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1. 发明申请

WO2023076424A2 COMPOSITIONS AND METHODS FOR DISEASE TREATMENT AND PREVENTION BY PH MODIFIERS AND/OR CELL PROLIFERATION INHIBITORS 审中-公开
公开(公告)号：WO2023076424A2
公开(公告)日：2023-05-04
申请号：PCT/US2022/047932
申请日：2022-10-26
申请人： ZENG, Wei-ping
发明人： ZENG, Wei-ping
IPC分类号： A61K45/06 , A61P35/00 , A61P35/04 , A61K31/4706 , A61K31/133 , A61K31/14
摘要： This invention focuses on the cellular differences in response to pH alterations and a key role of the cells' proliferative statuses in determining their responses. Therefore, methods and compositions are designed to use pH modifiers and cell proliferation inhibitors to treat or prevent diseases with pathogenesis attributable to inflammation, immune response, cell proliferation, or combinations thereof. The pH modifiers, particularly but not exclusively those that lower or resist the rise of pH, are used to deplete pathological inflammatory and/or proliferating cells. Conversely, pH modifiers that raise or resist the fall of pH are used to increase the population and the proliferation of normal protective cells.

2. 发明申请

WO2011002397A1 METHOD AND ARRANGEMENT HANDLING PLUGGABLE MODULES AND OPERATING MODES IN A MEDIA CONVERTER SYSTEM 审中-公开
标题翻译：媒体转换系统中的可插拔模块和操作模式的方法和布置
公开(公告)号：WO2011002397A1
公开(公告)日：2011-01-06
申请号：PCT/SE2010/050680
申请日：2010-06-17
申请人： TELEFONAKTIEBOLAGET LM ERICSSON (publ) , HUANG, Wei-Ping
发明人： HUANG, Wei-Ping
IPC分类号： G02B6/42 , H04B10/24 , H04L12/24
CPC分类号： H04L45/28 , H04L12/40169 , H04L12/40182 , H04L69/08
摘要： A method handling a pluggable module selectable from a plurality of pluggable modules is executable at a media converter system of a network configuration. The method provides for automatically enabling of a disabled channel or disabling of an enabled channel of the media converter system when the pluggable module is attached to the media converter system, wherein the suggested channel enabling/disabling feature is executed on the basis of a correlation between module specific information extracted from the respective pluggable module and corresponding information extracted via the media converter system. An arrangement for executing the suggested method is also provided.
摘要翻译：处理可从多个可插拔模块选择的可插拔模块的方法可在网络配置的媒体转换器系统处执行。该方法提供了当可插拔模块附接到媒体转换器系统时，自动启用禁用频道或禁用媒体转换器系统的启用频道，其中建议的频道使能/禁用特征是基于从相应的可插拔模块提取的模块特定信息和经由媒体转换器系统提取的对应信息。还提供了用于执行所提出的方法的装置。

