the eye when the skirt is docked to the eye, which minimize intraocular pressure increase due to docking and applanation while still achieving a good vacuum seal between the suction ring and the eye. The scleral support protrusions function to prevent major deformation of the sclera when the cornea is applanated.

3. 发明申请

WO2023042130A1 PATIENT INTERFACES FOR COOLING EYE TISSUE 审中-公开
公开(公告)号：WO2023042130A1
公开(公告)日：2023-03-23
申请号：PCT/IB2022/058739
申请日：2022-09-15
申请人： ALCON INC.
发明人： ABRAHAM, Mario , WITTNEBEL, Michael
IPC分类号： A61F9/009
摘要： A patient interface for an ophthalmic laser system includes an interface portion and an attachment portion. The interface portion includes a transmissive portion and an interface wall. The transmissive portion allows a laser beam through to the cornea of an eye to perform an ophthalmic procedure. The interface wall is disposed outwardly from the transmissive portion. The attachment portion couples the interface portion to a region of the cornea to allow the laser beam through to the cornea to perform the ophthalmic procedure. The attachment portion also decreases the temperature of the region during the ophthalmic procedure.

4. 发明申请

WO2021170664A1 SYSTEM, KONTAKTVORRICHTUNG UND VERFAHREN ZUM HERSTELLEN EINER KONTAKTVORRICHTUNG 审中-公开
公开(公告)号：WO2021170664A1
公开(公告)日：2021-09-02
申请号：PCT/EP2021/054575
申请日：2021-02-24
申请人： CARL ZEISS MEDITEC AG
发明人： PREUSS, Dirk , WIRTH, Andreas
IPC分类号： A61F9/009
摘要： Es wird ein System vorgeschlagen umfassend ein Kontaktelement (40) zur Fixierung der relativen geometrischen Lage eines Patientenauges zu einem Laser-Applikator eines ophthalmologischen Lasertherapiesystems, und ein Linsenelement (10) zum Einsetzen in das Kontaktelement (40), wobei das Kontaktelement (40) zum Aufnehmen des Linsenelements (10) an einer vorgegebenen Position ausgebildet ist, wobei das Linsenelement (10) eine Augenfläche (30) zum Berühren des Patientenauges oder zum luftdichten Begrenzen eines Hohlraums zwischen dem Linsenelement (10) und dem Patientenauge aufweist, wobei das Linsenelement (10) mindestens ein Vorsprungselement (25) zum Untergreifen von einem oder mehreren Halteelementen (42-47) des Kontaktelements (40) zum klebstofflosen Befestigen des Linsenelements (10) in dem Kontaktelement (40) mittels einer Schnappverbindung aufweist, wobei das Linsenelement (10) eine auf der Augenfläche (30) zugewandten Unterseite des Vorsprungselements (25) ausgebildete Linsenkontaktfläche (15) aufweist, wobei das Linsenelement (10) und das Kontaktelement (40) derart ausgebildet sind, dass das Linsenelement (10) derart in dem Kontaktelement (40) mittels der Schnappverbindung befestigbar ist, dass die Linsenkontaktfläche (15) mittels des mindestens einen Vorsprungselements (25) und des einen Halteelements (42-47) oder der mehreren Halteelemente (42-47) gegen ein auf einer Befestigungsfläche (49) des Kontaktelements (40) angeordnetes elastisches Ausgleichselement (50) zum Verringern der durch das eine Halteelement (42-47) oder die mehreren Halteelemente (42-47) auf das Linsenelement (10) wirkenden Kräfte gedrückt wird.

