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1. 发明申请

WO2021096926A1 CONTRACEPTIVE MEDICAL DEVICES 审中-公开
公开(公告)号：WO2021096926A1
公开(公告)日：2021-05-20
申请号：PCT/US2020/059968
申请日：2020-11-11
申请人： POLY-MED, INC.
发明人： TAYLOR, Michael, Scott , GAERKE, Brian , GRAVETT, David , SOLIANI, Anna, Paola , GARCIA, Kyle
IPC分类号： A61K9/02 , A61K31/18 , A61M31/00
摘要： Disclosed herein are contraceptive medical devices that include at least a polymeric ring, a porous barrier material and an injection molding guide, where the guide may be symmetrical and/or have one or a plurality of planar surfaces, where the device may optionally administer at least one active agent.

2. 发明申请

WO2019126794A1 TUBULAR IMPLANTS WITH CONTROLLED BIODEGRADATION 审中-公开
公开(公告)号：WO2019126794A1
公开(公告)日：2019-06-27
申请号：PCT/US2018/067372
申请日：2018-12-21
申请人： POLY-MED, INC.
发明人： CARTLEDGE, Jennifer , CLINKSCALES, Kenneth, W. , ELVINGTON, Elizabeth , HYDE, James , JOHNS, Brad , TAYLOR, Michael, Scott
IPC分类号： A61F2/04
摘要： Implantable medical devices have zones of high in vivo stability that are adjacent to zones of relatively low in vivo stability, so that when these medical devices are implanted into a host, the zones of low in vivo stability degrade first and allow the formation of independent segments of relatively intact high in vivo stability bands that are sufficiently small that they may pass from the host in a non-harmful manner.

3. 发明申请

WO2017223526A1 MEDICAL IMPLANTS HAVING MANAGED BIODEGRADATION 审中-公开
标题翻译：具有管理生物降解的医疗植物
公开(公告)号：WO2017223526A1
公开(公告)日：2017-12-28
申请号：PCT/US2017/039130
申请日：2017-06-23
申请人： POLY-MED, INC.
发明人： TAYLOR, Michael, Scott , CARTLEDGE, Jennifer , GRAY, Kenneth, David, Jr.
IPC分类号： A61F2/88 , A61F2/90 , A61F2/07 , A61L31/08 , A61L31/14
摘要： Medical implants that include a containment layer surrounding, or surrounded by, a biodegradable medical device provide the benefit that pieces formed during degradation of the medical device are held within a constrained place and thus do not causes injury to a hosts.
摘要翻译：包括围绕生物可降解医疗装置或被生物可降解医疗装置包围的容纳层的医疗植入物提供了这样的益处，即在医疗装置的降解期间形成的碎片被保持在受限位置内，并且因此不会导致对一个主机。

4. 发明申请

WO2017099820A3 SYNTHETIC IMPLANT DEVICE REPLICATING NATURAL TISSUE STRUCTURE AND METHODS OF MAKING SAME 审中-公开
标题翻译：复制天然组织结构的合成植入装置及其制造方法
公开(公告)号：WO2017099820A3
公开(公告)日：2017-08-10
申请号：PCT/US2016000125
申请日：2016-12-10
申请人： POLY-MED INC
发明人： MCCULLEN SETH DYLAN , CULBREATH CLAYTON JOSEPH , VAUGHN MICHAEL AARON , TAYLOR MICHAEL SCOTT
IPC分类号： A61F5/01 , A61K9/70
CPC分类号： A61L27/00 , A61F2/0063 , A61F2210/0004 , A61F2240/001 , A61F2250/003 , A61F2250/0039
摘要： A composite implant device for use in a medical application, comprising a synthetically-derived mesh that mimics particular critical aspects of a biologically-derived mesh. The composite implant device can be used for the reinforcement and reconstruction of tissues within the body and can be comprised of a majority of synthetic components and minority of naturally-derived components which mimic the structure and function of a naturally-derived mesh.
摘要翻译：一种用于医疗应用的复合植入装置，包括模拟生物衍生网格的特定关键方面的合成衍生网格。该复合植入装置可用于体内组织的增强和重建，并且可由大部分合成组分和少数天然衍生组分组成，这些组分模仿天然衍生的网状物的结构和功能。

