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1. 发明申请

WO2018192572A1 微生物及其用途审中-公开
公开(公告)号：WO2018192572A1
公开(公告)日：2018-10-25
申请号：PCT/CN2018/083951
申请日：2018-04-20
申请人：湖北广济药业股份有限公司
发明人：沈佳 , 郭韶智 , 洪果媛 , 曹金尹 , 黄实 , 高峰 , 黎艳华 , 陈志远
IPC分类号： C12N1/19 , C12P5/02 , C12R1/85
CPC分类号： C12P5/02 , C12R1/85
摘要：提供了一种微生物及其用途和利用该微生物获得番茄红素的方法，该微生物过表达包括选自tHMG1、BtCarG、PaCrtB、McCrtI、INO2、yap1、spt15-5、taf25-3、GapN、PYC2、SMAE1、MDH2、POS5、pntAB、ADH2、ACS6、ALD6、EUTE、ERG12、IDI1、ERG10、MVD1，ERG13、ERG8基因的至少之一；以及沉默包括选自GAL1、GAL7、GAL10、GAL80、ROX1、VBA5、DOS2、Ypl062W、Yjl064W、Yer130C、Yer134C、Ynr063W、Exg1、Yor292C、Sfk1、Mef1基因的至少之一。

2. 发明申请

WO2007099749A1 GENE ENCODING TREHALOSE-6-PHOSPHATE PHOSPHATASE AND USE THEREOF 审中-公开
标题翻译：基因编码TREHALOSE-6磷酸酯磷酸酶及其用途
公开(公告)号：WO2007099749A1
公开(公告)日：2007-09-07
申请号：PCT/JP2007/052167
申请日：2007-02-01
申请人： SUNTORY LIMITED , NAKAO, Yoshihiro , KODAMA, Yukiko , SHIMONAGA, Tomoko
发明人： NAKAO, Yoshihiro , KODAMA, Yukiko , SHIMONAGA, Tomoko
IPC分类号： C07K14/435 , C12Q1/42
CPC分类号： C12Q1/42 , C12C12/004 , C12C12/006 , C12G1/0203 , C12N9/16 , C12Q1/02 , C12R1/85 , C12Y301/03012 , G01N2333/39
摘要： The present invention relates to a gene encoding trehalose-6-phosphate phosphatase and use thereof, in particular, a yeast for practical use with superior resistance property to dryness and/or low-temperature storage, alcoholic beverages produced with said yeast, and a method for producing said beverages. More particularly, the present invention relates to a yeast, whose resistance property to dryness and/or resistance property to low-temperature storage is enhanced by amplifying expression level of TPS2 gene encoding a trehalose-6-phosphate phosphatase Tps2p in brewer's yeast, especially non-ScTPS2 gene specific to a lager brewing yeast and to a method for producing alcoholic beverages with said yeast, etc.
摘要翻译：本发明涉及编码海藻糖-6-磷酸磷酸酶的基因及其用途，特别是用于实际使用的具有优异的耐干性和/或低温储存性的酵母，用所述酵母生产的含酒精饮料的方法和方法用于生产所述饮料。更具体地说，本发明涉及通过扩增酿酒酵母中编码海藻糖-6-磷酸磷酸酶Tps2p的TPS2基因的表达水平，特别是非抑制性酵母，其酵母对抗低温贮藏的耐干性和/ 特异于啤酒酿造酵母的-ScTPS2基因和用酵母等生产酒精饮料的方法

3. 发明申请

WO2007046650A1 MICROORGANISMS HAVING BAD SMELL REMOVAL ACTIVITY OF ORGANIC WASTE AND USE THEREOF 审中-公开
标题翻译：有机废物微量去除活性微生物及其用途
公开(公告)号：WO2007046650A1
公开(公告)日：2007-04-26
申请号：PCT/KR2006/004270
申请日：2006-10-19
申请人： PARK, Se Joon
发明人： PARK, Se Joon
IPC分类号： C12N1/00 , C12N1/16 , C12N1/20
CPC分类号： C12R1/225 , A23K10/18 , A23L11/09 , A23L11/37 , A23L29/065 , C12R1/01 , C12R1/07 , C12R1/24 , C12R1/245 , C12R1/645 , C12R1/72 , C12R1/85
摘要： The present invention relates to novel microorganisms having the efficiency of removing an offensive odor from organic waste and the use thereof. More particularly, the novel microorganisms have the effects of preventing or removing the offensive odor from organic waste, killing insects and fungi, preventing decomposition, and promoting digestion and fermentation. The inventive microorganisms have the effects of preventing or removing the offensive odor from organic waste and killing noxious insects and plant pathogenic fungi, can be used as feed additives and antibiotic substitutes, and also are useful for the preparation of fermented healthy foods.
摘要翻译：本发明涉及具有从有机废物中除去令人反感的气味的效率的新型微生物及其用途。更具体地说，新型微生物具有防止或去除有机废物中的恶臭，杀死昆虫和真菌，防止分解，促进消化和发酵的效果。本发明的微生物具有防止或除去有机废物的恶臭，杀死有害昆虫和植物致病真菌的作用，可用作饲料添加剂和抗生素替代品，也可用于制备发酵的健康食品。

