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1. 发明申请

WO2008013928A2 TREATMENT OF CANCER WITH INTERFERON GENE DELIVERY IN COMBINATION WITH A TGF-BETA INHIBITOR 审中-公开
标题翻译：用与TGF-β抑制剂组合的干扰素基因递送的癌症治疗
公开(公告)号：WO2008013928A2
公开(公告)日：2008-01-31
申请号：PCT/US2007/016880
申请日：2007-07-27
申请人： BIOGEN IDEC MA INC. , THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA , PARR, Michael , LING, Leona , ALBELDA, Steven , KIM, Samuel
发明人： PARR, Michael , LING, Leona , ALBELDA, Steven , KIM, Samuel
IPC分类号： A61K48/00
CPC分类号： A61K48/005 , A61K31/7088 , A61K45/06 , A61K2300/00
摘要： The invention provides methods for cancer treatment, comprising administering to a subject in need of the treatment a combination therapy which comprises (a) administration of a TGF-β inhibitor and (b) a vector comprising an isolated polynucleotide which encodes an interferon polypeptide.
摘要翻译：本发明提供了用于癌症治疗的方法，包括向需要治疗的受试者施用组合疗法，其包括（a）施用TGF-β抑制剂和（b）包含编码干扰素多肽的分离的多核苷酸的载体。

2. 发明申请

WO2020222902A1 PLANAR LUNEBURG LENS SYSTEM FOR TWO-DIMENSIONAL OPTICAL BEAM STEERING 审中-公开
公开(公告)号：WO2020222902A1
公开(公告)日：2020-11-05
申请号：PCT/US2020/020393
申请日：2020-02-28
申请人： MASSACHUSETTS INSTITUTE OF TECHNOLOGY , LOPEZ, Josue , KIM, Samuel , SLOAN, Jamison , KHARAS, Boris , HERD, Jeffrey Scott , SOLJACIC, Marin , SORACE-AGASKAR, Cheryl Marie , BRAMHAVAR, Suraj Deepak , JOHNSON, Steven Glenn , BARBASTATHIS, George
发明人： LOPEZ, Josue , KIM, Samuel , SLOAN, Jamison , KHARAS, Boris , HERD, Jeffrey Scott , SOLJACIC, Marin , SORACE-AGASKAR, Cheryl Marie , BRAMHAVAR, Suraj Deepak , JOHNSON, Steven Glenn , BARBASTATHIS, George
IPC分类号： G01S7/481 , G02B6/122 , G02B6/124 , G01S17/42 , G01S17/931 , G01S7/4817 , G01S7/4818 , G02B2006/12102 , G02B2006/12107 , G02B6/12004 , G02B6/125 , G02F1/2955
摘要： An integrated optical beam steering device includes a planar Luneburg lens that collimates beams from different inputs in different directions within the lens plane. It also includes a curved (e.g., semi-circular or arced) grating coupler that diffracts the collimated beams out of the lens plane. The beams can be steered in the plane by controlling the direction along which the lens is illuminated and out of the plane by varying the beam wavelength. Unlike other beam steering devices, this device can operate over an extremely wide field of view — up to 180° — without any aberrations off boresight. In other words, the beam quality is uniform in all directions, unlike with aplanatic lenses, thanks to the circular symmetry of the planar Luneburg lens, which may be composed of sub wavelength features. The lens is also robust to misalignment and fabrication imperfections and can be made using standard CMOS processes.

3. 发明申请

WO2008086090A1 SELF-ASSEMBLED HETEROGENEOUS INTEGRATED OPTICAL ANALYSIS SYSTEM 审中-公开
标题翻译：自组装异构一体化光学分析系统
公开(公告)号：WO2008086090A1
公开(公告)日：2008-07-17
申请号：PCT/US2008/050104
申请日：2008-01-03
申请人： UNIVERSITY OF WASHINGTON , KIM, Samuel , AMIRPARVIZ, Babak , MELDRUM, Deirdre , SAEEDI, Ehsan
发明人： KIM, Samuel , AMIRPARVIZ, Babak , MELDRUM, Deirdre , SAEEDI, Ehsan
IPC分类号： H01L27/14 , H01L31/0232 , G01N21/27
CPC分类号： H01L25/167 , B01L3/5027 , G01N21/253 , G01N21/6454 , H01L24/95 , H01L25/042 , H01L31/18 , H01L2924/09701 , H01L2924/12041 , H01L2924/12043 , H01L2924/00
摘要： Optical analysis system fluidically self-assembled using shape-coded freestanding optoelectronic components and a template having shape-coded recessed binding sites connected by an embedded interconnect network. Also includes methods of manufacture and use for optical analyses.
摘要翻译：光学分析系统使用形状编码的独立光电子元件进行流体自组装，以及具有通过嵌入式互连网络连接的形状编码的嵌入式结合位点的模板。还包括制造和使用光学分析的方法。

