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    • 2. 发明申请
    • PREPARING STERILE ARTICLES FROM POLYMERS CONTAINING A STABILISER BASED ON A POLY(OXYALKYLENE)
    • 基于聚合物(OXYALKYLENE)从含有稳定剂的聚合物制备无菌物品
    • WO0217972A3
    • 2002-09-06
    • PCT/GB0103889
    • 2001-08-30
    • OCCIDENTAL CHEM COSTEPHENS DINAH
    • WANG QINAGY SANDOR
    • A61L2/08C08F2/46C08J7/00C08K5/00C08L27/06C08L71/00C08K5/12
    • A61L2/081A61L2202/24C08K5/0008C08K5/12C08L27/06C08L71/02C08L2666/14C08L2666/22
    • A method of preparing a sterile article is disclosed. A polymer having a halogen-containing repeating unit is prepared that contains about 0.005 to about 65 phr of a stabiliser having the general formula TGOT', where each T is independently selected from R-, R-CO-, -P(R)2, -P(OR)2, Si(R)3, or -Si(OR)3, T' is T or A[GOT]n, each A is independently selected from LS-Sn(R)3-q(OLJ)q,(CH2)pS-Sn(R)3-q(S(CH2)p-J)q, LCO2Sn(R)3-q(OLCO-J)q, or LSn(Y)3-q(LJ)q when n is O, from CO, E, CO-E-CO, Si(R)2, Si(OR)2, (Si(R)2G)r, (CO-E-CO-G)r, (CO-G)r, or (E-G)r when n is 1, and from P, PO and trimellitate when n is 2, Y is -SLJ, -SLJ, -SLOR, -OLJ, -OLR, -S(CH2)p, each R is independently selected from R', aralkyl from C6 to C12, and aryl from C6 to C12, E is alkylene from C1 to C12, m is 1 to 20, n is 0 to 2, p is 0 to 10, q is 0 to 3 and r is 1 to 20. An article is made from the polymer and the article is sterilised with ionising radiation. Also disclosed are novel stabilisers for use in this method.
    • 公开了一种制备无菌制品的方法。 制备具有含卤素重复单元的聚合物,其含有约0.005至约65phr具有通式TGOT'的稳定剂,其中每个T独立地选自R-,R-CO-,-P(R)2 ,-P(OR)2,Si(R)3或-Si(OR)3,T'是T或A [GOT] n,每个A独立地选自LS-Sn(R)3-q )q,(CH 2)p -S-Sn(R)3-q(S(CH 2)pJ)q,LCO 2 Sn(R)3-q(OLCO-J)q或LSn(Y)3-q(LJ)q (CO),CO(CO)2,Si(OR)2,(Si(R)2G)r,(CO-E-CO-G) -G)r或(EG)r,当n为2时,P为PO和偏苯三酸,Y为-SLJ,-SLJ,-SLOR,-OLJ,-OLR,-S(CH2)p 每个R独立地选自R',C 6至C 12的芳烷基和C 6至C 12的芳基,E为C 1至C 12的亚烷基,m为1至20,n为0至2,p为0至10,q 为0〜3,r为1〜20。由聚合物制成制品,用电离辐射灭菌。 还公开了用于该方法的新型稳定剂。
    • 3. 发明申请
    • PREPARING STERILE ARTICLES FROM CERTAIN POLYMERS
    • 从某些聚合物制备不规则的文章
    • WO0217973A3
    • 2002-06-13
    • PCT/GB0103918
    • 2001-08-31
    • OCCIDENTAL CHEM COSTEPHENS DINAH
    • WANG QI
    • A61L2/08C08K5/04A61L2/00C08L27/06
    • A61L2/081A61L2202/24C08K5/04C08L27/06
    • A method of preparing a sterile article is disclosed. An article is prepared from a polymer into which is incorporated a stabilizer having the general formula: where each A is independently selected from E, OR, SR, and CO-R, and can join the aromatic ring to form an additional ring, E is R or R(OCH2R"CH)n, G is E, CO-R, -C(E)H-O-R, C(OE)(H)-O-R, -C(E)(R")R'"-OR, -C(E)(R")-R'"-CO-OR, C(OE)(R")-E'"-COOR, -C(OE)R'"-O-R, -C(OE)HR, or -C(OE)R2, J is A, each R is independently selected from H, R', R'"OR', R'"COOR', R'"C(OR")R", or R'"C(OR")R'"OR", each R' is independently selected from alkyl from C1 to C24, aryl from C6 to C24, alkaryl from C7 to C24, and aralkyl from C7 to C24, R" is H or R', R'" is alkylene from C1 to C24, arylene from C6 to C24, alkarylene from C7 to C24, or aralkylene from C7 to C24, m is 1 to 7, and n is 1 to 20. The article is exposed to gamma radiation; it yellows less after irradiation than it otherwise would.
    • 公开了一种制备无菌制品的方法。 从其中加入具有以下通式的稳定剂的聚合物制备制品:其中每个A独立地选自E,OR,SR和CO-R,并且可以连接芳环以形成另外的环,E是 R或R(OCH 2 R“CH)n,G是E,CO-R,-C(E)HOR,C(OE)(H)-OR,-C(E)(R”)R“ -C(E)(R“)-R'” - CO-OR,C(OE)(R“) - E'”COOR,-C(OE)R“ ,或-C(OE)R 2,J为A,每个R独立地选自H,R',R'“OR',R”COOR',R“C(OR”)R“或R' “C(OR”)R“”OR“,每个R'独立地选自C 1至C 24的烷基,C 6至C 24的芳基,C 7至C 24的烷芳基和C 7至C 24的芳烷基,R”为H或R ',R'是C1至C24的亚烷基,C6至C24的亚芳基,C7至C24的亚烷基,C7至C24的亚芳基,m为1-7,n为1至20.该物品暴露于γ 放射线;辐射后黄色较其它方式少。