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1. 发明申请

WO2012069610A1 ASSAY DEVICE 审中-公开
标题翻译：测试设备
公开(公告)号：WO2012069610A1
公开(公告)日：2012-05-31
申请号：PCT/EP2011/070985
申请日：2011-11-24
申请人： SPD SWISS PRECISION DIAGNOSTICS GMBH , RAJ, Balbir , EAPEN, Saji , SCRIMGEOUR, Ian
发明人： RAJ, Balbir , EAPEN, Saji , SCRIMGEOUR, Ian
IPC分类号： G01N33/543 , G01N33/558
CPC分类号： G01N33/76 , G01N33/54366 , G01N33/558
摘要： The present invention relates generally to an assay device with improved tolerance to mishandling and/or improper use by the user. More particularly, the invention relates to an assay device with reduced susceptibility to flooding.
摘要翻译：本发明一般涉及具有改进的误操作和/或用户使用不当的耐受性的测定装置。更具体地，本发明涉及具有降低的淹水敏感性的测定装置。

2. 发明申请

WO2010073010A3 CONTAINER CLOSURE SYSTEM INVOLVING MAGNETIC OPENING INTERACTION 审中-公开
公开(公告)号：WO2010073010A3
公开(公告)日：2010-07-01
申请号：PCT/GB2009/002944
申请日：2009-12-22
申请人： ACCREDIT INNOVATIONS LIMITED , RAJ, Balbir , SMART, Dave
发明人： RAJ, Balbir , SMART, Dave
IPC分类号： B65D47/24 , B65D51/24
摘要： A container (1) having a closure system (2), the closure system having a moveable closure (6) biased in a closed position and a trigger device (11) said trigger device arranged to cause the closure to move from said closed position to an open position by virtue of a magnetic interaction.

3. 发明申请

WO2005059547A2 ASSAY 审中-公开
公开(公告)号：WO2005059547A2
公开(公告)日：2005-06-30
申请号：PCT/GB2004/005146
申请日：2004-12-10
申请人： INVERNESS MEDICAL SWITZERLAND GMBH , RAJ, Balbir
发明人： RAJ, Balbir
IPC分类号： G01N33/53
CPC分类号： G01N33/558 , G01N33/54306 , G01N33/54386 , G01N33/54393 , Y10S435/81
摘要： The present invention provides an assay kit for detecting an analyte of interest in a sample. The kit comprises a) a reporter species; b) a labeled species having first and second binding regions, wherein the first binding region is capable of binding to the analyte of interest and the second binding region is capable of binding to the reporter species; c) an immobilized species capable of binding to the first binding region of the labeled species; and d) immobilized capture reagent capable of binding to the reporter species. The arrangement is such that the sample is contacted with the labeled species, is then contacted with the immobilized species and is subsequently contacted with the immobilized capture reagent, the reporter species being added prior to exposure of the sample to the immobilized capture reagent. If no analyte is present in the sample, the labeled species becomes bound to the immobilized species and is therefore unable to bind to the immobilized capture reagent. If analyte is present in the sample, the analyte binds to the labeled species such that the labeled species is unable to bind to the immobilized species but can bind to the immobilized capture reagent via the reporter species, the presence of the analyte thus being determined by the presence of labeled species bound to the immobilized capture reagent via the reporter species.
摘要翻译：本发明提供了用于检测样品中感兴趣分析物的分析试剂盒。该试剂盒包含a）报道物种; b）具有第一和第二结合区的标记物质，其中所述第一结合区能够结合所述目的分析物，并且所述第二结合区能够结合所述报道物质; c）能够结合标记物质的第一结合区域的固定化物质; 和d）能够结合报道物质的固定化捕获试剂。该排列使得样品与标记的物质接触，然后与固定的物质接触并随后与固定的捕获剂接触，在将样品暴露于固定的捕获剂之前添加报道物质。如果样品中不存在分析物，则标记物质与固定化物质结合，因此不能与固定的捕获试剂结合。如果分析物存在于样品中，则分析物与标记物质结合，使得标记物质不能与固定化物质结合，但可以通过报道物质与固定的捕获试剂结合，因此分析物的存在由标记物质的存在通过报道物质与固定的捕获试剂结合。