4. 发明申请

WO2005055514A1 METHODS, SYSTEMS AND COMPUTER PROGRAM PRODUCTS FOR AUTOMATIC REKEYING IN AN AUTHENTICATION ENVIRONMENT 审中-公开
标题翻译：认证环境中自动认证的方法，系统和计算机程序产品
公开(公告)号：WO2005055514A1
公开(公告)日：2005-06-16
申请号：PCT/US2004/039372
申请日：2004-11-22
申请人： NETIQ CORPORATION , YEH, Ryhwei , HAILI, Ma , KIM, Samuel
发明人： YEH, Ryhwei , HAILI, Ma , KIM, Samuel
IPC分类号： H04L9/08
CPC分类号： H04L63/0823 , H04L9/0891 , H04L9/3247 , H04L9/3265 , H04L9/3271 , H04L41/28 , H04L63/062
摘要： Rekeying in an authentication system including an authenticated data processing system (10) and an authenticating data processing system (20) is provided by the authenticating data processing system detecting failure of an authentication of the authenticated data processing system with a current public key associated with the authenticated data processing system and automatically updating the current public key associated with the authenticated data processing system with an updated public key responsive to detecting failure of an authentication of the authenticated data processing system with the current public key. Automatic rekeying of a client in a server-side authentication system is provided. Automatic rekeying may occur upon detection by the client that server authentication has failed. The automatic rekeying may include requesting an updated key from a server. The request may include an identification of the current public key of the client and the server may access a repository of previous keys to sign the updated public key sent to the client with a private key corresponding to the current public key of the client.
摘要翻译：通过认证数据处理系统，通过认证数据处理系统（10）和认证数据处理系统（20）的认证系统中的密钥来检测认证数据处理系统的认证失败，并使用与响应于利用当前公共密钥检测认证数据处理系统的认证失败，使用更新的公开密钥自动更新与认证数据处理系统相关联的当前公钥。提供了服务器端认证系统中客户端的自动重新密钥密钥。当客户端检测到服务器认证失败时，可能会发生自动重新密钥密钥。自动重新键入可以包括从服务器请求更新的密钥。该请求可以包括客户端的当前公共密钥的标识，并且服务器可以访问先前密钥的存储库，以使用与客户端的当前公钥相对应的私钥对发送给客户端的更新的公钥进行签名。

5. 发明申请

WO2011140085A1 MECHANICAL SINTERING OF NANOPARTICLE INKS AND POWDERS 审中-公开
标题翻译：纳米油墨和粉末的机械烧结
公开(公告)号：WO2011140085A1
公开(公告)日：2011-11-10
申请号：PCT/US2011/034995
申请日：2011-05-03
申请人： APPLIED NANOTECH HOLDINGS, INC. , LI, Yunjun , KIM, Samuel , PAVLOVSKY, Igor , YANIV, Zvi , YANG, Mohshi
发明人： LI, Yunjun , KIM, Samuel , PAVLOVSKY, Igor , YANIV, Zvi , YANG, Mohshi
IPC分类号： H01B5/00 , C09D5/00 , H01R43/00
CPC分类号： C23C24/08
摘要： Nanoparticle inks and powders are sintered using an applied mechanical energy, such as uniaxial pressure, hydrostatic pressure, and ultrasonic energy, which may also include applying a sheer force to the inks or powders in order to make the resultant film or line conductive.
摘要翻译：使用所应用的机械能，例如单轴压力，静水压力和超声能量来烧结纳米颗粒油墨和粉末，其还可以包括对油墨或粉末施加明显的力，以使得到的膜或管线导电。

