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1. 发明申请

WO2012142397A2 MICROARRAY BASED SAMPLE DETECTION SYSTEM 审中-公开
标题翻译：基于微阵列样本检测系统
公开(公告)号：WO2012142397A2
公开(公告)日：2012-10-18
申请号：PCT/US2012/033498
申请日：2012-04-13
申请人： AKONNI BIOSYSTEMS, INC. , COONEY, Christopher, G. , QU, Peter, Qiang , PEROV, Alexander , PARKER, Jennifer
发明人： COONEY, Christopher, G. , QU, Peter, Qiang , PEROV, Alexander , PARKER, Jennifer
IPC分类号： G01N33/53 , G01N33/538
CPC分类号： C12Q1/6837 , B01J19/0046 , B01J2219/00385 , B01J2219/00576 , B01J2219/00644 , B01J2219/00722 , B01J2219/00725 , B01L3/502715 , B01L2200/026 , B01L2200/0684 , B01L2200/10 , B01L2300/0636 , B01L2300/0681 , B01L2300/069 , B01L2300/0816 , B01L2300/087 , B01L2300/0887 , B01L2300/161 , B01L2400/0406 , C12Q1/68 , G01N1/34 , G01N33/54386
摘要： A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using reliable films and methods for detecting microarray spots using an internal control fiuorophore in the array spot.
摘要翻译：公开了一种用于检测靶分子的微阵列组件。微阵列组件包括具有位于其中的微阵列的阵列室，其特征在于使阵列室内的液体移动。还公开了使用可靠的膜制备微阵列组件的方法和使用阵列斑点中的内部控制荧光团来检测微阵列斑点的方法。

2. 发明申请

WO2008064020A2 SYSTEM AND METHOD FOR PROVIDING MULTIPLE PARTICIPANTS WITH A CENTRAL ACCESS PORTAL TO GEOGRAPHIC POINT OF INTEREST 审中-公开
标题翻译：用于提供多个参与者的系统和方法，其具有访问地理学点的中央访问入口
公开(公告)号：WO2008064020A2
公开(公告)日：2008-05-29
申请号：PCT/US2007084584
申请日：2007-11-13
申请人： TELE ATLAS NORTH AMERICA INC , BECKER MARY R , SABBEY CRAIG PATRICK , UNDERCOFFLER JAY W , COHEN RICHARD , TEMMINK RIK , GOLDBERG DAVID , JONES MICHELLE , BROWN ROGER W , PARKER JENNIFER
发明人： BECKER MARY R , SABBEY CRAIG PATRICK , UNDERCOFFLER JAY W , COHEN RICHARD , TEMMINK RIK , GOLDBERG DAVID , JONES MICHELLE , BROWN ROGER W , PARKER JENNIFER
IPC分类号： G06F3/048 , G06F15/16
CPC分类号： G06Q30/00
摘要： A system and method of providing multiple participants with a centrally accessible content portal for geographic point of interest (POI) data, for subsequent use in creating map-based or spatial applications. Different entities can dynamically upload, update, retrieve, and use digital map and POI data. Additional features include the ability to handle the large amounts of POI data needed by multiple Application Developers, including data that is dynamic, or frequently changing; the ability to update POI attribute information and deliver it to the Application Developers; the ability to associate multiple points of entry (POE) with a POI, and to aggregate data from multiple Content Providers; and the use of a common geocoding engine and common digital map reference across all Content Providers, which ensures the consistency of the geocoding throughout all the POI data.
摘要翻译：一种向多个参与者提供地理兴趣点（POI）数据的集中可访问内容门户的系统和方法，用于随后用于创建基于地图或空间的应用。不同的实体可以动态地上传，更新，检索和使用数字地图和POI数据。其他功能还包括能够处理多个应用程序开发人员所需的大量POI数据，包括动态数据或频繁更改的数据; 更新POI属性信息并将其交付给应用程序开发人员的能力; 将多个入境点（POE）与POI相关联的能力，以及聚合来自多个内容提供者的数据的能力; 以及在所有内容提供商之间使用通用地理编码引擎和通用数字地图参考，从而确保所有POI数据中地理编码的一致性。