4. 发明申请

WO2010042896A1 NOVEL YEAST STRAIN AND METHODS OF USE THEREOF 审中-公开
标题翻译：新型YEAST菌株及其使用方法
公开(公告)号：WO2010042896A1
公开(公告)日：2010-04-15
申请号：PCT/US2009/060277
申请日：2009-10-09
申请人： FOSSIL FUELS BREWING COMPANY , CANO, Raul
发明人： CANO, Raul
IPC分类号： C12N1/18 , C12N15/00 , A23L1/28
CPC分类号： C12R1/85 , A21D8/047 , A23C9/127 , A23L2/52 , A23L33/14 , A23L33/145 , A23V2002/00 , C12C12/006 , C12G1/0203 , C12G3/02 , C12G3/12 , C12G2200/05 , A23V2200/08 , A23V2250/218 , A23V2200/3204
摘要： The present disclosure relates to an isolated yeast strain deposited as NRRL Y-50184. The present disclosure also relates generally to methods of manufacturing of products, including a fermented beverage or a fermented food using yeast cell from the isolated yeast strain or a cell culture derived from the strain.
摘要翻译：本公开涉及作为NRRL Y-50184沉积的分离的酵母菌株。本公开还涉及制造产品的方法，包括使用来自分离的酵母菌株的酵母细胞的发酵饮料或发酵食物或源自该菌株的细胞培养物。

5. 发明申请

WO2005066628A1 BIOLUMINESCENT ASSAYS AND CELLS USEFUL THEREIN 审中-公开
标题翻译：生物发光测定和细胞有用
公开(公告)号：WO2005066628A1
公开(公告)日：2005-07-21
申请号：PCT/IB2004/004124
申请日：2004-12-13
申请人： PFIZER PRODUCTS INC. , AUBRECHT, Jiri , OSOWSKI, Jeffery, John
发明人： AUBRECHT, Jiri , OSOWSKI, Jeffery, John
IPC分类号： G01N33/50
CPC分类号： G01N33/5017 , C12Q1/025 , C12R1/85 , G01N33/5008 , G01N33/502 , G01N33/5047
摘要： The present invention relates to novel bioluminescent assays and to cells and kits useful therein.
摘要翻译：本发明涉及新的生物发光测定法以及在其中有用的细胞和试剂盒。

6. 发明申请

WO03006648A2 NEW S. POMBE MUTANT STRAIN 审中-公开
标题翻译：新的POMBE突变菌株
公开(公告)号：WO03006648A2
公开(公告)日：2003-01-23
申请号：PCT/CA0201049
申请日：2002-07-09
申请人： UNIV MONTREAL , ROKEACH LUIS A
发明人： ROKEACH LUIS A
IPC分类号： C12N15/52 , C12N15/00
CPC分类号： C12R1/85 , C12N15/52
摘要： The present invention relates to a viable mutant strain of S . pombe having a non-calnexin protein-folding pathway activated to a level sufficient for expressing a protein in its functional three-dimensional structure, wherein the strain being viable without calnexin. It also relates to a method for identifying at least one gene involved in formation of prions, comprising the mutant strain of the present invention and to the use of the mutant strain of the present invention for overproducing recombinant proteins wherein the mutant strain being stably transformed to express a recombinant protein.
摘要翻译：本发明涉及一种活的可变突变菌株。具有活化到足以在其功能性三维结构中表达蛋白质的水平的非钙蛋白折叠途径的pombe ，其中所述菌株在没有钙蛋白的情况下是可行的。本发明还涉及用于鉴定至少一种参与朊病毒形成的基因的方法，其包含本发明的突变菌株和本发明的突变菌株用于过量产生重组蛋白质的用途，其中突变株稳定转化为表达重组蛋白。

7. 发明申请

WO1996010082A1 YEAST WITH MODIFIED PERMEABILITY 审中-公开
标题翻译： YEAST具有改性渗透性
公开(公告)号：WO1996010082A1
公开(公告)日：1996-04-04
申请号：PCT/FR1995001226
申请日：1995-09-22
申请人： RHONE-POULENC RORER S.A. , FLEER, Reinhard , MARCIREAU, Christophe , SCHERMAN, Daniel
发明人： RHONE-POULENC RORER S.A.
IPC分类号： C12N15/31
CPC分类号： C12R1/85 , C07K14/395 , C12N9/1007 , C12N15/81 , C12Q1/025
摘要： The present invention relates to a modified yeast wherein at least two of the genes controlling the cellular permeability of said yeast are modified, said modifications having an additive or synergic effect. It also relates to a method for the preparation of said yeast as well as to its utilizations.
摘要翻译：本发明涉及一种修饰的酵母，其中控制所述酵母的细胞通透性的基因中的至少两个被修饰，所述修饰具有添加剂或协同作用。它还涉及用于制备所述酵母以及其利用的方法。

