专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2021058986A1 ATOMIC LAYER DEPOSITION METHOD OF METAL (II), (0), OR (IV) CONTAINING FILM LAYER 审中-公开
公开(公告)号：WO2021058986A1
公开(公告)日：2021-04-01
申请号：PCT/GB2020/052345
申请日：2020-09-28
申请人： THE UNIVERSITY OF BATH
发明人： PARISH, James. D , JOHNSON, Andrew. L
IPC分类号： C23C16/455 , C23C16/40 , C23C16/30 , C07F7/22 , C07F7/24
摘要： The present invention relates to the use of a M (II) primary precursor of formula (I) wherein: M is Sn or Ge or Pb; L is a ligand displaying ALD reactivity for a secondary precursor; R1, R2, and R3 are each independently selected from: H or a linear or branched alkyl groups, and wherein at least one of R1, R2 and R3 is a linear or branched alkyl group, or an adduct of a metal (M) (II) precursor of formula (I), in the atomic layer deposition (ALD) of a M (II), M (0), or a M (IV) containing film layer on a substrate.

2. 发明申请

WO2020128015A2 SCREENING ASSAY 审中-公开
公开(公告)号：WO2020128015A2
公开(公告)日：2020-06-25
申请号：PCT/EP2019/086750
申请日：2019-12-20
申请人： THE UNIVERSITY OF BATH
发明人： MASON, Jody Michael , KAD, Neil Mark
IPC分类号： G01N33/50 , C12Q1/6897
摘要： Disclosed are methods, kits and cells for screening for test compounds that are capable of inhibiting DNA-binding activity of a DNA-binding protein. The disclosed methods, kits and cells may include a reporter expression cassette that encodes a reporter expression product, wherein the reporter expression cassette comprises at least one binding site for the DNA-binding protein such that binding of the DNA- binding protein to the binding site inhibits expression of the reporter expression product. Also disclosed are methods for producing a helix-constrained peptide that may be used in the screening methods disclosed herein. The methods, kits and cells find application, for example, in the identification of antagonists that may be useful in the treatment of cancers involving the DNA-binding protein.

3. 发明申请

WO2020099853A1 AN ALKALI METAL VAPOR ENCLOSURE 审中-公开
公开(公告)号：WO2020099853A1
公开(公告)日：2020-05-22
申请号：PCT/GB2019/053197
申请日：2019-11-12
申请人： UNIVERSITY OF BATH
发明人： VALEV, Ventsislav , MOSLEY, Peter , WADSWORTH, William , SLAVOV, Dimitar , RUSIMOVA, Kristina
IPC分类号： G04F5/14
摘要： An alkali metal vapor enclosure comprising: an internal surface comprising nanostructures; a transmissive portion to enable the internal surface to be illuminated; wherein the enclosure contains atoms of an alkali metal which are in a vapor state and/or adsorbed onto the internal surface; and wherein illumination of the internal surface via the transmissive portion with light having a frequency to cause a temperature rise in the nanostructures by exciting an enhanced optical extinction mechanism in the nanostructures, causes an increase in the density of the alkali metal vapor.

