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1. 发明申请

WO2014014490A1 ANTIMICROBIAL AGENTS 审中-公开
标题翻译：抗菌药物
公开(公告)号：WO2014014490A1
公开(公告)日：2014-01-23
申请号：PCT/US2013/000118
申请日：2013-04-30
申请人： BEDOUKIAN RESEARCH, INC. , BEDOUKIAN, Robert, H.
发明人： BEDOUKIAN, Robert, H.
IPC分类号： C12P7/26
CPC分类号： A01N35/06 , A01N31/06 , A01N37/02 , A23G4/06 , A23L3/34 , A23V2002/00 , C07C35/18 , C07C49/603
摘要： Compounds are used in compositions as antimicrobial agents against microbes, such as for example, Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Pseudomonas aeruginosa, Candida albicans, and Aspergillus brasiliensis. Antimicrobial action is obtained by contact of a microorganism with at least one of the compounds of the structure (I); wherein R is a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero or one double bond and a total of from 1 to 11 carbon atoms; R 1 is -OH, =0 or -OC(0)CH 3 and wherein the compounds of structure (I) contain a total of from 9 to 18 carbon atoms in the compounds.
摘要翻译：化合物在组合物中用作抗微生物剂，例如金黄色葡萄球菌，表皮葡萄球菌，大肠杆菌，铜绿假单胞菌，白色念珠菌和巴西曲霉。通过微生物与结构（I）的至少一种化合物的接触获得抗微生物作用; 其中R是具有0或1个双键和总共1至11个碳原子的支链或直链饱和或不饱和烃基; R 1是-OH，= 0或-OC（O）CH 3，并且其中结构（I）的化合物在化合物中含有总共9至18个碳原子。