3. 发明申请

WO2017015636A1 INTEGRATED CONSUMABLE DATA MANAGEMENT SYSTEM & PLATFORM 审中-公开
标题翻译：综合消费数据管理系统与平台
公开(公告)号：WO2017015636A1
公开(公告)日：2017-01-26
申请号：PCT/US2016/043755
申请日：2016-07-22
申请人： MESO SCALE TECHNOLOGIES, LLC. , KOCHAR, Manish , BOSCO, Peter, J. , CHAMBERLIN, Ian, D. , JEFFREY-COKER, Bandele , JONES, Eric, M. , KRIVOY, Gary, I. , KRUEGER, Don, E. , LEIMKUEHLER, Aaron, H. , WU, Pei-Ming , NGUYEN, Kim-Xuan , OBEROI, Pankaj , PANG, Louis, W. , PARKER, Jennifer , PELLICIER, Victor , SAMMONS, Nick , SIGAL, George , WOHLSTADTER, Jacob , VOCK, Mike , SMITH, Stanley, T. , STEVENS, Carl, C. , OSBORNE, Roger, D. , PAGE, Kenneth , WADE, Michael, T. , WILLOUGHBY, Jon , WANG, Lei
发明人： KOCHAR, Manish , BOSCO, Peter, J. , CHAMBERLIN, Ian, D. , JEFFREY-COKER, Bandele , JONES, Eric, M. , KRIVOY, Gary, I. , KRUEGER, Don, E. , LEIMKUEHLER, Aaron, H. , WU, Pei-Ming , NGUYEN, Kim-Xuan , OBEROI, Pankaj , PANG, Louis, W. , PARKER, Jennifer , PELLICIER, Victor , SAMMONS, Nick , SIGAL, George , WOHLSTADTER, Jacob , VOCK, Mike , SMITH, Stanley, T. , STEVENS, Carl, C. , OSBORNE, Roger, D. , PAGE, Kenneth , WADE, Michael, T. , WILLOUGHBY, Jon , WANG, Lei
IPC分类号： G01N33/53 , G01N33/543 , G06F17/30 , C40B60/12
CPC分类号： G06Q10/10 , G06F19/00 , G06Q10/087 , G16H10/40
摘要： The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.
摘要翻译：本发明涉及将消耗品数据与生物测定中使用的测定消耗品相关联的方法，装置和系统。提供了测定系统和相关的消耗品，其中测定系统基于该消耗品特有的消耗性数据来调整测定方案的一个或多个步骤。描述了各种类型的消耗品数据，以及在通过测定系统进行测定时使用这些数据的方法。本发明还涉及用于进行自动生物测定的消耗品（例如，试剂盒和试剂容器），软件，可部署数据的捆，计算机可读介质，装载车，仪器，系统和方法。

4. 发明申请

WO2012142397A3 MICROARRAY BASED SAMPLE DETECTION SYSTEM 审中-公开
标题翻译：基于微阵列样本检测系统
公开(公告)号：WO2012142397A3
公开(公告)日：2013-01-17
申请号：PCT/US2012033498
申请日：2012-04-13
申请人： AKONNI BIOSYSTEMS INC , COONEY CHRISTOPHER G , QU PETER QIANG , PEROV ALEXANDER , PARKER JENNIFER
发明人： COONEY CHRISTOPHER G , QU PETER QIANG , PEROV ALEXANDER , PARKER JENNIFER
IPC分类号： G01N33/53 , G01N33/538
CPC分类号： C12Q1/6837 , B01J19/0046 , B01J2219/00385 , B01J2219/00576 , B01J2219/00644 , B01J2219/00722 , B01J2219/00725 , B01L3/502715 , B01L2200/026 , B01L2200/0684 , B01L2200/10 , B01L2300/0636 , B01L2300/0681 , B01L2300/069 , B01L2300/0816 , B01L2300/087 , B01L2300/0887 , B01L2300/161 , B01L2400/0406 , C12Q1/68 , G01N1/34 , G01N33/54386
摘要： A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using reliable films and methods for detecting microarray spots using an internal control fiuorophore in the array spot.
摘要翻译：公开了一种用于检测靶分子的微阵列组件。微阵列组件包括具有位于其中的微阵列的阵列室，其特征在于使阵列室内的液体移动。还公开了使用可靠的膜制备微阵列组件的方法和使用阵列斑点中的内部控制荧光团来检测微阵列斑点的方法。

5. 发明申请

WO2023022845A2 GRAM-NEGATIVE BACTERIA CONTAINING PEPTIDE SECRETION SYSTEM 审中-公开
公开(公告)号：WO2023022845A2
公开(公告)日：2023-02-23
申请号：PCT/US2022/038064
申请日：2022-07-22
申请人： BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM , COLE, Timothy Jeffrey , PARKER, Jennifer , TELFORD, Mady
发明人： DAVIES, Bryan , KIM, Sun-Young
IPC分类号： C07K14/195 , C12N1/20 , C12N15/62 , C12Q1/68 , A61K35/74 , C12N15/70 , C12N15/74
摘要： Gram-negative bacterial cells for expression and secretion of heterologous peptides are disclosed. The bacterial cells include a first nucleic acid encoding a secretion signal sequence, e.g., a microcin secretion signal sequence, fused to a heterologous peptide, a second nucleic acid encoding a C39 peptidase-containing ATP-binding cassette transporter (PCAT), and a third nucleic acid encoding a membrane fusion protein. The gram-negative bacterial cells secrete the heterologous peptide from the bacterial cytosol to an external environment outside of the bacterial outer membrane. Methods for preparation and delivery of peptides to external environments are also described.