4. 发明申请

WO2016177994A1 COMPOSITE ELASTIC WAVE WAVEGUIDE 审中-公开
标题翻译：复合弹性波浪波
公开(公告)号：WO2016177994A1
公开(公告)日：2016-11-10
申请号：PCT/GB2016/051124
申请日：2016-04-22
申请人： UNIVERSITY OF BATH
发明人： CHEREDNICHENKO, Kirill , COOPER, Shane
IPC分类号： G10K11/162 , G10K11/168 , E02D27/34 , E04H9/02 , G10K11/24 , G10K11/36
CPC分类号： G10K11/162 , E02D27/34 , G10K11/168 , G10K11/24 , G10K11/36
摘要： Aspects and embodiments provide a method of selecting physical characteristics of elements forming a composite elastic waveguide structure configurable to propagate an elastic wave and a composite elastic waveguide structure formed from elements having selected physical characteristics. The method comprises: selecting an elastic wave propagation speed within the composite structure; calculating, based on the selected elastic wave propagation speed, a range of values for at least one the physical characteristic of at least one of at least two elements forming the composite structure, such that propagation of the elastic wave through the combined elements of the composite material at the selected elastic wave propagation speed occurs according to a wave mode in which displacement of a surface of the composite material formed from the at least two elements is substantially zero. Aspects recognise that the propagation of elastic waves in a composite material waveguide may differ from the propagation of elastic waves in a homogeneous material waveguide. In particular, in an appropriately designed composite material, an elastic wave of may propagate through the composite structure and leave, for example, the upper surface of the composite structure substantially unmoved. Homogeneous structures do not allow for propagation of elastic waves in such a manner.
摘要翻译：方面和实施例提供了一种选择形成复合弹性波导结构的元件的物理特性的方法，所述复合弹性波导结构可配置成传播弹性波，以及由具有选定物理特性的元件形成的复合弹性波导结构。该方法包括：在复合结构内选择弹性波传播速度; 基于所选择的弹性波传播速度计算形成复合结构的至少两个元件中的至少一个的至少一个的物理特性的值的范围，使得弹性波通过复合材料的组合元件的传播根据由至少两个元件形成的复合材料的表面的位移基本上为零的波模式发生选择的弹性波传播速度下的材料。方面认识到复合材料波导中弹性波的传播可能与均质材料波导中的弹性波的传播不同。特别地，在适当设计的复合材料中，弹性波可以传播通过复合结构，并且离开例如复合结构的上表面基本上不被移动。均匀结构不允许以这种方式传播弹性波。

5. 发明申请

WO2016097751A1 METHOD OF CAS9 MEDIATED GENOME ENGINEERING 审中-公开
标题翻译： CAS9介导的基因工程方法
公开(公告)号：WO2016097751A1
公开(公告)日：2016-06-23
申请号：PCT/GB2015/054066
申请日：2015-12-18
申请人： THE UNIVERSITY OF BATH
发明人： PERRY, Anthony , SUZUKI, Toru , ASAMI, Maki
IPC分类号： A01K67/027 , C12N15/90 , C12N15/85 , C12N15/10
CPC分类号： C12N15/102 , A01K67/0276 , A01K2217/00 , A01K2217/075 , C12N15/873 , C12N15/90 , C12N15/907
摘要： A method for altering one or more nucleic acid target sequences,comprising introducing into a first eukaryotic cell in meiosis: clustered regularly interspaced short palindromic repeats (CRISPR) associated protein 9 (Cas9) protein, or DNA or RNA encoding Cas9 (hereafter simply Cas9);and Cas9 guide RNA (gRNA) that hybridises to the target sequence(s).
摘要翻译：一种用于改变一个或多个核酸靶序列的方法，包括将减数分裂中的第一个真核细胞引入：聚集的定期交织的短回文重复序列（CRISPR）相关蛋白9（Cas9）蛋白，或编码Cas9（以下简称为Cas9）的DNA或RNA ;和与目标序列杂交的Cas9引导RNA（gRNA）。

