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1. 发明申请

WO2002068050A1 LEAD UP-SIZING SLEEVE 审中-公开
标题翻译： LEAD UP SIZE SLEEVE
公开(公告)号：WO2002068050A1
公开(公告)日：2002-09-06
申请号：PCT/US2002/006459
申请日：2002-02-21
申请人： MEDTRONIC, INC.
发明人： SOMMER, John, L. , HINE, Douglas, S. , BJORKLUND, Vicki, L. , BELDEN, Elisabeth, L. , CLEMENS, William, J. , RIES, Andrew, J. , HONECK, Jordan, D. , SCHRODER, Harry
IPC分类号： A61N1/375
CPC分类号： A61N1/3752
摘要： An improved connection system for coupling a device such as a pacemaker (121), cardioverter, defibrillator, nerve stimulator, muscle stimulator, implantable monitor or other medical device to a medical lead (190) is disclosed. The connection system includes a coupling member (100) designed to couple to the proximal end of the lead. This coupling member, which includes an inner lumen sized to form a press fit around the proximal end of the lead body, may be of a generally tubular construction. This coupling member includes connector means to enable a connector pin at the proximal end of the lead to mechanically and electrically couple to a device. The connector means may further include means for coupling both mechanically and electrically to a ring connector on the proximal end of a multi-polar lead. An insertion member may (110) also be provided to allow the lead to be more easily inserted within the inner lumen of the coupling member.
摘要翻译：公开了一种用于将诸如起搏器（121），心脏转复器，除颤器，神经刺激器，肌肉刺激器，可植入监视器或其他医疗装置的装置耦合到医疗引线（190）的改进的连接系统。连接系统包括设计成耦合到引线的近端的耦合构件（100）。该联接构件包括尺寸适于形成围绕引线主体的近端的压配合的内腔，其可以是大致管状的结构。该联接构件包括连接器装置，以使引线的近端处的连接器销能够机械地和电气地耦合到装置。连接器装置还可以包括用于将机械和电耦合到多极引线的近端上的环形连接器的装置。还可以设置插入构件（110）以允许引线更容易地插入联接构件的内腔内。

2. 发明申请

WO2019183512A1 VFA CARDIAC RESYNCHRONIZATION THERAPY 审中-公开
公开(公告)号：WO2019183512A1
公开(公告)日：2019-09-26
申请号：PCT/US2019/023642
申请日：2019-03-22
申请人： MEDTRONIC, INC.
发明人： YANG, Zhongping , ANDERSON, Thomas, A. , COLIN, Brian, P. , CLEMENS, William, J. , GHOSH, Subham , GILLBERG, Jeffrey, M. , VERBEEK, Maurice, T.I. , CAMPS, Toine , KORNET, Lilian , STEGEMANN, Berthold , RUTTEN, Jean
IPC分类号： A61N1/375 , A61N1/05 , A61N1/368
摘要： VfA cardiac therapy uses an implantable medical device or system. The implantable medical device includes a tissue-piercing electrode implanted in the basal and/or septal region of the left ventricular myocardium of the patient's heart from the triangle of Koch region of the right atrium through the right atrial endocardium and central fibrous body. The device may include a right atrial electrode, a right atrial motion detector, or both. The device may be implanted completely within the patient's heart or may use one or more leads to implant electrodes in the patient's heart. The device may be used to provide cardiac therapy, including single or multiple chamber pacing, atrioventricular synchronous pacing, asynchronous pacing, triggered pacing, cardiac resynchronization pacing, or tachycardia-related therapy. A separate medical device may be used to provide some functionality for cardiac therapy, such as sensing, pacing, or shock therapy.

3. 发明申请

WO2016065345A1 CORONARY SINUS MEDICAL ELECTRICAL LEAD 审中-公开
标题翻译：冠心病医用电线
公开(公告)号：WO2016065345A1
公开(公告)日：2016-04-28
申请号：PCT/US2015/057251
申请日：2015-10-23
申请人： MEDTRONIC, INC.
发明人： SOMMER, John, L. , CLEMENS, William, J. , FRANKE, Linda, L.
IPC分类号： A61N1/00
CPC分类号： A61N1/056 , A61N1/3627 , A61N1/3686 , A61N2001/0585
摘要： One embodiment of the invention comprises an intravenous medical electrical lead that includes an elongated lead body. The elongated lead body comprises a length between a proximal end and a shaped distal end, The lead body includes a longitudinal axis extending between the proximal end and the shaped distal end. The lead body has an outer circumference with a set of electrodes circumferentially spaced apart. Each electrode includes an electrically active portion and an insulated portion at an outer circumference of the electrode. If the lead body rotates within the delivery catheter, the lead body is configured to rotate back into a position such that the electrically active portion of a set of electrodes faces myocardial tissue when exiting the guide catheter while the insulated portion of electrode are diametrically opposed to neural tissue such as the phrenic nerve.
摘要翻译：本发明的一个实施例包括静脉内医疗电引线，其包括细长引线体。细长的引线体包括在近端和成形的远端之间的长度。引线主体包括在近端和成形的远端之间延伸的纵向轴线。引线体具有外周，其周向间隔开一组电极。每个电极在电极的外周包括电活性部分和绝缘部分。如果引导体在输送导管内旋转，则引线体被配置成旋转回一个位置，使得一组电极的电活性部分在离开引导导管时面向心肌组织，同时电极的绝缘部分直径相对于神经组织如膈神经。

