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    • 2. 发明申请
    • FUNCTIONALIZED TISSUE MATRICES
    • 功能组织矩阵
    • WO2013162997A1
    • 2013-10-31
    • PCT/US2013/037133
    • 2013-04-18
    • LIFECELL CORPORATION
    • OWENS, RickLIU, Zhigang
    • A61L27/36
    • A61K35/12A61K31/7088A61K38/16A61K38/4886A61K38/50A61K45/06A61L27/362A61L27/3687
    • Disclosed herein are tissue treatment products that have been bound to at least one chelating agent. Also disclosed are tissue treatment products that have been functionalized with at least one metal and/or at least one metal-binding protein. The tissue treatment products can have antimicrobial properties and/or factors that promote or enhance native ceil migration, proliferation, and/or revascularization after implantation into a subject. Also disclosed are methods of making and using the tissue treatment products. The tissue treatment products can be implanted into a tissue in need of repair, regeneration, healing, treatment, and/or alteration and can promote or enhance native cell migration, proliferation, and/or revascularization.
    • 本文公开了已结合至少一种螯合剂的组织处理产品。 还公开了已经用至少一种金属和/或至少一种金属结合蛋白官能化的组织处理产品。 组织处理产品可以具有在植入受试者之后促进或增强天然细胞迁移,增殖和/或血运重建的抗微生物特性和/或因素。 还公开了制备和使用组织处理产品的方法。 组织处理产品可以植入需要修复,再生,愈合,治疗和/或改变的组织中,并可以促进或增强天然细胞迁移,增殖和/或血运重建。