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    • 6. 发明申请
    • A SKIN TREATMENT DEVICE
    • 皮肤处理装置
    • WO2017097923A1
    • 2017-06-15
    • PCT/EP2016/080300
    • 2016-12-08
    • KONINKLIJKE PHILIPS N.V.
    • VARGHESE, BabuBARAGONA, MarcoPALERO, Jonathan, AlambraJURNA, MartinHORTON, Margaret, RuthEZERSKAYA, Anna
    • A61B18/20A61N5/06
    • A61B18/203A61B2018/0047A61B2018/2035A61B2018/2266A61N5/0616A61N2005/067
    • The invention relates to a skin treatment device (10) for fractional treatment of the skin (100) of a human being. A radiation source (5) emits a multi-mode laser beam (20) with a superposition (23) of mutually different higher-order laser modes. The multi-mode laser beam is configured by said superposition of different laser modes to simultaneously cause a first plurality of high-intensity zones, where the thermal threshold (TC) for collagen denaturation for the treatment zone (50) of the skin is at least reached, and a second plurality of low-intensity zones where the thermal threshold (TF) for fibroblast stimulation for the treatment zone of the skin is at least reached. This is advantageous for obtaining a skin treatment device with a simple and therefore low-cost fractional laser skin treatment system for combined collagen denaturation and fibroblast stimulation. The skin treatment device is based on non-uniform laser radiation in the form of the multi-mode laser beam.
    • 本发明涉及一种用于对人的皮肤(100)进行分级处理的皮肤处理装置(10)。 辐射源(5)发射具有相互不同的高阶激光模式的叠加(23)的多模式激光束(20)。 通过所述不同激光模式的叠加来配置多模式激光束以同时引起第一多个高强度区域,其中用于皮肤的治疗区域(50)的胶原变性的热阈值(TC)至少为 以及第二多个低强度区域,其中至少达到用于皮肤的治疗区域的成纤维细胞刺激的热阈值(TF)。 这对于获得具有用于组合胶原蛋白变性和成纤维细胞刺激的简单且因此低成本的分数激光皮肤处理系统的皮肤处理装置是有利的。 皮肤处理装置基于多模式激光束形式的非均匀激光辐射。
    • 8. 发明申请
    • DEVICE AND METHOD FOR NON-INVASIVE TREATMENT OF SKIN USING LASER LIGHT
    • 使用激光照射非皮肤治疗皮肤的装置和方法
    • WO2015110273A1
    • 2015-07-30
    • PCT/EP2015/050018
    • 2015-01-04
    • KONINKLIJKE PHILIPS N.V.
    • VARGHESE, BabuJURNA, MartinPALERO, Jonathan AlambraHORTON, Margaret RuthZEITOUNY, MounirVERHAGEN, Rieko
    • A61B18/20A61B18/00
    • A61B18/203A61B17/54A61B2017/00747A61B2018/00452A61B2018/00458A61B2018/0047A61B2018/00476A61B2018/00714A61B2018/00791A61B2018/00803A61B2018/2035A61N5/0616A61N2005/067
    • The invention relates generally to the treatment of skin using laser light, and more particularly to a non-invasive device and method for such treatment. During skin treatments, heating of the epidermis is undesired because it may cause discomfort for the person being treated, adverse skin reactions and unwanted changes in skin pigment. The invention provides a laser treatment beam having a first 22a and a second 22b beam region of non-zero light intensity disposed at a periphery of a transverse cross-section of the beam, and a third beam region 22c, arranged between the first 22a and the second 22b beam region, of lower light intensity than said non-zero light intensity. The treatment beam 22 exits the device 10 along its optical treatment axis 13. As the treatment beam 22 passes through an outer layer of the skin to the focal spot 25 along the optical treatment axis (13), the extent of the third beam region 22c is predetermined and/or controlled so as to provide a corresponding third skin region 23c in the outer skin layer16, arranged between the first 23a and the second skin region 23b, and the lower light intensity of the third beam region is predetermined and/or controlled to provide a maximum temperature during a pulse of the laser treatment beam with in the third skin region 23c which is lower than the maximum temperatures during said pulse of the laser treatment beam within the first 23a and the second 23b skin region. The light source 20 is configured and arranged to provide, in use, a pulse duration of the pulse of the laser treatment beam which is longer than the thermal relaxation time of the first 23a and the second 23b skin region. By predetermining and/or controlling the dimensions of the third skin region 23c, a suitably dimensioned heat sink is created, centrally located within the region being heated by the laser treatment beam, and used to avoid temperature hot spots in the outer layers of the skin.