4. 发明申请

WO2009121047A1 IMPLANTABLE MEDICAL ELECTRICAL LEAD BODIES PROVIDING IMPROVED ELECTRODE CONTACT 审中-公开
标题翻译：提供改进的电极接触的医疗电气引线体
公开(公告)号：WO2009121047A1
公开(公告)日：2009-10-01
申请号：PCT/US2009/038720
申请日：2009-03-30
申请人： MEDTRONIC, INC. , CLEMENS, William, J. , WERNER, Nicole, L. , LOCH, Deborah, A. , HINE, Douglas, S. , HESS, Douglas, N. , PFEIFFER, Carla, C. , BAXTER, Walton, W.
发明人： CLEMENS, William, J. , WERNER, Nicole, L. , LOCH, Deborah, A. , HINE, Douglas, S. , PFEIFFER, Carla, C. , BAXTER, Walton, W.
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N2001/0585
摘要： A distal section of an implantable medical electrical lead body includes a pair of pre-formed arcuate segments between which an approximately straight segment extends. The approximately straight segment includes a first portion extending distally from a first of the pair pre-formed arcuate segments, a second portion extending from the first portion, a third portion extending from the second to a second of the pair pre-formed arcuate segments. An electrode is coupled to the second portion of the approximately straight segment, and the adjacent first portion has a stiffness which is less than that of the first of the pair pre-formed arcuate segments and preferably less than the stiffness of the third portion, so that, when the distal section of the lead body is implanted, for example, within a cardiac vein, the lead buckles to bring the electrode into closer contact with surrounding tissue.
摘要翻译：植入式医疗电引线主体的远端部分包括一对预先形成的弧形段，大致直线段延伸在该弧形段之间。大致直的部分包括从第一对预成形弧形段向远端延伸的第一部分，从第一部分延伸的第二部分，从该对预成形弧形段的第二部分延伸到第二部分的第三部分。电极耦合到大致直线段的第二部分，并且相邻的第一部分的刚度小于预先形成的一对弓形段中的第一部分的刚度，并且优选地小于第三部分的刚度，因此当引线体的远侧部分植入心脏静脉内时，引线带扣使电极与周围的组织更接近。

5. 发明申请

WO2002058465A3 PERFUSION LEAD 审中-公开
公开(公告)号：WO2002058465A3
公开(公告)日：2002-08-01
申请号：PCT/US2001/049226
申请日：2001-12-19
申请人： MEDTRONIC, INC.
发明人： CLEMENS, William, J. , HESS, Douglas, N. , SOMMERS, John, L. , SOYKAN, Orhan
IPC分类号： A61N1/05
摘要： A medical electrical lead (10) including an inflatable member (12) at a distal tip section, and a system of use, are disclosed. The inflation member is adapted to engage the walls of a cardiac vein or coronary artery to occlude the vessel. According to one aspect of the invention, the inflation member is formed of a bio-absorbable material. In another embodiment, the inflation member is a micro-porous material. The lead of the current invention may include a port located distal to the inflation member is in the inflated state. This allows a fluoroscopic image of a patient's vascular system to be obtained while the lead is in place within a vessel. A perfusion lumen may be provided to allow a partial flow of blood to continue around the inflation member (18) when the inflation member is occluding a vessel. In one embodiment, lead is provided with a lumen for receiving a stiffening menber such as a stylet (64) to aid in lead is placement. According to one method of using the current invention, inflation member may be inflated after the lead is placed at a desired implant site to provide a temporary fixation mechanism during withdrawal of the stiffening member and/or a guide catheter or sheath used to place the lead at the implant site. This temporary fixation mechanism may also be employed to retain a desired lead location while thresholds are obtains. The inflation member may be retained in an inflated state for a longer predetermined period of time until tissue in-growth begins to occur around the lead.

