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    • 1. 发明申请
    • METHOD AND FORMULATION FOR NEUTRALIZING TOXIC CHEMICALS AND MATERIALS
    • 中毒化学品和材料中和方法与制剂
    • WO2009094098A2
    • 2009-07-30
    • PCT/US2008/088547
    • 2008-12-30
    • E-Z-EM, INC.HENRY, Timothy, G.PRICE, Barbara, B.
    • HENRY, Timothy, G.PRICE, Barbara, B.
    • A62D3/30A62D3/33
    • A62D3/36A61K8/40A61Q17/00A62D3/30A62D3/33A62D2101/02A62D2101/04A62D2101/22A62D2101/24A62D2101/26A62D2101/28A62D2101/43A62D2101/45A62D2101/47A62D2101/49
    • The present invention is directed to a formulation and associated method for neutralizing one or more toxic chemical and/or materials including toxic industrial chemicals and toxic industrial materials, such as irritants, heavy metals, radioactive metals, acids and acid irritants, pesticides, and various agricultural chemicals, (collectively referred to as toxic chemical, materials, or simply toxins) as well as decontaminating surfaces that have come into contact with these agents. As a result, the formulation of the present invention can be used for neutralizing a broad spectrum of toxic chemicals and materials. In one embodiment, the active ingredient comprises 2, 3, butanedione monoxime (also known as diacetyl monoxime (DAM)), and alkali salts thereof such as potassium 2,3-butanedione monoxime (KBDO). The formulation also typically includes a carrier in which the active ingredient is dispersed. In one embodiment, the carrier comprises polyethylene glycol (PEG); monomethoxypolyethylene glycol(mPEG); and combinations and derivatives thereof.
    • 本发明涉及一种用于中和一种或多种有毒化学物质和/或材料的制剂和相关方法,所述有毒化学物质和/或材料包括毒性工业化学品和毒性工业材料,例如刺激物,重金属,放射性金属,酸和酸性刺激物,农药和各种 农药(统称为有毒化学品,材料或简单毒素)以及与这些药剂接触的表面去污。 结果,本发明的配方可用于中和广谱的有毒化学物质和材料。 在一个实施方案中,活性成分包含2,3-丁二酮单肟(也称为二乙酰单肟(DAM))及其碱金属盐,例如2,3-丁二酮一肟钾(KBDO)。 制剂通常还包括其中分散有活性成分的载体。 在一个实施方案中,载体包含聚乙二醇(PEG); 单甲氧基聚乙二醇(mPEG); 及其组合和衍生物。