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1. 发明申请

WO2017023206A1 DEVICE FOR INSERTION INTO A BODY CAVITY, AND METHOD OF FABRICATION THEREOF 审中-公开
标题翻译：用于插入身体穴位的装置及其制造方法
公开(公告)号：WO2017023206A1
公开(公告)日：2017-02-09
申请号：PCT/SG2016/050371
申请日：2016-07-29
申请人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , NATIONAL UNIVERSITY HOSPITAL (SINGAPORE) PTE LTD , SINGAPORE HEALTH SERVICES PTE LTD
发明人： M SINA RAJA, Prusothman , DHARMAWAN, Angela Renayanti , TEE, Chee Keong , WANG, Yao , LIM, Sheau Huei Frances , CHONG, Zhengtao Keith
IPC分类号： A61F7/12 , A61M31/00
CPC分类号： A61F7/123 , A61F7/106 , A61F7/12 , A61F2007/0091 , A61F2007/0092 , A61F2007/0258 , A61F2007/0261 , A61F2007/0276 , A61F2007/101 , A61M31/00
摘要： There is provided a device for insertion into a body cavity, the device includes an insertion member configured to be inserted into the body cavity, an expandable member coupled to the insertion member, the expandable member capable of being expanded to apply pressure onto tissue within the body cavity, a first member configured for storing a first endothermic reactant therein, and a second member configured for storing a second endothermic reactant therein. In particular, the first and second members are configured to, in a state of the device (e.g., compressed state), allow the first and second endothermic reactants to cooperate to effect an endothermic reaction to generate an endothermic product. Furthermore, the expandable member is configured to receive at least one of the first or second endothermic reactant and the endothermic product through a channel within the insertion member. There is also provided a method of fabricating a device for inserting into a body cavity.
摘要翻译：提供了一种用于插入体腔的装置，该装置包括构造成插入到体腔中的插入构件，与插入构件联接的可扩张构件，该可膨胀构件能够被膨胀以向该内腔内的组织施加压力体腔，构造成用于在其中存储第一吸热反应物的第一构件和被配置为在其中存储第二吸热反应物的第二构件。特别地，第一和第二构件被构造成在装置的状态（例如，压缩状态）下，允许第一和第二吸热反应物协同作用以产生吸热产物的吸热反应。此外，可膨胀构件构造成通过插入构件内的通道容纳第一或第二吸热反应物和吸热产品中的至少一个。还提供了一种制造用于插入体腔的装置的方法。

2. 发明申请

WO2013122349A1 배액 기능을 겸비한 개두 수술 환자용 뇌 냉각 장치 审中-公开
标题翻译：脑冷却装置也具有流体排放功能
公开(公告)号：WO2013122349A1
公开(公告)日：2013-08-22
申请号：PCT/KR2013/000957
申请日：2013-02-06
申请人： 경북대학교 산학협력단
发明人： 박재찬 , 석경호 , 한형수 , 이동익
IPC分类号： A61B18/02 , A61M1/00 , A61M27/00
CPC分类号： A61F7/12 , A61F7/10 , A61F2007/0002 , A61F2007/0056 , A61F2007/0095 , A61F2007/101 , A61F2007/126 , A61M27/00 , A61M27/002 , A61M2027/004
摘要： 본 발명의 일 실시예에 따른 뇌 냉각장치는 온도센서는 냉각유체이송관의 일단과 타단에 각각 설치되어 온도를 센싱하며, 저장탱크에는 압력측정센서가 설치되고, 온도센서와 압력측정센서에는 제어부가 연결되어 제어부는 저장탱크의 압력변화 및 온도센서에서 센싱된 온도에 따라 뇌로부터 흡열된 열량을 계산하는 것이 바람직하다. 본 발명의 일 실시예에 따른 뇌 냉각장치의 냉각유체이송관과 배액관은 일측이 절곡되어 인접한 배액관 사이가 밀착되는 것이 바람직하다. 본 발명에 따른 뇌 냉각장치는 뇌 경막 또는 절개된 뇌 경막 수술이 실시된 부위에 직접 설치하여 효과적으로 열 또는 붓기를 완화시키고 사용이 끝난 후 냉각유체를 유출입시키는 두피와 두개골을 관통한 수술구멍을 통하여 뇌 냉각장치를 제거할 수 있도록 함으로써 별도의 수술 없이 제거할 수 있는 효과가 있으며, 기화된 액체질소 등을 냉각유체로 사용함으로써 별도의 기계, 전기적 설비를 구비하지 않고 뇌를 냉각시킬 수 있는 효과가 있다. 아울러 냉각장치에 설치된 드레인 홀을 이용하여 수술부위에 고여있는 혈액 등을 배출시킬 수 있는 효과가 있다.
摘要翻译：根据本发明的一个实施例的脑冷却装置理想地包括：温度传感器，其分别安装在用于感测温度的冷却流体输送管的一端和另一端; 安装在储罐上的压力测量传感器; 以及控制部分，其连接到温度传感器和压力测量传感器，用于计算从储存罐中的压力变化和由温度传感器感测的温度从大脑吸收的热量。根据本发明的脑冷却装置的冷却液输送管和放电管在一侧弯曲，使得相邻的放电管彼此紧密接触。根据本发明的脑冷却装置直接安装在硬脑膜或在已经进行硬脑膜手术的区域上，从而有效地减轻热量或肿胀，可以通过手术孔被有效地去除，穿孔通过头皮和颅骨，并且允许冷却液通过，而不需要额外的手术，并且可以通过使用气化液氮或类似物作为冷却流体而有效地冷却大脑而不需要单独的机械或电气设备。此外，本发明可以通过使用设置在冷却装置上的排水孔来有效地排出收集在手术区域中的血液或类似物。

