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1. 发明申请

WO1994002627A1 RECOMBINANT ANTIBODY AGAINST HUMAN INTERLEUKIN-1 审中-公开
标题翻译：对人类白细胞介素-1的重组抗体
公开(公告)号：WO1994002627A1
公开(公告)日：1994-02-03
申请号：PCT/JP1993000941
申请日：1993-07-08
申请人： OTSUKA PHARMACEUTICAL CO., LTD. , HIRAI, Yoshikatsu , OWENS, Raymond, John , OMOTO, Yasukazu , NISHIDA, Tsutomu
发明人： OTSUKA PHARMACEUTICAL CO., LTD.
IPC分类号： C12P21/08
CPC分类号： C07K16/245 , A61K38/00 , C07K2319/00
摘要： A chimeric antibody against human IL-1, and other human-mouse chimeric and reshaped antibodies, wherein the L chain has the constant region of human antibody molecules and the variable region of mouse antihuman IL-1 antibody molecules having the amino acid sequence described in the sequence identification no. 1 and the H chain has the constant region of human antibody molecules and the variable region of mouse antihuman IL-1 antibody molecules having the amino acid sequence described in the sequence identification no. 2. This antibody is utilizable in treating various diseases accompanied by the abnormal production of IL-1 and conducting diagnostic imaging of IL-1 producing sites in the body.
摘要翻译：针对人IL-1的嵌合抗体和其他人 - 小鼠嵌合和重整抗体，其中L链具有人抗体分子的恒定区和具有下述氨基酸序列的小鼠抗人IL-1抗体分子的可变区序列识别号 1，并且H链具有人抗体分子的恒定区和具有序列鉴定编号中所述的氨基酸序列的小鼠抗人IL-1抗体分子的可变区。 2.该抗体可用于治疗伴随IL-1异常产生的各种疾病，并进行体内IL-1产生部位的诊断成像。

2. 发明申请

WO2013018446A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS 审中-公开
标题翻译：电子感光元件，工艺盒和电子照相设备
公开(公告)号：WO2013018446A1
公开(公告)日：2013-02-07
申请号：PCT/JP2012/065440
申请日：2012-06-11
申请人： CANON KABUSHIKI KAISHA , TANAKA, Daisuke , SUGIYAMA, Kazumichi , NISHIDA, Tsutomu
发明人： TANAKA, Daisuke , SUGIYAMA, Kazumichi , NISHIDA, Tsutomu
IPC分类号： G03G5/05 , G03G5/047 , G03G5/147
CPC分类号： G03G15/751 , G03G5/051 , G03G5/0514 , G03G5/0517 , G03G5/056 , G03G5/0564 , G03G5/0578 , G03G5/14752 , G03G5/14756 , G03G5/14786 , G03G5/14791 , G03G2215/00957
摘要： The electrophotographic photosensitive member includes a surface layer containing (α) a polycarbonate or polyester resin not having a siloxane structure at the end, (β) a polycarbonate or polyester or acrylic resin having a siloxane structure at the end, and (γ) a methyl benzoate, an ethyl benzoate, a benzyl acetate, ethyl 3-ethoxypropionate or a diethylene glycol ethyl methyl ether.
摘要翻译：电子照相感光构件包括表面层，其包含（a）末端不具有硅氧烷结构的聚碳酸酯或聚酯树脂，（ß）末端具有硅氧烷结构的聚碳酸酯或聚酯或丙烯酸树脂，和（α）甲基苯甲酸酯，苯甲酸乙酯，乙酸苄酯，3-乙氧基丙酸乙酯或二甘醇乙基甲基醚。

