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1. 发明申请

WO2009131865A1 A SYSTEM TO MONITOR EJECTION TIME AND QT INTERVAL TO ALERT PATIENTS BEFORE SYNCOPAL EVENTS 审中-公开
标题翻译：监测病人出院时间和间隔时间间隔的系统
公开(公告)号：WO2009131865A1
公开(公告)日：2009-10-29
申请号：PCT/US2009/040414
申请日：2009-04-14
申请人： MEDTRONIC, INC. , CORBUCCI, Giorgio , BOUTE, Willem , SCHOLTEN, Patrick , SMIT, Josephus
发明人： CORBUCCI, Giorgio , BOUTE, Willem , SCHOLTEN, Patrick , SMIT, Josephus
IPC分类号： A61N1/365 , A61B5/0452
CPC分类号： A61N1/365 , A61B5/0452 , A61N1/36535 , A61N1/36542 , A61N1/36585
摘要： An implantable medical device predicts syncope based on detecting a change in ejection time. A physiological signal is sensed that is responsive to mechanical changes associated with the cardiac ejection phase. A time interval corresponding to cardiac ejection time is detected from the physiological signal. A sudden change in the time interval is used as a predictor of syncope and causes a patient alert to be generated in response to the detected change.
摘要翻译：可植入医疗装置基于检测喷射时间的变化来预测晕厥。感测到响应于与心脏喷射阶段相关的机械变化的生理信号。从生理信号检测与心脏喷射时间对应的时间间隔。使用时间间隔的突然变化作为晕厥的预测因子，并且响应于检测到的变化而产生患者警报。

2. 发明申请

WO2008014459A2 PRIORITIZED MULTICOMPLEXOR SENSING CIRCUIT 审中-公开
标题翻译：优化的多元复合传感器电路
公开(公告)号：WO2008014459A2
公开(公告)日：2008-01-31
申请号：PCT/US2007/074605
申请日：2007-07-27
申请人： MEDTRONIC, INC. , ROUW, Mattias , SCHOLTEN, Patrick
发明人： ROUW, Mattias , SCHOLTEN, Patrick
CPC分类号： A61N1/3704 , A61B5/04085
摘要： An implantable medical device having a prioritized multiplexor sensing circuit used for monitoring the condition or status of a patient. The device includes patient parameter sensors, such as electrodes, that are monitored for indications of significant events. Sensors indicating the presence of significant events may then be monitored more often than the other sensors.
摘要翻译：具有优先化的多路复用器感测电路的可植入医疗设备用于监测患者的状况或状态。该设备包括患者参数传感器，例如电极，其被监测以显示重大事件。指示存在重大事件的传感器可能比其他传感器更经常被监测。

3. 发明申请

WO2009142975A1 FALL DETECTION ALGORITHM UTILIZING A THREE-AXIS ACCELEROMETER 审中-公开
标题翻译：使用三轴加速度计的失效检测算法
公开(公告)号：WO2009142975A1
公开(公告)日：2009-11-26
申请号：PCT/US2009/043762
申请日：2009-05-13
申请人： MEDTRONIC, INC. , SCHOLTEN, Patrick , KERVER, Harry, Bernardus-Antonius
发明人： SCHOLTEN, Patrick , KERVER, Harry, Bernardus-Antonius
IPC分类号： A61B5/11
CPC分类号： A61B5/1117 , A61B5/0031
摘要： A three-axis accelerometer signal is used in a medical device for detecting that a patient has fallen. The accelerometer signal is sampled at a low sampling rate for determining a patient position. The accelerometer signal is sampled at a high sampling rate for determining an acceleration magnitude in response to determining the patient position. The patient position and acceleration magnitude are used to detect that a patient has fallen.
摘要翻译：在用于检测患者已经下降的医疗装置中使用三轴加速度计信号。以低采样率采样加速度计信号以确定患者位置。响应于确定患者位置，以高采样率采样加速度计信号以确定加速度幅度。患者位置和加速度大小用于检测患者是否已经下降。

4. 发明申请

WO2010005788A2 IMPLANTABLE MEDICAL DEVICE ORIENTATION DETECTION UTILIZING AN EXTERNAL MAGNET AND A 3D ACCELEROMETER SENSOR 审中-公开
标题翻译：使用外部磁体和三维加速度传感器的可移植医疗设备方向检测
公开(公告)号：WO2010005788A2
公开(公告)日：2010-01-14
申请号：PCT/US2009/048439
申请日：2009-06-24
申请人： MEDTRONIC, INC. , SCHOLTEN, Patrick , VAN DAM, Peter, M.
发明人： SCHOLTEN, Patrick , VAN DAM, Peter, M.
IPC分类号： A61N1/00 , A61B5/05
CPC分类号： A61N1/36542 , A61B5/0031 , A61B5/061 , A61B5/11 , A61B2562/0219
摘要： A method and device for detecting the implanted orientation of an implantable medical device (IMD) in a patient. IMD includes an accelerometer for measuring acceleration signals in three orthogonal directional axes. A y-axis orientation of IMD is determined from the measured accelerometer signals using a gravitational force analysis. IMD includes a magnetic sensor that senses a varying magnetic field exerted on the magnetic sensor from an external magnet moved along a medial-lateral direction with respect to IMD. The z-axis orientation of IMD is determined from the location of the external magnet where the magnetic field exerted on the magnetic sensor is greatest. Based on a known relationship between the accelerometer and magnetic sensor, an orthogonal transformation calculation is performed on the y-axis and z-axis orientations to yield the x-axis orientation. The implanted orientation of IMD with respect to the patient is thus known and used to compensate accelerometer measurements.
摘要翻译：一种用于检测患者体内植入式医疗装置（IMD）的植入取向的方法和装置。 IMD包括用于在三个正交方向轴上测量加速度信号的加速度计。使用重力分析从所测量的加速度计信号确定IMD的y轴取向。 IMD包括磁传感器，其感测从相对于IMD沿着内侧方向移动的外部磁体施加在磁性传感器上的变化的磁场。 IMD的z轴取向是由施加在磁传感器上的磁场最大的外部磁体的位置确定的。基于加速度计和磁传感器之间的已知关系，对y轴和z轴取向执行正交变换计算以产生x轴取向。因此，IMD相对于患者的植入取向是已知的并且用于补偿加速度计测量。