6. 发明申请

WO2016069415A1 CORONARY SINUS MEDICAL ELECTRICAL LEAD 审中-公开
标题翻译：冠心病医用电线
公开(公告)号：WO2016069415A1
公开(公告)日：2016-05-06
申请号：PCT/US2015/057253
申请日：2015-10-23
申请人： MEDTRONIC, INC.
发明人： SOMMER, John, L. , CLEMENS, William, J. , FRANKE, Linda, L.
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/3627 , A61N1/3686 , A61N2001/0585
摘要： The present invention may comprise an improvement to the prior art leads as disclosed above. In a preferred embodiment, the invention comprises an medical electrical lead that includes an elongated lead body. The elongated lead body comprises a length between a proximal end and a curved distal end, the lead body defining a Iongitudinal axis extending between the proximal end and the distal end. The lead body having an outer circumference and provided with a set of electrodes circumferentially spaced apart. Each electrode includes an electrically active portion and an insulated portion at an outer circumference of the electrode along a first longitudinal plane and along a second Iongitudinal plane diametrically opposed to the first longitudinal plane are insulated electrodes. Each electrode is configured to include a guide aid to engage with a non-conductive housing.
摘要翻译：本发明可以包括对如上所公开的现有技术的引线的改进。在优选实施例中，本发明包括包括细长引线体的医用电引线。细长引线体包括在近端和弯曲远端之间的长度，引线主体限定在近端和远端之间延伸的纵向轴线。引线体具有外圆周并且设置有周向间隔开的一组电极。每个电极包括电活性部分，并且沿着第一纵向平面并且沿着与第一纵向平面直径相对的第二纵向平面在电极的外周处的绝缘部分是绝缘电极。每个电极被构造成包括导向辅助件以与非导电壳体接合。

7. 发明申请

WO2004060478A1 A CATHETER-DELIVERED CARDIAC LEAD 审中-公开
标题翻译：一个传送带的领导
公开(公告)号：WO2004060478A1
公开(公告)日：2004-07-22
申请号：PCT/US2003/039744
申请日：2003-12-15
申请人： MEDTRONIC, INC.
发明人： CLEMENS, William, J. , RUFF, Michael, A. , BELDEN, Elisabeth, L. , MCHENRY, Brian, T. , LASKE, Timothy, G. , FREIBORG, Michael, L. , HESS, Douglas, N. , WILLIAMS, Terrell, M. , BUCHEGER, Mark, B. , BONNER, Matthew, D.
IPC分类号： A61N1/04
CPC分类号： A61N1/056 , A61N2001/058
摘要： A lead for delivering electrical signals to and/or receive electrical signals from a human heart that includes a solid inner conductor, and a fixation device having a titanium nitride coated surface and electrically coupled to the inner conductor. A steroid is applied to the titanium nitride surface of the fixation device, and at least one layer of insulation is positioned around the inner conductor. A conductive coil is positioned around and is insulated from the inner conductor, an electrode ring electrically coupled to the conductive coil is positioned around and is electrically isolated from the inner conductor, and an insulating spacer is positioned between and electrically isolates the ring electrode and the fixation device.
摘要翻译：用于将电信号传递到和/或接收来自包括实心内导体的人心脏的电信号的引线，以及具有氮化钛涂覆表面并电耦合到内导体的固定装置。将类固醇施加到固定装置的氮化钛表面，并且至少一层绝缘体围绕内部导体定位。导电线圈定位在内导体周围并与内导体绝缘，电耦合到导电线圈的电极环位于内导体周围并与内导体电隔离，并且绝缘间隔件位于电极之间并电隔离环形电极和固定装置

8. 发明申请

WO2003030988A3 LEAD SYSTEM FOR PROVIDING ELECTRICAL STIMULATION TO THE BUNDLE OF HIS 审中-公开
公开(公告)号：WO2003030988A3
公开(公告)日：2003-04-17
申请号：PCT/US2002/033662
申请日：2002-10-07
申请人： MEDTRONIC,INC.
发明人： ALINDER, Jason , CASAVANT, David, A. , HESS, Douglas, N. , GRENZ, David, A. , FREIBORG, Mike , CLEMENS, William, J. , RUFF, Michael, A.
IPC分类号： A61N1/05
摘要： Methods and endocardial screw-in leads for enabling provision of electrical stimulation to the heart, particularly the His Bundle in the intraventricular septal wall. An endocardial screw-in lead having a distal end coupled to a retractable fixation helix wherein a distal portion of the fixation helix extends beyond the lead distal end when the fixation helix is fully retracted or partially extended is positioned in proximity to the His Bundle in the septal wall. The lead body is rotated to attach the distal portion of the fixation helix into the septal wall. The fixation helix is rotated with respect to the lead body to fully extend the fixation helix so that a portion of the fixation helix is in proximity to the His Bundle, enabling provision of electrical stimulation to the His Bundle and/or to sense electrical signals of the heart traversing the His Bundle through the fixation helix.

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