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1. 发明申请

WO2009076482A1 RETRIEVAL APPARATUS AND METHODS FOR USE 审中-公开
标题翻译：检索装置和使用方法
公开(公告)号：WO2009076482A1
公开(公告)日：2009-06-18
申请号：PCT/US2008/086298
申请日：2008-12-10
申请人： INCEPT, LLC , KROLIK, Jeffrey, A.
发明人： KROLIK, Jeffrey, A.
IPC分类号： A61B17/22 , A61F2/01
CPC分类号： A61B17/221 , A61B2017/00862 , A61B2017/22035 , A61B2017/22038 , A61B2017/2212 , A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2230/0069 , A61M1/3655
摘要： An apparatus (10) for capturing material within body lumen includes a shaft (20) carrying an extandable basket device (40) on a distal end thereof. The basket device includes a distal basket (42a) carried and a proximal basket (42b) carried on the shaft such that the proximal basket is proximal to and spaced apart from the distal basket. Each basket includes an open end (46) communicating with an interior of the respective basket and oriented towards one another. In one embodiment, a tubular middle portion (50) extends between the baskets. In another embodiment, the distal basket includes an actuator (124) coupled to the distal basket open end such that movement of the baskets towards one another causes the actuator to direct the distal basket open end inwardly to allow the open end to be received within the proximal basket to facilitate removal of the apparatus after capturing material within the baskets.
摘要翻译：用于捕获体腔内的材料的装置（10）包括：轴（20），其在其远端上承载可延伸的篮装置（40）。筐装置包括承载的远端筐（42a）和承载在所述轴上的近端筐（42b），使得所述近端筐靠近所述远侧筐并与所述远侧筐隔开。每个篮子包括与相应篮子的内部相通并且朝向彼此定向的开放端（46）。在一个实施例中，管状中间部分（50）在篮子之间延伸。在另一个实施例中，远侧筐包括联接到远侧筐开口端的致动器（124），使得篮子朝向彼此的移动导致致动器向内引导远侧筐开放端，以允许开放端被接纳在近端篮子，以便于在筐内捕获材料之后移除装置。

2. 发明申请

WO2010017537A2 APPARATUS AND METHODS FOR ACCESSING AND REMOVING MATERIAL FROM BODY LUMENS 审中-公开
标题翻译：用于从人体透明物质进入和取出材料的装置和方法
公开(公告)号：WO2010017537A2
公开(公告)日：2010-02-11
申请号：PCT/US2009/053237
申请日：2009-08-08
申请人： INCEPT, LLC , KROLIK, Jeffrey, A. , DREHER, James, H. , WATANABE, Gwendolyn
发明人： KROLIK, Jeffrey, A. , DREHER, James, H. , WATANABE, Gwendolyn
IPC分类号： A61B17/22 , A61M25/10
CPC分类号： A61B17/320725 , A61B17/22 , A61B2017/22001 , A61B2017/22054 , A61B2017/22061 , A61B2017/22067 , A61B2017/22068 , A61B2017/22069 , A61B2017/22072 , A61B2017/22079 , A61B2017/2215 , A61M25/04 , A61M25/09 , A61M25/1002 , A61M25/104
摘要： Apparatus are provided for accessing and/or removing material from a body lumen. The apparatus includes a tubular sheath including a shaft having a proximal end and an expandable distal end that is expandable between a collapsed configuration and an expanded, tapered configuration. In one embodiment, the expandable member include inner and outer membranes attached together and to the shaft. Optionally, the inner membrane may include a reinforcement layer and/or the outer membrane may have a longer chord length than the inner membrane, to enhance the expandable member expanding such that a distal opening is defined by the expandable member having s a relatively large diameter tapering proximally to a lumen of the shaft. Optionally, the apparatus may include a dilator and/or one or more treatment devices receivable in the lumen of the shaft.
摘要翻译：提供了用于访问和/或从体腔去除材料的装置。该设备包括管状护套，该管状护套包括具有近端和可扩张远端的轴，该扩张远端可在收缩构造和扩张的渐缩构造之间扩张。在一个实施例中，可膨胀构件包括附接在一起并附接到轴的内膜和外膜。可选地，内膜可以包括增强层和/或外膜可以具有比内膜更长的弦长，以增强可膨胀构件膨胀，使得远端开口由具有相对较大直径渐缩的可膨胀构件限定靠近轴的内腔。任选地，该装置可以包括可容纳在轴腔内的扩张器和/或一个或多个治疗装置。

