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1. 发明申请

WO1996012808A1 NUCLEIC ACID PREPARATION FOR IMMUNIZATION AND METHOD FOR IMMUNIZATION USING THE SAME 审中-公开
标题翻译：用于免疫的核酸准备和使用该免疫的免疫方法
公开(公告)号：WO1996012808A1
公开(公告)日：1996-05-02
申请号：PCT/JP1995002134
申请日：1995-10-18
申请人： JURIDICAL FOUNDATION THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE , SAKAGUCHI,Masashi , SONODA, Kengo , MATSUO, Kazuo , HAMADA, Fukusaburo
发明人： JURIDICAL FOUNDATION THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE
IPC分类号： C12N15/45
CPC分类号： C07K14/005 , A61K2039/51 , A61K2039/53 , C12N15/87 , C12N2760/18122
摘要： The present invention relates to a nucleic acid preparation for immunization of an animal, comprising a linearized DNA which comprises a promoter for expression of a gene functioning in an animal cell and a gene coding for an immunizing antigen derived from a pathogen linked to the downstream of said promoter; and a method for immunizing an animal utilizing said nucleic acid preparation. Specifically, this invention relates to the immunization of poultry with a DNA coding for Newcastle disease virus (NDV)-F protein under the control of an improved chicken beta-actin promoter.
摘要翻译：本发明涉及用于免疫动物的核酸制剂，其包含线性化DNA，其包含用于表达在动物细胞中起作用的基因的启动子和编码来自与下游相连的病原体的免疫抗原的基因所说的启动子以及利用所述核酸制剂免疫动物的方法。具体地说，本发明涉及在改良的鸡β-肌动蛋白启动子的控制下用编码新城疫病毒（NDV）-F蛋白的DNA免疫家禽。

2. 发明申请

WO1998012331A1 NOVEL POLYPEPTIDE ORIGINATING IN HEMOPHILUS PARAGALLINARUM AND PROCESS FOR PRODUCING THE SAME 审中-公开
标题翻译：新型多肽在海参中的定性及其生产方法
公开(公告)号：WO1998012331A1
公开(公告)日：1998-03-26
申请号：PCT/JP1997003222
申请日：1997-09-12
申请人： JURIDICAL FOUNDATION THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE , TOKUNAGA, Eiji , SAKAGUCHI, Masashi , MATSUO, Kazuo , HAMADA, Fukusaburo , TOKIYOSHI, Sachio
发明人： JURIDICAL FOUNDATION THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE
IPC分类号： C12N15/31
CPC分类号： C07K14/285 , A61K38/00 , A61K39/00 , Y10S435/851
摘要： A novel polypeptide originating in Hemophilus paragallinarum which is useful in inhibiting chick infectious coryza. The above-mentioned polypeptide which induces the HI antibody production so as to prevent the infection and onset of chick infectious coryza; a gene encoding this polypeptide; a recombinant vector for expressing this gene; a host transformed by this vector; a process for the production of the polypeptide by the host; a chick infectious coryza vaccine containing as the main ingredient the above-mentioned polypeptide; a monoclonal antibody obtained by using the polypeptide as the immunogen; and diagnostic agents and remedies for chick infectious disease with the use of the above-mentioned polypeptide and antibody.
摘要翻译：源自嗜血杆菌的新型多肽可用于抑制鸡感染性鼻炎。上述引起HI抗体产生以防止感染和发作鸡感染性鼻炎的多肽; 编码该多肽的基因; 用于表达该基因的重组载体; 由该载体转化的宿主由宿主生产多肽的方法; 含有上述多肽的主要成分的鸡感染性鼻炎疫苗; 通过使用该多肽作为免疫原获得的单克隆抗体; 以及使用上述多肽和抗体的鸡感染性疾病的诊断剂和治疗药物。

3. 发明申请

WO1997031066A1 CURABLE COMPOSITION 审中-公开
标题翻译：可固化组合物
公开(公告)号：WO1997031066A1
公开(公告)日：1997-08-28
申请号：PCT/JP1997000485
申请日：1997-02-21
申请人： KANEKA CORPORATION , CHIBA, Makoto , OKAMOTO, Toshihiko , SAKAGUCHI, Masashi , TAKASE, Junji
发明人： KANEKA CORPORATION
IPC分类号： C08L101/10
CPC分类号： C08F8/42 , C09K3/1018
摘要： A curable composition comprising a saturated hydrocarbon polymer having reactive silicon groups and giving products of curing excellent in adhesion under exposure to light. This composition comprises: (A) a saturated hydrocarbon polymer having reactive silico n groups, (B) a light stabilizer containing nickel, and (C) a silane coupling agent.
摘要翻译：一种可固化组合物，其包含具有反应性硅基团的饱和烃聚合物，并产生在曝光下粘合性优异的产品。该组合物包括：（A）具有反应性硅基n基团的饱和烃聚合物，（B）含镍的光稳定剂和（C）硅烷偶联剂。