2. 发明申请

WO2013165478A1 CONTROL AND REPELLENCY OF BED BUGS 审中-公开
标题翻译： BED BUGS的控制和回报
公开(公告)号：WO2013165478A1
公开(公告)日：2013-11-07
申请号：PCT/US2013/000122
申请日：2013-04-30
申请人： BEDOUKIAN RESEARCH, INC. , BEDOUKIAN, Robert, H.
发明人： BEDOUKIAN, Robert, H.
IPC分类号： A01N35/06
CPC分类号： C07C69/675 , A01N31/06 , A01N35/06 , A01N37/02 , A01N37/18 , A01N37/22 , A01N37/36 , A01N37/42 , A01N43/08 , A01N43/16 , A01N49/00 , C07C35/06 , C07C35/18 , C07C59/205 , C07C69/708 , C07C235/74 , C07C2601/08 , C07C2601/16 , C07D307/33 , C07D309/30 , A01N2300/00
摘要： Control or repellency of bed bugs is accomplished by bringing the bed bugs into contact with at least one of the compounds of the structure (I); wherein R is selected from -OH, -OC(O)R 4 , -OR 6 , -(OR 6 ) 2 , wherein each R 6 is independently selected from an alkyl group containing from 1 to 4 carbon atoms and R 4 is a branched or straight chain saturated or unsaturated hydrocarbyl group with zero to two double bonds and from 1 to 15 carbon atoms; X is O or CH 2 , with the proviso that when X is O R can only be =0; each Z is independently selected from (CH) and (CH 2 ) y is a numeral selected from 1 and 2; R 1 is selected from H or a branched or straight chain saturated or unsaturated hydrocarbyl group with zero to two double bonds and from 1 to 15 carbon atoms. R 2 is selected from H and a branched or straight chain saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 15 carbon atoms. R 3 is selected from H, a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 15 carbon atoms, -(CH 2 ) n OH, -C(O)OR 5 , -CH 2 C(O)OR 7 , - CH 2 C(O)R 8 , -C(O)NR 9 R 10 , -CH 2 C(O)NR 11 R 12 where each of R 5 , R 7 , R 8 , R 9 , R 10 , R 11 and R 12 is independently selected from H and a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 15 carbon atoms, and n is an integer of from 1 to 12; and the bond between the 2 and 3 positions in the ring structure may be a single or a double bond, and wherein the compounds of structure (1) contain from 11 to 20 total carbon atoms, except where R is =O, X = CH 2 and y is 1 the compounds of structure (I) contain from 13 to 20 total carbon atoms in the compounds, wherein the compounds of structure (1) contain from 1 1 to 20 total carbon atoms, except where R is =O, X = CH2 and y is 1 the compounds of structure (I) contain from 13 to 20 total carbon atoms in the compounds, wherein the compounds of structure (1) contain from 11 to 20 total carbon atoms, except where R is =0, X = CH 2 and y is 1 the compounds of structure (I) contain from 13 to 20 total carbon atoms in the compounds.
摘要翻译：通过使床臭虫与至少一种结构（I）的化合物接触来实现臭虫的控制或排斥; 其中R选自-OH，-OC（O）R 4，-OR 6， - （OR 6）2，其中每个R 6独立地选自含有1至4个碳原子的烷基，R 4是支链或直链饱和或具有0至2个双键和1至15个碳原子的不饱和烃基; X是O或CH2，条件是当X是O时，R只能是= 0; 每个Z独立地选自（CH）和（CH 2）y是选自1和2的数字; R1选自H或具有0至2个双键和1至15个碳原子的支链或直链饱和或不饱和烃基。 R2选自H和具有0至3个双键和1至15个碳原子的支链或直链饱和或不饱和烃基。 R 3选自H，具有0至3个双键和1至15个碳原子的支链或直链饱和或不饱和烃基， - （CH 2）n OH，-C（O）OR 5，-CH 2 C（O）OR 7 ， - CH 2 C（O）R 8，-C（O）NR 9 R 10，-CH 2 C（O）NR 11 R 12，其中R 5，R 7，R 8，R 9，R 10，R 11和R 12各自独立地选自H和支链或直链饱和或具有0至3个双键和1至15个碳原子的不饱和烃基，n为1至12的整数; 并且环结构中2和3位之间的键可以是单键或双键，并且其中结构（1）的化合物含有11至20个总碳原子，除了R是= O，X = CH 2 并且y为1，化合物中结构（I）的化合物含有13至20个总碳原子，其中结构（1）的化合物含有11至20个总碳原子，除了R为=，X = CH2和y为1，化合物中结构（I）的化合物含有13至20个总碳原子，其中结构式（1）的化合物含有11至20个总碳原子，除了R为= 0，X = CH2和y为1，化合物中结构（I）的化合物含有13至20个总碳原子。

3. 发明申请

WO2011093742A8 AGENT FOR TREATING PARKINSON'S DISEASE 审中-公开
标题翻译：治疗帕金森病的药剂
公开(公告)号：WO2011093742A8
公开(公告)日：2012-11-22
申请号：PCT/RU2010000778
申请日：2010-12-23
申请人： OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOSTYU TOM FARMATSEVTICHESKAYA FABRIKA OOO TFF , SALAHUTDINOV NARIMAN FARIDOVICH , TOLSTIKOVA TATIANA GENRIHOVNA , PAVLOVA ANASTASIA VIKTOROVNA , MOROZOVA EKATERINA ALEKSANDROVNA , IL INA IRINA VIKTOROVNA , ARDASHOV OLEG VASIL EVICH , VOLCHO KONSTANTIN PETROVICH
发明人： SALAHUTDINOV NARIMAN FARIDOVICH , TOLSTIKOVA TATIANA GENRIHOVNA , PAVLOVA ANASTASIA VIKTOROVNA , MOROZOVA EKATERINA ALEKSANDROVNA , IL INA IRINA VIKTOROVNA , ARDASHOV OLEG VASIL EVICH , VOLCHO KONSTANTIN PETROVICH
IPC分类号： A61K31/015 , A61K31/047 , A61K31/215 , A61P25/16
CPC分类号： C07C35/18 , A61K31/015 , A61K31/047 , A61K31/215 , C07C69/96
摘要： The invention relates to the use of 3-methyl-6-(1-methylethenyl)cyclohex-3-ene-1,2-diol and isomers and derivatives thereof as an agent for treating Parkinson's disease, and can be used in the field of medicine. The agent has high activity and low toxicity and can be produced from the accessible naturally occurring compound a-pinene.
摘要翻译：本发明涉及3-甲基-6-（1-甲基乙烯基）环己-3-烯-1,2-二醇及其异构体和衍生物作为治疗帕金森病的药物的用途，可用于医学。该试剂具有高活性和低毒性，可由可及的天然化合物α-蒎烯生产。