6. 发明申请

WO2018017156A1 INTEGRATED CONSUMABLE DATA MANAGEMENT SYSTEM & PLATFORM 审中-公开
标题翻译：集成的可消费数据管理系统和平台
公开(公告)号：WO2018017156A1
公开(公告)日：2018-01-25
申请号：PCT/US2017/014360
申请日：2017-01-20
申请人： MESO SCALE TECHNOLOGIES, LLC. , KOCHAR, Manish , BOSCO, Peter J. , CHAMBERLIN, Ian D. , JEFFREY-COKER, Bandele , JONES, Eric M. , KRIVOY, Gary I. , KRUEGER, Don E. , LEIMKUEHLER, Aaron H. , WU, Pei-Ming , NGUYEN, Kim-xuan , OBEROI, Pankaj , PANG, Louis W. , PARKER, Jennifer , PELLICIER, Victor , SAMMONS, Nick , SIGAL, George , WOHLSTADTER, Jacob , VOCK, Mike , SMITH, Stanley T , STEVENS, Carl C. , OSBORNE, Roger D. , PAGE, Kenneth , WADE, Michael T. , WILLOUGHBY, Jon , WANG, Lei
发明人： KOCHAR, Manish , BOSCO, Peter J. , CHAMBERLIN, Ian D. , JEFFREY-COKER, Bandele , JONES, Eric M. , KRIVOY, Gary I. , KRUEGER, Don E. , LEIMKUEHLER, Aaron H. , WU, Pei-Ming , NGUYEN, Kim-xuan , OBEROI, Pankaj , PANG, Louis W. , PARKER, Jennifer , PELLICIER, Victor , SAMMONS, Nick , SIGAL, George , WOHLSTADTER, Jacob , VOCK, Mike , SMITH, Stanley T , STEVENS, Carl C. , OSBORNE, Roger D. , PAGE, Kenneth , WADE, Michael T. , WILLOUGHBY, Jon , WANG, Lei
IPC分类号： C40B60/04 , G01N35/02 , G06K19/08
CPC分类号： G06Q10/10 , B01L3/50853 , B01L9/523 , B01L2200/143 , B01L2300/021 , G01N35/0099 , G01N35/028 , G01N2035/00356 , G01N2035/103 , G06Q10/087 , G16H10/40
摘要： The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay-systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.
摘要翻译：本发明涉及用于将消耗性数据与生物测定中使用的测定消耗品相关联的方法，装置和系统。提供化验系统和相关联的消耗品，其中化验系统基于特定于该消耗品的消耗性数据来调整化验协议的一个或多个步骤。描述了各种类型的消耗性数据，以及在通过测定系统进行测定时使用这些数据的方法。本发明还涉及用于执行自动生物测定的消耗品（例如，试剂盒和试剂容器），软件，数据可展开包，计算机可读介质，装载车，仪器，系统和方法。

7. 发明申请

WO2008100420A1 PROVIDING NETWORK-BASED ACCESS TO PERSONALIZED USER INFORMATION 审中-公开
标题翻译：提供基于网络的访问个人化用户信息
公开(公告)号：WO2008100420A1
公开(公告)日：2008-08-21
申请号：PCT/US2008/001677
申请日：2008-02-08
申请人： MCCONNELL, Christopher, F. , MCCONNELL, Claire , LOFTUS, Kevin , PARKER, Jennifer, W.
发明人： MCCONNELL, Christopher, F. , MCCONNELL, Claire , LOFTUS, Kevin , PARKER, Jennifer, W.
IPC分类号： H04M3/42
CPC分类号： H04M3/4938 , H04M3/42059 , H04M7/006 , H04M2201/39 , H04M2201/40
摘要： An apparatus and method for providing network-based access to personalized user content. The apparatus may include a memory that is publicly-accessible via a communications network. The memory may store configuration information that is customized by a user and that defines personalized content of the user. The apparatus may further include an interface module in communication with the memory. The interface module may also be publicly-accessible via the communications network and may include a processor configured to access the configuration information to determine the personalized content to be provided to a remote user device associated with the user. The processor may further be configured to establish a communications connection with the remote user device via the communications network, access the personalized content, and provide, in an audio form, at least a portion of the personalized content to the remote user device via the communications network.
摘要翻译：一种用于向个性化用户内容提供基于网络的访问的装置和方法。该装置可以包括经由通信网络可公开访问的存储器。存储器可以存储由用户定制并且定义用户的个性化内容的配置信息。该装置还可以包括与存储器通信的接口模块。接口模块还可以经由通信网络可公开访问，并且可以包括被配置为访问配置信息以确定要提供给与用户相关联的远程用户设备的个性化内容的处理器。处理器还可以被配置为经由通信网络建立与远程用户设备的通信连接，访问个性化内容，并且通过通信以音频形式向远程用户设备提供至少一部分个性化内容网络。

