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1. 发明申请

WO2014188403A1 GUIDEWIRE HAVING SELECTIVELY ADJUSTABLE STIFFNESS AND TIP CURVATURE 审中-公开
标题翻译：具有可选择的可调节刚度和尖端曲线的GUIDEWIRE
公开(公告)号：WO2014188403A1
公开(公告)日：2014-11-27
申请号：PCT/IL2014/050386
申请日：2014-04-29
申请人： CARDIOSERT LTD.
发明人： SHEKALIM, Avraham , PELEG, Noam
IPC分类号： A61M25/09 , A61M25/01
CPC分类号： A61M25/09 , A61M25/09025 , A61M2025/09116 , A61M2025/0915 , A61M2025/09175
摘要： A guidewire assembly (10) having selectively adjustable stiffness and tip curvature includes a hollow guidewire (12) having a distal portion (14) terminating at a distal tip (16), a curvature-modifying element (18) anchored to the distal tip, and a stiffness-modifying element (20) displaceable within the hollow guidewire towards and away form the distal tip so as to vary a stiffness of the distal element are frictionally linked such that movement of the stiffness-modifying element from a current position over a first range of motion causes corresponding displacement of the curvature-modifying element, thereby modifying a state of curvature of a least part of the distal portion of the guidewire. Movement of the stiffness-modifying element beyond the first range of motion displaces the stiffness-modifying element relative to the curvature-modifying element.
摘要翻译：具有选择性可调节的刚度和尖端曲率的导丝组件（10）包括具有终止于远侧末端（16）的远端部分（14）的空心导丝（12），锚固到远侧末端的曲率修正元件（18）并且刚性改变元件（20）可以在所述中空导丝内朝向和远离形成所述远侧末端移位，以便改变所述远侧元件的刚度被摩擦地连接，使得刚度修正元件从当前位置移动到第一运动范围引起曲率修正元件的相应位移，从而改变导丝的远端部分的至少部分的曲率状态。刚度修正元件超过第一运动范围的运动使刚度修改元件相对于曲率修正元件移位。

2. 发明申请

WO2013118105A1 GUIDE WIRE FOR USE WITH CARDIOVASCULAR LESIONS 审中-公开
标题翻译：指导用于心脏病的指南
公开(公告)号：WO2013118105A1
公开(公告)日：2013-08-15
申请号：PCT/IB2013/051144
申请日：2013-02-12
申请人： CARDIOSERT LTD.
发明人： SHEKALIM, Avraham , PELEG, Noam
IPC分类号： A61M25/00
CPC分类号： A61B17/22 , A61B2017/22094 , A61M25/09 , A61M25/09025 , A61M2025/09083 , A61M2025/0915 , A61M2025/09183 , A61M2210/125
摘要： A guide wire includes elements in a telescoping arrangement which impart stiffness to the guide wire for maneuverability in the tortious cardiac vessels. This arrangement also creates engagements between an inner shaft and the tip, that when released, result in a tip which can move outward with forces sufficient to penetrate a lesion in the coronary vessels.
摘要翻译：引导线包括伸缩装置中的元件，其向导丝施加刚度，以在侵入性心脏血管中的机动性。这种布置还产生内轴和尖端之间的接合，当被释放时，导致可以用足以穿透冠状血管中的损伤的力向外移动的尖端。

3. 发明申请

WO2018104941A1 GUIDEWIRE SYSTEM FOR INTRA-VASCULAR PRESSURE MEASUREMENT 审中-公开
公开(公告)号：WO2018104941A1
公开(公告)日：2018-06-14
申请号：PCT/IL2017/051320
申请日：2017-12-05
申请人： CARDIOSERT LTD.
发明人： SHEKALIM, Avraham , PELEG, Noam
IPC分类号： A61B17/00 , A61M25/00 , A61B5/00
摘要： A pressure-measuring guidewire system includes a hollow guidewire (110) in sealed interconnection with a contained volume (102) of a connector (101). The contained volume is bordered on at least one side by a septum (103). A pressure sensor unit (122) includes a transducer (130) associated with a hollow needle (131) which can be inserted to penetrate the septum (103), thereby connecting the transducer with a column of fluid within an inner lumen of the guidewire (102). Priming of the guidewire is performed prior to use, typically by use of a syringe, prior to connection of the sensor unit, thereby protecting the transducer from damage from the priming pressure. Also disclosed is a guidewire tip configuration which provides effective fluid connection for pressure measurement while maintaining the properties of a conventional guidewire.

4. 发明申请

WO2017033182A1 DOUBLE CONCENTRIC GUIDEWIRE 审中-公开
标题翻译：双重集中指导
公开(公告)号：WO2017033182A1
公开(公告)日：2017-03-02
申请号：PCT/IL2016/050907
申请日：2016-08-18
申请人： CARDIOSERT LTD.
发明人： SHEKALIM, Avraham , PELEG, Noam
IPC分类号： A61M25/09
CPC分类号： A61M25/09041 , A61M2025/09083 , A61M2025/09116 , A61M2025/0915
摘要： A double guide wire includes two guidewires (100, 300) deployed concentrically, one within the other, Each guidewire is formed as an elongated flexible shaft (1 10, 120, 310. 320) having a distal portion including a deflectable helical coil (111, 314) terminating at a distal tip (11 5, 311). The first guidewire (100) is implemented as a hollow guidewire having a central lumen (150) extending along: its length, while the second guidewire (300) is configured as a smaller gauge guidewire deployed within the central lumen of the first guidewire. Art adjuster mechanism (210) allows the inner guidewire to be advanced and retracted relative to the outer guidewire, transforming the guidewire between! a first state in which the distal, tip of the second guidewire is adjacent to the distal tip of the first guidewire; and a second state in which at least part of the distal portion of the inner guidewire is advanced beyond distal tip of the first guidewire.
摘要翻译：双引导线包括两个同心设置的导线（100,300），一个在另一个之内。每个导丝形成为具有远端部分的细长柔性轴（110,102,310,320），远端部分包括可偏转螺旋线圈，314）终止于远侧末端（11,5,311）。第一导丝（100）被实施为具有沿着其长度延伸的中心腔（150）的中空导丝，而第二导丝（300）被配置为布置在第一导丝的中心腔内的较小规格导丝。艺术调整机构（210）允许内部导丝相对于外部导丝推进和缩回，第一状态，其中第二导丝的远端尖端与第一导丝的远端相邻; 以及第二状态，其中内导丝的远端部分的至少一部分超过第一导丝的远端。

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