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1. 发明申请

WO2002060498A1 LUMEN OCCLUDERS MADE FROM THERMODYNAMIC MATERIALS 审中-公开
标题翻译：来自热力学材料的LUMEN OCCLUDERS
公开(公告)号：WO2002060498A1
公开(公告)日：2002-08-08
申请号：PCT/US2002/002398
申请日：2002-01-28
申请人： NUMED/TECH, LLC
发明人： FELDMAN, Tatyana , WANG, Wei
IPC分类号： A61L15/00
CPC分类号： A61L31/14 , A61B17/12022 , A61B17/12099 , A61B17/12131 , A61B17/1219 , A61B2017/00867 , A61B2017/00871 , A61F11/08 , A61L31/125 , A61L31/129 , A61L2400/16 , A61L2430/36 , C08L33/04 , C08L83/04
摘要： Disclosed are occluders and methods of their use. The occluders comprise shape-memory polymeric materials which, when heated above their crystalline melting temperatures, may be deformed from a first configuration into a second configuration. The occluder is then held in the deformed shape until it cools to a temperature below its crystalline melting temperature (T m ) whereby it holds the deformed shape of the second configuration by virtue of the recrystallization of the polymeric occluder material. Upon reheating the occluder above its T m' the occluder will resume its original shape. In this manner, an occluder which has been deformed to reduce its diameter may be inserted into and positioned within a target lumen in the body and then allowed to warm to body temperature whereby it resumes its original diameter and results in the occlusion of the lumen. The occluders, according to preferred embodiments, may be used for reversible sterilization of mammals, among other surgical and non-surgical uses.
摘要翻译：公开了封堵器及其使用方法。闭塞器包括形状记忆聚合材料，当被加热到高于它们的结晶熔融温度时，其可以从第一构型变形成第二构型。然后将封堵器保持在变形形状中，直到其冷却到低于其结晶熔融温度（Tm）的温度，由此通过聚合物封闭材料的再结晶，其保持第二构型的变形形状。封堵器重新加热超过其Tm'时，封堵器将恢复其原始形状。以这种方式，已经变形以减小其直径的封堵器可以插入并定位在体内的目标腔中，然后被允许温热到体温，从而恢复其原始直径并导致内腔闭塞。根据优选实施例，封堵器可以用于哺乳动物的可逆灭菌，以及其它手术和非手术用途。

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