5. 发明申请

WO2009114303A1 IMPLANTABLE MEDICAL DEVICE WITH PATIENT INPUT MECHANISM 审中-公开
标题翻译：具有患者输入机制的可植入医疗器械
公开(公告)号：WO2009114303A1
公开(公告)日：2009-09-17
申请号：PCT/US2009/035631
申请日：2009-03-02
申请人： MEDTRONIC, INC. , SCHOLTEN, Patrick
发明人： SCHOLTEN, Patrick
IPC分类号： A61B5/00 , A61B5/0452 , A61B5/07 , A61N1/37 , A61N1/375 , A61N1/372
CPC分类号： A61B5/0031 , A61B5/0006 , A61B5/04325 , A61B5/7232 , A61N1/3702 , A61N1/37217 , A61N1/3756 , G06F19/00
摘要： An implantable loop recorder (ILR) is subcutaneously implantable to record cardiac data. The ILR includes a patient activation mechanism whereby the patient can input commands to the ILR without using an external device. The patient activation mechanism may be a subcutaneous switch disposed on an outer portion of the ILR or a motion sensor that senses tapping of the device as an input. The patient input will direct the device to store data, telemeter data, or send a message summoning an emergency response. The ILR has distance telemetry capabilities so that a telemetered message is wirelessly transmitted to an external device which then relays the message to a remote location.
摘要翻译：可植入环路记录器（ILR）可植入人造记录心脏数据。 ILR包括患者激活机制，由此患者可以在不使用外部设备的情况下向ILR输入命令。患者激活机构可以是设置在ILR的外部部分上的皮下开关或感测装置的敲击作为输入的运动传感器。患者输入将指示设备存储数据，遥测数据或发送召回应急响应的消息。 ILR具有距离遥测能力，使得遥测消息无线地传输到外部设备，然后将消息中继到远程位置。

6. 发明申请

WO2004096346A2 FORM ANALYSIS TO DETECT EVOKED RESPONSE 审中-公开
标题翻译：形式分析以检测响应的响应
公开(公告)号：WO2004096346A2
公开(公告)日：2004-11-11
申请号：PCT/US2004/012094
申请日：2004-04-19
申请人： MEDTRONIC, INC. , VAN OORT, Geeske , OOSTERHOFF, Peter , DE BRUYN, Henricus, W. M. , SCHOLTEN, Patrick
发明人： VAN OORT, Geeske , OOSTERHOFF, Peter , DE BRUYN, Henricus, W. M. , SCHOLTEN, Patrick
IPC分类号： A61N1/00
CPC分类号： A61B5/0452 , A61N1/371
摘要： Method and device for determining capture status of a heart chamber that receives a pulse from an implantable pulse generator (IPG). Signal processing can be used to improve the reliability of capture detection by transforming the sensed response signal into a set of morphological characteristics. Analysis of selected morphological characteristics serves to distinguish signals indicative of capture from signals indicative of loss of capture.
摘要翻译：用于确定从可植入脉冲发生器（IPG）接收脉冲的心室的捕获状态的方法和装置。信号处理可用于通过将感测到的响应信号转换成一组形态特征来提高捕获检测的可靠性。所选形态特征的分析用于将表示捕获的信号与表示捕获损失的信号区分开来。

7. 发明申请

WO2019231696A1 BODY AND BODY PART ORIENTATION AND POSTURE MONITORING 审中-公开
公开(公告)号：WO2019231696A1
公开(公告)日：2019-12-05
申请号：PCT/US2019/032570
申请日：2019-05-16
申请人： MEDTRONIC, INC.
发明人： LEE, Brian B. , SCHOLTEN, Patrick
IPC分类号： A61B5/11
摘要： Techniques for determining a patient's orientation using an accelerometer that is part of a medical device carried by or implanted in a patient. The medical device may use the accelerometer to determine the orientation of the medical device with respect to gravity. When the medical device is fixed in a known orientation on the patient, the medical device may perform a calculation to determine the orientation of a patient. To simplify calculations and reduce power consumption, the device may calculate an inner product (dot product) multiplication between the orientation vector of the medical device and one or more known reference templates. In some examples, the medical device may determine which reference template is closest to the orientation vector, based on the dot product. In other examples, the medical device may determine one or more body part angles for the patient, based on dot product.

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