3. 发明申请

WO2009058522A3 A PROCESS FOR REJUVENATING A CATALYST COMPOSITION 审中-公开
标题翻译：一种催化催化剂组合物的方法
公开(公告)号：WO2009058522A3
公开(公告)日：2009-06-25
申请号：PCT/US2008079051
申请日：2008-10-07
申请人： EXXONMOBIL CHEM PATENTS INC , HELTON TERRY E , NANDA VIJAY , TAI WEI-PING , JURGENS-KOWAL TERESA A , KEVILLE KATHLEEN M
发明人： HELTON TERRY E , NANDA VIJAY , TAI WEI-PING , JURGENS-KOWAL TERESA A , KEVILLE KATHLEEN M
IPC分类号： B01J29/04 , B01J29/08 , B01J29/18 , B01J29/70 , B01J29/90 , B01J38/02 , B01J38/04
CPC分类号： B01J38/02 , B01J29/041 , B01J29/08 , B01J29/18 , B01J29/7007 , B01J29/90 , B01J38/04
摘要： This disclosure relates to a method for rejuvenating a catalyst, comprising contacting the catalyst with a gaseous feedstock at rejuvenation conditions for at least one hour to form a rejuvenated catalyst and a gaseous product, wherein the catalyst comprises at least 10 wt.% of a molecular sieve, wherein the catalyst prior to the contacting step comprises from 0.001 wt.% to 45 wt.% of hydrocarbons and 0.001 to 10 wt.% nitrogen containing components based on the total weight of the catalyst prior to the contacting step, wherein the molecular sieve comprises at least one of a MCM-22 family molecular sieve, a molecular sieve having a framework type of *BEA, a molecular sieve having a framework type of FAU, and a molecular sieve having a framework type of MOR, wherein the gaseous feedstock comprises at least one of N2, H2, alkane, He, Ar, CO, and CO2, wherein the gaseous product has at least a portion of the gaseous feedstock and at least a portion of the hydrocarbons of the catalyst and at least a portion of the nitrogen containing components of the catalyst, wherein the rejuvenation conditions comprise a temperature in the range from about 400 to 6000C, a pressure in the range from about 101.3 kPa-a to 10130 kPa-a, a space hourly velocity in the range of from 0.05 to 10 hr-1.
摘要翻译：本公开涉及一种用于使催化剂再生的方法，包括在再生条件下将催化剂与气体原料接触至少1小时以形成复原催化剂和气态产物，其中催化剂包含至少10重量％的分子筛，其中在接触步骤之前的催化剂包含0.001重量％至45重量％的烃和0.001至10重量％的含氮组分，基于在接触步骤之前催化剂的总重量，其中分子筛子包括MCM-22族分子筛，具有骨架类型为* BEA的分子筛，具有骨架类型的FAU的分子筛和具有骨架类型MOR的分子筛中的至少一种，其中气态原料包括N 2，H 2，烷烃，He，Ar，CO和CO 2中的至少一种，其中气态产物具有气态原料的至少一部分和催化剂的至少一部分烃和所述催化剂的含氮组分的至少一部分，其中所述再生条件包括在约400-600℃范围内的温度，在约101.3kPa-a至10130kPa-a的范围内的压力，空间时速在0.05至10小时-1的范围内。

4. 发明申请

WO2007148102A3 CRYSTALLINE DULOXETINE HYDROCHLORIDE 审中-公开
标题翻译：水杨酸丁酯氢氯化物
公开(公告)号：WO2007148102A3
公开(公告)日：2008-03-13
申请号：PCT/GB2007002324
申请日：2007-06-21
申请人： ARROW INT LTD , CHONGQING SHENGHUAXI PHARMA CO , TABATZNIK ANTHONY S , JIANG WEI PING , JIA CHUN RONG
发明人： JIANG WEI PING , JIA CHUN RONG
IPC分类号： C07D333/20 , A61K31/381
CPC分类号： C07D333/20
摘要： Crystalline duloxetine hydrochloride, compositions containing the same and methods for the production thereof.
摘要翻译：结晶度洛西汀盐酸盐，含有其的组合物及其制备方法。

5. 发明申请

WO2007078243A1 CLADDING ALIGNMENT FOR FUSION SPLICING OPTICAL FIBERS 审中-公开
标题翻译：用于熔丝分离光纤的层压对准
公开(公告)号：WO2007078243A1
公开(公告)日：2007-07-12
申请号：PCT/SE2006/001520
申请日：2006-12-29
申请人： TELEFONAKTIEBOLAGET LM ERICSSON (PUBL) , HUANG, Wei-Ping , AHLSTEDT, Kjell
发明人： HUANG, Wei-Ping , AHLSTEDT, Kjell
IPC分类号： G02B6/255
CPC分类号： G02B6/2555 , G02B6/2551
摘要： In aligning ends of optical fibers (13), e.g. for performing a prealignment of ends of large mode area double-clad fibers (LMA-DCFs) in order to thereafter perform a core alignment process, in a fiber optic fusion splicer a best, optimum or near optimum position or setting of the optical system (7) for observing the self-focusing effect is first determined and then the very alignment operation may be performed using the determined setting. The very alignment process may then be performed by adjusting stepwise the offset distance between the observed fiber ends by e.g. using a cascade technique.
摘要翻译：在对准光纤（13）的端部时，例如，为了进行大型区域双包层光纤（LMA-DCF）的端部的预对准，以便在光纤熔接机中进行光纤对准处理，光纤系统的最佳，最佳或接近最佳位置或设置（首先确定用于观察自聚焦效果的图7），然后可以使用所确定的设置执行非常对准操作。然后可以通过如下步骤来逐步调节观察到的光纤端部之间的偏移距离来执行非常对准过程。使用级联技术。

