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1. 发明申请

WO2004033455A2 SUCCINATE SALTS OF HETEROCYCLIC DPP-IV INHIBITORS 审中-公开
标题翻译：杂环DPP-IV抑制剂的琥珀酸盐
公开(公告)号：WO2004033455A2
公开(公告)日：2004-04-22
申请号：PCT/DK2003/000668
申请日：2003-10-08
申请人： NOVO NORDISK A/S , RASMUSSEN, Kaare, Gyberg , JENSEN, Anette, Frost , NYGAARD, Lars
发明人： RASMUSSEN, Kaare, Gyberg , JENSEN, Anette, Frost , NYGAARD, Lars
IPC分类号： C07D473/06
CPC分类号： C07D473/06 , C07D473/04 , C07D473/08
摘要： The present invention relates to therapeutically active and selective hemisuccinate salts of inhibitors of the enzyme DPP-IV of formula (I), pharmaceutical compositions comprising the salts and the use of such salts for and the manufacture of medicaments for treating diseases that are associated with proteins that are subject to inactivation by DPP-IV, such as type 2 diabetes and obesity.
摘要翻译：本发明涉及式（I）的酶DPP-IV的抑制剂的治疗活性和选择性半琥珀酸盐，包含所述盐的药物组合物和所述盐用于和制造药物的用途用于治疗与通过DPP-IV失活的蛋白质相关的疾病，例如2型糖尿病和肥胖症。

2. 发明申请

WO0039578A3 METHOD AND APPARATUS FOR ESTIMATION OF A CELL COUNT IN A BODY FLUID 审中-公开
标题翻译：估计体液中细胞数量的方法和装置
公开(公告)号：WO0039578A3
公开(公告)日：2000-11-09
申请号：PCT/DK9900725
申请日：1999-12-21
申请人： FOSS ELECTRIC AS , RIDDER CARSTEN , NYGAARD LARS
发明人： RIDDER CARSTEN , NYGAARD LARS
IPC分类号： G01N21/35 , G01N33/04 , A01J5/013
CPC分类号： G01N21/35
摘要： A method for estimating the cell count in a body fluid such as milk, by recording a MID-IR spectrum, analysing the data representing the spectral information in the recorded spectrum by use of multivariate chemometric methods for deriving properties and/or concentrations from spectral information, such as Partial Least Squares Regression (PLS-R), Multiple Linear Regression (MLR), Principle Component Regression (PCR) or Artificial Neural Networks (ANN), and deriving information on the number of cells in the body fluid from the recorded spectrum. The advantage is that the MID-IR spectrum is often measured and registered for milk samples, and an estimate of the cell count may obtained from the already registered data. Preferably measurements of conductivity, temperature, and yield are included, in order to improve the reliability of an estimate concerning the probability of a possible attack of mastitis.
摘要翻译：通过记录MID-IR光谱，通过使用多变量化学计量方法分析表示记录光谱中的光谱信息的数据以从光谱信息中导出性质和/或浓度，来估计诸如牛奶的体液中的细胞计数的方法，诸如偏最小二乘回归（PLS-R），多重线性回归（MLR），主成分回归（PCR）或人工神经网络（ANN），并且从记录的频谱导出关于体液中细胞数目的信息。其优点是经常测量和记录中红外光谱的牛奶样品，并且可以从已经登记的数据中获得细胞计数的估计值。优选包括电导率，温度和产量的测量，以提高关于乳腺炎可能发作的可能性的估计的可靠性。

3. 发明申请

WO2007082545A1 DRY STICK DEVICE AND METHOD FOR DETERMINING AN ANALYTE IN A SAMPLE 审中-公开
标题翻译：干燥装置和用于确定样品中分析物的方法
公开(公告)号：WO2007082545A1
公开(公告)日：2007-07-26
申请号：PCT/DK2007/050005
申请日：2007-01-19
申请人： Lattec I/S , NYGAARD, Lars
发明人： NYGAARD, Lars
IPC分类号： G01N33/52 , G01N33/558 , G01N33/62
CPC分类号： G01N33/525 , Y10T436/142222 , Y10T436/143333 , Y10T436/144444 , Y10T436/171538 , Y10T436/200833 , Y10T436/201666 , Y10T436/202499 , Y10T436/21
摘要： The present invention relates to a dry stick test device for the determination of an analyte in a sample by means of a chemical assay. The device comprises: (i) optionally a solid support, (ii) at least one reagent pad comprising a reagent capable of reacting with the analyte, a derivative of said analyte or an indicator compound for said analyte to provide a detectable signal when in moistened state, and (iii) a development pad which is located in contact with the at least one reagent pad, optionally between the solid support and the at least one reagent pad, said development pad comprises at least one controlling compound capable of providing a condition required for the reagent to react with the analyte to provide a detectable signal, wherein the at least one reagent pad and the development pad are arranged to avoid precipitation of sample component(s) on the top-face of the device.
摘要翻译：本发明涉及一种用于通过化学测定法测定样品中分析物的干棒测试装置。该装置包括：（i）任选的固体支持物，（ii）至少一个试剂垫，其包含能够与分析物反应的试剂，所述分析物的衍生物或所述分析物的指示剂化合物，以在被润湿时提供可检测的信号状态，和（iii）与所述至少一个试剂垫接触定位的显影垫，任选地位于所述固体支持体和所述至少一个试剂垫之间，所述显影垫包括至少一种能够提供所需条件的控制化合物用于使试剂与分析物反应以提供可检测的信号，其中所述至少一个试剂垫和显影垫被布置成避免样品组分沉淀在所述装置的顶面上。