3. 发明申请

WO2011071093A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS 审中-公开
标题翻译：电子照相感光元件，工艺盒和电子照相设备
公开(公告)号：WO2011071093A1
公开(公告)日：2011-06-16
申请号：PCT/JP2010/072069
申请日：2010-12-02
申请人： CANON KABUSHIKI KAISHA , OKUDA, Atsushi , NISHIDA, Tsutomu
发明人： OKUDA, Atsushi , NISHIDA, Tsutomu
IPC分类号： G03G5/05
CPC分类号： G03G5/0564 , G03G5/056 , G03G5/0578
摘要： The present invention provides an electrophotographic photosensitive member, and a process cartridge and an electrophotographic apparatus, each of which has the electrophotographic photosensitive member. In the electrophotographic photosensitive member, a charge transport layer used as a surface layer contains a charge transport material, a polycarbonate resin A which has a specific amount of a specific repeating structural unit of a specific siloxane moiety, and a polyester resin C and/or a polycarbonate resin D, each of which has a specific repeating structural unit. In the charge transport layer, a matrix-domain structure is formed in which a matrix is formed from the charge transport material and the polyester resin C and/or the polycarbonate resin D, and domains are formed in the above matrix from the polycarbonate resin A.
摘要翻译：本发明提供了一种电子照相感光构件，以及具有电照相感光构件的处理盒和电子照相设备。在电子照相感光构件中，用作表面层的电荷输送层包含电荷输送材料，具有特定硅氧烷部分的特定重复结构单元的特定量的聚碳酸酯树脂A和聚酯树脂C和/或聚碳酸酯树脂D，其具有特定的重复结构单元。在电荷输送层中，形成矩阵结构，其中由电荷输送材料和聚酯树脂C和/或聚碳酸酯树脂D形成基质，并且从聚碳酸酯树脂A在上述基质中形成畴。

4. 发明申请

WO1983002776A1 SUBSTANCE NAMED OA-7653 审中-公开
标题翻译：物质名称OA-7653
公开(公告)号：WO1983002776A1
公开(公告)日：1983-08-18
申请号：PCT/JP1980000041
申请日：1980-03-08
申请人： NISHIDA, Tsutomu , SUGAWARA, Michiharu , KAMOGASHIRA, Takashi
IPC分类号： C07G11/00
CPC分类号： C12R1/55 , C12P1/06
摘要： This antibiotic substance, yielded by a novel strain belonging to Streptomyces hygroscopicus, exhibits antibacterial action against various bacteria and is useful as an effective ingredient in an antibacterial agent.
摘要翻译：由属于吸水链霉菌属的新菌株产生的这种抗生素物质对各种细菌表现出抗菌作用，并且可用作抗菌剂中的有效成分。

5. 发明申请

WO2012070663A1 PROCESS FOR FORMING UNEVEN STRUCTURE ON SURFACE OF SURFACE LAYER OF CYLINDRICAL ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND PROCESS FOR PRODUCING CYLINDRICAL ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER HAVING UNEVEN STRUCTURE FORMED ON SURFACE OF SURFACE LAYER OF SAME 审中-公开
标题翻译：用于形成圆柱形电致感光构件表面表面的未结构的方法，以及生产具有在SU表面形成的未结构的圆柱形电子显微成像的方法
公开(公告)号：WO2012070663A1
公开(公告)日：2012-05-31
申请号：PCT/JP2011/077269
申请日：2011-11-18
申请人： CANON KABUSHIKI KAISHA , KAWAI, Yasuhiro , UEMATSU, Hiroki , OGAKI, Harunobu , TAKAHASHI, Koji , NISHIDA, Tsutomu
发明人： KAWAI, Yasuhiro , UEMATSU, Hiroki , OGAKI, Harunobu , TAKAHASHI, Koji , NISHIDA, Tsutomu
IPC分类号： G03G5/00
CPC分类号： B29C59/021 , G03G5/147 , G03G5/14704 , G03G5/14708 , G03G5/14713 , G03G5/14726 , G03G5/14756 , G03G5/14795
摘要： In the case where an uneven structure is formed on the surface of cylindrical electrophotographic photosensitive members, for the purpose of reducing the variation of the uneven structure between the individual cylindrical electrophotographic photosensitive members even when a large number of cylindrical electrophotographic photosensitive members are continuously processed, an insert is inserted into the interior of a cylindrical electrophotographic photosensitive member including a cylindrical substrate and a surface layer, the surface uneven structure of a molding member is transferred to and formed on the surface of the surface layer of the photosensitive member. The insert includes an abutting part having an outer peripheral surface capable of abutting on the inner peripheral surface of the substrate, a connecting part positioned inside of the abutting part in the radical direction and a shaft part positioned inside of the connecting part in the radical direction.
摘要翻译：在圆柱形电子照相感光构件的表面上形成不均匀结构的情况下，为了减少各个圆柱形电子照相感光构件之间的不均匀结构的变化，即使当大量圆柱形电子照相感光构件被连续处理时，将插入件插入到包括圆柱形基底和表面层的圆柱形电子照相感光构件的内部中，将模制构件的表面不均匀结构转移到感光构件的表面层的表面上并形成在感光构件的表面层上。插入件包括具有能够抵接在基板的内周面上的外周面的抵接部，沿自由度方向位于抵接部的内侧的连接部和沿自由度方向位于连接部的内侧的轴部。