6. 发明申请

WO2016055519A1 ENDOGENOUS RETROVIRUS TRANSCRIPTION AS A MARKER FOR PRIMATE NAÏVE PLURIPOTENT STEM CELLS 审中-公开
标题翻译：作为初始标记的内源性逆转录酶转录物可产生大量干细胞
公开(公告)号：WO2016055519A1
公开(公告)日：2016-04-14
申请号：PCT/EP2015/073144
申请日：2015-10-07
申请人： MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN , UNIVERSITY OF BATH
发明人： WANG, Jichang , IZSVÁK, Zsuzsanna , HURST, Laurence D.
IPC分类号： C12N5/0735 , C12N5/074
CPC分类号： C12N5/0606 , C12N5/0696 , C12N2500/90 , C12N2500/98 , C12N2501/065 , C12N2501/115 , C12N2501/15 , C12N2501/155 , C12N2501/16 , C12N2501/2306 , C12N2501/2311 , C12N2501/235 , C12N2501/33 , C12N2501/41 , C12N2501/415 , C12N2501/42 , C12N2501/727 , C12N2510/00
摘要： The present invention relates to the use of one or more type 7 long terminal repeat (LTR7) nucleic acid sequences of type H human endogenous retroviruses (HERVH) ("LTR7/HERVH nucleic acid sequences") for identifying primate naive pluripotent stem cells. The invention is directed to the use of LTR7/HERVH nucleic acid sequences as a marker, wherein LTR7/HERVH-associated transcription is used as a marker for primate naive pluripotent stem cells. The invention also relates to a reporter construct comprising LTR7/HERVH nucleic acid sequences in addition to the use of said reporter, in particular for optimizing culture conditions for naïve primate pluripotent stem cells. The invention also relates to a cell growth medium for cultivation of primate naive pluripotent stem cells that preferably exhibit elevated levels of LTR7/HERVH-associated transcription in comparison to control cells.
摘要翻译：本发明涉及H型人内源性逆转录病毒（HERVH）（“LTR7 / HERVH核酸序列”）的一种或多种7型长末端重复序列（LTR7）核酸序列用于鉴定灵长类天真多能干细胞的用途。本发明涉及使用LTR7 / HERVH核酸序列作为标记物，其中LTR7 / HERVH相关转录用作灵长类动物幼稚多能干细胞的标记物。除了使用所述报道基因之外，本发明还涉及包含LTR7 / HERVH核酸序列的报告基因构建体，特别是用于优化初始灵长类动物多能干细胞的培养条件。本发明还涉及用于培养灵长类动物幼体多能干细胞的细胞生长培养基，与对照细胞相比，其优选表现出升高的LTR7 / HERVH相关转录水平。

7. 发明申请

WO2014184536A1 APPARATUS AND METHOD FOR MEASURING ELECTROMAGNETIC PROPERTIES 审中-公开
标题翻译：用于测量电磁特性的装置和方法
公开(公告)号：WO2014184536A1
公开(公告)日：2014-11-20
申请号：PCT/GB2014/051460
申请日：2014-05-13
申请人： THE UNIVERSITY OF BATH
发明人： SOLEIMANI, Manuchehr
IPC分类号： G01N27/02 , G01N27/22
CPC分类号： G01N27/22 , G01N27/02 , G01N27/025 , G01N27/221
摘要： At least one of apparatus (100, 400) and a method for determining one or more electromagnetic properties of a region of interest are described. One or more inductive measurements (410) corresponding to the region of interest and one or more capacitive measurements (420) corresponding to the region of interest are received. An estimate of electrical conductivity is obtained(430) based on at least the received one or more inductive measurements(410). This is used to determine a permittivity measurement (440) together with at least the received one or more capacitive measurements(420).
摘要翻译：描述装置（100,400）中的至少一个以及用于确定感兴趣区域的一个或多个电磁特性的方法。接收对应于感兴趣区域的一个或多个感应测量（410）和对应于感兴趣区域的一个或多个电容测量（420）。至少基于所接收的一个或多个感应测量（410）获得电导率的估计（430）（430）。这用于确定介电常数测量（440）以及至少所接收的一个或多个电容测量（420）。