5. 发明申请

WO2017099820A2 SYNTHETIC IMPLANT DEVICE REPLICATING NATURAL TISSUE STRUCTURE AND METHODS OF MAKING SAME 审中-公开
标题翻译：复制天然组织结构的合成植入装置及其制造方法
公开(公告)号：WO2017099820A2
公开(公告)日：2017-06-15
申请号：PCT/US2016/000125
申请日：2016-12-10
申请人： POLY-MED, INC.
发明人： MCCULLEN, Seth, Dylan , CULBREATH, Clayton, Joseph , VAUGHN, Michael, Aaron , TAYLOR, Michael, Scott
IPC分类号： A61F5/01 , A61K9/70
CPC分类号： A61L27/00 , A61F2/0063 , A61F2210/0004 , A61F2240/001 , A61F2250/003 , A61F2250/0039
摘要： A composite implant device for use in a medical application, comprising a synthetically-derived mesh that mimics particular critical aspects of a biologically-derived mesh. The composite implant device can be used for the reinforcement and reconstruction of tissues within the body and can be comprised of a majority of synthetic components and minority of naturally-derived components which mimic the structure and function of a naturally-derived mesh.
摘要翻译：一种用于医疗应用的复合植入装置，包括模拟生物衍生网格的特定关键方面的合成衍生网格。该复合植入装置可用于体内组织的增强和重建，并且可以由大多数合成组分和少数自然衍生组分组成，这些组分模仿天然衍生的网状物的结构和功能。

6. 发明申请

WO2017096203A1 DOUBLE NETWORK HYDROGEL WITH ANIONIC POLYMER AND USES THEREOF 审中-公开
标题翻译：具有阴离子聚合物的双网络水凝胶及其应用
公开(公告)号：WO2017096203A1
公开(公告)日：2017-06-08
申请号：PCT/US2016/064682
申请日：2016-12-02
申请人： POLY-MED, INC.
发明人： VAUGHN, Michael, Aaron
IPC分类号： A61F2/30 , A61L27/52 , C08F261/04 , C08F283/00 , C08J3/075
CPC分类号： C08J3/075 , A61L27/16 , A61L27/26 , A61L27/52 , A61L2430/06 , C08F220/06 , C08F222/385 , C08F2220/585 , C08J3/246 , C08J2329/04 , C08J2433/02 , C08L29/04
摘要： A double network hydrogel consists of a first network and a second network, where the first network is, or includes, a first polymer that is formed, at least in part, of -CH 2 -CH(OH)- units, and the second network is, or includes, a second polymer that is formed, at least in part, of carboxyl (COOH)-containing units or salts thereof, sulfonyl (SO 3 H)-containing units or salts thereof, and at least one of hydroxyl (OH)-containing units or amino (NH 2 )-containing units, where the hydrogel may be used as a cartilage replacement.
摘要翻译：双网络水凝胶由第一网络和第二网络组成，其中第一网络是或包括第一聚合物，所述第一聚合物至少部分地由-CH 2 -CH（OH） - 单元，并且第二网络是或包括第二聚合物，所述第二聚合物至少部分地由含有羧基（COOH）的单元或其盐，磺酰基（SO _{含有羟基（OH）的单元或含氨基（NH 2）的单元中的至少一种，其中可使用水凝胶作为软骨替代品。}

7. 发明申请

WO2016100915A2 ABSORBABLE COPOLYMERS WITH IMPROVED THERMAL STABILITY 审中-公开
标题翻译：具有改进的热稳定性的可吸收共聚物
公开(公告)号：WO2016100915A2
公开(公告)日：2016-06-23
申请号：PCT/US2015/066869
申请日：2015-12-18
申请人： POLY-MED, INC.
发明人： GRAY, Kenneth, David , VAUGHN, Michael, Aaron
IPC分类号： C08G63/64 , A61L15/64
CPC分类号： C08G63/64 , A61L15/26 , A61L15/64 , A61L27/34 , A61L27/54 , A61L27/58 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/604 , A61L2300/606 , C08G63/85 , C08G63/91 , C08L67/04
摘要： The present invention relates to absorbable block copolymers with improved characteristics including thermal stability, molecular weight consistency, inherent viscosity retention following melt extrusion, and fibers made from the polymers exhibit increased strength.
摘要翻译：本发明涉及具有改进特性的可吸收嵌段共聚物，包括热稳定性，分子量一致性，熔融挤出后的固有粘度保留性，以及由聚合物制成的纤维表现出增强的强度。

8. 发明申请

WO2013151563A3 POLYMERIC MESH PRODUCTS, METHOD OF MAKING AND USE THEREOF 审中-公开
标题翻译：聚合物制品，其制备方法和用途
公开(公告)号：WO2013151563A3
公开(公告)日：2014-02-13
申请号：PCT/US2012033336
申请日：2012-04-12
申请人： POLY MED INC , PENISTON SHAWN J , HILAS GEORGIOS T
发明人： PENISTON SHAWN J , HILAS GEORGIOS T
IPC分类号： D04B21/12 , A61F2/00 , A61F13/00
CPC分类号： D04B21/12 , A61F2/0063 , A61F2002/0068 , A61F2210/0004 , A61F2250/0031 , D10B2509/08 , Y10T442/184
摘要： A polymeric mesh is disclosed. The polymeric mesh comprises an absorbable polymeric fiber and a non-absorbable polymeric fiber knitted together to form an interdependent, co-knit mesh structure. Also disclosed are methods for making the polymeric mesh and methods for using the polymeric mesh.
摘要翻译：公开了聚合物网。聚合物网包括可吸收的聚合物纤维和不可吸收的聚合物纤维，其编织在一起以形成相互依赖的共同编织网状结构。还公开了制备聚合物网的方法和使用聚合物网的方法。