6. 发明申请

WO2009062055A1 FREE-STANDING TWO-SIDED DEVICE FABRICATION 审中-公开
标题翻译：自由站立双面设备制造
公开(公告)号：WO2009062055A1
公开(公告)日：2009-05-14
申请号：PCT/US2008/082827
申请日：2008-11-07
申请人： UNIVERSITY OF WASHINGTON , KIM, Samuel , AMIRPARVIZ, Babak
发明人： KIM, Samuel , AMIRPARVIZ, Babak
IPC分类号： G01R31/26
CPC分类号： H01L31/022416 , H01L27/14 , H01L31/02165 , H01L31/103 , H01L31/1035 , H01L31/1804 , H01L31/1812 , H01L31/184 , H01L31/1852 , Y02E10/544 , Y02E10/547 , Y02P70/521
摘要： Devices having features deposited on two sides of a device substrate and methods for making the same. The devices are useful, for example, as the components in a macroelectronic system. In a preferred embodiment, the devices are photosensors having a plurality of electrodes patterned on a first side of the device and an electromagnetic interference filter patterned on a second side of the device. The method facilitates the fabrication of two-sided devices through the use of an immobilizing layer deposited on top of devices patterned on a first side of a device substrate; flipping the device substrate; processing the second side of the device substrate to produce patterned features on the second side of the device substrate; and releasing the devices having patterned elements on two sides of each device.
摘要翻译：具有沉积在器件基板两侧的特征的器件及其制造方法。这些装置例如作为宏电子系统中的组件是有用的。在优选实施例中，装置是具有在装置的第一侧上图案化的多个电极的光电传感器和在装置的第二侧上图案化的电磁干涉滤光器。该方法通过使用沉积在器件衬底的第一侧上图案化的器件的顶部上的固定层来促进制造双面器件; 翻转装置基板; 处理器件衬底的第二面以在器件衬底的第二侧上产生图案化特征; 并且在每个装置的两侧释放具有图案化元件的装置。

7. 发明申请

WO2012154712A1 BURNTHROUGH FORMULATIONS 审中-公开
标题翻译：烧伤配方
公开(公告)号：WO2012154712A1
公开(公告)日：2012-11-15
申请号：PCT/US2012/036880
申请日：2012-05-08
申请人： APPLIED NANOTECH HOLDINGS, INC. , ABED, Ovadia , LI, Yunjun , NOVAK, James P. , KIM, Samuel , FERGUSON, Patrick
发明人： ABED, Ovadia , LI, Yunjun , NOVAK, James P. , KIM, Samuel , FERGUSON, Patrick
IPC分类号： C09K13/00
CPC分类号： H01B1/02 , H01L31/022425 , Y02E10/50 , Y10S977/773
摘要： For solar cell fabrication, the addition of precursors to printable media to assist etching through silicon nitride or silicon oxide layer thus affording contact with the substance underneath the nitride or oxide layer. The etching mechanism may be by molten ceramics formed in situ, fluoride-based etching, as well as a combination of the two.
摘要翻译：对于太阳能电池制造，向可印刷介质添加前体以辅助蚀刻通过氮化硅或氧化硅层，从而提供与氮化物或氧化物层下面的物质的接触。蚀刻机构可以是通过原位形成的熔融陶瓷，基于氟化物的蚀刻，以及两者的组合。

8. 发明申请

WO2011149931A1 THERMAL MANAGEMENT COMPOSITE MATERIALS 审中-公开
标题翻译：热管理复合材料
公开(公告)号：WO2011149931A1
公开(公告)日：2011-12-01
申请号：PCT/US2011/037731
申请日：2011-05-24
申请人： APPLIED NANOTECH HOLDINGS, INC. , JIANG, Nan , KIM, Samuel , YANIV, Zvi
发明人： JIANG, Nan , KIM, Samuel , YANIV, Zvi
IPC分类号： F28F7/00 , H05K7/20
CPC分类号： C22C32/0084 , B22F2998/00 , B82Y30/00 , C22C26/00 , C22C47/14 , C22C2026/002 , H01L2924/0002 , C22C1/05 , B22F1/025 , B22F3/14 , B22F2303/01 , B22F2301/052 , B22F2303/05 , B22F2302/40 , B22F2302/403 , B22F7/04 , H01L2924/00
摘要： Graphite aluminum composites for use in thermal management applications, such as heat sinks, are manufactured using pressure molds. The materials may be mixed previous to insertion into the mold, or can be mixed within the mold. Further, graphitic particles, such as graphitic needle coke surfaces, can be coated with the aluminum before the mold process is performed. Further, ceramic sheets can be inserted into the mixture before the mold process is performed so that the molded material can then be sliced to provide a carbon aluminum composite plate with a ceramic sheet on one of its surfaces.
摘要翻译：用于热管理应用（如散热器）的石墨铝复合材料使用压力模具制造。这些材料可以在插入模具之前混合，或者可以在模具内混合。此外，在进行模具加工之前，可以用铝涂覆石墨颗粒，例如石墨针状焦炭表面。此外，在进行模具加工之前，可以将陶瓷片材插入到混合物中，从而可以将模制材料切片，以在其表面之一上提供具有陶瓷片的碳铝复合板。