4. 发明申请

WO2008040983A1 ASSAY DEVICE 审中-公开
标题翻译：测定装置
公开(公告)号：WO2008040983A1
公开(公告)日：2008-04-10
申请号：PCT/GB2007/003771
申请日：2007-10-05
申请人： UNIPATH LTD , RAJ, Balbir , BIRCH, Brian
发明人： RAJ, Balbir , BIRCH, Brian
IPC分类号： G01N33/543
CPC分类号： G01N33/5438
摘要： An assay device is provided for determining the presence and/or amount of an analyte in a fluid sample. The device has a fluid transporting means comprising a labelled binding reagent for the analyte, an analyte analogue or a binding reagent for the analyte, wherein said assay device comprises two or more sample activatable battery cells connected in series.
摘要翻译：提供了用于确定流体样品中分析物的存在和/或量的测定装置。该装置具有流体输送装置，其包含用于分析物的标记结合试剂，用于分析物的分析物类似物或结合试剂，其中所述测定装置包括串联连接的两个或更多样品可活化的电池单元。

5. 发明申请

WO2007110702A3 ASSAYS 审中-公开
公开(公告)号：WO2007110702A3
公开(公告)日：2007-10-04
申请号：PCT/IB2006/004158
申请日：2006-11-22
申请人： INVERNESS MEDICAL SWITZERLAND GMBH , RAJ, Balbir
发明人： RAJ, Balbir
IPC分类号： G01N33/558 , G01N33/58 , G01N33/76
摘要： Provided are assays and devices to detect a target compound in urine.

6. 发明申请

WO2005121800A2 IMPROVEMENTS IN OR RELATING TO LATERAL FLOW ASSAY DEVICES 审中-公开
标题翻译：改进或相关于侧流测试装置
公开(公告)号：WO2005121800A2
公开(公告)日：2005-12-22
申请号：PCT/GB2005/002266
申请日：2005-06-08
申请人： INVERNESS MEDICAL SWITZERLAND GMBH , RAJ, Balbir
发明人： RAJ, Balbir
IPC分类号： G01N33/558
CPC分类号： G01N33/558 , Y10T29/49826
摘要： Disclosed is an assay device for determining the presence or absence of an analyte of interest in a sample, the device comprising a test strip, the test strip having a reading zone wherein the result of the test may be observed; the device further comprising a movable portion which is movable from a first ("testing") position to a second ("reading") position; wherein, at the first position the movable portion obscures the reading zone, and wherein movement of the movable portion from the first position to the second position uncovers or reveals the reading zone, rendering the reading zone available for visual inspection.
摘要翻译：公开了一种用于确定样品中感兴趣分析物的存在或不存在的测定装置，该装置包括测试条，测试条具有读数区，其中可以观察到测试结果; 该装置还包括可从第一（“测试”）位置移动到第二（“读取”）位置的可移动部分; 其中，在所述第一位置，所述可移动部分遮蔽所述读取区域，并且其中所述可移动部分从所述第一位置到所述第二位置的移动露出或露出所述读取区域，使得所述读取区域可用于目视检查。

7. 发明申请

WO2008122796A1 ASSAY DEVICE 审中-公开
标题翻译：测定装置
公开(公告)号：WO2008122796A1
公开(公告)日：2008-10-16
申请号：PCT/GB2008/001227
申请日：2008-04-09
申请人： INVERNESS MEDICAL SWITZERLAND GMBH , RAJ, Balbir , EAPEN, Saji , LINLEY, Ezra
发明人： RAJ, Balbir , EAPEN, Saji , LINLEY, Ezra
IPC分类号： G01N33/558 , G01N33/68
CPC分类号： G01N33/76 , B01L2300/0825 , B01L2300/087 , B01L2400/0406 , C12Q2537/125 , G01N33/558 , G01N33/689 , Y10T29/494
摘要： Disclosed is an assay device for the determination of the presence and/or extent if an analyte in a liquid sample over an extended concentration range comprising a first assay and a second assay, wherein the first assay for an analyte comprises a first flow-path having a sole detection zone capable of immobilising a labelled binding reagent and the second assay for said analyte comprises a second flow- path having a sole detection zone capable of immobilising a labelled binding reagent, wherein the presence of labelled binding reagent at the detection zones provides an indication of the presence and/or extent of analyte in said liquid sample.
摘要翻译：公开了一种用于确定在包括第一测定和第二测定的扩展浓度范围内的液体样品中的分析物的存在和/或程度的测定装置，其中用于分析物的第一测定包括第一流动路径，其具有能够固定标记的结合试剂的唯一检测区域和用于所述分析物的第二测定物包括具有能够固定标记的结合试剂的唯一检测区域的第二流路，其中在检测区域处标记的结合试剂的存在提供了指示所述液体样品中分析物的存在和/或程度。