6. 发明申请

WO2010035882A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS 审中-公开
标题翻译：电子照相感光元件，工艺盒和电子照相设备
公开(公告)号：WO2010035882A1
公开(公告)日：2010-04-01
申请号：PCT/JP2009/067121
申请日：2009-09-24
申请人： CANON KABUSHIKI KAISHA , OKUDA, Atsushi , UESUGI, Hirotoshi , NOGUCHI, Kazunori , NISHIDA, Tsutomu
发明人： OKUDA, Atsushi , UESUGI, Hirotoshi , NOGUCHI, Kazunori , NISHIDA, Tsutomu
IPC分类号： G03G5/147 , G03G5/047 , G03G5/05 , G03G21/10
CPC分类号： G03G5/0578 , G03G5/0564 , G03G5/14756 , G03G5/14773 , G03G15/751 , G03G21/0011
摘要： An electrophotographic photosensitive member having a surface layer which contains a silicon-containing compound in an amount of less than 0.6% by mass based on the whole solid content in the surface layer, where the silicon-containing compound in the surface layer has a siloxane moiety in an amount of 0.01% by mass or more, based on the whole solid content in the surface layer, and its surface has specific depressions. Also disclosed are a process cartridge and an electrophotographic apparatus which have the electrophotographic photosensitive member.
摘要翻译：一种具有表面层的电子照相感光构件，其表面层中含硅化合物具有硅氧烷部分的表面层中的全部固体含量小于0.6质量％的含硅化合物基于表面层中的整体固体含量为0.01质量％以上，并且其表面具有特定的凹陷。还公开了具有电子照相感光构件的处理盒和电子照相设备。

7. 发明申请

WO1992002236A1 AGENT FOR PREVENTING AND TREATING HEPATITIS 审中-公开
标题翻译：用于预防和治疗乙型肝炎的药剂
公开(公告)号：WO1992002236A1
公开(公告)日：1992-02-20
申请号：PCT/JP1991001067
申请日：1991-08-09
申请人： OTSUKA PHARMACEUTICAL CO., LTD. , NAKAI, Satoru , AKAMATSU, Seiji , MASUI, Yoshihiro , NISHIDA, Tsutomu , KAMOGASHIRA, Takashi , HIRAI, Yoshikatu
发明人： OTSUKA PHARMACEUTICAL CO., LTD.
IPC分类号： A61K37/02
CPC分类号： C07K14/545 , A61K38/00
摘要： An agent for preventing and treating hepatitis, containing at least one member selected among interleukin-1 and its derivatives as the active ingredient, which significantly inhibits the blood GOT and GPT activities as a marker for the onset of hepatitis and also suppresses the presentation of jaundice.

