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1. 发明申请

WO2006036926B1 EFFICIENT SYNTHESIS OF 4,5-DIHYDRO-PYRAZOLO[3,4-C]PYRID-2-ONES 审中-公开
标题翻译：高效合成4,5-二氢吡唑并[3,4-C]吡啶-2-酮
公开(公告)号：WO2006036926B1
公开(公告)日：2007-03-15
申请号：PCT/US2005034511
申请日：2005-09-27
申请人： SQUIBB BRISTOL MYERS CO , MUDRYK BOGUSLAW M , CUNIERE NICOLAS , HSIEH DAU-MING , ROSSANO LUCIUS , LIANG JING , CHEN BANG-CHI , ZHANG HUIPING , ZHAO RULIN , WANG BEI , DAVID ADRIAN
发明人： MUDRYK BOGUSLAW M , CUNIERE NICOLAS , HSIEH DAU-MING , ROSSANO LUCIUS , LIANG JING , CHEN BANG-CHI , ZHANG HUIPING , ZHAO RULIN , WANG BEI , DAVID ADRIAN
IPC分类号： C07D471/04 , A61K31/437 , A61P7/02
CPC分类号： C07D471/04
摘要： A novel process and intermediates thereof for making 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones of the type shown below from appropriate phenyl hydrazines is described. Formula (I). These compounds can be useful as factor Xa inhibitors.
摘要翻译：描述了从合适的苯基肼制备下文所示类型的4,5-二氢 - 吡唑并[3,4-c]吡啶-2-酮的新方法和中间体。公式（I）。这些化合物可用作Xa因子抑制剂。

2. 发明申请

WO2006036949A2 PREPARATION OF N-ARYL PYRIDONES 审中-公开
标题翻译： N-芳基吡啶酮的制备
公开(公告)号：WO2006036949A2
公开(公告)日：2006-04-06
申请号：PCT/US2005/034553
申请日：2005-09-27
申请人： BRISTOL-MYERS SQUIBB COMPANY , ZHANG, Huiping , CHEN, Bang-Chi , ZHAO, Rulin
发明人： ZHANG, Huiping , CHEN, Bang-Chi , ZHAO, Rulin
IPC分类号： C07D213/70
CPC分类号： C07D213/64
摘要： A novel process and intermediates thereof for making N-aryl pyridones of the type shown below from appropriate pyridinolates is described. These compounds are useful as intermediates for the synthesis of clinical candidates.
摘要翻译：描述了用于从合适的吡啶醇合物制备下文所示类型的N-芳基吡啶酮的新方法和其中间体。这些化合物可用作合成临床候选药物的中间体。

3. 发明申请

WO2005066274A1 POLYCARBONATE POLYESTER MOLDING COMPOSITION 审中-公开
标题翻译：聚碳酸酯聚酯模塑组合物
公开(公告)号：WO2005066274A1
公开(公告)日：2005-07-21
申请号：PCT/US2004/038063
申请日：2004-11-15
申请人： GENERAL ELECTRIC COMPANY , ZHANG, Huiping , VOLLENBERG, Peter, H., Th.
发明人： ZHANG, Huiping , VOLLENBERG, Peter, H., Th.
IPC分类号： C08L69/00
CPC分类号： C08L69/00 , C08L25/14 , C08L67/02 , C08L2666/18 , C08L2666/02
摘要： A clear thermoplastic blend comprises from about 25 to about 90 percent by weight of low flow polycarbonate resin having a MVR (Melt Viscosity Rate) of from about 1 to about 7 cc/10 min at 300°C/1.2kg and from about 10 to about 75 percent by weight of a polyester resin derived from the condensation of a cyclohexanedimethanol or equivalent thereof alone or with an ethylene glycol or equivalent thereof with a terephthalic acid or equivalents thereof or a combination of terephthalic acid and isophthalic acid or equivalents thereof.
摘要翻译：透明的热塑性共混物包含约25至约90重量％的低流量聚碳酸酯树脂，其在300℃/ 1.2kg下具有约1至约7cc / 10min的MVR（熔体粘度），约10至约75重量％的衍生自环己烷二甲醇或其等同物单独或与乙二醇或其等同物与对苯二甲酸或其等同物或者对苯二甲酸和间苯二甲酸或其等同物的组合缩合的聚酯树脂。

4. 发明申请

WO2009083829A3 METHODS AND APPARATUS FOR EVENT DISTRIBUTION IN MESSAGING SYSTEMS 审中-公开
公开(公告)号：WO2009083829A3
公开(公告)日：2009-07-09
申请号：PCT/IB2008/055052
申请日：2008-12-02
申请人： TELEFONAKTIEBOLAGET L M ERICSSON (PUBL) , ZHU, Zhongwen , ZHANG, Huiping
发明人： ZHU, Zhongwen , ZHANG, Huiping
IPC分类号： G06F9/50
摘要： Methods and apparatus for distributing events among a set of traffic processors in a telecommunication network. The methods and apparatus determines a traffic processor from the set of traffic processors with the lowest traffic load, the traffic load is determined for each traffic processor of the set of traffic processors based on a weighting factor, an event queue length of a traffic processors and a current traffic load. Events are re-distributed when a change occurs in the set of traffic processors. The re-distribution is based on a determination of an allowable event queue length for each traffic processor of the set of traffic processors, which is based on the current traffic load, an optimal traffic load and a maximum event queue length.