3. 发明申请

WO2007142571A8 HIGH VISCOSITY COMPOSITION 审中-公开
标题翻译：高粘度组合物
公开(公告)号：WO2007142571A8
公开(公告)日：2008-05-08
申请号：PCT/SE2007000504
申请日：2007-05-25
申请人： BECARE ORTHOPEDIC THERMAL CARE , HOEGLUND CHRISTER , KRYZANIAK DAG
发明人： HOEGLUND CHRISTER , KRYZANIAK DAG
IPC分类号： C08L71/02 , A61F7/02 , A61F7/08 , A61F7/10
CPC分类号： A61F7/02 , A61F2007/0001 , A61F2007/101 , C08L1/00 , C08L39/06 , C08L71/02 , C08L2666/04
摘要： A high viscosity composition which according to the invention comprises at least one polyoxyethylene- -polyoxypropylene-block copolymer (poloxamer) having the structural formula HO(C 2 H 4 O) a (C 3 H 6 O) b (C 2 H 4 O) a H and having an average molecular weight of above 6000; at least one additional polymer having an average molecular weight of above 150000, and a dispersion medium, comprising at least one freezing point depressing dispersant and at least one freezing point non-depressing dispersant. The composition is heatable above the body temperature of a mammal and coolable below 0°C within a predetermined temperature range.
摘要翻译：根据本发明的高粘度组合物包含至少一种具有结构式HO（C 2 H 4 O）的聚氧乙烯 - 聚氧丙烯嵌段共聚物（泊洛沙姆）（C 3 H 6）（C 3 H 6）（C 3 H 6） 4 O）a H平均分子量高于6000; 至少一种平均分子量高于150000的另外的聚合物，和包含至少一种降冰块分散剂和至少一种凝固点非抑制分散剂的分散介质。该组合物可以在哺乳动物体温之上加热并在预定温度范围内在0℃以下可冷却。

