专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2014083109A3 PROCESS FOR THE REMOVAL AND RETURN OF A CATALYST TO A LIQUID PHASE MEDIUM AND ITS USE IN CROSS-COUPLING REACTIONS 审中-公开
公开(公告)号：WO2014083109A3
公开(公告)日：2014-06-05
申请号：PCT/EP2013/074974
申请日：2013-11-28
申请人： PHOSPHONICS LTD , MURRAY, Paul
发明人： MURRAY, Paul , WILKES, Robin , NORTH, Christopher
IPC分类号： B01J31/06 , B01J31/16 , B01J31/24 , C08G77/385 , C08G77/388 , C08G77/392 , C08G77/395 , C07B37/04 , C07B43/00
摘要： A process for the selective removal of a component from a liquid phase and subsequently returning the component to a liquid phase is disclosed. A novel compound of formula (I) [SUP]-[[L]-[G]]a (I) in which L is a linking group, G is an aryl group having a leaving group LG selected from Cl, Br, I, sulfonate such as triflate, a diazo group, a nitrile, an ester and an alkoxy group and substituent Q is selected from H, NR2, OR, C02R, F, Cl, N02 CN and SUP is a support having a plurality of groups -[L]-[G] bound to the support is contacted with the liquid phase to bind the component to the compound I thereby forming a captured component which is separated from and may be returned to the liquid phase. The compound I is especially useful in binding homogeneous catalysts to remove it from a reaction medium and selectively returning the catalyst to the reaction medium at a later stage. The compound is particularly useful for cross-coupling reactions, for example in Suzuki reactions.

2. 发明申请

WO2009049911A1 FUNCTIONALISED MATERIALS AND USES THEREOF 审中-公开
标题翻译：功能材料及其用途
公开(公告)号：WO2009049911A1
公开(公告)日：2009-04-23
申请号：PCT/EP2008/008867
申请日：2008-10-20
申请人： PHOSPHONICS LTD , WILSON, John, Robert, Howe , GALAFFU, Nico , MAN, Siud, Pui , WILKES, Robin
发明人： WILSON, John, Robert, Howe , GALAFFU, Nico , MAN, Siud, Pui , WILKES, Robin
IPC分类号： C07F7/21 , C08G77/28 , C08G77/50 , A61K9/14 , C01B33/14
CPC分类号： C07F7/21 , A61K47/24 , A61K47/34
摘要： [(O 3/2 )Si CH 2 CH 2 SX] a [Si (O 4/2 )] b [WSi (O 3/2 )] c [VSi (O 3/2 )] d wherein X is selected from (CR 1 R 2 ) e NR 5 CO NHR, (CR 1 R 2 ) e NR 5 CS NHR, W when present is selected from (CR 6 R 7 ) e ZR, (CH 2 ) 3 SR1 (CH 2 ) 3 NRR 1 , (CH 2 ) e SR 8 , CH 2 CH 2 S (CR 1 R 2 ) f NR 5 CO NHR, CH 2 CH 2 S (CR 1 R 2 ),NR 5 CS NHR, CH 2 CH 2 S (CH 2 ) f OR; Z is O or S, R, R 1-7 are independently selected from hydrogen, alkyl group, aryl group or alkylaryl group, R 8 is selected from [CH 2 CH 2 NR 1 ] P R 2 and (CR 1 R 2 ) m SR 9 where R 9 is hydrogen, C 1-22 -alkyl group, and V is a group which is optionally substituted and selected from a C 1-22 -alkyl group, C 2-22 -alkenyl group, a C 2-22 -alkynyl group or an aryl group. The compounds are useful as immobilisation materials for bio-molecules including enzymes, cation and anion exchangers, organic and inorganic compound scavengers, solid phase purification or extraction materials, removal and purification of biological compounds including endotoxins, anti-microbial agents, hydrophilicity modifiers, flame proofing agents, antistatic agents, coatings for biomedical devices, water repellent films and coatings, solid phase synthesis materials and chromatography materials.
摘要翻译： [（O3 / 2）Si CH2CH2SX] a [Si（O4 / 2）] b [WSi（O3 / 2）] c [VSi（O3 / 2）] d其中X选自（CR1R2）eNR5 CO NHR，（ CR1R2）eNR5 CS NHR，当存在时，W选自（CR 6 R 7）e ZR，（CH 2）3 SR 1（CH 2）3 NRR1，（CH 2）e SR 8，CH 2 CH 2 S（CR 1 R 2）f NR 5 CO NHR，CH 2 CH 2 S（CR 1 R 2） NHR，CH 2 CH 2 S（CH 2）f OR; Z是O或S，R，R 1-7独立地选自氢，烷基，芳基或烷芳基，R8选自[CH2CH2NR1] PR2和（CR1R2）m SR9，其中R9是氢，C1-22- 烷基，V是任选被取代并选自C 1-22烷基，C 2--22链烯基，C 2--22炔基或芳基的基团。该化合物可用作包括酶，阳离子和阴离子交换剂，有机和无机化合物清除剂，固相纯化或提取物质在内的生物分子的固定物质，除去和纯化包括内毒素，抗微生物剂，亲水性改性剂，火焰防静电剂，生物医学装置用涂料，防水膜和涂料，固相合成材料和色谱材料。

3. 发明申请

WO2014083112A1 SUPPORTED COMPOUND COMPRISING LINKER AND LEAVING GROUP 审中-公开
标题翻译：包含连接器和开放组的支持化合物
公开(公告)号：WO2014083112A1
公开(公告)日：2014-06-05
申请号：PCT/EP2013/074984
申请日：2013-11-28
申请人： PHOSPHONICS LTD
发明人： WILKES, Robin , NORTH, Christopher
IPC分类号： C08G77/385 , C08G77/388 , C08G77/392 , C08G77/395 , B01J20/32
CPC分类号： C07F7/10 , B01J31/069 , B01J31/1633 , B01J31/1658 , B01J31/2409 , B01J2231/321 , B01J2231/42 , B01J2231/4211 , B01J2531/0205 , B01J2531/16 , B01J2531/80 , B01J2531/824 , B01J2531/842 , B01J2531/847 , C07F7/0834 , C07F17/02 , C08G77/385 , C08G77/388 , C08G77/392 , C08G77/395 , Y02P20/588
摘要： A novel compound of formula (I) [SUP]-[[L]-[G]] a (I) in which L is a linking group, G is an aryl group having a leaving group LG selected from Cl, Br, I, sulfonate such as triflate, a diazo group, a nitrile, an ester and an alkoxy group and substituent Q is selected from H, NR 2 , OR, CO 2 R, F, CI, NO 2 CN and SUP is a support having a plurality of groups -[L]-[G] bound to the support is contacted with the liquid phase to bind a component to the compound I thereby recovering the component from the liquid phase.
摘要翻译：其中L是连接基团的式（I）[SUP] - [[L] - [G]] a（I）的新化合物，G是具有选自Cl，Br，I 磺酸酯如三氟甲磺酸酯，重氮基，腈，酯和烷氧基，取代基Q选自H，NR2，OR，CO2R，F，C1，NO2CN和SUP是具有多个基团的支持物 - 与载体接触的[L] - [G]与液相接触以将组分与化合物I结合，从而从液相中回收组分。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式