5. 发明申请

WO2007084478A3 MISCIBLE POLYCARBONATE POLYESTER BLENDS 审中-公开
标题翻译：混溶性聚碳酸酯聚酯共混物
公开(公告)号：WO2007084478A3
公开(公告)日：2007-09-13
申请号：PCT/US2007001075
申请日：2007-01-16
申请人： GEN ELECTRIC , SHAIKH ABBAS ALLI G , PAL SUBODH KUMAR , RAVI GOMATAM RAGHAVAN , RAMARAJU DEEPAK , RAJESWARAN RAMESH , KANNAN GANESH , SHI XIAODONG , ZHANG HUIPING , CHAMBERS CHARLES
发明人： SHAIKH ABBAS ALLI G , PAL SUBODH KUMAR , RAVI GOMATAM RAGHAVAN , RAMARAJU DEEPAK , RAJESWARAN RAMESH , KANNAN GANESH , SHI XIAODONG , ZHANG HUIPING , CHAMBERS CHARLES
IPC分类号： C08L67/02 , C08L69/00
CPC分类号： C08L67/02 , C08L69/00 , C08L2666/18
摘要： A thermoplastic resin composition is disclosed which includes: structural units derived at least one substituted or unsubstituted polycarbonate, and a polyester comprising structural units derived from at least greater than 40 mole percent of xylene glycol, such that the composition is miscible. Also disclosed is a process of making said thermoplastic compositions and articles derived from said composition. The composition disclosed possess good optical properties, thermal properties and stability.
摘要翻译：公开了一种热塑性树脂组合物，其包含衍生自至少一种取代或未取代的聚碳酸酯的结构单元和包含衍生自至少大于40摩尔％二甲苯二醇的结构单元的聚酯，使得该组合物是可混溶的。还公开了制造所述热塑性组合物和由所述组合物衍生的制品的方法。所公开的组合物具有良好的光学性能，热性能和稳定性。

6. 发明申请

WO2006135425A3 PREPARATION OF 4,5-DIHYDRO-PYRAZOLO[3,4-C]PYRID-2-ONES 审中-公开
标题翻译： 4,5-二羟基 - 吡唑并[3,4-C]吡啶-2-酮的制备
公开(公告)号：WO2006135425A3
公开(公告)日：2007-02-22
申请号：PCT/US2005034551
申请日：2005-09-27
申请人： SQUIBB BRISTOL MYERS CO , ZHAO RULIN , CHEN BANG-CHI , WANG BEI , ZHANG HUIPING
发明人： ZHAO RULIN , CHEN BANG-CHI , WANG BEI , ZHANG HUIPING
IPC分类号： C07D471/16
CPC分类号： C07D487/04 , C07D471/04
摘要： A novel process and intermediates thereof for making 4,5-dihydro-pyrazolo[3,4 c]pyrid-2-ones of the type shown below, as well as the corresponding pyrazoles, from appropriate phenyl hydrazines is described. O (R2b) 0-2 R1 I I 1 1-a X 2 N N-, R a' IV These compounds can be useful as factor Xa inhibitors.
摘要翻译：描述了用于制备下列所示类型的4,5-二氢 - 吡唑并[3,4-C]吡啶-2-酮的新方法及其中间体，以及相应的吡唑。 O（R2b）0-2 R1 II 1 1-a X 2 N N - ， - - - SIPO - >这些化合物可用作因子Xa抑制剂。

7. 发明申请

WO2006135425A2 PREPARATION OF 4,5-DIHYDRO-PYRAZOLO[3,4-C]PYRID-2-ONES 审中-公开
标题翻译： 4,5-二羟基 - 吡唑并[3,4-C]吡啶-2-酮的制备
公开(公告)号：WO2006135425A2
公开(公告)日：2006-12-21
申请号：PCT/US2005/034551
申请日：2005-09-27
申请人： BRISTOL-MYERS SQUIBB COMPANY , ZHAO, Rulin , CHEN, Bang-Chi , WANG, Bei , ZHANG, Huiping
发明人： ZHAO, Rulin , CHEN, Bang-Chi , WANG, Bei , ZHANG, Huiping
CPC分类号： C07D487/04 , C07D471/04
摘要： A novel process and intermediates thereof for making 4,5-dihydro-pyrazolo[3,4 c]pyrid-2-ones of the type shown below, as well as the corresponding pyrazoles, from appropriate phenyl hydrazines is described. O (R2b) 0-2 R1 I I 1 1-a X 2 N N-, R a' IV These compounds can be useful as factor Xa inhibitors.
摘要翻译：描述了用于制备下列所示类型的4,5-二氢 - 吡唑并[3,4-C]吡啶-2-酮的新方法及其中间体，以及相应的吡唑。 O（R2b）0-2 R1 II 1 1-a X 2 N N - ， - - - SIPO - >这些化合物可用作因子Xa抑制剂。