6. 发明申请

WO2004042000A2 157 HUMAN SECRETED PROTEINS 审中-公开
标题翻译： 157人类分泌蛋白
公开(公告)号：WO2004042000A2
公开(公告)日：2004-05-21
申请号：PCT/US2003/015439
申请日：2003-05-16
申请人： HUMAN GENOME SCIENCES, INC. , ROSEN, Craig, A. , RUBEN, Steven, M. , OLSEN, Henrik , BAKER, Kevin, P. , FISCELLA, Michele , WEI, Ping , BIRSE, Charles, E. , KOMATSOULIS, George , CHOI, Gil, H. , MOORE, Paul, A. , GUPTA, Ram , SHI, Yanggu
发明人： ROSEN, Craig, A. , RUBEN, Steven, M. , OLSEN, Henrik , BAKER, Kevin, P. , FISCELLA, Michele , WEI, Ping , BIRSE, Charles, E. , KOMATSOULIS, George , CHOI, Gil, H. , MOORE, Paul, A. , GUPTA, Ram , SHI, Yanggu
IPC分类号： C12N
CPC分类号： C07K14/47 , A61K38/00
摘要： The present invention relates to human secreted polypeptides, and isolated nucleic acid molecules encoding said polypeptides, useful for diagnosing and treating diseases, disorders, and/or conditions related to said human secreted proteins. Antibodies that bind these polypeptides are also encompassed by the present invention. Also encompassed by the invention are vectors, host cells, and recombinant and synthetic methods for producing said polynucleotides, polypeptides, and/or antibodies. The invention further encompasses screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further encompasses methods and compositions for inhibiting or enhancing the production and function of the polypeptides of the present invention.
摘要翻译：本发明涉及人分泌多肽和编码所述多肽的分离的核酸分子，其可用于诊断和治疗与所述人分泌蛋白相关的疾病，病症和/或病症。结合这些多肽的抗体也包括在本发明中。本发明还包括载体，宿主细胞，以及用于产生所述多核苷酸，多肽和/或抗体的重组和合成方法。本发明还包括用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。本发明还包括用于抑制或增强本发明多肽的产生和功能的方法和组合物。

7. 发明申请

WO2003104456A1 IMMUNOMODULATION USING ALTERED DENDRITIC CELLS 审中-公开
标题翻译：使用改变的DENDRITIC细胞进行免疫调节
公开(公告)号：WO2003104456A1
公开(公告)日：2003-12-18
申请号：PCT/CA2003/000867
申请日：2003-06-10
申请人： LONDON HEALTH SCIENCES CENTRE RESEARCH INC. , MIN, Wei-Ping , ICHIM, Thomas , HILL, Jonathan
发明人： MIN, Wei-Ping , ICHIM, Thomas , HILL, Jonathan
IPC分类号： C12N15/11
CPC分类号： C12N15/1136 , A61K35/12 , A61K2039/5158 , C12N5/0639 , C12N5/064 , C12N2310/14 , C12N2310/53 , C12N2510/00
摘要： The invention relates to altered immune cells and their use in methods and compositions to alter the immune system in a mammal. More specifically, the invention is directed to the alteration of gene expression in antigen presenting cells such as dendritic cells (DC) and their use in various methods and compositions to alter T cell activity for the treatment of a variety of immune disorders.
摘要翻译：本发明涉及改变的免疫细胞及其在改变哺乳动物免疫系统的方法和组合物中的用途。更具体地，本发明涉及抗原呈递细胞如树突状细胞（DC）中基因表达的改变及其在各种方法和组合物中用于改变T细胞活性以治疗各种免疫疾病的用途。