8. 发明申请

WO2008064020A3 SYSTEM AND METHOD FOR PROVIDING MULTIPLE PARTICIPANTS WITH A CENTRAL ACCESS PORTAL TO GEOGRAPHIC POINT OF INTEREST 审中-公开
公开(公告)号：WO2008064020A3
公开(公告)日：2008-05-29
申请号：PCT/US2007/084584
申请日：2007-11-13
申请人： TELE ATLAS NORTH AMERICA, INC. , BECKER, Mary R. , SABBEY, Craig Patrick , UNDERCOFFLER, Jay W. , COHEN, Richard , TEMMINK, Rik , GOLDBERG, David , JONES, Michelle , BROWN, Roger W. , PARKER, Jennifer
发明人： BECKER, Mary R. , SABBEY, Craig Patrick , UNDERCOFFLER, Jay W. , COHEN, Richard , TEMMINK, Rik , GOLDBERG, David , JONES, Michelle , BROWN, Roger W. , PARKER, Jennifer
IPC分类号： G06F15/16
摘要： A system and method of providing multiple participants with a centrally accessible content portal for geographic point of interest (POI) data, for subsequent use in creating map-based or spatial applications. Different entities can dynamically upload, update, retrieve, and use digital map and POI data. Additional features include the ability to handle the large amounts of POI data needed by multiple Application Developers, including data that is dynamic, or frequently changing; the ability to update POI attribute information and deliver it to the Application Developers; the ability to associate multiple points of entry (POE) with a POI, and to aggregate data from multiple Content Providers; and the use of a common geocoding engine and common digital map reference across all Content Providers, which ensures the consistency of the geocoding throughout all the POI data.

9. 发明申请

WO2004032353A1 A SYSTEM AND METHOD FOR WIRELESS AUDIO COMMUNICATION WITH A COMPUTER 审中-公开
标题翻译：一种用于与计算机进行无线音频通信的系统和方法
公开(公告)号：WO2004032353A1
公开(公告)日：2004-04-15
申请号：PCT/US2003/031193
申请日：2003-10-01
申请人： MCCONNELL, Christopher, Frank , PLEATMAN, Thomas, Alan , PARKER, Jennifer, Ware , BILLMYER, Chad, Walter
发明人： MCCONNELL, Christopher, Frank , PLEATMAN, Thomas, Alan , PARKER, Jennifer, Ware , BILLMYER, Chad, Walter
IPC分类号： H04B1/38
CPC分类号： H04M1/21 , G06F3/16 , G10L15/26 , H04M3/4938 , H04M2201/40 , H04M2201/60
摘要： A method and system for interacting with a computer is provided. In one embodiment, a communications connection between the computer and a communications device is established. An audio signal from the user is received and processed to determine a desired function. A determination is made as to whether the desired function requires a spoken response and, if so, a spoken response to the user is provided by way of the remote communications device and the desired function is performed. In an alternate embodiment, an entry in a data file is read and a communications connection initiated between the computer and a remote communications device responsive to the entry. An audio notification is generated according to the entry and transmitted by way of the remote communications device.
摘要翻译：提供了一种与计算机交互的方法和系统。在一个实施例中，建立计算机和通信设备之间的通信连接。来自用户的音频信号被接收和处理以确定期望的功能。确定所需功能是否需要口语响应，如果是，则通过远程通信设备提供对用户的口头响应，并且执行期望的功能。在替代实施例中，读取数据文件中的条目，并且响应于条目在计算机和远程通信设备之间发起通信连接。根据条目生成音频通知，并通过远程通信设备进行发送。

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