3. 发明申请

WO2010034021A2 FLOW RESTORATION SYSTEMS AND METHODS FOR USE 审中-公开
标题翻译：流动修复系统和使用方法
公开(公告)号：WO2010034021A2
公开(公告)日：2010-03-25
申请号：PCT/US2009/057918
申请日：2009-09-22
申请人： HOTSPUR TECHNOLOGIES, INC. , KROLIK, Jeffrey, A. , DOMINGO, Juan , MIRZAEE, Daryush , DREHER, James, H.
发明人： KROLIK, Jeffrey, A. , DOMINGO, Juan , MIRZAEE, Daryush , DREHER, James, H.
IPC分类号： A61B17/22 , A61B17/50
CPC分类号： A61B17/3207 , A61B17/221 , A61B17/320725 , A61B2017/00867 , A61B2017/22067 , A61B2017/22069 , A61B2017/22079 , A61B2017/2215 , A61B2017/320741
摘要： Apparatus and methods are provided for removing obstructive material within a body lumen. The apparatus includes a macerator device deployable from a sheath that includes an expandable cage carried by a shaft and within a constraint tube. The shaft is movable relative to the constraint tube for deploying and expanding the cage within a body lumen such that an open end of the cage is oriented towards obstructive material. The cage is advanced to capture the material or the material is directed into the cage using an expandable member expanded beyond the material and retracted to direct the material into the cage. The cage is withdrawn into the constraint tube to compress the cage radially inwardly. Material extending through apertures in the cage are sheared off by a sharpened edge of the constraint tube. The smaller, sheared off particles are then aspirated from the body lumen through the sheath.
摘要翻译：提供了用于去除体腔内的阻塞性物质的装置和方法。该设备包括可从护套展开的剥离器装置，该护套包括由轴承载并且在约束管内的可膨胀笼。该轴相对于约束管是可移动的，用于在体腔内展开和展开笼，使得笼的开放端朝向阻塞性材料。推进笼子以捕获材料，或者使用膨胀超过材料的可膨胀构件将材料引导到笼子中，并且缩回以将材料引导到笼子中。将笼子收回到约束管中以径向向内压缩笼子。延伸通过笼中的孔的材料被约束管的尖锐边缘剪断。较小的剪切掉的颗粒然后通过鞘从体腔吸出。

4. 发明申请

WO2010003135A2 APPARATUS AND METHODS FOR TREATING OBSTRUCTIONS WITHIN BODY LUMENS 审中-公开
标题翻译：用于在体内治疗梗阻的装置和方法
公开(公告)号：WO2010003135A2
公开(公告)日：2010-01-07
申请号：PCT/US2009/049639
申请日：2009-07-02
申请人： HOTSPUR TECHNOLOGIES, INC. , KROLIK, Jeffrey, A. , MIRZAE, Daryush , WATANABE, Gwendolyn , DOMINGO, Juan , DREHER, James, H.
发明人： KROLIK, Jeffrey, A. , MIRZAE, Daryush , WATANABE, Gwendolyn , DOMINGO, Juan , DREHER, James, H.
IPC分类号： A61M31/00 , A61M25/10
CPC分类号： A61M25/104 , A61B17/22032 , A61B17/221 , A61B17/32056 , A61B17/320725 , A61B2017/22034 , A61B2017/22061 , A61B2017/2212 , A61B2017/2215 , A61M25/0075 , A61M25/0097 , A61M25/10 , A61M25/1011 , A61M2025/0008 , A61M2025/1068 , A61M2025/1077 , A61M2025/1084 , A61M2025/1086 , A61M2025/109
摘要： An apparatus is provided that is operable in different modes to perform various functions for treating a body lumen. The apparatus includes a shaft including a proximal end, a distal end, a lumen extending therebetween, and a balloon on the distal end having an interior communicating with the lumen. The apparatus includes a valve on the distal end that selectively opens or closes an outlet communicating with the lumen. With the valve open, fluid introduced into the lumen exits the outlet into a body lumen. With the valve closed, fluid introduced into the lumen expands the balloon. The apparatus also includes an actuator for axially compressing the balloon, and a helical member extends between ends of the balloon interior that expands the balloon from a contracted condition to an expanded helical shape when the actuator is activated.
摘要翻译：提供一种能够以不同模式操作以执行用于治疗体腔的各种功能的装置。所述装置包括轴，所述轴包括近端，远端，在其间延伸的内腔，以及远端上的气囊，其具有与内腔连通的内部。该装置包括在远端上的选择性地打开或关闭与内腔连通的出口的阀。当阀打开时，引入管腔的流体将出口排出到体腔中。随着阀关闭，引入内腔的流体膨胀气囊。该装置还包括用于轴向压缩气囊的致动器，并且螺旋构件在气囊内部的端部之间延伸，当致动器被致动时，气囊从收缩状态膨胀成扩张的螺旋形状。

