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    • 3. 发明申请
    • BALLOON CATHETER FOR DELIVERING A THERAPEUTIC AGENT
    • 用于递送治疗剂的气囊导管
    • WO2009036135A1
    • 2009-03-19
    • PCT/US2008/075970
    • 2008-09-11
    • COOK INCORPORATEDSCHAEFFER, Darin, G.LENTZ, David, Christian
    • SCHAEFFER, Darin, G.LENTZ, David, Christian
    • A61M25/10
    • A61M25/10A61M25/1027A61M2025/0004A61M2025/1013A61M2025/105A61M2025/1056
    • Catheter balloon assemblies (10) for delivering a therapeutic agent to a body vessel are provided, as well as related methods of manufacturing and methods of treatment. The catheter balloon assemblies may include a concentrically disposed dual balloon assembly at the distal portion of the catheter having an inner balloon (44), a porous outer balloon (42) concentrically arrayed around the inner balloon and a catheter shaft (30) adapted to deliver a therapeutic agent to the body vessel through the apertures in the outer balloon. Radial outward expansion of the inner balloon may urge the outer balloon into contact with the wall of a body vessel, where the therapeutic agent may be delivered from the catheter shaft through apertures in the outer balloon directly to the wall of the body vessel. Preferably, the catheter balloon assemblies include a stiffening' member (210) within the proximal portion and/or a plurality of lumens lined with a fluorinated hydrocarbon to independently inflate the inner balloon, deliver the therapeutic agent through the outer balloon and house a wire guide (50). The catheter balloon assemblies may provide improved tractability and/or pushability characteristics.
    • 提供了用于将治疗剂递送至身体血管的导管气囊组件(10),以及相关的制造方法和治疗方法。 导管球囊组件可以包括在导管的远端部分处的同心设置的双球囊组件,其具有内球囊(44),围绕内球囊同心排列的多孔外球囊(42)和适于递送的导管轴 通过外球囊中的孔,向身体血管施加治疗剂。 内球囊的径向向外膨胀可以促使外球囊与体血管的壁接触,其中治疗剂可以通过外球囊中的孔直接从导管轴输送到身体血管的壁。 优选地,导管球囊组件包括近端部分内的加强构件(210)和/或内衬有氟化烃的多个内腔,以独立地使内球囊充气,通过外球囊输送治疗剂并容纳导线 (50)。 导管球囊组件可以提供改善的易处理性和/或可推动性特征。