4. 发明申请

WO2010061350A1 HYDROGENATION OF ESTER, KETONE OR ALDEHYDE GROUPS WITH RUTHENIUM COMPLEXES HAVING A DI-AMINE AND A PHOSPHOROUS-NITROGEN BIDENTATE LIGAND 审中-公开
标题翻译：含有二胺和磷酸二氢铵配位体的钌络合物的酯，酮或醛组合物的加氢反应
公开(公告)号：WO2010061350A1
公开(公告)日：2010-06-03
申请号：PCT/IB2009055368
申请日：2009-11-26
申请人： FIRMENICH & CIE , SAUDAN LIONEL , SAUDAN MICHEL ALFRED JOSEPH , SAUDAN SYLVIA JOYEUSE ADELAIDE
发明人： SAUDAN LIONEL , SAUDAN CHRISTOPHE
IPC分类号： B01J31/18 , B01J31/22 , C07C29/136 , C07C29/145
CPC分类号： B01J31/1805 , B01J31/1815 , B01J31/182 , B01J31/189 , B01J31/2295 , B01J2531/0216 , B01J2531/0263 , B01J2531/0266 , B01J2531/821 , C07C29/141 , C07C29/145 , C07C29/149 , C07C403/08 , C07C2601/02 , C07C2601/08 , C07C2601/10 , C07C2601/14 , C07C2601/16 , C07C2602/10 , C07C33/22 , C07C33/32 , C07C33/20 , C07C35/21 , C07C33/12 , C07C33/34 , C07C33/14 , C07C31/125 , C07C35/08 , C07C35/18 , C07C31/1333
摘要： The present invention relates to the field of catalytic hydrogenation and, more particularly, to the use of specific ruthenium catalysts, or pre-catalysts, in hydrogenation processes with molecular H2 for the reduction of ketones, aldehydes and esters or lactones into the corresponding alcohol or diol respectively. Said catalysts are ruthenium complexes comprising a ligand of the type (N-N) type, in which at least one of said amino groups is a secondary or primary amine (i.e. a NH or NH2) and a ligand of the type (P-N) in which N belongs to a tertiary amino group, a N, N, N' trisubstituted carboxiamide (a C(=N)N moiety) or a N-substituted imidoate (a C(=N)O moiety).
摘要翻译：本发明涉及催化氢化领域，更具体地说，涉及在具有分子H 2的氢化方法中使用特定的钌催化剂或预催化剂以将酮，醛和酯或内酯还原成相应的醇或二醇。所述催化剂是包含类型（NN）型配体的钌络合物，其中至少一个所述氨基是仲胺或伯胺（即NH或NH 2）和其中N（N）型的配体，其中N 属于叔氨基，N，N，N'三取代羧酰胺（C（= N）N部分）或N-取代亚氨酸酯（C（= N）O部分））。

5. 发明申请

WO2008091686A3 SYNTHESIS OF 1a-FLUORO-25-HYDROXY-16-23E-DIENE-26,27-BISHOMO-20-EPI-CHOLECALCIFEROL 审中-公开
标题翻译： 1α-氟-25-羟基-16-23E-二烯-26,27-二肉豆蔻-20-烯-D-胆甾醇的合成
公开(公告)号：WO2008091686A3
公开(公告)日：2008-10-09
申请号：PCT/US2008000970
申请日：2008-01-25
申请人： BIOXELL SPA , MAEHR HUBERT , USKOKOVIC MILAN R
发明人： MAEHR HUBERT , USKOKOVIC MILAN R
IPC分类号： A61K31/59 , C07C401/00 , C07C403/00
CPC分类号： C07C401/00 , C07B2200/07 , C07C29/48 , C07C45/516 , C07C67/08 , C07C67/29 , C07C67/293 , C07C67/297 , C07C67/343 , C07C69/013 , C07C69/732 , C07C309/73 , C07C2601/16 , C07C2602/24 , C07C2602/28 , C07C35/32 , C07C35/18 , C07C47/267 , C07C69/16 , C07C69/14 , C07C69/145
摘要： The invention provides a method of producing 20-methyl vitamin D 3 compounds of formula (I). The method includes hydroxylation, carbonyl reduction, fluoride substitution, epoxide deoxygenation, and Wittig-type couplings.
摘要翻译：本发明提供了制备式（I）的20-甲基维生素D 3化合物的方法。该方法包括羟基化，羰基还原，氟化物取代，环氧化物脱氧和Wittig型偶联。