4. 发明申请

WO2005018433A2 CONFORMAL PAD FOR NEUROSURGERY AND METHOD THEREOF 审中-公开
标题翻译：用于神经外科的一致性垫片及其方法
公开(公告)号：WO2005018433A2
公开(公告)日：2005-03-03
申请号：PCT/US2004/027254
申请日：2004-08-23
申请人： SEACOAST TECHNOLOGIES, INC.
发明人： LARNARD, Donald, J. , ROBINSON, Timothy, W.
IPC分类号： A61B
CPC分类号： A61F7/123 , A61B2017/00084 , A61B2090/064 , A61F2007/0056 , A61F2007/0075 , A61F2007/101 , A61F2007/126
摘要： A medical device and method for thermally affecting tissue are provided. The device includes a fluid inlet conduit a fluid outlet conduit and a shapeable body operatively connected to the fluid inlet and the fluid outlet conduit. The shapeable body defines a tissue contact region and the shapeable body has a height, a length, and a width in which the height is less than the length and the width. The shapeable body further includes a first channel and a second channel which are substantially parallel from the proximal end of the shapeable body to the distal end of the shapeable body and which are in fluid communication. The shapeable body further has a malleable conformation such that the body retains a first shape until manipulated to a second shape.
摘要翻译：提供了一种用于热影响组织的医疗装置和方法。该装置包括流体入口导管，流体出口导管和可操作地连接到流体入口和流体出口导管的可成形体。可成形体限定了组织接触区域，并且可塑体具有高度，长度和宽度，其中高度小于长度和宽度。可成形体还包括第一通道和第二通道，第一通道和第二通道基本上平行于可成型体的近端到可成形体的远端，并且与第二通道流体连通。可成形体还具有可延展构造，使得主体保持第一形状，直到被操纵为第二形状。

5. 发明申请

WO1997027799A1 LESS-INVASIVE DEVICES AND METHODS FOR CARDIAC VALVE SURGERY 审中-公开
标题翻译：用于心脏瓣膜手术的无缺陷装置和方法
公开(公告)号：WO1997027799A1
公开(公告)日：1997-08-07
申请号：PCT/US1997001018
申请日：1997-01-23
申请人： HEARTPORT, INC.
发明人： HEARTPORT, INC. , DONLON, Brian, S. , PETERS, William, S. , GARRISON, Michi, E. , ROSENMAN, Daniel, C. , STEVENS, John, H.
IPC分类号： A61B05/00
CPC分类号： A61B17/00234 , A61B17/0057 , A61B17/0218 , A61B17/0293 , A61B17/0467 , A61B17/0469 , A61B17/06061 , A61B17/122 , A61B17/29 , A61B17/2909 , A61B17/3417 , A61B17/3421 , A61B18/1492 , A61B90/36 , A61B90/50 , A61B2017/00053 , A61B2017/00243 , A61B2017/00247 , A61B2017/00278 , A61B2017/00575 , A61B2017/00867 , A61B2017/00907 , A61B2017/00946 , A61B2017/0237 , A61B2017/0243 , A61B2017/047 , A61B2017/0472 , A61B2017/0474 , A61B2017/0475 , A61B2017/0496 , A61B2017/2912 , A61B2017/2926 , A61B2017/2927 , A61B2017/2932 , A61B2017/2943 , A61B2017/306 , A61B2017/308 , A61B2017/3405 , A61B2017/3492 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00291 , A61B2018/00363 , A61B2018/00392 , A61B2018/00577 , A61B2018/00982 , A61B2090/061 , A61B2090/306 , A61F2/2427 , A61F2/2496 , A61F7/10 , A61F2007/0001 , A61F2007/0054 , A61F2007/101 , A61M1/3621 , A61M25/1011 , A61M39/0247 , A61M2025/028 , A61M2039/027 , A61M2039/0279 , A61M2202/047 , A61M2205/3344 , A61M2205/3355 , A61M2205/366 , Y10S623/902
摘要： Systems and methods are disclosed for performing less invasive surgical procedures within the heart. A method for less invasive repair or replacement of a cardiac valve (216) comprises placing an instrument (290) through an intercostal access port (212) and through a penetration in a wall of a vessel in communication with the heart, advancing the instrument (290) into the heart, using the instrument (290) to perform a surgical intervention on a cardiac valve (216) in the heart under visualization through an intercostal access port. The surgeons hands are kept outside of the chest during each step. The surgical intervention may comprise replacing the cardiac valve with a prosthetic valve, wherein the native valve is removed using a tissue removal instrument (206), the native valve annulus is sized with a specialized sizing device (216), a prosthetic valve is introduced through an intercostal access port (212) and through the penetration in the vessel, and the prosthetic valve is secured at the native valve position, all using instruments positioned through intercostal access ports without placing the hands inside the chest. Systems and devices for performing these procedures are also disclosed.
摘要翻译：公开了用于在心脏内执行较少侵入性外科手术的系统和方法。用于较少侵入性修复或更换心脏瓣膜（216）的方法包括将器械（290）穿过肋间进入口（212）并通过与心脏连通的血管壁穿透，推进器械 290）进入心脏，使用仪器（290）通过肋间进入端口在可视化的心脏内的心脏瓣膜（216）上执行手术干预。在每一步中，外科医生的手都保持在胸前。外科手术可以包括用假性瓣膜替换心脏瓣膜，其中使用组织去除器具（206）去除所述天然瓣膜，所述天然瓣膜通过专门的上浆装置（216）来定尺寸，通过引入人工瓣膜肋间进入口（212），并穿过容器内的穿透，并且人造瓣膜固定在天然瓣膜位置，所有这些都使用通过肋间进入口定位的器械，而不将手放在胸部内。还公开了用于执行这些程序的系统和装置。

