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    • 1. 发明申请
    • PISCIRICKETTSIA SALMONIS ANTIGENS AND USE THEREOF
    • PISCIRICKETTSIA SALMONIS抗体及其用途
    • WO2005035558A3
    • 2005-10-13
    • PCT/IB2004003339
    • 2004-10-01
    • THIRY MICHELDHEUR INGRID
    • THIRY MICHELDHEUR INGRID
    • A61K39/00A61K39/02A61K39/295C07K14/195C07K14/29C07K16/12C12N15/31
    • C07K14/195A61K39/00
    • The present invention discloses novel proteins, e.g., antigens, from Piscirickettsia salmonis. The present invention further discloses nucleic acids that encode these proteins. The present invention also discloses the use of the proteins, e.g., antigens, and nucleic acids to prepare vaccines against salmonid rickettsial septicemia (SRS). The present invention further provides recombinant Yersinia ruckeri cells to be used to construct vaccines against SRS. The present invention also discloses vaccines that can be used to protect fish from Piscirickettsia salmonis, as well as other pathogens. In addition, the present invention discloses methods of using the vaccines of the present invention to protect fish from SRS as well as from other pathogenic diseases.
    • 本发明公开了来自沙门氏菌的新型蛋白质,例如抗原。 本发明还公开了编码这些蛋白质的核酸。 本发明还公开了蛋白质例如抗原和核酸用于制备针对鲑鱼立克次体败血症(SRS)的疫苗的用途。 本发明还提供了用于构建针对SRS的疫苗的重组Yersinia ruckeri细胞。 本发明还公开了可用于保护鱼类从沙门氏菌和其他病原体中获得的疫苗。 此外,本发明公开了使用本发明的疫苗来保护鱼类免受SRS以及其它病原性疾病的方法。