4. 发明申请

WO1993019364A1 A METHOD FOR DETERMINING UREA IN MILK 审中-公开
标题翻译：一种用于测定牛奶中尿素的方法
公开(公告)号：WO1993019364A1
公开(公告)日：1993-09-30
申请号：PCT/DK1993000111
申请日：1993-03-25
申请人： A/S FOSS ELECTRIC , NYGAARD, Lars , LAPP, Torben , ARNVIDARSON, Börkur
发明人： A/S FOSS ELECTRIC
IPC分类号： G01N33/04
CPC分类号： G01N33/04 , G01N21/3577 , G01N2201/129 , Y10S250/91
摘要： A method for determining, with an accuracy better than 0.007 %, expressed as Standard Error of Prediction, the concentration of urea in a concentration range of 0-0.1 % in a milk sample containing at least 1 % fat, at least 1 % dissolved lactose, and at least 1 % protein, by an infrared absorption measuring technique, comprising: (a) determining absorption in an infrared radiation waveband from 1000 cm-1 (10.0 um) to 4000 cm-1 (2.50 um) of the milk sample, wherein at least one determination is made in a waveband from 1000 cm-1 (10.0 um) to 1800 cm-1 (5.56 um), in which urea absorbs, at least one determination being made in a waveband in which fat absorbs, at least one determination being made in a waveband where lactose absorbs, and at least one determination being made in a waveband where protein absorbs; (b) determining, on the basis of the absorption determinations and predetermined parameters established by multivariate calibration, a contribution from fat, lactose, and protein in the waveband where urea absorbs, and (c) quantitatively assessing the concentration of urea in the sample on the basis of the absorption in the waveband where urea absorbs and on the basis of the determined contribution from fat, lactose, and protein in the waveband.

5. 发明申请

WO2012163531A8 DEVICE FOR REFINING OF SILICON BY DIRECTIONAL SOLIDIFICATION IN AN OXYGEN-CONTAINING ATMOSPHERE AS WELL AS A REFINING METHOD OF SILICON 审中-公开
标题翻译：用于通过在含氧大气中的方向固化来精炼硅的装置，作为硅的精制方法
公开(公告)号：WO2012163531A8
公开(公告)日：2013-06-27
申请号：PCT/EP2012002308
申请日：2012-05-31
申请人： EVONIK SOLAR NORGE AS , NYGAARD LARS , SOERVIK ARVID INGE , BRYNJAR SYLTEN , KVANDE RANNVEIG , HUGO FRANZ
发明人： NYGAARD LARS , SOERVIK ARVID INGE , BRYNJAR SYLTEN , KVANDE RANNVEIG , HUGO FRANZ
IPC分类号： C30B11/00 , B22D27/04 , C01B33/037 , C30B29/06 , C30B35/00 , H01L31/18
CPC分类号： C30B11/00 , C01B33/037 , C30B11/003 , C30B29/06 , C30B35/005 , H01L31/182 , Y02E10/546 , Y02P70/521
摘要： There is provided a device for a directional solidification process in particular of liquid silicon to produce solar grade silicon as well as the refining method for directional solidification. The device comprises a furnace with heating elements that tolerate an oxygen-containing atmosphere and are arranged above a bottom plate, wherein on the bottom plate a crucible/mould with liquid silicon is placed on. In addition, there are provided a method of the directional solidification, a computer readable medium on which computer software is stored on and a program element for the operation of the device for directional solidification.
摘要翻译：提供了用于定向凝固方法的装置，特别是用于制造太阳能级硅的液态硅的定向凝固方法以及用于定向凝固的精炼方法。该装置包括具有耐受含氧气氛并且设置在底板上方的加热元件的炉，其中在底板上放置有具有液态硅的坩埚/模具。此外，提供了定向凝固的方法，其上存储计算机软件的计算机可读介质和用于定向凝固的装置的操作的程序元件。

