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1. 发明申请

WO2004017261A2 METHOD OF COLOR ACCENTUATION 审中-公开
标题翻译：色彩增强方法
公开(公告)号：WO2004017261A2
公开(公告)日：2004-02-26
申请号：PCT/US0325692
申请日：2003-08-18
申请人： SMITH PAUL REED GUITARS LTD , SMITH PAUL REED , GILBERT GARY E , SABETY TED
发明人： SMITH PAUL REED , GILBERT GARY E , SABETY TED
IPC分类号： G06T11/00 , H04N1/60 , H04N9/31 , G06T
CPC分类号： H04N9/3123 , G06T11/001 , H04N1/6027 , H04N9/3182
摘要： The color accentuation method determines the relative magnitude of each color component in each pixel or area. T selects and adjusts the magnitude of one or more of the colors as a function of the determined relative magnitudes of each color component. The type and amount of the adjustment may be a function of the relative magnitude differences. One or more of the magnitudes is adjusted to change the relative magnitudes. Typically, the difference in a subtractive color space s between the lowest and middle magnitude color and n an additive color space is between the highest and the middle magnitude color. Also, typically, the lowest color component s reduced in the subtractive color space and the highest is increased in the additive color space. Various scaling functions and compensations or adjustments of the color accentuation may be used.
摘要翻译：颜色增强方法确定每个像素或区域中每个颜色分量的相对量值。 T根据所确定的每个颜色分量的相对量值来选择和调整一种或多种颜色的大小。调整的类型和数量可能是相对幅度差异的函数。一个或多个幅度被调整以改变相对幅度。通常情况下，最低和中等幅度色彩与添加色彩空间之间的相减色彩空间差异介于最高和中等幅度色彩之间。而且，典型地，在相减色彩空间中减小的最低色彩分量s和在加性色彩空间中最高色彩分量增加。可以使用各种缩放功能和颜色加重的补偿或调整。

2. 发明申请

WO0217229A8 METHOD OF COLOR ACCENTUATION 审中-公开
标题翻译：颜色识别方法
公开(公告)号：WO0217229A8
公开(公告)日：2003-08-14
申请号：PCT/US0125654
申请日：2001-08-17
申请人： SMITH PAUL REED GUITARS LTD , SMITH PAUL REED
发明人： SMITH PAUL REED
IPC分类号： G06T1/00 , G06T5/00 , G06T11/00 , H04N1/46 , H04N1/60 , H04N9/68 , B44C1/16
CPC分类号： G06T11/001 , H04N1/6008 , H04N1/6027
摘要： The accentuation method (20) determines the relative magnitude (Fig. 3, S 1-4) of each color component. It selects (24) and adjusts (26) the magnitude of one or more of the colors as a function of the determined relative magnitudes (Fig.3, S 1-4) of each color component. The type and amount of the adjustment (26) is a function of the relative magnitude (Fig. 3, S 1-4) differences. One or more of the magnitudes (Fig. 3, S 1-4) is adjusted (26) to change the relative magnitudes (Fig. 3, S 1-4). Typically, the differences in the subtractive color space is between the lowest and middle magnitude color. Also, typically, the lowest primary color component is reduced.
摘要翻译：强调方法（20）确定每个颜色分量的相对幅度（图3，S 1-4）。它根据每个颜色分量的确定的相对幅度（图3，S 1-4）选择（24）并调整（26）一种或多种颜色的大小。调整（26）的类型和数量是相对值的函数（图3，S 1-4）的差异。一个或多个量值（图3，S 1-4）被调整（26）以改变相对幅度（图3，S 1-4）。通常，减色区域的差异在最低和中等幅度的颜色之间。此外，通常，最低的原色成分减少。