8. 发明申请

WO2008025945A1 FLUIDIC INDICATOR DEVICE 审中-公开
标题翻译：流体指示器装置
公开(公告)号：WO2008025945A1
公开(公告)日：2008-03-06
申请号：PCT/GB2007/003091
申请日：2007-08-14
申请人： INVERNESS MEDICAL SWITZERLAND GMBH , TOLLEY, David , RAJ, Balbir
发明人： TOLLEY, David , RAJ, Balbir
IPC分类号： B01L3/00
CPC分类号： G01N33/558 , B01L3/5023 , B01L3/5027 , B01L3/502723 , B01L3/502753 , B01L2200/0621 , B01L2200/148 , B01L2300/025 , B01L2300/0681 , B01L2300/0816 , B01L2300/0864 , B01L2400/0406 , G01N33/54366 , G01N33/76 , G01N2333/59 , Y10S436/807
摘要： Disclosed is a fluidic assay device for assaying at least one property of a liquid sample, the device comprising: (i) a liquid sample application region (2); (ii) at least one test flow path in liquid flow communication with the sample application region (4); (iii) a reference flow path in liquid flow communication with the sample application region (6); and (iv) a junction region (10), at which the test flow path and the reference flow path contact one another, the junction region typically comprising an outlet, conduit, chamber or other portion which permits the onward flow of liquid; wherein a liquid flowing along the reference flow path, upon reaching the junction region, has the effect of preventing the flow of liquid along the test flow path.
摘要翻译：公开了用于测定液体样品的至少一种性质的流体测定装置，该装置包括：（i）液体样品施加区域（2）; （ii）与样品施加区域（4）液体流动连通的至少一个测试流动路径; （iii）与样品施加区域（6）的液体流动连通的参考流动路径; 和（iv）连接区域（10），测试流动路径和参考流动路径彼此接触，接合区域通常包括允许液体向前流动的出口，导管，室或其它部分; 其中沿着参考流路流动的液体在到达接合区域时具有防止液体沿着测试流动路径的流动的效果。

9. 发明申请

WO2007110702A2 ASSAYS 审中-公开
公开(公告)号：WO2007110702A2
公开(公告)日：2007-10-04
申请号：PCT/IB2006004158
申请日：2006-11-22
申请人： INVERNESS MEDICAL SWITZERLAND , RAJ BALBIR
发明人： RAJ BALBIR
CPC分类号： G01N33/558 , G01N33/585 , G01N33/689 , G01N33/76
摘要： Provided are assays and devices to detect a target compound in urine.
摘要翻译：提供了用于检测尿中的目标化合物的测定和装置。

10. 发明申请

WO2005121800A3 IMPROVEMENTS IN OR RELATING TO LATERAL FLOW ASSAY DEVICES 审中-公开
标题翻译：改进或相关于侧流测试装置
公开(公告)号：WO2005121800A3
公开(公告)日：2006-02-16
申请号：PCT/GB2005002266
申请日：2005-06-08
申请人： INVERNESS MEDICAL SWITZERLAND , RAJ BALBIR
发明人： RAJ BALBIR
IPC分类号： G01N33/558
CPC分类号： G01N33/558 , Y10T29/49826
摘要： Disclosed is an assay device for determining the presence or absence of an analyte of interest in a sample, the device comprising a test strip, the test strip having a reading zone wherein the result of the test may be observed; the device further comprising a movable portion which is movable from a first ("testing") position to a second ("reading") position; wherein, at the first position the movable portion obscures the reading zone, and wherein movement of the movable portion from the first position to the second position uncovers or reveals the reading zone, rendering the reading zone available for visual inspection.
摘要翻译：公开了一种用于确定样品中感兴趣分析物的存在或不存在的测定装置，该装置包括测试条，测试条具有读数区，其中可以观察到测试结果; 该装置还包括可从第一（“测试”）位置移动到第二（“读取”）位置的可移动部分; 其中，在所述第一位置，所述可移动部分遮蔽所述读取区域，并且其中所述可移动部分从所述第一位置到所述第二位置的移动露出或露出所述读取区域，使得所述读取区域可用于目视检查。

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