6. 发明申请

WO2007078328A2 LIQUID ABSORBING COOLING PAD 审中-公开
标题翻译：液体吸收冷却垫
公开(公告)号：WO2007078328A2
公开(公告)日：2007-07-12
申请号：PCT/US2006029147
申请日：2006-07-28
申请人： LEE JANET ARMSTRONG , LEE ROBERT EUGENE
发明人： LEE JANET ARMSTRONG , LEE ROBERT EUGENE
IPC分类号： A61F13/15
CPC分类号： A61F13/84 , A61F2007/0098 , A61F2007/0292 , A61F2007/101
摘要： An article for absorbing fluid from the perineum of a woman and simultaneously cooling the perineum. The article comprises two regions, said regions being a front region that contacts the woman's body over at least a portion of its surface, a rear region and an optional central fluid impermeable partition disposed between the front region and the rear region. A pocket between the regions contains a cooling medium.
摘要翻译：一种吸收女性会阴液体并同时冷却会阴的物品。该物品包括两个区域，所述区域是在其表面的至少一部分上接触女性身体的前部区域，后部区域以及布置在前部区域和后部区域之间的可选中央流体不可渗透的隔离物。区域之间的口袋包含冷却介质。

7. 发明申请

WO2006033655A1 INFLATABLE DEVICE FOR TREATING TISSUE 审中-公开
标题翻译：用于治疗组织的可充电装置
公开(公告)号：WO2006033655A1
公开(公告)日：2006-03-30
申请号：PCT/US2004/020005
申请日：2004-06-22
申请人： SEACOAST TECHNOLOGIES, INC.
发明人： LARNARD, Donald, J.
IPC分类号： A61M31/00
CPC分类号： A61F7/123 , A61B2017/00084 , A61F2007/0056 , A61F2007/0075 , A61F2007/101 , A61F2007/126
摘要： A method and expandable device for thermally affecting tissue in which there is a fluid conduit. The device including a housing having a first end region and a second end region, the second end region containing a fluid inlet and a fluid outlet, the housing being securable to a boney structure of the patient. An expandable element, including a wall defining an inner volume and a tissue contacting surface, is coupled to the housing first end region such that the inner volume is in fluid communication with the fluid inlet and the fluid outlet.
摘要翻译：一种用于热影响组织的方法和可扩张装置，其中存在流体导管。所述装置包括具有第一端区域和第二端区域的壳体，所述第二端区域包含流体入口和流体出口，所述壳体可固定到患者的骨盆结构。包括限定内部体积和组织接触表面的壁的可膨胀元件联接到壳体第一端部区域，使得内部容积与流体入口和流体出口流体连通。

