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    • 3. 发明申请
    • ULTRASONIC METHOD TO DETERMINE BONE PARAMETERS
    • 超声方法确定骨参数
    • WO2006119511A2
    • 2006-11-09
    • PCT/US2006017858
    • 2006-05-04
    • LUNA INNOVATIONS INCLYNCH JOHN EHEYMAN JOSEPH SMCKENNA MARK
    • LYNCH JOHN EHEYMAN JOSEPH SMCKENNA MARK
    • A61B8/00
    • A61B8/0875A61B8/0808A61B8/485
    • A method of measuring bone strength under dynamic loading is provided using an ultrasonic probe wave sensor to sense a low-frequency pump wave and an ultrasonic probe wave implemented to the bone. The bone is cyclically loaded with compressional and rarefactional pump waves, and probed with the probe wave that is timed according to the pump wave to determine the wave velocity of the probe wave. Bone strength is interpreted by measuring wave velocity changes during the pump wave cycles. Ultrasonic velocity derivatives are used to determine bone third-order (nonlinear) elastic constants that are linked to bone strength. High-resolution second-order (linear) elastic constants are provided through measurement of absolute phase velocity. A pulsed phase lock loop is locked at intervals as the probe wave phase is modulated over 360 degrees providing probe wave harmonic numbers that are correlated with the pump wave frequency to determine the probe wave velocity.
    • 使用超声波探头波传感器来测量在动态载荷下测量骨强度的方法,以感测实施到骨骼上的低频泵浦波和超声探针波。 骨骼循环加载有压缩和稀疏的泵浦波,并用根据泵波定时的探针波探测以确定探针波的波速。 通过在泵波周期期间测量波速度变化来解释骨强度。 超声波速度导数用于确定与骨强度相关的骨三阶(非线性)弹性常数。 通过测量绝对相速度提供高分辨率二阶(线性)弹性常数。 脉冲相位锁定环被间隔锁定,因为探测波相位被调制到360度以上,提供与泵浦波频率相关的探测波谐波数,以确定探测波速度。