专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO1997047390A1 ABSORPTION-ENHANCED DIFFERENTIAL EXTRACTION DEVICE 审中-公开
标题翻译：吸收增强的差异提取装置
公开(公告)号：WO1997047390A1
公开(公告)日：1997-12-18
申请号：PCT/US1997010307
申请日：1997-06-13
申请人： UNIVERSITY OF WASHINGTON
发明人： UNIVERSITY OF WASHINGTON , YAGER, Paul , BRODY, James, P.
IPC分类号： B03B05/28
CPC分类号： G01N30/0005 , A61M1/3679 , B01J19/0093 , B01J2219/00828 , B01J2219/00952 , B01J2219/00995 , B03B5/00 , G01N30/02 , G01N30/6095 , G01N2030/582 , Y10S366/01 , B01D15/3804
摘要： This invention provides an extraction device and method for extracting desired particles from a sample stream (2) containing the desired particles. The device comprises a sample stream inlet (1); an extraction stream inlet (5); an extraction channel (7) in fluid communication with the sample stream inlet (1) and the extraction stream inlet (5) for receiving a sample stream (2) from the sample stream inlet (1) in adjacent laminar flow with an extraction stream (4) from the extraction stream inlet (5); a sequestering material within the extraction channel (7) for capturing desired particles (18) in the extraction stream (9); a by-product stream outlet (15) in fluid communication with the extraction channel (7) for receiving a by-product stream (12) comprising at least a portion of the sample stream (2) from which desired particles (18) have been extracted; and a product outlet (14) in fluid communication with the extraction channel (7) for receiving a product comprising the sequestering material and at least a portion of the desired particles (18).
摘要翻译：本发明提供了一种从含有所需颗粒的样品流（2）中提取所需颗粒的提取装置和方法。该装置包括样品流入口（1）; 提取流入口（5）; 与样品流入口（1）和提取流入口（5）流体连通的提取通道（7），用于从相邻层流中的样品流入口（1）接收样品流（2），其中提取流入口 4）从提取流入口（5）中取出; 提取通道（7）内的螯合材料，用于捕获提取流（9）中的所需颗粒（18）; 与所述提取通道（7）流体连通的副产物流出口（15），用于接收副产物流（12），所述副产物流包含至少一部分样品流（2），所述样品流从所述至少一部分从所述样品流提取; 以及与所述提取通道（7）流体连通的产品出口（14），用于接收包含隔离材料和至少一部分所需颗粒（18）的产品。

2. 发明申请

WO1997000442A1 MICROFABRICATED DIFFERENTIAL EXTRACTION DEVICE AND METHOD 审中-公开
标题翻译：微量差异提取装置及方法
公开(公告)号：WO1997000442A1
公开(公告)日：1997-01-03
申请号：PCT/US1996010308
申请日：1996-06-14
申请人： THE UNIVERSITY OF WASHINGTON
发明人： THE UNIVERSITY OF WASHINGTON , YAGER, Paul , BRODY, James, P. , HOLL, Mark, R. , FORSTER, Fred, K. , GALAMBOS, Paul, C.
IPC分类号： G01N30/00
CPC分类号： B01D11/0492 , B01D11/0496 , B01F13/0059 , B01F13/0093 , B01F2005/0031 , B01J19/0093 , B01J2219/00783 , B01J2219/00828 , B01J2219/00889 , B01J2219/00905 , B01J2219/00952 , B01J2219/0097 , B01J2219/00995 , G01N15/06 , G01N30/0005 , G01N2001/4072 , G01N2035/00237 , Y10S366/01 , Y10T436/255
摘要： This invention provides a microfabricated extraction system and methods for extracting desired particles from a sample stream containing desired and undesired particles. The sample stream is placed in laminar flow contact with an extraction stream under conditions in which inertial effects are negligible. The contact between the two streams is maintained for a sufficient period of time to allow differential transport of the desired particles from the sample stream into the extraction stream. In a preferred embodiment the differential transport mechanism is diffusion. The extraction system of this invention coupled to a microfabricated diffusion-based mixing device and/or sensing means allows picoliter quantities of fluid to be processed or analyzed on devices no larger than silicon wafers.
摘要翻译：本发明提供了一种微加工提取系统和从含有所需和不需要的颗粒的样品流中提取所需颗粒的方法。在惯性效应可忽略的条件下，将样品流与提取流层流接触。保持两个物流之间的接触足够的时间，以便将期望的颗粒从样品流中差分输送到萃取物流中。在优选实施例中，差分传送机构是扩散。本发明的提取系统耦合到基于微制造的基于扩散的混合装置和/或感测装置允许在不大于硅晶片的装置上处理或分析皮升数量的流体。