8. 发明申请

WO2005018433A3 CONFORMAL PAD FOR NEUROSURGERY AND METHOD THEREOF 审中-公开
标题翻译：用于神经外科手术的一种护垫及其方法
公开(公告)号：WO2005018433A3
公开(公告)日：2005-12-29
申请号：PCT/US2004027254
申请日：2004-08-23
申请人： SEACOAST TECHNOLOGIES INC
发明人： LARNARD DONALD J , ROBINSON TIMOTHY W
IPC分类号： A61B20060101 , A61B17/00 , A61B19/00 , A61F7/00 , A61F7/10 , A61F7/12
CPC分类号： A61F7/123 , A61B2017/00084 , A61B2090/064 , A61F2007/0056 , A61F2007/0075 , A61F2007/101 , A61F2007/126
摘要： A medical device and method for thermally affecting tissue are provided. The device includes a fluid inlet conduit a fluid outlet conduit and a shapeable body operatively connected to the fluid inlet and the fluid outlet conduit. The shapeable body defines a tissue contact region and the shapeable body has a height, a length, and a width in which the height is less than the length and the width. The shapeable body further includes a first channel and a second channel which are substantially parallel from the proximal end of the shapeable body to the distal end of the shapeable body and which are in fluid communication. The shapeable body further has a malleable conformation such that the body retains a first shape until manipulated to a second shape.
摘要翻译：提供了一种用于热影响组织的医疗装置和方法。该装置包括流体入口导管，流体出口导管和可操作地连接到流体入口和流体出口导管的可成形主体。可成形主体限定组织接触区域，并且可成形主体具有高度，长度和宽度，其中高度小于长度和宽度。所述可变形主体还包括第一通道和第二通道，所述第一通道和第二通道从所述可变形主体的所述近端到所述可变形主体的所述远端基本平行，并且所述第一通道和所述第二通道流体连通。可塑形主体还具有可延展的构造，使得主体保持第一形状，直到被操纵为第二形状。

9. 发明申请

WO2003084408A1 COOLED STABILIZER FOR SURGICAL PROCEDURES 审中-公开
标题翻译：冷冻稳定器用于外科手术
公开(公告)号：WO2003084408A1
公开(公告)日：2003-10-16
申请号：PCT/US2003/006705
申请日：2003-03-05
申请人： GENZYME CORPORATION
发明人： MARTIN, Thomas, E. , VALERIO, Michael, A.
IPC分类号： A61B17/02
CPC分类号： A61B17/02 , A61B2017/0243 , A61F2007/101
摘要： A cooled stabilizer is provided for use in coronary bypass grafting surgical procedures. The cooled stabilizer can be attached to a surgical retractor for providing localized traction, stabilization and/or hemostasis to a predetermined area of body tissue. The stabilizer includes cooling channels and/or pads forming a continuous bottom surface for providing a chilled surface to contact body tissue. In one example, the cooled stabilizer can be shaped as a horseshoe with chilled surfaces over horseshoe sections and optionally over a heel.
摘要翻译：提供冷却的稳定器用于冠状动脉旁路移植手术。冷却的稳定器可以附接到手术牵开器，用于提供局部牵引，稳定和/或止血到身体组织的预定区域。稳定器包括形成连续底表面的冷却通道和/或垫，用于提供冷却表面以接触身体组织。在一个示例中，冷却的稳定器可以形成为具有马蹄形部分上的冷却表面并且任选地在鞋跟上的马蹄形。

10. 发明申请

WO1996030111A1 PORTABLE DEVICE FOR PRESERVING ORGANS BY STATIC STORAGE OR PERFUSION 审中-公开
标题翻译：通过静态储存或灌注保存器官的便携式设备
公开(公告)号：WO1996030111A1
公开(公告)日：1996-10-03
申请号：PCT/US1996004235
申请日：1996-03-27
申请人： ORGAN, INC. , LIFE RESUSCITATION TECHNOLOGIES, INC.
发明人： ORGAN, INC. , LIFE RESUSCITATION TECHNOLOGIES, INC. , FAHY, Gregory, M.
IPC分类号： B01F03/04
CPC分类号： A01N1/02 , A01N1/0247 , A01N1/0273 , A61B2017/00969 , A61F2007/101 , F25B9/004 , F25D16/00
摘要： An organ storage device permits both static storage and perfusion of an organ (223) without removing the organ from an organ container (11). The organ storage device includes a contoured organ container (11). The organ container (11) is stored and transported in an insulated temperature controlled static storage module (200). The storage module (200) is equipped with monitoring devices for monitoring the organ (223) during storage and transportation. The storage module (200) is also equipped with an assembly (122) for connecting the organ container to a perfusion module.
摘要翻译：器官储存装置允许器官（223）的静态储存和灌注，而不从器官容器（11）移除器官。所述器官储存装置包括形状良好的器官容器（11）。器官容器（11）在绝热温度控制的静电储存模块（200）中储存和运输。存储模块（200）配备有用于在储存和运输期间监测器官（223）的监测装置。存储模块（200）还配备有用于将器官容器连接到灌注模块的组件（122）。

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