9. 发明申请

WO2010065739A1 ENHANCING THERMAL PROPERTIES OF CARBON ALUMINUM COMPOSITES 审中-公开
标题翻译：增加碳铝复合材料的热性能
公开(公告)号：WO2010065739A1
公开(公告)日：2010-06-10
申请号：PCT/US2009/066582
申请日：2009-12-03
申请人： APPLIED NANOTECH, INC. , YANIV, Zvi , PAVLOVSKY, Igor , JIANG, Nan , NOVAK, James, P. , FINK, Richard , YANG, Mohshi , MAO, Dongsheng , KIM, Samuel
发明人： YANIV, Zvi , PAVLOVSKY, Igor , JIANG, Nan , NOVAK, James, P. , FINK, Richard , YANG, Mohshi , MAO, Dongsheng , KIM, Samuel
IPC分类号： C25D7/04
CPC分类号： B32B5/18 , C04B35/522 , C04B35/528 , C04B35/645 , C04B41/009 , C04B41/5155 , C04B41/88 , C04B2111/00844 , C04B2235/3817 , C04B2235/3826 , C04B2235/402 , C04B2235/428 , C04B2235/6021 , C04B2235/616 , C04B2235/80 , C04B2235/9607 , C09K5/14 , C22C1/08 , C22C1/1036 , C22C32/0084 , C22C2001/081 , H01L23/373 , H01L23/3736 , H01L2924/0002 , H01L2924/3011 , Y10T428/12042 , Y10T428/249994 , C04B41/4521 , C04B41/4523 , C04B41/5096 , H01L2924/00
摘要： An article of manufacture comprises a carbon-containing matrix. The carbon- containing matrix may comprise at least one type of carbon material selected from the group comprising graphite crystalline carbon materials, carbon powder, and artificial graphite powder. In addition, the carbon-containing matrix comprises a plurality of pores. The article of manufacture also comprises a metal component comprising Al, alloys of Al, or combinations thereof. The metal component is disposed in at least a portion of the plurality of pores. Further, the article of manufacture comprises an additive comprising at least Si. At least a portion of the additive is disposed in an interface between the metal component within the pores and the carbon-containing matrix. The additive enhances phonon coupling and propagation at the interface.
摘要翻译：制品包括含碳基质。含碳基质可以包括选自包括石墨结晶碳材料，碳粉末和人造石墨粉末的组的至少一种类型的碳材料。此外，含碳基质包含多个孔。该制品还包括包含Al，Al的合金或其组合的金属组分。金属部件设置在多个孔的至少一部分中。此外，制品包含至少包含Si的添加剂。至少一部分添加剂被设置在孔内的金属组分和含碳基质之间的界面中。该添加剂增强了界面处的声子耦合和传播。

10. 发明申请

WO2008033540A2 MOTION SICKNESS REDUCTION 审中-公开
标题翻译：运动病减轻
公开(公告)号：WO2008033540A2
公开(公告)日：2008-03-20
申请号：PCT/US2007/020068
申请日：2007-09-13
申请人： KIM, Samuel
发明人： KIM, Samuel
IPC分类号： G01N33/574
CPC分类号： G06T3/40 , A61M21/02 , A61M2021/005 , G06F3/011
摘要： A motion sickness reduction device includes an image capture device for capturing an image of a device environment and an image display device for displaying an image related to the captured image. In order to effectively prevent or reduce motion sickness, the right amount of motion must be displayed on the image display device when the vehicle accelerates or turns. Various methods are disclosed for adjusting the image on the display device and/or the angle of the environment subtended to make the motion sickness reduction device effective.
摘要翻译：晕动病减轻装置包括用于捕捉设备环境的图像的图像捕捉设备和用于显示与捕捉的图像有关的图像的图像显示设备。为了有效地防止或减少晕车，当车辆加速或转弯时，必须在图像显示装置上显示正确的运动量。公开了用于调节显示装置上的图像和/或对准环境的角度以使晕动病减轻装置有效的各种方法。

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