8. 发明申请

WO1995020318A1 ANCIENT ORGANISMS 审中-公开
标题翻译：古代有机体
公开(公告)号：WO1995020318A1
公开(公告)日：1995-08-03
申请号：PCT/US1995001073
申请日：1995-01-27
申请人： AMBERGENE CORPORATION
发明人： AMBERGENE CORPORATION , CANO, Raul, J. , BORUCKI, Monica, K.
IPC分类号： A01N03/00
CPC分类号： C12R1/465 , C12N1/00 , C12R1/04 , C12R1/07 , C12R1/38 , C12R1/80 , C12R1/85 , G01N33/44
摘要： The recovery of live ancient bacteria, fungi and other biological material from various sources fossilized in amber or related resins is described. Several ancient bacterial strains have been classified as related to various species of the modern genus Bacillus, for example, based upon their morphological and biochemical characteristics, and enzymatic activity profiles. Although some of the characteristics of the ancient organisms correlate well with their modern counterparts, several differences have been observed. In addition, several of the ancient organisms described herein exhibit potent antimicrobial activities against modern bacterial and fungal pathogens which attack animals and plants. Various uses for these ancient organisms are envisioned, including their use in agriculture, industrial processes, bioremediation, diagnostic and disease treatment.
摘要翻译：描述了从琥珀色或相关树脂中化石的各种来源回收活的古代细菌，真菌和其他生物材料。已经将几种古代细菌菌株分类为与现代芽孢杆菌属的各种物种相关，例如，基于其形态和生物化学特征以及酶活性谱。虽然古代生物的一些特征与现代的相似物有很好的相关性，但是观察到一些差异。此外，本文所述的几种古代生物体对抗攻击动物和植物的现代细菌和真菌病原体表现出有效的抗微生物活性。预计这些古代生物的各种用途，包括其在农业，工业过程，生物修复，诊断和疾病治疗中的应用。

9. 发明申请

WO1992001064A1 MICROBIOLOGICAL METHOD FOR DETECTING MINERAL OR ORGANIC TOXIC PRODUCTS BY MEANS OF SACCHAROMYCES-TYPE YEAST STRAINS 审中-公开
标题翻译：微生物学方法用于检测矿物有机毒性物质
公开(公告)号：WO1992001064A1
公开(公告)日：1992-01-23
申请号：PCT/FR1991000544
申请日：1991-07-04
申请人： COMISSARIAT A L'ENERGIE ATOMIQUE , JACOB, François , PERRIER, Joseph , MOLEGNANA, Jacques , FAUGERAS, Pierre
发明人： COMISSARIAT A L'ENERGIE ATOMIQUE
IPC分类号： C12Q01/18
CPC分类号： C12R1/85 , C12Q1/02 , C12Q1/025
摘要： A microbiological method for detecting a mineral or organic toxic product, and the Saccharomyces strains which can be used for implementing the method, are described. According to the method, a vial (1) is used to grow microorganisms which are sensitive to the toxic product to be detected and can cause ethanol fermentation, such as Saccharomyces strains LyA1 Nr. I-964 and LyB1 Nr. I-965, using a culture medium containing the sample, whereafter the fermentation activity inhibition rate caused by the presence of the sample is determined, for example by measuring the quantities of CO2 given off (at 9) in the presence and absence of said sample.

10. 发明申请

WO1981000417A1 PROCESS FOR PREPARING PECTIN FROM VEGETABLE TISSUE 审中-公开
标题翻译：从蔬菜组织制备皮肤素的方法
公开(公告)号：WO1981000417A1
公开(公告)日：1981-02-19
申请号：PCT/JP1980000179
申请日：1980-08-08
申请人： SAKAI T , KATSURAGI T
IPC分类号： C12P19/04
CPC分类号： C08B37/0045 , C12R1/645 , C12R1/72 , C12R1/78 , C12R1/84 , C12R1/85 , C12R1/88 , Y10S435/911
摘要： A process for preparing pectin useful for foods, medicines, etc. by causing yeast to act on a pectin material-containing vegetable tissue such as pericarp of citrus said yeast having an activity of releasing pectin from vegetable tissue and belonging to the genus of Endomyces, Endomycopsis, Saccharomyces, Schizosaccharomyces, Pichia, Hansenula, Debaryomyces, Hanseniaspora, Tolulopsis, Candida, or Kluyveromyces, a culture medium thereof, or the treated product thereof.

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