    • 本发明一般涉及使用激光治疗皮肤,更具体地涉及用于这种治疗的非侵入性装置和方法。 在皮肤治疗期间,不希望加热表皮,因为它可能引起被治疗者的不适,皮肤反应不良和皮肤色素的不希望的变化。 本发明提供了一种激光处理光束,其具有布置在光束的横截面周边的非零光强度的第一22a和第二22b光束区域,以及第三光束区域22c,布置在第一光束区域22a和 第二22b光束区域,比所述非零光强度低的光强度。 处理束22沿其光学处理轴线13离开装置10.当处理束22沿着光学处理轴线(13)穿过皮肤的外层至焦点25时,第三束区域22c的程度 被预先确定和/或控制,以便在第一皮肤区域23b和第二皮肤区域23b之间的外皮层16中提供相应的第三皮肤区域23c,并且第三束区域的较低的光强度被预先确定和/或控制 以在第三皮肤区域23c内的激光治疗光束的脉冲期间提供比在第一23a和第二23b皮肤区域内的激光治疗束的所述脉冲期间的最大温度低的最大温度。 光源20被配置和布置成在使用中提供比第一23a和第二23b皮肤区域的热松弛时间长的激光治疗束的脉冲的脉冲持续时间。 通过预先确定和/或控制第三皮肤区域23c的尺寸,产生适当尺寸的散热器,居中地位于由激光治疗束加热的区域内,并用于避免皮肤外层中的温度热点 。
    • 9. 发明申请
    • A SKIN TREATMENT DEVICE FOR MULTI-PHOTON BASED SKIN TREATMENT
    • 一种用于多光子皮肤治疗的皮肤治疗装置
    • WO2015063245A1
    • 2015-05-07
    • PCT/EP2014/073407
    • 2014-10-31
    • KONINKLIJKE PHILIPS N.V.
    • VARGHESE, BabuVERHAGEN, RiekoJURNA, MartinPALERO, Jonathan Alambra
    • A61B18/20
    • A61B18/203A61B18/20A61B2018/0047A61B2018/00696A61N2005/073
    • The invention provides a non-invasive skin treatment device (100) comprising: a light source (10) constructed and configured for generating linearly polarized probe light (12) and linearly polarized treatment light (22), a polarization modulator (30) constructed and configured for controlling a polarization direction of the probe light and a polarization direction of the treatment light, a polarization sensitive sensor (40) constructed and configured for sensing a level of depolarization of the probe light by sensing an intensity of back-scattered probe light (42) from the target position (210) in a predefined polarization direction of the polarization sensitive sensor, and a controller (60) being configured for scanning the polarization direction of the probe light over a predefined range while receiving the measurement signal (Sm) and for selecting an optimum polarization (P1) direction for which the depolarization of the probe light is at a minimum. The invention further provides a computer program product for controlling the skin treatment device.
    • 本发明提供了一种非侵入性皮肤治疗装置(100),包括:构造和配置用于产生线偏振探测光(12)和线性偏振处理光(22)的光源(10),构造的偏振调制器(30)和 被配置为用于控制探测光的偏振方向和处理光的偏振方向;偏振敏感传感器(40),被构造和配置为通过感测反向散射探测光的强度来感测探测光的去极化水平( 42)在偏振敏感传感器的预定极化方向上从目标位置(210)移除;以及控制器(60),被配置为在接收测量信号(Sm)的同时在预定范围内扫描探测光的偏振方向,以及 用于选择探针光的去极化最小的最佳极化(P1)方向。 本发明还提供了一种用于控制皮肤治疗装置的计算机程序产品。
    • 10. 发明申请
    • NON-INVASIVE TREATMENT OF SKIN USING LASER LIGHT.
    • 使用激光照射非侵入性皮肤治疗。
    • WO2014132146A1
    • 2014-09-04
    • PCT/IB2014/058515
    • 2014-01-24
    • KONINKLIJKE PHILIPS N.V.
    • VARGHESE, BabuVERHAGEN, Rieko
    • A61N5/06A61B18/20
    • A61N5/0616A61B18/203A61B2018/00452A61N2005/067A61N2005/073
    • The invention provides a non-invasive device for treatment of skin (30) using laser light, the device comprising: an optical system (10) having a laser light source (20) for generating a light beam (21), an opening (13) allowing the light beam (21) to exit the device, and an optical component (12) configured to radially polarize the light beam (21) exiting the device; the optical system (10) being configured such that, in use, the exiting light beam (21) impinges on the outer surface of the skin (30) to be treated, and the device being configured to focus, in use, the light beam (21) at a treatment location inside the skin,whereby Laser Induced Optical Breakdown is induced at the treatment location. The invention also provides a corresponding method to treat skin (30), in particular to reduce wrinkles. The use of the radially-polarizing optical element (radial polarizer) allows a reduction in intensity of the pulse energy in the focal area to produce LIOB. This means that the same level of skin treatment may be obtained with less risk of collateral damage to the tissue surrounding the treatment area
    • 本发明提供了一种用于使用激光治疗皮肤(30)的非侵入性装置,该装置包括:具有用于产生光束(21)的激光源(20)的光学系统(10),开口(13) )允许光束(21)离开设备;以及光学部件(12),被配置为使离开设备的光束(21)径向偏振; 光学系统(10)被配置为使得在使用中,出射光束(21)撞击待处理的皮肤(30)的外表面,并且该装置被配置为在使用中聚焦光束 (21)处于皮肤内的处理位置,由此在处理位置处诱导激光诱导的光学破坏。 本发明还提供了治疗皮肤(30)的相应方法,特别是减少皱纹。 使用径向偏振光学元件(径向偏振器)允许降低焦点区域中的脉冲能量的强度以产生LIOB。 这意味着可以获得相同水平的皮肤治疗,同时对治疗区域周围组织的附带损伤的风险较小