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1. 发明申请

WO2008081480A1 ION ACCELERATION SYSTEM FOR MEDICAL AND/OR OTHER APPLICATIONS 审中-公开
标题翻译：用于医疗和/或其他应用的离子加速系统
公开(公告)号：WO2008081480A1
公开(公告)日：2008-07-10
申请号：PCT/IT2006/000879
申请日：2006-12-28
申请人： FONDAZIONE PER ADROTERAPIA ONCOLOGICA - TERA , AMALDI, Ugo , BRACCINI, Saverio , MAGRIN, Giulio , PEARCE, Peter , ZENNARO, Riccardo
发明人： AMALDI, Ugo , BRACCINI, Saverio , MAGRIN, Giulio , PEARCE, Peter , ZENNARO, Riccardo
IPC分类号： H05H7/22 , H05H9/00 , A61N5/01
CPC分类号： H05H9/00 , A61N5/10 , A61N5/1081 , A61N2005/1087 , G21K5/04 , G21K5/10 , H05H7/22
摘要： The ion acceleration system or complex (T) for medical and/or other applications is composed in essence by an ion source (1), a pre-accelerator (3) and one or more linear accelerators or linacs (6, 8, 10, 13), at least one of which is mounted on a rotating mechanical gantry-like structure (17). Said isocentrical gantry (17) is equipped with a beam delivery system, which can be either 'active' or 'passive', for medical and/or other applications. The ion source (1) and the pre-accelerator (3) can be either installed on the floor, which is connected with the gantry basement, or mounted, fully or partially, on the rotating mechanical structure (17). The output beam can vary in energy and intensity pulse-by-pulse by adjusting the radio-frequency field in the accelerating modules of the linac(s) and the beam parameters at the input of the linear accelerators.
摘要翻译：用于医疗和/或其他应用的离子加速系统或复合物（T）本质上由离子源（1），预加速器（3）和一个或多个线性加速器或直线加速器（6,8,10， 13），其中至少一个安装在旋转的机械机架式结构（17）上。所述异体龙门架（17）配备有可用于医疗和/或其他应用的“活动”或“被动”的射束输送系统。离子源（1）和预加速器（3）可以安装在与龙门架基座连接的地板上，或者完全或部分地安装在旋转的机械结构（17）上。输出光束可以通过调整线性加速器的加速模块中的射频场和线性加速器的输入端的波束参数逐脉冲地变化。

2. 发明申请

WO2006081847A1 ION ACCELERATION SYSTEM FOR HADRONTHERAPY 审中-公开
标题翻译：离子加速系统
公开(公告)号：WO2006081847A1
公开(公告)日：2006-08-10
申请号：PCT/EP2005/011566
申请日：2005-10-28
申请人： FONDAZIONE PER ADROTERAPIA ONCOLOGICA - TERA
发明人： AMALDI, Ugo , CRESCENTI, Massimo , ZENNARO, Riccardo
IPC分类号： H05H9/04 , H05H13/00
CPC分类号： H05H13/00 , G21K5/04 , H05H9/04
摘要： System for ion acceleration for medical purposes comprising a conventional or superconducting cyclotron, a radiofrequency linear accelerator (Linac), a Medium Energy Beam Transport line (MEBT) connected, at the low energy side, to the exit of the cyclotron, and at the other side, to the entrance of the linear radiofrequency accelerator, as well as a High Energy Beam Transport line (HEBT) connected at high energy side to the radiofrequency linear accelerator exit and at the other end, to a system for the dose distribution to the patient. The high frequency of operation of the Linac allows for a reduced consumption and a remarkable compactness facilitating its installation in hospital structures. The use of a modular LINAC allows varying in active way the energy and the current of the therapeutic beam, having a small emittance and a time structure adapted to the dose distribution based on the technique known as the "spot scanning".
摘要翻译：用于医疗用途的用于离子加速的系统包括常规或超导回旋加速器，在低能量侧连接到回旋加速器的出口的射频线性加速器（Linac），中等能量束输送线（MEBT）以及另一个侧向线性射频加速器的入口以及在高能量侧连接到射频线性加速器出口的另一端的高能束输送线（HEBT）连接到用于剂量分配给患者的系统。线性面包线的高频率运行允许减少消耗和显着的紧凑性，便于其在医院结构中的安装。使用模块化的LINAC允许主动地改变基于被称为“点扫描”的技术的具有适合于剂量分布的小的发射率和时间结构的治疗束的能量和电流。

3. 发明申请

WO2004054331A1 LINAC FOR ION BEAM ACCELERATION 审中-公开
标题翻译： LINAC用于离子束加速
公开(公告)号：WO2004054331A1
公开(公告)日：2004-06-24
申请号：PCT/EP2003/006254
申请日：2003-06-13
申请人： FONDAZIONE PER ADROTERAPIA ONCOLOGICA - TERA
发明人： AMALDI, Ugo , CRESCENTI, Massimo , ZENNARO, Riccardo
IPC分类号： H05H9/04
CPC分类号： H05H9/00 , H05H7/22
摘要： A drift tube (15) linear accelerator (linac) (4) that can be used for the acceleration of low energy ion beams is disclosed. The particles enter the linac (4) at low energy and are accelerated and focused along a straight line in a plurality of resonant accelerating structures (8) interposed by coupling structures (9) up to the desired energy, for instance for therapeutic needs. In the accelerating structures (8), excited by an H-type resonant electromagnetic field, a plurality of accelerating gaps (20) is provided between said drift tubes (15), said drift tubes being supported by stems, for instance alternatively horizontally (16) and vertically (17) disposed. A basic module (7) is disclosed, composed of two accelerating structures (8) and an interposed coupling structure (9), or if necessary a modified coupling structure (9A) connected to a RF power generator (11), being linked if necessary to a vacuum system (13 ) and equipped if necessary with one or more quadrupoles (18). Said basic module (7) can be expanded to get modules (7A) that present an odd number n of coupling structures (9, 9A) which still if necessary are equipped with one or more quadrupoles (18), and an even number N = n + 1 of accelerating structures (8). The proposed linac (4) contains one or more modules (7, 7A) and allows obtaining a large accelerating gradient and a very compact structure.
摘要翻译：公开了一种可用于加速低能量离子束的漂移管（15）直线加速器（直线加速器）（4）。颗粒以低能量进入直线加速器（4），并且在多个谐振加速结构（8）中沿着直线加速聚焦，所述多个谐振加速结构（8）插入通过耦合结构（9）达到期望的能量，例如用于治疗需要。在由H型共振电磁场激发的加速结构（8）中，在所述漂移管（15）之间设置有多个加速间隙（20），所述漂移管由杆支撑，例如水平地（16 ）和垂直（17）。公开了由两个加速结构（8）和插入的耦合结构（9）组成的基本模块（7），或者如果需要，连接到RF发电机（11）的修改的耦合结构（9A），如果需要则链接到真空系统（13）并且如果必要的话配备一个或多个四极杆（18）。所述基本模块（7）可以被扩展以获得呈现奇数N个耦合结构（9,9A）的模块（7A），其仍然需要配备有一个或多个四极（18），偶数N = n + 1加速结构（8）。所提出的直线加速器（4）包含一个或多个模块（7,7A），并且允许获得大的加速梯度和非常紧凑的结构。

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