5. 发明申请

WO2010002549A2 APPARATUS AND METHODS FOR REMOVING OBSTRUCTIVE MATERIAL FROM BODY LUMENS 审中-公开
标题翻译：用于从体内去除阻塞材料的装置和方法
公开(公告)号：WO2010002549A2
公开(公告)日：2010-01-07
申请号：PCT/US2009/046659
申请日：2009-06-08
申请人： HOTSPUR TECHNOLOGIES, INC , KROLIK, Jeffrey, A. , MIRZAE, Daryush , DREHER, James, H. , DOMINGO, Juan , WATANABE, Gwendolyn
发明人： KROLIK, Jeffrey, A. , MIRZAE, Daryush , DREHER, James, H. , DOMINGO, Juan , WATANABE, Gwendolyn
IPC分类号： A61B17/50 , A61B17/22 , A61M1/00
CPC分类号： A61B17/50 , A61B17/221 , A61B17/32075 , A61B2017/00349 , A61B2017/22067 , A61B2017/22079 , A61B2017/2212
摘要： An apparatus is provided for removing material within a body lumen that includes a catheter including a proximal end, a distal end for introduction into a body lumen, and an aspiration lumen extending therebetween; a guide member extending from the distal end and terminating in a distal tip, the guide member comprising a track adjacent a track lumen extending from the distal tip into the aspiration lumen; and an obstruction clearing device deployable from the guide member and retractable along the track. In addition or alternatively, the apparatus includes a cutting head reciprocable within the aspiration lumen adjacent the distal end for macerating material being aspirated into the aspiration lumen.
摘要翻译：提供了一种用于去除体腔内的材料的装置，其包括导管，其包括近端，用于引入体腔的远端和在其间延伸的抽吸腔; 引导构件，其从所述远端延伸并且终止于远侧末端，所述引导构件包括邻近从所述远端延伸到所述抽吸腔内的轨道腔的轨道; 以及阻挡物清除装置，其可从引导构件展开并沿着轨道缩回。另外或替代地，所述设备包括切割头，所述切割头可在靠近所述远端的所述抽吸腔内往复运动，用于浸没材料被吸入所述抽吸腔。