3. 发明申请

WO0217229A3 METHOD OF COLOR ACCENTUATION 审中-公开
标题翻译：色彩增强方法
公开(公告)号：WO0217229A3
公开(公告)日：2002-05-16
申请号：PCT/US0125654
申请日：2001-08-17
申请人： SMITH PAUL REED GUITARS LTD , SMITH PAUL REED
发明人： SMITH PAUL REED
IPC分类号： G06T1/00 , G06T5/00 , G06T11/00 , H04N1/46 , H04N1/60 , H04N9/68 , B44C1/16
CPC分类号： G06T11/001 , H04N1/6008 , H04N1/6027
摘要： The accentuation method (20) determines the relative magnitude (Fig. 3, S 1-4) of each color component. It selects (24) and adjusts (26) the magnitude of one or more of the colors as a function of the determined relative magnitudes (Fig.3, S 1-4) of each color component. The type and amount of the adjustment (26) is a function of the relative magnitude (Fig. 3, S 1-4) differences. One or more of the magnitudes (Fig. 3, S 1-4) is adjusted (26) to change the relative magnitudes (Fig. 3, S 1-4). Typically, the differences in the subtractive color space is between the lowest and middle magnitude color. Also, typically, the lowest primary color component is reduced.
摘要翻译：强调方法（20）确定每个颜色分量的相对量值（图3，S1-4）。它根据每个颜色分量的确定的相对量值（图3，S1-4）选择（24）并调整（26）一种或多种颜色的量值。调整的类型和数量（26）是相对幅度（图3，S 1-4）差异的函数。调整一个或多个幅度（图3，S 1-4）（26）以改变相对幅度（图3，S 1-4）。通常，相减色彩空间的差异在最低和中等大小的色彩之间。而且，通常，最低的原色分量被减少。

4. 发明申请

WO0186631A3 ANALYSIS OF AND NOISE REDUCTION IN A COMPLEX WAVEFORM 审中-公开
标题翻译：复杂波形中的分析和噪声减少
公开(公告)号：WO0186631A3
公开(公告)日：2002-03-21
申请号：PCT/US0140664
申请日：2001-05-04
申请人： SMITH PAUL REED GUITARS LTD , SMITH JACK W , SMITH PAUL REED , GILBERT GARY E
发明人： SMITH JACK W , SMITH PAUL REED , GILBERT GARY E
IPC分类号： G10K11/16 , G10K15/02 , G10L21/0208 , G10L21/0232 , G10L21/00
CPC分类号： G10L21/0208 , G10K11/16 , G10K15/02 , G10L21/0232
摘要： A method is provided for analysis and noise reduction in a complex waveform using the methods of Fast Find, Harmonic Adjustment and Partial Accentuation. The Fast Find method determines the harmonic content of each tone spectra in the complex waveform. The Harmonic Adjustment method amplifies harmonics in the tone spectra below a crossover frequency. The Partial Accentuation amplifies partials in the complex waveform above the crossover frequency. A Partial Consolidation method consolidates partials by frequency and time into narrow, short term frequency bands for modification by Partial/Resonant Band Accentuation. By combining these methods, noise reduction, audio clarification and other audio enhancements and characterizations are accomplished.
摘要翻译：提供了一种使用快速查找，谐波调整和部分重音的方法在复杂波形中进行分析和降噪的方法。快速查找方法确定复合波形中每个色谱的谐波含量。谐波调整方法将色调谱中的谐波放大到交叉频率以下。部分浓度放大在交叉频率以上的复杂波形中的部分。部分合并方法将部分频率和时间合并到狭窄的短期频段，以通过部分/谐振频带重音进行修改。通过组合这些方法，可以实现降噪，音频澄清和其他音频增强和特性化。