8. 发明申请

WO2003096088A1 FUSION TEMPERATURE CALIBRATION 审中-公开
标题翻译：熔融温度校准
公开(公告)号：WO2003096088A1
公开(公告)日：2003-11-20
申请号：PCT/SE2003/000529
申请日：2003-04-02
申请人： TELEFONAKTIEBOLAGET LM ERICSSON (publ) , HUANG, Wei-Ping
发明人： HUANG, Wei-Ping
IPC分类号： G02B6/255
CPC分类号： G02B6/2551 , G01K11/06
摘要： The present invention relates to a method for accurately calibrating fusion temperature in optical fiber splicing. With assistance of direct arc-recentering technique, two optical fibers are spliced and then continuously heated with a post-fusion process. In the process, the fusion temperature is automatically determined in terms of effective fusion currents, which is done by real-time monitoring the fusion time dependence of cladding diameter reduction. In comparison with model calculations, variations of fusion temperature caused by changes of electrode condition and operating environment, e.g. altitude, temperature and humidity are derived. To recover the optimal fusion temperature in various fusion processes, the calibrating results are automatically invoked to compensate fusion currents.
摘要翻译：本发明涉及一种精确校准光纤拼接熔化温度的方法。借助于直接电弧重合技术，将两根光纤拼接，然后用后融合工艺连续加热。在此过程中，融合温度根据有效融合电流自动确定，这通过实时监测包层直径减小的融合时间依赖性来实现。与模型计算相比，由电极条件和操作环境的变化引起的融合温度的变化，例如，导出高度，温度和湿度。为了恢复各种融合过程中的最佳融合温度，自动调用校准结果来补偿融合电流。

9. 发明申请

WO2003017987A1 BIODEGRADABLE POLYMERIC NANOCAPSULES AND USES THEREOF 审中-公开
标题翻译：可生物降解的聚合物纳米粒子及其用途
公开(公告)号：WO2003017987A1
公开(公告)日：2003-03-06
申请号：PCT/CA2002/001331
申请日：2002-08-28
申请人： MCGILL UNIVERSITY , CHANG, Thomas, M., S. , YU, Wei-Ping , POWANDA, Douglas
发明人： CHANG, Thomas, M., S. , YU, Wei-Ping , POWANDA, Douglas
IPC分类号： A61K9/51
CPC分类号： A61K9/5153 , A61K38/42
摘要： The present invention relates to a biodegradable polymeric nanocapsule composition, adaptable for encapsulation of an agent of therapeutic interest for enhancing the in vivo circulation time of thereof and uses thereof.
摘要翻译：本发明涉及一种可生物降解的聚合物纳米胶囊组合物，其适于包封用于增强其体内循环时间的治疗用途的药剂及其用途。

10. 发明申请

WO0061823B1 METHOD AND DEVICE FOR TAPPING MOLTEN METAL FROM METALLURGICAL VESSELS 审中-公开
标题翻译：方法和装置离别冶金熔炼容器焊缝金属熔化的
公开(公告)号：WO0061823B1
公开(公告)日：2001-02-01
申请号：PCT/EP0003064
申请日：2000-04-06
申请人： SCHLOEMANN SIEMAG AG , DEPPNER KARL HEINZ , WU WEI PING
发明人： DEPPNER KARL-HEINZ , WU WEI-PING
IPC分类号： B22D41/06 , B22D43/00 , C21C5/46 , C21C5/52 , C21C7/00 , F27B3/19 , F27B3/22 , F27B3/28 , F27D3/14 , F27D3/15 , F27D3/16 , F27D11/08
CPC分类号： C21C5/4693
摘要： In order to impede entrainment or trailing of molten slag (1) while tapping molten metal (2) from a metallurgical vessel (5) having a tap hole (1) in the bottom (13) of said vessel, the molten slag (1) is blown away from the surface of the molten metal in the area of the tap hole (10) (2) by a gas jet (9) with high impulsive energy.
摘要翻译：为与容器底部（13）自来水开口（10）一个冶金容器（5）的金属熔液（2）的出钢时布置成防止与熔渣的轴或狩猎旋转（1），它是按照本发明所提出，（通过气体射流 9）具有高脉冲能量，熔融炉渣（1）（在出渣口10的区域）（熔融金属2）吹塑的表面。

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