9. 发明申请

WO2005074415A3 ANTIMICROBIAL, SYNTHETIC, FIBROUS, AND TUBULAR MEDICAL DEVICES 审中-公开
标题翻译：抗生素，合成，纤维和管状医疗器械
公开(公告)号：WO2005074415A3
公开(公告)日：2009-04-09
申请号：PCT/US2004028421
申请日：2004-09-01
申请人： POLY MED INC , SHALABY SHALABY W
发明人： SHALABY SHALABY W
IPC分类号： A61F13/00 , A01N25/34 , A01N31/16 , A01N47/30 , A01N59/12 , A61F15/00 , A61F17/00 , A61K9/00 , A61K31/00 , A61K35/00 , A61K36/00 , A61K38/00
CPC分类号： A61L29/16 , A01N25/10 , A01N25/34 , A61L17/005 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/602 , Y10T442/2525 , Y10T442/30 , Y10T442/3707 , Y10T442/40 , Y10T442/494 , A01N31/16 , A01N33/12 , A01N43/60 , A01N47/30 , A01N47/44
摘要： The present invention is directed toward antimicrobial absorbable and non-absorbable fibrous and tubular medical devices comprising synthetic polymers and one or more antimicrobial agent molecularly dispersed within the surface to allow the continuous release of said agent or agents under simulated physiologic conditions for at least one week.
摘要翻译：本发明涉及抗微生物可吸收和不可吸收的纤维和管状医疗装置，其包括合成聚合物和一种或多种分子分散在表面内的抗微生物剂，以允许所述试剂或试剂在模拟生理条件下连续释放至少一周。

10. 发明申请

WO2008069915A2 SELECTIVELY ABSORBABLE/BIODEGRADABLE, FIBROUS COMPOSITE CONSTRUCTS AND APPLICATIONS THEREOF 审中-公开
标题翻译：选择性可吸收/可生物降解，复合材料的复合结构及其应用
公开(公告)号：WO2008069915A2
公开(公告)日：2008-06-12
申请号：PCT/US2007024124
申请日：2007-11-19
申请人： POLY MED INC , SHALABY SHALABY W , PENISTON SHAWN J , CARPENTER KIMBERLY A
发明人： SHALABY SHALABY W , PENISTON SHAWN J , CARPENTER KIMBERLY A
IPC分类号： A61B17/04 , A61B17/56
CPC分类号： A61L27/48 , A61L27/54 , A61L27/58 , C08L23/06 , C08L2203/12 , C08L67/04
摘要： A family of selectively absorbable/biodegradable, fibrous composite constructs includes different combinations of biostable and absorbable/biodegradable yarns assembled as initially interdependent, load-bearing components, transitioning to exhibit independent functional properties during in vivo end-use. The family of constructs consists of two groups, one group is made of fiber-reinforced composites of high compliance, absorbable matrices of segmented polyaxial copolyesters reinforced with multifilament yarn constructs, which are combinations of ultrahigh molecular weight polyethylene fibers and at least one absorbable/ biodegradable fiber selected from silk fibers and multifilament yarns made from linear segmented, l-lactide copolyesters and poly (3-hydroxyalkanoates) are useful in orthopedic, maxillofacial, urological, vascular, hernial repair and tissue engineering applications. The second group is made of coated and uncoated, warp-knitted mesh constructs for use in hernial, vascular, and urological tissue repair and tissue engineering.
摘要翻译：一系列可选择性吸收/可生物降解的纤维复合材料构造包括生物稳定和可吸收/可生物降解的纱线的不同组合，其组装为最初相互依赖的承载组分，在体内最终用途中转变为显示独立的功能特性。构建体组由两组组成，一组由高柔顺性的纤维增强复合材料制成，由多丝纱构造物增强的分段多轴共聚酯的可吸收基质，其是超高分子量聚乙烯纤维和至少一种可吸收/可生物降解的组合选自丝线纤维和由线性分段的丙交酯共聚酯和聚（3-羟基链烷酸酯）制成的复丝纱线的纤维可用于矫形，颌面，泌尿，血管，疝修补和组织工程应用。第二组由用于疝，血管和泌尿组织修复和组织工程的涂层和未涂层的经编网状构造物制成。

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