5. 发明申请

WO2005020130A3 METHOD OF COLOR ACCENTUATION WITH COMPENSATION AND ADJUSTMENT 审中-公开
标题翻译：彩色识别与补偿和调整方法
公开(公告)号：WO2005020130A3
公开(公告)日：2005-05-19
申请号：PCT/US2004005640
申请日：2004-02-26
申请人： SMITH PAUL REED GUITARS LTD , SMITH PAUL REED , GILBERT GARY E , SABETY TED
发明人： SMITH PAUL REED , GILBERT GARY E , SABETY TED
IPC分类号： G06K20060101 , G06K9/00 , G06K9/40
CPC分类号： H04N9/646 , H04N1/6016
摘要： The color accentuation method determines the relative magnitude of each color component in each (34a, 34b). It selects and adjusts the magnitude of one or more of the colors as a function of the determined relative magnitudes of each color component. The type and amount of the adjustment is a function of the relative magnitude differences (40a, 40b). One or more of the magnitudes is adjusted to change the relative magnitudes. Typically, the difference in a subtractive color space is between the lowest and middle magnitude color (36b) and in an additive color space is between the highest and the middle magnitude color (36a). Also, typically, the lowest color component is reduced in the subtractive color space and the highest is increased in the additive color space. Various scaling functions (38a, 38b) and compensations or adjustments (42a, 42b) of the color accentuation may be used.
摘要翻译：颜色突出方法确定每个（34a，34b）中每个颜色分量的相对大小。它根据确定的每个颜色分量的相对幅度来选择和调整一种或多种颜色的大小。调整的类型和量是相对幅值差（40a，40b）的函数。调整一个或多个量值以改变相对幅度。通常，减色区域的差异在最低和中等幅度颜色（36b）之间，而在加性颜色空间中是最高和中等幅度颜色（36a）之间。此外，通常，减色色彩空间中最低色彩成分减少，而在添加色空间中最高色成分增加。可以使用颜色增强的各种缩放功能（38a，38b）和补偿或调整（42a，42b）。

6. 发明申请

WO2016164407A2 DETECTION OF ONE OR MORE PATHOGENS 审中-公开
标题翻译：检测一种或多种病原体
公开(公告)号：WO2016164407A2
公开(公告)日：2016-10-13
申请号：PCT/US2016/026140
申请日：2016-04-06
申请人： POLYSKOPE LABS , ZEGRATI, Cyrus Cody , CENTOLA, Michael Benjamin , GRAMLING, JR., Bobby Alfonso , SMITH, Paul Simon
发明人： ZEGRATI, Cyrus Cody , CENTOLA, Michael Benjamin , GRAMLING, JR., Bobby Alfonso , SMITH, Paul Simon
IPC分类号： C12Q1/70 , C12Q1/68
CPC分类号： C12Q1/689 , C12Q2600/16
摘要： Provided herein are media, methods, kits, primers and oligonucleotide probes for use in the molecular detection of pathogens. These may be used in combination for the rapid, high-throughput screening PCR-based techniques to simultaneously detect multiple pathogens. The multiplex-detection methods have improved sensitivity and specificity for the detection of multiple pathogens simultaneously. Real-time PCR assaying techniques using such primers include microarrays and multiplex arrays, the latter optionally simultaneously with oligonucleotide TaqMan probes.
摘要翻译：本文提供了用于病原体分子检测的培养基，方法，试剂盒，引物和寡核苷酸探针。这些可以组合用于快速，高通量筛选基于PCR的技术以同时检测多种病原体。多重检测方法同时提高了对多种病原体的检测灵敏度和特异性。使用这种引物的实时PCR测定技术包括微阵列和多重阵列，后者任选与寡核苷酸TaqMan探针同时进行。

7. 发明申请

WO2016059571A1 COMBINATIONS COMPRISING SIPONIMOD AND LAQUINIMOD FOR THE TREATMENT OF MULTIPLE SCLEROSIS 审中-公开
标题翻译：包含SIPONIMOD和LAQUINIMOD治疗多发性硬化症的组合
公开(公告)号：WO2016059571A1
公开(公告)日：2016-04-21
申请号：PCT/IB2015/057870
申请日：2015-10-14
申请人： NOVARTIS AG , SMITH, Paul Alfred
发明人： SMITH, Paul Alfred
IPC分类号： A61K31/397 , A61K31/4704 , A61P37/00
CPC分类号： A61K31/4704 , A61K31/397 , A61K2300/00
摘要： The present invention relates to combinations and pharmaceutical compositions comprising siponimod and laquinimod, and the use of said combinations and/or compositions for the treatment of multiple sclerosis, particularly secondary progressive multiple sclerosis.
摘要翻译：本发明涉及包含西来莫多和拉喹莫德的组合和药物组合物，以及所述组合和/或组合物用于治疗多发性硬化症，特别是继发性进行性多发性硬化症的用途。