6. 发明申请

WO2012112949A2 APPARATUS AND METHODS FOR TREATING OBSTRUCTIONS WITHIN BODY LUMENS 审中-公开
标题翻译：用于在体内治疗梗阻的装置和方法
公开(公告)号：WO2012112949A2
公开(公告)日：2012-08-23
申请号：PCT/US2012/025734
申请日：2012-02-17
申请人： HOTSPUR TECHNOLOGIES, INC. , KROLIK, Jeffrey, A. , DOMINGO, Juan , WATANABE, Gwendolyn , BETELIA, Ray , FERNANDEZ, Lucas
发明人： KROLIK, Jeffrey, A. , DOMINGO, Juan , WATANABE, Gwendolyn , BETELIA, Ray , FERNANDEZ, Lucas
IPC分类号： A61F2/958
CPC分类号： A61B17/22032 , A61B5/6853 , A61B17/221 , A61B17/32056 , A61B17/3207 , A61B17/320725 , A61B2017/22034 , A61B2017/22061 , A61B2017/22082 , A61B2017/22084 , A61B2017/2212 , A61B2017/2215 , A61F2/958 , A61M5/007 , A61M25/0075 , A61M25/0097 , A61M25/10 , A61M25/1002 , A61M25/1011 , A61M25/10185 , A61M29/02 , A61M2025/0008 , A61M2025/105 , A61M2025/1068 , A61M2025/1077 , A61M2025/1084 , A61M2025/1086 , A61M2025/109
摘要： Apparatus and methods are provided for delivering fluid into a body lumen during a medical procedure. A distal end of an apparatus may be introduced into a body lumen, and a valve on the distal end may be opened to deliver fluid through a first lumen into the body lumen, e.g., contrast and/or other diagnostic or therapeutic agents. The valve may be closed, and a procedure may be performed within the body lumen, e.g., using a treatment element carried on the distal end. For example, the treatment element may include a balloon that may be inflated when fluid is delivered through the first lumen with the valve closed. Optionally, a prosthesis, energy source, drug platform, and the like may be carried by the balloon for treating the body lumen. In various embodiments, the valve may be located proximal or distal to the treatment element.
摘要翻译：提供了设备和方法，用于在医疗过程中将流体输送到体腔中。装置的远端可以被引入体腔，并且可以打开远端上的阀，以将流体通过第一腔输送到体腔，例如造影剂和/或其它诊断或治疗剂。可以关闭阀，并且可以在体腔内执行程序，例如使用在远端上承载的治疗元件。例如，治疗元件可以包括当阀关闭时流体通过第一内腔输送时可膨胀的球囊。任选地，假体，能量源，药物平台等可以由球囊承载以用于处理体腔。在各种实施例中，阀可以位于治疗元件的近侧或远侧。

7. 发明申请

WO2011011765A2 APPARATUS AND METHODS FOR TREATING OBSTRUCTIONS WITHIN BODY LUMENS 审中-公开
标题翻译：用于治疗身体内部障碍的装置和方法
公开(公告)号：WO2011011765A2
公开(公告)日：2011-01-27
申请号：PCT/US2010/043165
申请日：2010-07-23
申请人： HOTSPUR TECHNOLOGIES, INC. , KROLIK, Jeffrey, A. , WATANABE, Gwendolyn , DOMINGO, Juan , BETELIA, Ray , DREHER, James, H. , MIRZAE, Daryush , FERNANDEZ, Lucas
发明人： KROLIK, Jeffrey, A. , WATANABE, Gwendolyn , DOMINGO, Juan , BETELIA, Ray , DREHER, James, H. , MIRZAE, Daryush , FERNANDEZ, Lucas
IPC分类号： A61M25/10 , A61M31/00 , A61M39/22
CPC分类号： A61M25/104 , A61F2/958 , A61M25/0075 , A61M2025/0681 , A61M2025/105 , A61M2025/1063 , A61M2025/1084 , A61M2025/1093
摘要： An apparatus is provided that is operable in different modes to perform various functions for treating a body lumen. The apparatus includes a shaft including proximal and distal ends, a lumen extending therebetween, and a balloon on the distal end. The apparatus includes a valve on the distal end that selectively opens or closes an outlet communicating with the lumen. With the valve open, fluid introduced into the lumen exits the outlet into a body lumen. With the valve closed, fluid introduced into the lumen expands the balloon. The valve may be biased to be closed, e.g., by a spring element disposed within the balloon. Optionally, the apparatus also includes an actuator for expanding a helical member within the balloon interior, e.g., either before or after expanding the balloon, such that the helical member and balloon may adopt an expanded helical shape for removing material within a body lumen.
摘要翻译：提供了一种可在不同模式下操作以执行用于治疗体腔的各种功能的装置。该设备包括轴，该轴包括近端和远端，在其间延伸的内腔以及远端上的气囊。该设备包括在远端上的阀，其选择性地打开或关闭与腔连通的出口。在阀打开的情况下，引入腔中的流体从出口排出到体腔中。在关闭阀的情况下，引入腔中的流体使气囊膨胀。例如，通过设置在球囊内的弹簧元件可以使阀门偏置成关闭。可选地，该装置还包括用于例如在扩张球囊之前或之后扩张球囊内部的螺旋构件的致动器，使得螺旋构件和球囊可以采用扩张的螺旋形状来移除体腔内的物质。 / p>

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