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1. 发明申请

WO2016154180A1 ABRASION RESISTANT FILM FOR BIOCONTAINERS 审中-公开
标题翻译：生物测定仪的耐磨膜
公开(公告)号：WO2016154180A1
公开(公告)日：2016-09-29
申请号：PCT/US2016/023534
申请日：2016-03-22
申请人： EMD MILLIPORE CORPORATION
发明人： DECOSTE, David , CIANCIOLO, Joseph , FURBUSH, Michael , SARAGOSA, John
IPC分类号： B32B27/12 , B32B5/02 , B32B27/08 , B32B27/32 , B32B27/34 , B32B27/40 , B65D33/04
CPC分类号： B32B5/024 , B01L3/508 , B01L2300/0887 , B01L2300/16 , B32B5/02 , B32B5/022 , B32B27/08 , B32B27/12 , B32B27/32 , B32B27/34 , B32B27/40 , B32B2262/0253 , B32B2262/0261 , B32B2262/0269 , B32B2262/0276 , B32B2262/103 , B32B2262/106 , B32B2307/554 , B32B2307/7242 , B32B2439/40 , B32B2439/80 , B65D65/40 , B65D75/58 , B65D2275/00 , G01M3/3272
摘要： A biocontainer film enhanced with an abrasion resistant or "cut-proof" substrate. Such substrates can be combined with current biocontainer materials, via various techniques of embedding, coextrusion or laminating, to maintain the cleanliness and low extractables already validated for biotech manufacturing. The substrate of choice may be constructed from materials known to be more resistant to abrasion and sharp razor type cuts or from materials oriented in such a way to prevent puncture to occur. The new substrate must also be flexible to allow for typical folding as demonstrated by current packaging practices. The new substrate may be constructed from materials other than polymers such as metal, glass or carbon or in combination with polymers. A non-constrained pressure test is also disclosed.
摘要翻译：具有耐磨损或“切割”基材增强的生物容器膜。这种基材可以通过各种嵌入，共挤出或层压技术与目前的生物容器材料结合，以保持已经为生物技术制造验证的清洁度和低提取物。所选择的基底可以由已知更耐磨损和锋利的剃刀类型切割的材料构成，或者由以防止穿刺发生的方式定向的材料构成。新的基材也必须是柔性的，以允许通过当前包装实践证明的典型折叠。新基材可以由除了聚合物以外的材料如金属，玻璃或碳或与聚合物组合构成。还公开了非约束压力试验。

2. 发明申请

WO2020101848A1 REINFORCED FILM FOR BIOCONTAINERS 审中-公开
公开(公告)号：WO2020101848A1
公开(公告)日：2020-05-22
申请号：PCT/US2019/057554
申请日：2019-10-23
申请人： EMD MILLIPORE CORPORATION
发明人： PEREIRA, Brian , SARAGOSA, John , MULDOON, Joseph
IPC分类号： B32B27/12 , B32B3/26 , B32B5/02 , B32B7/12 , B32B27/08 , B32B27/30 , B32B27/32 , B32B27/34 , B32B27/36
摘要： A material for biocontainers comprising a film formed of two or more layers forming a body to the film, the film having an interior and exterior side, and a substrate incorporated in the body of the film wherein the substrate is formed of a fibrous material, wherein each of the at least one of the two or more layers comprises an ethylene vinyl acetate resin. A non-constrained pressure test is also disclosed.

3. 发明申请

WO2021050484A1 ARTICULATING BIOCONTAINERS 审中-公开
公开(公告)号：WO2021050484A1
公开(公告)日：2021-03-18
申请号：PCT/US2020/049846
申请日：2020-09-09
申请人： EMD MILLIPORE CORPORATION
发明人： CLEVELAND, Shannon , VARLAMOVA, Marina , SARAGOSA, John , DECOSTE, David , CACACE, Benjamin , LAMOTHE, Daniel , GAGNE, George , DEE, James
IPC分类号： C12M1/00 , C12M23/14 , C12M23/26 , C12M41/44
摘要： A biocontainer having a first film, the film having an interior and exterior side; articulating elements disposed on or within the first film, the articulating elements comprising at least one a folded hinge, a sealed joint, a thinned pathway, a bowed path, an embedded polymeric or metallic cylindrical fiber or rod; and a second film, optionally comprising articulating elements, joined to the first film, to form a biocontainer having a closed volume, wherein the articulating elements permit the biocontainer to expand and collapse along the articulating elements.

4. 发明申请

WO2014099811A1 INTERFACE AND FLUID-TRANSFER SYSTEM 审中-公开
标题翻译：接口和流体传输系统
公开(公告)号：WO2014099811A1
公开(公告)日：2014-06-26
申请号：PCT/US2013/075460
申请日：2013-12-16
申请人： EMD MILLIPORE CORPORATION
发明人： SARAGOSA, John , CIECIUCH, John , KELLY, James E. , MESSIER, Luc , VIGORITO, Nicholas
IPC分类号： G01N1/10 , G01N1/22
CPC分类号： F16K3/04 , G01N1/10 , G01N1/22 , G01N1/2226 , G01N2001/1037
摘要： A fluid transfer system (100) includes a transfer device (104) and an interface device (102). The transfer device (104) includes a fluid transfer member (164) and a transfer coupling member (125) to align the fluid transfer member (164) with the interface device (102). The interface device (102) includes a reservoir port (108), a fluid transfer member receptacle (144), an interface coupling member (124), and a reservoir valve (110). The interface coupling member (124) is configured to close the fluid transfer member receptacle (144) and to couple to the transfer coupling member (125) and open the fluid transfer member receptacle (144) to receive the fluid transfer member (164). The reservoir valve (110), e.g., a sliding seal, is configured to close the reservoir port (108) from the fluid transfer member receptacle (144) and to open the reservoir port (108) to the fluid transfer member (164) when the fluid transfer member (164) is positioned in the fluid transfer member receptacle (144). The fluid transfer member (164) can include a plunger assembly configured to open and close the reservoir port (108).
摘要翻译：流体传输系统（100）包括传送装置（104）和接口装置（102）。传送装置（104）包括流体传送构件（164）和传送联接构件（125），以使流体传送构件（164）与界面装置（102）对准。接口装置（102）包括储存器端口（108），流体转移构件容器（144），界面连接构件（124）和储存器阀（110）。接口联接构件（124）构造成关闭流体转移构件容器（144）并且联接到传递联接构件（125）并打开流体转移构件容器（144）以接收流体传递构件（164）。储存器阀（110）（例如滑动密封件）构造成从流体转移构件接收器（144）关闭储存器端口（108）并且将储存器端口（108）打开到流体转移构件（164）时，当流体传递构件（164）定位在流体转移构件容器（144）中。流体转移构件（164）可以包括构造成打开和关闭储存器端口（108）的柱塞组件。

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