6. 发明申请

WO2005112915A3 DECREASE IN OXIDATIVE STRESS STATUS THROUGH THE ADMINISTRATION OF NATURAL PRODUCTS AND PHARMACEUTICAL DRUGS 审中-公开
标题翻译：通过天然产物和药物药物的管理减少氧化应激状态
公开(公告)号：WO2005112915A3
公开(公告)日：2006-03-16
申请号：PCT/US2005019018
申请日：2005-05-20
申请人： EXETER LIFE SCIENCES , CUTLER RICHARD G
发明人： CUTLER RICHARD G
IPC分类号： A61K31/353 , A61K31/375 , C07C31/125 , C07C33/02 , C07C35/18 , C07C331/22 , A61K31/35 , A61K31/075 , A61K31/115 , A61K31/12 , A61K31/19 , C07C9/00 , C07C27/10 , C07C49/04 , C07C69/00 , C07C205/00 , C07D311/04 , C07D315/00
CPC分类号： C07C11/21 , C07C13/20 , C07C31/125 , C07C33/02 , C07C35/18 , C07C49/203 , C07C49/255 , C07C50/14 , C07C50/28 , C07C59/42 , C07C331/22 , C07C403/02 , C07C403/12 , C07C2601/16 , C07D311/72 , C07H15/10 , C07H15/24 , C07J9/00
摘要： The present invention provides compositions, methods, and kits for reducing oxidative stress thereby extending life span. The compositions, methods, and kits of the present invention can also be used to treat diseases of aging resulting from oxidative stress.
摘要翻译：本发明提供用于减少氧化应激从而延长使用寿命的组合物，方法和试剂盒。本发明的组合物，方法和试剂盒也可用于治疗由氧化应激引起的老化疾病。

7. 发明申请

WO2004096740A3 PROCESS FOR PREPARATION OF (+)-P-MENTHA-2,8-DIENE-1-OL 审中-公开
标题翻译：（+） - 对 - 戊二烯-2,8-二烯-1-醇的制备方法
公开(公告)号：WO2004096740A3
公开(公告)日：2005-06-02
申请号：PCT/US2004011509
申请日：2004-04-14
申请人： MALLINCKRODT INC , GU HONG , KILLGORE J KENDALL , DUCHEK JOHN R
发明人： GU HONG , KILLGORE J KENDALL , DUCHEK JOHN R
IPC分类号： C07C29/00 , C07C213/04 , C07C215/44 , C07C291/04 , C07C29/10 , C07C29/74
CPC分类号： C07D295/096 , C07C29/00 , C07C213/04 , C07C291/04 , C07C2601/14 , C07C2601/16 , C07C215/44 , C07C35/18
摘要： A process for preparing (+)-p-mentha-2,8-diene-1-ol comprising reacting (+)-limonene oxide with at least one amine in the presence of at least one Lewis acid to form amine adduct intermediates. The amine adduct is then oxidized to form an N-oxide that is pyrolized to form (+)-p-mentha-2,8-diene-1-ol.
摘要翻译：制备（+） - 对 - 薄荷-2,8-二烯-1-醇的方法包括在至少一种路易斯酸存在下使（+） - 柠檬烯氧化物与至少一种胺反应形成胺加合物中间体。然后将胺加合物氧化以形成N-氧化物，其被热解形成（+） - 对 - 薄荷-2,8-二烯-1-醇。