6. 发明申请

WO1996034606A1 PHARMACEUTICAL COMPOSITION CONTAINING TIAGABINE HYDROCHLORIDE AND THE PROCESS FOR ITS PREPARATION 审中-公开
标题翻译：含有盐酸氢氯化物的药物组合物及其制备方法
公开(公告)号：WO1996034606A1
公开(公告)日：1996-11-07
申请号：PCT/DK1996000192
申请日：1996-04-29
申请人： NOVO NORDISK A/S , SVENSSON, Jorgen, Ryhl , NYGAARD, Lars , ANDERSEN, Tina, Meinertz , WEIBEL, Helle , HJORTH, Thyge, Borup
发明人： NOVO NORDISK A/S
IPC分类号： A61K31/445
CPC分类号： A61K31/4535 , A61K9/2013 , A61K47/22
摘要： The present invention provides a new stable pharmaceutical composition containing tiagabine hydrochloride as active ingredient.
摘要翻译：本发明提供了含有盐酸噻加滨作为活性成分的新的稳定的药物组合物。

7. 发明申请

WO2012163534A1 STARTING MATERIALS FOR PRODUCTION OF SOLAR GRADE SILICON FEEDSTOCK 审中-公开
标题翻译：开始生产太阳能硅胶进料的材料
公开(公告)号：WO2012163534A1
公开(公告)日：2012-12-06
申请号：PCT/EP2012/002311
申请日：2012-05-31
申请人： EVONIK SOLAR NORGE AS , NYGAARD, Lars , ANDRESEN, Birger , CHRISTIANSEN, Stein
发明人： NYGAARD, Lars , ANDRESEN, Birger , CHRISTIANSEN, Stein
IPC分类号： C01B31/36 , C01B33/025
CPC分类号： C01B33/025 , C01B32/956
摘要： There is provided a method of providing a first and a second starting material for a carbothermic reduction process, comprising the steps of: a) preparing a quartz product containing 0.5 ppm (w/w) or less boron and 1 ppm (w/w) or less phosphorus from natural quartz; b) providing part of said quartz product as the first starting material; c) reacting part of the quartz product with a carbon material, such as carbon black, containing 0.5 ppm (w/w) or less boron and 0.4 ppm (w/w) or less phosphorus to produce a silicon carbide product containing 1.5 ppm (w/w) or less, boron and 3.0 ppm (w/w) or less phosphorus; d) providing said silicon carbide product as the second starting material. A agglomerated composition comprising the quartz product and the silicon carbide product is also provided.
摘要翻译：提供了一种提供用于碳热还原法的第一和第二原料的方法，包括以下步骤：a）制备含有0.5ppm（w / w）或更少的硼和1ppm（w / w）的石英产物，或更少的天然石英磷; b）提供所述石英产品的一部分作为第一起始材料; c）使石英产物的一部分与含有0.5ppm（w / w）或更少的硼和0.4ppm（w / w）或更少的磷的碳材料，例如炭黑反应，以产生含有1.5ppm（ w / w）以下，硼和3.0ppm（w / w）以下的磷; d）提供所述碳化硅产物作为第二起始材料。还提供了包含石英产品和碳化硅产品的聚集组合物。

8. 发明申请

WO2012163531A1 DEVICE FOR REFINING OF SILICON BY DIRECTIONAL SOLIDIFICATION IN AN OXYGEN-CONTAINING ATMOSPHERE AS WELL AS A REFINING METHOD OF SILICON 审中-公开
标题翻译：用于通过在含氧大气中的方向固化来精炼硅的装置，作为硅的精制方法
公开(公告)号：WO2012163531A1
公开(公告)日：2012-12-06
申请号：PCT/EP2012/002308
申请日：2012-05-31
申请人： EVONIK SOLAR NORGE AS , NYGAARD, Lars , SØRVIK, Arvid, Inge , BRYNJAR, Sylten , KVANDE, Rannveig
发明人： NYGAARD, Lars , SØRVIK, Arvid, Inge , BRYNJAR, Sylten , KVANDE, Rannveig
IPC分类号： C30B11/00 , C30B29/06 , C01B33/037 , H01L31/18 , C30B35/00 , B22D27/04
CPC分类号： C30B11/00 , C01B33/037 , C30B11/003 , C30B29/06 , C30B35/005 , H01L31/182 , Y02E10/546 , Y02P70/521
摘要： There is provided a device for a directional solidification process in particular of liquid silicon to produce solar grade silicon as well as the refining method for directional solidification. The device comprises a furnace with heating elements that tolerate an oxygen-containing atmosphere and are arranged above a bottom plate, wherein on the bottom plate a crucible/mould with liquid silicon is placed on. In addition, there are provided a method of the directional solidification, a computer readable medium on which computer software is stored on and a program element for the operation of the device for directional solidification.
摘要翻译：提供了用于定向凝固方法的装置，特别是用于制造太阳能级硅的液态硅的定向凝固方法以及用于定向凝固的精炼方法。该装置包括具有耐受含氧气氛并且设置在底板上方的加热元件的炉，其中在底板上放置有具有液态硅的坩埚/模具。此外，提供了定向凝固的方法，其上存储计算机软件的计算机可读介质和用于定向凝固的装置的操作的程序元件。