5. 发明申请

WO2021048723A1 SELECTIVE LASER STIMULATION OF CORNEAL STEM CELLS 审中-公开
公开(公告)号：WO2021048723A1
公开(公告)日：2021-03-18
申请号：PCT/IB2020/058300
申请日：2020-09-07
申请人： BELKIN LASER LTD.
发明人： BELKIN, Michael , SACKS, Zachary
IPC分类号： A61N5/06 , A61F9/008 , A61F9/009 , A61N5/067 , A61B18/00 , A61B18/20
摘要： Apparatus (20) for ophthalmic treatment includes an optical unit (30), which includes a camera (54), which is configured to capture an image of an eye (25) of a patient, a laser (48), which is configured to emit pulses of laser radiation, and beam conditioning and scanning optics (49, 50), which are configured to focus and direct the laser radiation to impinge on an anterior surface of the eye. A controller (44) is configured to analyze the image so as to identify a limbus of the eye, and to control the optical unit so that the laser radiation impinges on a set of one or more locations on the anterior surface of the eye that are in a vicinity of the limbus with a pulse duration and an energy selected so as to stem cells at the one or more locations.

6. 发明申请

WO2020165691A1 INTRAOCULAR PRESSURE MEASUREMENT FOR AN EYE DOCKED TO A LASER SYSTEM 审中-公开
公开(公告)号：WO2020165691A1
公开(公告)日：2020-08-20
申请号：PCT/IB2020/050876
申请日：2020-02-04
申请人： OPTIMEDICA CORPORATION
发明人： GONZALEZ, Javier G. , BRETT, Michael , GOODING, Phillip
IPC分类号： A61B3/16 , A61B3/07 , A61F9/009
摘要： A method for measuring the intraocular pressure (IOP) of an eye docked to an ophthalmic surgical laser system via a patient interface assembly. While the eye is docked to the laser system, and as the vertical force exerted on the eye by the patient interface fluctuates as the patient breaths and moves, the amount of corneal deformation is continuously measured by an optical coherence tomography device of the laser system and the force exerted on the eye is continuously measured by force sensors integrated in the patient interface assembly. Based on the real-time force signal and real-time corneal deformation signal, a controller calculates a linear relationship between force and corneal deformation, and determines the IOP of the docked eye by comparing a slope of the linear relationship against a pre-established slope vs. IOP calibration curve. The IOP of the docked eye can be used when setting laser treatment parameters.

7. 发明申请

WO2019079380A1 MEDICATION-COATED PATIENT INTERFACE DEVICE FOR OPHTHALMIC LASER SURGERY 审中-公开
公开(公告)号：WO2019079380A1
公开(公告)日：2019-04-25
申请号：PCT/US2018/056198
申请日：2018-10-17
申请人： AMO DEVELOPMENT, LLC
发明人： GARCIA, Jose L. , LOW, Vye Chi , JONAS, Audrey
IPC分类号： A61F9/009 , A61F9/007
CPC分类号： A61F9/0026 , A61F9/00754 , A61F9/009 , B29C45/0053 , B29C45/263 , B29C2045/0079 , B29K2083/00 , B29K2101/12 , B29L2031/7546
摘要： A patient interface device for use in ophthalmic surgery, which includes a rigid body and a suction ring joined to a lower end of the body, where the suction ring includes an annular skirt made of a soft and flexible material and located at a lower end of the suction ring, and where an inner surface, and optionally an outer surface, of the skirt is coated with medication. The medication includes one or more of the following types of medication: anti-inflammatory, antibiotic, numbing, lubricating, and anti-redness. The coating method may include dip coating, sputter deposition, ultrasonic-spraying, and spin-coating. The skirt may be formed by a process that increases its material porosity and/or surface roughness, and may be surface-treated to enhance adhesion and retention of the medication.