4. 发明申请

WO1996038565A1 RECOMBINANT HERPESVIRUS WITH THE USE OF gB GENE PROMOTER 审中-公开
标题翻译：使用gB基因促进剂的重组草药
公开(公告)号：WO1996038565A1
公开(公告)日：1996-12-05
申请号：PCT/JP1996001428
申请日：1996-05-28
申请人： JURIDICAL FOUNDATION THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE , SONODA, Kengo , SAKAGUCHI, Masashi , MATSUO, Kazuo , HAMADA, Fukusaburo
发明人： JURIDICAL FOUNDATION THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE
IPC分类号： C12N15/38
CPC分类号： C12N15/86 , A61K2039/53 , C07K14/005 , C12N2710/16343 , C12N2760/18122 , Y10S424/816
摘要： A recombinant Herpesvirus capable of effectively expressing the target alien protein in a host animal which has been inoculated therewith and exerting an excellent immunological effect. The recombinant Herpesvirus has an alien gene expression cassette integrated thereinto wherein a gB gene originating in Herpesvirus (a gene homologous with Herpes simplex virus gB gene) promoter is employed as a promoter for the expression of the alien gene.
摘要翻译：一种重组疱疹病毒能够有效地表达目标异源蛋白质的宿主动物中已被接种并具有优异的免疫学作用。重组疱疹病毒具有整合在其中的外源基因表达盒，其中使用源自疱疹病毒（与单纯疱疹病毒gB基因同源的基因）启动子的gB基因作为外源基因表达的启动子。

5. 发明申请

WO1997031032A1 CURABLE COMPOSITION 审中-公开
标题翻译：可固化组合物
公开(公告)号：WO1997031032A1
公开(公告)日：1997-08-28
申请号：PCT/JP1997000357
申请日：1997-02-12
申请人： KANEKA CORPORATION , OKAMOTO, Toshihiko , CHIBA, Makoto , SAKAGUCHI, Masashi , TAKASE, Junji
发明人： KANEKA CORPORATION
IPC分类号： C08F02/44
CPC分类号： C09K3/1018 , C08F8/42
摘要： A curable composition which is composed mainly of a saturated hydrocarbon polymer having a reactive silicon group and can improve the adhesion to various adherents and various types of glass, particularly weather-resistant adhesion to heat reflecting glass. The curable composition comprises (A) a saturated hydrocarbon polymer having a hydroxyl group or a hydrolyzable group bonded to a silicon atom and at least one silicon-containing group crosslinkable through the formation of a siloxane bond, (B) a silane coupling agent, and (C) a compound having in its molecule an unsaturated group polymerizable upon a reaction with oxygen in the air and/or a photopolymerizable material.
摘要翻译：一种主要由具有反应性硅基团的饱和烃聚合物组成的可固化组合物，可以改善对各种粘合剂和各种类型的玻璃的粘合性，特别是对耐热反射玻璃的耐候性。可固化组合物包含（A）具有与硅原子键合的羟基或可水解基团的饱和烃聚合物和至少一个可通过形成硅氧烷键交联的含硅基团，（B）硅烷偶联剂和（C）在其分子中具有与空气中的氧反应可聚合的不饱和基团和/或可光聚合材料的化合物。

6. 发明申请

WO1996021633A1 COMPOSITION FOR DOUBLE-GLAZING UNIT 审中-公开
标题翻译：双层玻璃组合物
公开(公告)号：WO1996021633A1
公开(公告)日：1996-07-18
申请号：PCT/JP1996000029
申请日：1996-01-11
申请人： KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA , CHIBA, Makoto , SAKAGUCHI, Masashi
发明人： KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA
IPC分类号： C03C27/06
CPC分类号： C09K3/1018 , B32B17/1055 , C03C27/10 , C08L2666/02 , C09J123/02 , C09J123/22 , C09K2200/0458 , C09K2200/0476 , C09K2200/0617
摘要： A composition for double-glazing units, which satisfies the requirement of low moisture-permeability and weather-resistant adhesiveness, has a rapid-hardenability by means of addition-type hardening, is capable of production on a production line, and can be used also as a one-pack sealing agent having good shelf stability and mechanical strengths. The composition contains as the essential ingredients (A) a hydrocarbon polymer having at least one alkenyl group in its monomer molecule and a molecular weight of 500 to 300,000, (B) a hardening agent having at least two silyl groups in its molecule, (C) a hydrosilylating agent, and (D) a tackifier. In addition to the ingredients (A) to (D), it contains (E) a shelf stability improver to provide a one-pack sealing agent. Preferable examples of the ingredients (A) and (B) are, respectively, an isobutylene polymer and a polyorganohydrogensiloxane.
摘要翻译：用于双层玻璃单元的组合物，其满足低透湿性和耐候性粘合性的要求，通过添加型硬化具有快速淬透性，能够在生产线上生产，并且还可以使用作为具有良好的储存稳定性和机械强度的单组分密封剂。该组合物含有作为必要成分（A）在其单体分子中具有至少一个烯基的烃聚合物，分子量为500〜300,000，（B）分子中具有至少2个甲硅烷基的硬化剂，（C ）氢化硅烷化剂，和（D）增粘剂。除了成分（A）至（D）之外，它还含有（E）保存稳定性改进剂以提供单组份密封剂。成分（A）和（B）的优选实例分别是异丁烯聚合物和聚有机氢硅氧烷。

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