9. 发明申请

WO2012163530A1 COMPONENTS OF PLANT, SUCH AS REDUCTION FURNACE BODY AND/OR ELECTRODE, IN PARTICULAR FOR A REDUCTION FURNACE 审中-公开
标题翻译：植物的组分，如还原炉体和/或电极，特别是用于还原炉
公开(公告)号：WO2012163530A1
公开(公告)日：2012-12-06
申请号：PCT/EP2012/002307
申请日：2012-05-31
申请人： EVONIK SOLAR NORGE AS , NYGAARD, Lars , ANDRESEN, Birger , SØRVIK, Arvid, Inge
发明人： NYGAARD, Lars , ANDRESEN, Birger , SØRVIK, Arvid, Inge
IPC分类号： C01B33/00 , C01B33/025 , C04B35/565 , C04B35/65 , F27D1/16 , C22B5/06
CPC分类号： C01B33/025 , C04B35/573 , C04B35/634 , C04B35/66 , C04B2235/48 , C04B2235/72 , C04B2235/727 , F27B14/06 , F27B14/14 , F27D11/08 , F27D11/12 , F27D99/0006
摘要： Component of a plant for the production of silicon, in particular liquid silicon and solar grade silicon, wherein the component is a reduction furnace body and/or an electrode that comprise a composition selected from (i) 80-95 % (w/w) of a silicon carbide product containing 1.5 ppm (w/w) or less boron and 3.0 ppm (w/w) or less phosphorus; (ii) 5-20 % (w/w) of a silicon product containing 1.5 ppm (w/w) or less boron and 3.0 ppm (w/w) or less phosphorus; and (iii) 0.1-5 % (w/w) of a binding agent, such as a resin, e.g. a synthetic resin; and, wherein the sum of this composition is 100 % (w/w) before a curing process, a process for the production as well as the use of the silicon containing material.
摘要翻译：用于生产硅，特别是液体硅和太阳能级硅的设备的组件，其中所述组分是还原炉体和/或电极，其包含选自（i）80-95％（w / w）的含有1.5ppm（w / w）或更低的硼和3.0ppm（w / w）或更少的磷的碳化硅产品; （ii）5-20％（w / w）含有1.5ppm（w / w）或更低的硼和3.0ppm（w / w）或更少的磷的硅产物; 和（iii）0.1-5％（w / w）的粘合剂，例如树脂，例如。合成树脂; 并且其中该组合物的总和在固化过程之前为100％（w / w），制备方法以及含硅材料的使用。

10. 发明申请

WO2004033455A3 HEMISUCCINATE SALTS OF HETEROCYCLIC DPP-IV INHIBITORS 审中-公开
标题翻译：异丙酚DPP-IV抑制剂的HEMISUCCINATE销售
公开(公告)号：WO2004033455A3
公开(公告)日：2004-05-27
申请号：PCT/DK0300668
申请日：2003-10-08
申请人： NOVO NORDISK AS , RASMUSSEN KAARE GYBERG , JENSEN ANETTE FROST , NYGAARD LARS
发明人： RASMUSSEN KAARE GYBERG , JENSEN ANETTE FROST , NYGAARD LARS
IPC分类号： C07D473/04 , C07D473/06 , C07D473/08 , A61K31/522
CPC分类号： C07D473/06 , C07D473/04 , C07D473/08
摘要： The present invention relates to therapeutically active and selective hemisuccinate salts of inhibitors of the enzyme DPP-IV of formula (I), pharmaceutical compositions comprising the salts and the use of such salts for and the manufacture of medicaments for treating diseases that are associated with proteins that are subject to inactivation by DPP-IV, such as type 2 diabetes and obesity.
摘要翻译：本发明涉及式（I）酶DPP-IV的抑制剂的治疗活性和选择性半琥珀酸盐，包含该盐的药物组合物和用于治疗与蛋白质相关的疾病的药物的这种盐的用途和用途其受DPP-IV的失活，例如2型糖尿病和肥胖症。

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