8. 发明申请

WO2010070300A3 THIOL-FUNCTIONALISING REAGENTS AND THEIR USES 审中-公开
公开(公告)号：WO2010070300A3
公开(公告)日：2010-06-24
申请号：PCT/GB2009/002924
申请日：2009-12-21
申请人： THE UNIVERSITY OF BATH , WATTS, Andrew, Graham , KANTNER, Terrence , MACKENZIE, Amanda, Barbara
发明人： WATTS, Andrew, Graham , KANTNER, Terrence , MACKENZIE, Amanda, Barbara
IPC分类号： C07K1/13 , A61K47/48
摘要： Reagents and methods for functionalising polypeptides with moieties poly (alkylene glycol) molecules and glycan groups are disclosed that are based on a functionalising reagent which comprises a nitrogen containing heterocyclic aromatic ring having a vinyl substituent that is capable of reacting with one or more thiol groups that are naturally present, or have been introduced into, the polypeptide, for example by employing a thiol group of one or more cysteine residues. The functionalising reagent is covalently linked to a poly (alkylene glycol) molecule, such as a polyethylene glycol (PEG) molecule, or a glycan group so that the reaction between the vinyl group and the thiol group in the polypeptide covalently links the polypeptide to the poly (alkylene glycol) molecule and/or the glycan group.

9. 发明申请

WO2009125188A1 A SENSOR 审中-公开
标题翻译：传感器
公开(公告)号：WO2009125188A1
公开(公告)日：2009-10-15
申请号：PCT/GB2009/000931
申请日：2009-04-09
申请人： UNIVERSITY OF BATH , TAYLOR, John, Tudor , HAO, Shiying , MILES, Anthony, William
发明人： TAYLOR, John, Tudor , HAO, Shiying , MILES, Anthony, William
IPC分类号： A61B5/00 , A61B5/07 , G01D5/22 , G01D18/00
CPC分类号： A61B5/076 , A61B5/0031 , A61B5/11 , A61B5/4504 , A61B5/4528 , A61B5/6846 , A61B5/6878 , A61B2560/0219 , G01D5/2291 , G01D18/008
摘要： A movement sensor comprises first and second movement components movable relative to each other about an equilibrium position and a sensor component arranged to sense the relative positions of the first and second movement components. The sensor further comprises a processor arranged to identify an equilibrium state of said movement components and set the corresponding position of the movement component as the equilibrium position.
摘要翻译：移动传感器包括围绕平衡位置相对于彼此移动的第一和第二移动部件以及布置成感测第一和第二移动部件的相对位置的传感器部件。传感器还包括处理器，其被布置成识别所述运动部件的平衡状态，并将运动部件的对应位置设置为平衡位置。

10. 发明申请

WO2008040999A2 APPARATUS AND PROCESS FOR USE IN THREE-PHASE CATALYTIC REACTIONS 审中-公开
标题翻译：在三相催化反应中使用的装置和方法
公开(公告)号：WO2008040999A2
公开(公告)日：2008-04-10
申请号：PCT/GB2007/003794
申请日：2007-10-05
申请人： THE UNIVERSITY OF BATH , KOLACZKOWSKI, Stanislaw, Tadeusz
发明人： KOLACZKOWSKI, Stanislaw, Tadeusz
IPC分类号： B01J8/04 , B01J10/00 , B01J19/24 , B01J19/28
CPC分类号： B01J19/285 , B01J8/0453 , B01J8/0496 , B01J10/007 , B01J19/249 , C07C45/38 , C07C47/54
摘要： A reactor for carrying out a heterogeneously catalysed reaction comprises at least first and second reaction zones (5, 6 7) arranged in series and each comprising catalytic material, heat transfer zones (8, 9, 10) located between said serially arranged reaction zones, and a pulse-generating device (14), which is arranged to deliver pulses to liquid in the reactor. The reactor allows three-phase reactions to be carried out efficiently and can reduce the impact of deposited reaction by- products on reaction efficiency.
摘要翻译：用于进行非均相催化反应的反应器包括至少串联布置的第一和第二反应区（5,6,7），每个包括催化材料，位于所述连续排列的反应区之间的传热区（8,9,10）以及脉冲发生装置（14），其布置成在反应器中向液体输送脉冲。反应器可以有效地进行三相反应，并可以减少沉积的反应副产物对反应效率的影响。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式