8. 发明申请

WO2019077497A1 OPHTHALMIC DOCKING SYSTEM WITH 3-DIMENSIONAL AUTOMATIC POSITIONING USING MAGNETIC SENSING ARRAY 审中-公开
公开(公告)号：WO2019077497A1
公开(公告)日：2019-04-25
申请号：PCT/IB2018/058020
申请日：2018-10-16
申请人： AMO DEVELOPMENT, LLC
发明人： LIU, Harvey I. , BEALE, John P.
IPC分类号： A61B90/20 , A61B90/90 , A61F9/009 , A61B17/00
摘要： A magnetic positioning system and related method for automated or assisted eye-docking in ophthalmic surgery. The system includes a magnetic field sensing system on a laser head and a magnet on a patient interface to be mounted on the patient's eye. The magnetic field sensing system includes four magnetic field sensors located on a horizontal plane for detecting the magnetic field of the magnet, where one pair of sensors are located along the X direction at equal distances from the optical axis of the laser head and another pair are located along the Y direction at equal distances from the optical axis. Based on relative magnitudes of the magnetic field detected by each pair of sensors, the magnetic field sensing system determines whether the patient interface is centered on the optical axis. The system controls the laser head to move toward the patient interface until the latter is centered on the optical axis.

9. 发明申请

WO2019033339A1 DISPOSABLE CONTACT LENS FOR OPTICAL TREATMENT SYSTEMS 审中-公开
公开(公告)号：WO2019033339A1
公开(公告)日：2019-02-21
申请号：PCT/CN2017/097856
申请日：2017-08-17
申请人： XINOVA, LLC , XIAO, Zhen
发明人： XIAO, Zhen
IPC分类号： A61F9/009
CPC分类号： A61F9/00821 , A61F9/009 , A61F2009/00844 , A61F2009/00863
摘要： A lens/sensor subassembly (318) may include a feedback sensor (324), a data transmission line (302), and an electrical element (328). The feedback sensor (324) may be configured to measure a phenomenon in an eye (100) of a patient during a laser-based ophthalmological therapy. The data transmission line (302) may be configured to communicate feedback data measured by the feedback sensor (324) to a laser-based ophthalmological treatment system (200). The electrical element (328) may be degradable in response to exposure to therapeutic radiation (316). The degradation of the electrical element (328) may interrupt communication of the feedback data measured by the feedback sensor (324) to the laser-based ophthalmological treatment system (200).

10. 发明申请

WO2018081645A1 PATIENT INTERFACE DEVICE FOR OPHTHALMIC SURGICAL LASER SYSTEM 审中-公开
标题翻译：用于眼科手术激光系统的患者接口装置
公开(公告)号：WO2018081645A1
公开(公告)日：2018-05-03
申请号：PCT/US2017/058877
申请日：2017-10-27
申请人： AMO DEVELOPMENT, LLC
发明人： GARCIA, Jose L. , ACCURSO, Roger W. , WONG, Daryl , WITOWSKI, Zenon
IPC分类号： A61F9/009
摘要： Apparatus and method for interfacing an ophthalmic surgical laser system with a patient's eye using a single-piece patient interface (PI). The PI includes a hollow shell, with an applanation lens and a flexible skirt at its lower end. Through channels are formed around the applanation lens to connect the spaces above and below the lens. When the PI is coupled to the laser system and the eye, the upper rim of the shell forms a seal with the laser system and the flexible skirt forms a seal with the eye. A vacuum is applied to the interior of the shell via a vacuum port on the laser system, and the vacuum is communicated to the space enclosed by the applanation lens, the skirt and the eye through the channels around the lens. A magnetic mechanism is also provided to hold the PI shell to the laser system.
摘要翻译：用于使用单件式患者接口（PI）将眼科手术激光系统与患者眼睛接合的设备和方法。该PI包括一个空心的外壳，在其下端有一个扁平透镜和一个柔软的裙子。在扁平透镜周围形成通道以连接透镜上方和下方的空间。当PI耦合到激光系统和眼睛时，外壳的上边缘与激光系统形成密封，并且柔性裙边与眼睛形成密封。通过激光系统上的真空端口将真空施加到壳体内部，并且通过透镜周围的通道将真空传送到由扁平透镜，裙部和眼睛所包围的空间。还提供了一个磁力机构来将PI外壳固定在激光系统上。

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