8. 发明申请

WO2014037900A1 INDOLE CARBOXAMIDE DERIVATIVES AND USES THEREOF 审中-公开
标题翻译：包含羧酰胺衍生物及其用途
公开(公告)号：WO2014037900A1
公开(公告)日：2014-03-13
申请号：PCT/IB2013/058318
申请日：2013-09-05
申请人： NOVARTIS AG , JIRICEK, Jan , KONDREDDI, Ravinder Reddy , SMITH, Paul William
发明人： JIRICEK, Jan , KONDREDDI, Ravinder Reddy , SMITH, Paul William
IPC分类号： C07D209/42 , A61K31/403 , A61P31/06
CPC分类号： C07D209/42 , A61K31/404 , A61K31/4045 , A61K31/407 , A61K31/454 , A61K31/5377 , A61K45/06 , C07D491/056
摘要： A compound of Formula (I) is provided that has been shown to be useful for treating a disease, disorder or syndrome that is mediated by the transportation of essential molecules in the mmpL3 pathway: (I) wherein R 1 , R 2 , R 3 , R 4 , R 5 and R 6 are as defined herein.
摘要翻译：提供了式（I）化合物，其已被证明可用于治疗通过在mmpL3途径中运输必需分子介导的疾病，病症或综合征：（I）其中R1，R2，R3，R4， R5和R6如本文所定义。

9. 发明申请

WO2013025901A2 FRAGRANT DEPILATORY ARTICLE 审中-公开
标题翻译：香格里拉消化文章
公开(公告)号：WO2013025901A2
公开(公告)日：2013-02-21
申请号：PCT/US2012/051129
申请日：2012-08-16
申请人： THE PROCTER & GAMBLE COMPANY , SMITH, Paul, James , PLOS, Julien, Claude , EVANGELISTA, Olindo , SAGEL, Paul, Albert , PASSI, Rajeev, Kumar , MITRA, Shekhar , BROYLES, Norman, Scott
发明人： SMITH, Paul, James , PLOS, Julien, Claude , EVANGELISTA, Olindo , SAGEL, Paul, Albert , PASSI, Rajeev, Kumar , MITRA, Shekhar , BROYLES, Norman, Scott
IPC分类号： A61K8/11 , A61Q9/00 , A61Q13/00 , A45D37/00
CPC分类号： A61Q9/04 , A61K8/0208 , A61K8/0241 , A61K8/8135 , A61K2800/56 , A61K2800/654
摘要： A depilatory article comprising a substrate and a depilatory composition disposed on said substrate wherein the depilatory composition comprises solid entrapping particles, said particles comprising a polymer and a volatile material or mixture of volatile materials.
摘要翻译：包含基材和置于所述基材上的脱毛剂组合物的脱毛剂制品，其中所述脱毛剂组合物包含固体包埋颗粒，所述颗粒包含聚合物和挥发性物质或挥发性物质的混合物。

10. 发明申请

WO2013025896A3 DEPILATORY METHOD AND KIT 审中-公开
公开(公告)号：WO2013025896A3
公开(公告)日：2013-02-21
申请号：PCT/US2012/051122
申请日：2012-08-16
申请人： THE PROCTER & GAMBLE COMPANY , SMITH, Paul, James , TRANI, Marina , JAKUBOVIC, David, Andrew , DRING, Neil, Charles
发明人： SMITH, Paul, James , TRANI, Marina , JAKUBOVIC, David, Andrew , DRING, Neil, Charles
IPC分类号： A61K8/46 , A61Q9/04 , A61K8/81 , A61K8/02
摘要： A depilatory kit is provided comprising: (a) a depilatory composition comprising an effective amount of a keratin reducing agent; (b) a sheet of occlusive material which is separate from the depilatory composition.

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