8. 发明申请

WO02046131A1 SUBSTITUTED CYCLOHEXENES 审中-公开
标题翻译：取代环己烷
公开(公告)号：WO02046131A1
公开(公告)日：2002-06-13
申请号：PCT/EP2001/014107
申请日：2001-12-03
IPC分类号： A23L27/20 , C07B61/00 , C07C35/18 , C07C43/188 , C07C45/00 , C07C49/647 , C07C49/653 , C07C49/683 , C07C403/02 , C11B9/00
CPC分类号： C11B9/0049 , C07C35/18 , C07C43/188 , C07C49/653 , C07C49/683 , C07C403/02 , C07C2601/16 , C11B9/0034
摘要： The present invention relates to substituted cyclohexenes, to their use as well as to their preparation method. These compounds have powerful long lasting natural fruity grapefruit notes with minty and fresh green tonalities.
摘要翻译：本发明涉及取代的环己烯，其用途及其制备方法。这些化合物具有强力的持久的天然水果葡萄柚笔记，具有鲜而鲜的绿色色调。

9. 发明申请

WO00023186A1 TITANIUM SILICATE MOLECULAR SIEVE OXIDATION CATALYSTS AND THE PRODUCTION THEREOF 审中-公开
标题翻译：硅酸铈分子筛氧化催化剂及其生产
公开(公告)号：WO00023186A1
公开(公告)日：2000-04-27
申请号：PCT/US1999/023784
申请日：1999-10-13
IPC分类号： B01J29/89 , C01B39/08 , C07C29/48 , C01B39/02
CPC分类号： C01B39/085 , B01J29/89 , C07C29/48 , C07C2601/14 , C07C2601/16 , C07C35/18 , C07C35/14 , C07C31/20
摘要： Disclosed are novel crystalline molecular sieves having the framework of ETS-10 titanium silicate which contain both octahedral and tetrahedral titanium atoms and are in acid form. The sieves are prepared by adding a complexing agent such as hydrogen peroxide during synthesis or by treating a synthesized titanium silicate molecular sieve with a reagent that replaces tetrahedral silicon with tetrahedral titanium atoms.
摘要翻译：公开了具有含有八面体和四面体钛原子并呈酸性形式的ETS-10钛硅酸盐骨架的新型结晶分子筛。通过在合成过程中加入络合剂如过氧化氢或通过用四取代硅原子代替四面体硅的试剂处理合成的硅酸钛分子筛来制备筛子。

10. 发明申请

WO2016202925A1 HYDROGENATION OF ALDEHYDE OR KETONE COMPOUNDS WITH FE/TRIDENTATE LIGANDS COMPLEXES 审中-公开
标题翻译：用有机/三态配体复合物氢化醛或酮酮化合物
公开(公告)号：WO2016202925A1
公开(公告)日：2016-12-22
申请号：PCT/EP2016/063893
申请日：2016-06-16
申请人： FIRMENICH SA
发明人： SAUDAN, Lionel , PRAZ, Jézabel
IPC分类号： C07C29/141 , C07C29/145 , B01J31/18
CPC分类号： C07C29/145 , B01J31/189 , B01J31/20 , B01J31/2208 , B01J31/2226 , B01J31/24 , B01J2231/643 , B01J2531/842 , C07C29/141 , C07C2601/10 , C07C2601/14 , C07C2601/16 , C07F15/02 , C07C33/22 , C07C35/08 , C07C35/18 , C07C35/06 , C07C33/30 , C07C33/20 , C07C33/14 , C07C31/125 , C07C33/32
摘要： The present invention relates to the field of catalytic hydrogenation and, more particularly, to the use of Fe complexes with tridentate ligands, having one amino or imino coordinating group and two phosphino coordinating groups, in hydrogenation processes for the reduction of ketones or aldehydes, into the corresponding alcohol or diol, respectively.
摘要翻译：本发明涉及催化氢化领域，更具体地说，涉及在用于还原酮或醛的氢化方法中使用具有一个氨基或亚氨基配位基团和三个配位基团的三齿配体的Fe络合物相应的醇或二醇。

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