8. 发明申请

WO2004105694A3 PHARMACEUTICAL COMPOSITIONS AND DOSAGE FORMS FOR ADMINISTRATION OF HYDROPHOBIC DRUGS 审中-公开
公开(公告)号：WO2004105694A3
公开(公告)日：2004-12-09
申请号：PCT/US2004/016286
申请日：2004-05-24
申请人： LIPOCINE, INC. , CHEN, Feng-Jing , PATEL, Mahesh, V. , FIKSTAD, David, T. , ZHANG, Huiping , GILIYAR, Chandrashekar
发明人： CHEN, Feng-Jing , PATEL, Mahesh, V. , FIKSTAD, David, T. , ZHANG, Huiping , GILIYAR, Chandrashekar
IPC分类号： A61K31/355 , A61K31/56 , C07J53/00
摘要： Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs, particularly steroids, are provided. The pharmaceutical compositions include a therapeutically effective amount of a hydrophobic drug, preferably a steroid; a solubilizer, preferably a vitamin E substance; and a surfactant. The synergistic effect between the hydrophobic drug and the vitamin E substance results in a pharmaceutical formulation with improved dispersion of both the active agent and the solubilizer. As a result of the improved dispersion, the pharmaceutical composition has improved bioavailability upon administration. Methods of improving the bioavailability of hydrophobic drugs administered to a patient are also provided.

9. 发明申请

WO2014162301A1 OBJECT-ORIENTED OPEN FRAMEWORK FOR THE GENERATION OF INSTALLATION SCRIPT FILES 审中-公开
标题翻译：面向对象的开放框架用于安装脚本文件的生成
公开(公告)号：WO2014162301A1
公开(公告)日：2014-10-09
申请号：PCT/IB2014/060443
申请日：2014-04-04
申请人： TELEFONAKTIEBOLAGET L M ERICSSON (PUBL) , ZHANG, Huiping
发明人： ZHANG, Huiping
IPC分类号： G06F9/445
CPC分类号： G06F8/61 , G06F8/70
摘要： A campaign generation framework is provided for generating a campaign file that describes actions for installing a software bundle on a highly available system. A campaign initialization procedure compliant with the Software Management Framework (SMF) is automatically generated based on a configuration file and an Entity Types File (ETF). The configuration file describes a deployment configuration of the highly available system, and the ETF describes the software bundle. The SMF defines Extensible Markup Language (XML) schemas that include XML elements organized as a hierarchy. A hierarchy of entities types is constructed for the deployment configuration from top to bottom of the hierarchy using the campaign generation framework that includes a set of object-oriented classes and methods provided by the classes. Each XML element in the XML schemas corresponds to one of the classes, and the classes are grouped into module classes according to the hierarchy of the XML elements.
摘要翻译：提供了一个活动生成框架，用于生成一个活动文件，该活动文件描述了在高可用性系统上安装软件包的操作。根据配置文件和实体类型文件（ETF）自动生成符合软件管理框架（SMF）的活动初始化过程。配置文件描述了高可用性系统的部署配置，ETF描述了软件包。 SMF定义了可扩展标记语言（XML）模式，其包含组织为层次结构的XML元素。使用包含一组由类提供的面向对象的类和方法的活动生成框架，为层次结构的顶部到底部的部署配置构建实体类型的层次结构。 XML模式中的每个XML元素都对应于其中一个类，根据XML元素的层次结构将类分成模块类。

10. 发明申请

WO2007001385B1 PROCESS FOR PREPARING 4,5-DIHYDRO-PYRAZOLO [3,4-C] PYRID-2-ONES 审中-公开
标题翻译：制备4,5-二氢吡唑并[3,4-C]吡啶-2-酮的方法
公开(公告)号：WO2007001385B1
公开(公告)日：2007-07-12
申请号：PCT/US2005034548
申请日：2005-09-27
申请人： SQUIBB BRISTOL MYERS CO , SHAPIRO RAFAEL , ROSSANO LUCIUS T , MUDRYK BOGUSLAW M , CUNIERE NICOLAS , OBERHOLZER MATTHEW , ZHANG HUIPING , CHEN BANG-CHI
发明人： SHAPIRO RAFAEL , ROSSANO LUCIUS T , MUDRYK BOGUSLAW M , CUNIERE NICOLAS , OBERHOLZER MATTHEW , ZHANG HUIPING , CHEN BANG-CHI
IPC分类号： C07D471/04
CPC分类号： C07D471/04
摘要： A novel process and intermediates thereof for making 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones of the type shown below from appropriate phenyl hydrazines is described. These compounds can be useful as factor Xa inhibitors.
摘要翻译：描述了从合适的苯基肼制备下文所示类型的4,5-二氢 - 吡唑并[3,4-c]吡啶-2-酮的新方法和中间体。这些化合物可用作Xa因子抑制剂。

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