3. 发明申请

WO1997045644A1 VALVELESS LIQUID MICROSWITCH 审中-公开
标题翻译：气动液晶显示器
公开(公告)号：WO1997045644A1
公开(公告)日：1997-12-04
申请号：PCT/US1997007732
申请日：1997-05-06
申请人： THE UNIVERSITY OF WASHINGTON
发明人： THE UNIVERSITY OF WASHINGTON , BRODY, James, P.
IPC分类号： F15C01/00
CPC分类号： B01L3/502738 , B01L2200/146 , B01L2300/0816 , B01L2300/0864 , B01L2300/14 , B01L2400/0487 , B01L2400/0622 , F15C1/00 , G01N2015/149 , Y10T137/4774 , Y10T137/479 , Y10T137/7303
摘要： This invention provides a valveless method and apparatus for high speed switching of liquid flow between intersecting michrochannels. Liquid flow is controlled by manipulating external driving pressures. The switch comprises threee intersecting microchannels, each having a liquid reservoir at its nonintersecting end for liquid inlet and outlet. It further includes a means for applying a driving pressure to each reservoir and a means for switching the driving pressures. The microswitch of this invention operates to establish a liquid flow from a first channel to a second channel by applying a pressure differential between the first and second reservoirs, while simultaneously preventing flow into the third channel by applying a pressure to the third reservoir which equals the pressure at the junction of the three channels. By switching one or more driving pressures, the flow to the second channel can be stopped and the liquid flow redirected to the third channel. This invention further includes switches wherein more than three channels are included in the flow network, either intersecting in a single junction or in multiple junctions.
摘要翻译：本发明提供了一种用于在相交的分子混合物之间高速切换液体流的无阀方法和装置。通过操纵外部驱动压力来控制液体流量。开关包括三相交的微通道，每个微通道在其不间断端具有用于液体入口和出口的液体储存器。它还包括用于向每个储存器施加驱动压力的装置和用于切换驱动压力的装置。本发明的微动开关通过在第一和第二储存器之间施加压差来建立从第一通道到第二通道的液体流动，同时通过向第三储存器施加压力来同时防止流入第三通道，该压力等于压力在三通道的交界处。通过切换一个或多个驱动压力，可以停止到第二通道的流动，并且液流重新定向到第三通道。本发明还包括开关，其中多于三个通道包括在流动网络中，或者在单个结或多个连接处相交。

4. 发明申请

WO1997000121A1 TANGENTIAL FLOW PLANAR MICROFABRICATED FLUID FILTER 审中-公开
标题翻译： TANGENTIAL流量平面微流化过滤器
公开(公告)号：WO1997000121A1
公开(公告)日：1997-01-03
申请号：PCT/US1996009946
申请日：1996-06-14
申请人： THE UNIVERSITY OF WASHINGTON
发明人： THE UNIVERSITY OF WASHINGTON , BRODY, James, P. , OSBORN, Thor, D.
IPC分类号： B01D69/02
CPC分类号： G01N33/491 , B01D39/1692 , B01D61/18 , B01D67/0058 , B01D67/0062 , B01D71/02 , B01D2323/00 , B01D2323/08 , B01D2323/12 , B01L3/502753 , B01L2200/12 , B01L2300/0681 , B01L2300/0816 , B01L2300/0864 , B01L2400/0406 , B01L2400/0487 , Y10S977/904 , Y10T436/25375
摘要： A microfilter utilizing the principles of tangential flow to prevent clogging, and slopped channel sides to overcome surface tension effects is provided which has feed inlet and exit connected by a feed flow channel; a barrier channel parallel to the feed flow channel, and a filtrate collection channel parallel to the barrier channel so that liquid can flow from the feed flow channel through the barrier channel which is too small to accommodate the particles, into the filtrate collection channel, and from then through a filtrate flow channel to a filtrate exit. Several picoliters of cell-free plasma are recovered from one drop of blood for analysis.
摘要翻译：提供利用切向流动原理以防止堵塞的微过滤器，以及斜坡通道侧以克服表面张力效应，其具有通过进料流动通道连接的进料入口和出口; 平行于进料流通道的阻挡通道和平行于阻挡通道的滤液收集通道，使得液体可以从进料流动通道通过阻挡通道，其过小而不能容纳颗粒进入滤液收集通道，以及从此通过滤液流通道到滤液出口。从一滴血液中回收几个无细胞血浆的皮升卵，用于分析。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式