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1. 发明申请

WO2003101277A3 NONINVASIVE DETECTION OF A PHYSIOLOGIC PARAMETER WITHIN A BODY TISSUE OF A PATIENT 审中-公开
公开(公告)号：WO2003101277A3
公开(公告)日：2003-12-11
申请号：PCT/US2003/016033
申请日：2003-05-20
申请人： OPTICAL SENSORS INCORPORATED
发明人： ANDERSON, Edward, J. , REYNOLDS, Brandon, W. , WINGER, Kent, R. , KIMBALL, Victor, E.
IPC分类号： A61B5/02
摘要： A device for contacting a surface of a tissue within a patient's body to determine a physiological parameter of the patient. The device typically comprises a sensor (30) responsive to the physiological parameter and a probe (10) housing the sensor. The probe is constructed to allow the sensor to be secured at a sensing area (18) adjacent to a surface of a patient's tissue, without need for an adhesive and without disturbing the blood flow within the measurement region of the tissue. The device may also include a means (16) for reducing interference in the sensing area. Preferably, the device further comprises an indicating means (40) operably connected to the sensor for indicating an analyte quantity and/or concentration associated with the physiologic parameter. The invention also provides a method for determining a physiologic parameter of a patient.

2. 发明申请

WO2007030379A2 SYSTEM FOR AUTOMATED MEASUREMENT OF SKIN PERFUSION PRESSURE 审中-公开
标题翻译：自动测量皮肤刺激压力的系统
公开(公告)号：WO2007030379A2
公开(公告)日：2007-03-15
申请号：PCT/US2006/034116
申请日：2006-08-30
申请人： OPTICAL SENSORS INCORPORATED , BARTNIK, Daniel, J. , REYNOLDS, Brandon, W. , PIERSKALLA, Irvin, T.
发明人： BARTNIK, Daniel, J. , REYNOLDS, Brandon, W. , PIERSKALLA, Irvin, T.
IPC分类号： A61B5/02
CPC分类号： A61B5/0261 , A61B5/14552 , A61B5/6833 , A61B5/6842 , A61B5/6843 , A61B5/7207
摘要： An automatic skin perfusion measuring system including instrumentation that automatically analyzes perfusion measurements to identify motion artifact and SPP values and a sensor placement device is provided. The instrumentation is configured to ignore motion artifact. Perfusion measurements are designated as SPP values if various criteria are met. SPP value criteria pertain to factors including cuff pressure, perfusion, perfusion change percentages relative to previous and subsequent perfusion measurements, and whether perfusion measurements are increasing or decreasing relative to previous and subsequent perfusion measurements. The sensor placement device assures reliable data is produced when multiple measurements are desired.
摘要翻译：一种自动皮肤灌注测量系统，包括自动分析灌注测量以识别运动伪影和SPP值的仪器以及传感器放置装置。仪器被配置为忽略运动伪影。如果满足各种标准，灌注测量被指定为SPP值。 SPP值标准涉及包括袖带压力，灌注，相对于先前和随后灌注测量的灌注变化百分比以及灌注测量是否相对于先前和之后的灌注测量值增加或减少的因素。传感器放置装置确保在需要多次测量时产生可靠数据。

3. 发明申请

WO2008031030A2 IMPROVED IMPEDANCE CARDIOGRAPHY SYSTEM AND METHOD 审中-公开
标题翻译：改进的阻抗记录系统和方法
公开(公告)号：WO2008031030A2
公开(公告)日：2008-03-13
申请号：PCT/US2007/077882
申请日：2007-09-07
申请人： OPTICAL SENSORS INCORPORATED , BARTNIK, Daniel, J. , REYNOLDS, Brandon, W.
发明人： BARTNIK, Daniel, J. , REYNOLDS, Brandon, W.
IPC分类号： A61B5/0452
CPC分类号： A61B5/0452
摘要： An improved method and system for measuring and reporting heart valve activity combines information obtained from independent signals with information obtained from ICG signals, such that signals derived from heart valve activity may be used as confirmation that the ICG system is accurately identifying heart valve activity. The method and system of the present invention also provide improved accuracy in reported values such as PEP, LVET, STR, SV, and CO. In addition, the method and system of the present invention provide improved accuracy of graphical representations of heart activity where the graphical representations include identifying heart valve activity.
摘要翻译：用于测量和报告心脏瓣膜活动的改进方法和系统将从独立信号获得的信息与从ICG信号获得的信息相结合，使得从心脏瓣膜活动得到的信号可以用作ICG系统准确地识别心脏瓣膜活动的确认。本发明的方法和系统还提供了诸如PEP，LVET，STR，SV和CO之类的报告值的改善的精度。此外，本发明的方法和系统提供了心脏活动的图形表示的改进的准确性，其中图形表示包括识别心脏瓣膜活动。

4. 发明申请

WO2004042870A2 CARTRIDGE FOR PACKAGING A SENSOR IN A FLUID CALIBRANT 审中-公开
标题翻译：用于在流体校准器中包装传感器的盒
公开(公告)号：WO2004042870A2
公开(公告)日：2004-05-21
申请号：PCT/US2003/015777
申请日：2003-05-20
申请人： OPTICAL SENSORS INCORPORATED
发明人： PIERSKALLA, Irvin, T. , WINGER, Kent, R. , REYNOLDS, Brandon, W. , KIMBALL, Victor, E.
IPC分类号： H01R
CPC分类号： B01L3/508 , B01L3/502 , B01L2200/148 , B01L2300/041 , Y10T436/10
摘要： The invention relates to a cartridge for packaging an analyte-containing fluid calibrant. The cartridge is formed from a container having an opening sealed by a sealing member. A septum divides the container into a calibrant compartment and an outer compartment. A probe is provided comprising an analyte-detecting portion and a connecting portion that allows for operative connection to a device for quantitating or determining the concentration of the analyte. The probe may extend sealingly through the septum such that the analyte-detecting portion is located in the calibrant compartment and the connecting portion is located in the outer compartment. The construction of the cartridge provides ease and reduces the likelihood of error in calibrating the probe. The inventionalso relates to a method of manufacturing the cartridge and a method for calibrating a device for analyte concentration determination and quantitation using the inventive cartridge.
摘要翻译：本发明涉及一种用于包装含分析物的流体校准剂的盒。盒由具有由密封构件密封的开口的容器形成。隔垫将容器分成一个校准室和一个外部隔室。提供了包含分析物检测部分和连接部分的探针，所述连接部分允许与用于定量或确定分析物浓度的装置有效连接。探针可以密封地延伸穿过隔膜，使得分析物检测部分位于校准体隔室中并且连接部分位于外部隔室中。墨盒的结构简化并减少了校准探头时出现错误的可能性。本发明还涉及制造所述盒的方法以及使用本发明的盒校准用于分析物浓度测定和定量的装置的方法。

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