8. 发明申请

WO2013018450A1 METHOD FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER 审中-公开
标题翻译：生产电子光敏成员的方法
公开(公告)号：WO2013018450A1
公开(公告)日：2013-02-07
申请号：PCT/JP2012/065673
申请日：2012-06-13
申请人： CANON KABUSHIKI KAISHA , SUGIYAMA, Kazumichi , TANAKA, Daisuke , NISHIDA, Tsutomu
发明人： SUGIYAMA, Kazumichi , TANAKA, Daisuke , NISHIDA, Tsutomu
IPC分类号： G03G5/05 , G03G5/047 , G03G5/147
CPC分类号： G03G5/14752 , G03G5/0514 , G03G5/0517 , G03G5/0525 , G03G5/056 , G03G5/0564 , G03G5/0578 , G03G5/0589 , G03G5/0592 , G03G5/078 , G03G5/14756 , G03G5/14786 , G03G5/14791
摘要： The present invention provides a method for producing an electrophotographic photosensitive member, wherein a surface-layer coating solution includes (α) a polycarbonate or polyester resin not having a siloxane moiety at the end, (β) a polycarbonate or polyester or acrylate resin having a siloxane moiety at the end,(γ) toluene or xylene as a solvent, and (δ) a compound, for example, a methyl benzoate, an ethyl benzoate, a benzyl acetate, ethyl 3-ethoxypropionate or a diethylene glycol ethyl methyl ether.
摘要翻译：本发明提供了一种电子照相感光构件的制造方法，其中表面层涂布液包括：（a）末端不具有硅氧烷部分的聚碳酸酯或聚酯树脂，（ß）聚碳酸酯或聚酯或丙烯酸酯树脂，其具有末端的硅氧烷部分，（α）甲苯或二甲苯作为溶剂，和（d）化合物，例如苯甲酸甲酯，苯甲酸乙酯，乙酸苄酯，3-乙氧基丙酸乙酯或二甘醇乙基甲基醚。

9. 发明申请

WO2012165642A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS 审中-公开
标题翻译：电子照相感光元件，工艺盒和电子照相设备
公开(公告)号：WO2012165642A1
公开(公告)日：2012-12-06
申请号：PCT/JP2012/064339
申请日：2012-05-28
申请人： CANON KABUSHIKI KAISHA , TAKAHASHI, Koji , UEMATSU, Hiroki , MITSUI, Takahiro , KAWAI, Yasuhiro , NISHIDA, Tsutomu , OGAWA, Hideki
发明人： TAKAHASHI, Koji , UEMATSU, Hiroki , MITSUI, Takahiro , KAWAI, Yasuhiro , NISHIDA, Tsutomu , OGAWA, Hideki
IPC分类号： G03G5/147 , G03G21/00
CPC分类号： G03G15/75 , G03G5/0592 , G03G5/0596 , G03G5/147 , G03G5/14795
摘要： An electrophotographic photosensitive member in which image deletion is hardly produced, and a process cartridge and electrophotographic apparatus having the electrophotographic photosensitive member are provided. For this, a surface of the electrophotographic photosensitive member includes a plurality of depressed portions and a portion other than the depressed portions, each of the depressed portions having a depth of 0.5 to 5 μm and an opening longest diameter of 20 to 80 μm; when a 500 μm × 500 μm square region is disposed in an arbitrary position of the surface of the electrophotographic photosensitive member, the area of the depressed portions in the 500 μm × 500 μm square region is from 10000 to 90000 μm 2 , and the area of a flat part contained in the portion other than the depressed portions is from 80000 to 240000 μm 2 .
摘要翻译：设置几乎不产生图像删除的电子照相感光构件，以及具有电子照相感光构件的处理盒和电子照相设备。为此，电子照相感光构件的表面包括多个凹陷部分和凹陷部分以外的部分，每个凹陷部分的深度为0.5至5μm，开口最长直径为20至80μm; 当在电子照相感光构件的表面的任意位置设置500μm×500μm的正方形区域时，500μm×500μm的正方形区域的凹部的面积为10000〜90000μm2，包含在凹陷部以外的部分的平坦部分为80000〜240000μm2。

10. 发明申请

WO1996012017A1 GENE PARTICIPATING IN APOPTOSIS 审中-公开
标题翻译：基因参与疫苗
公开(公告)号：WO1996012017A1
公开(公告)日：1996-04-25
申请号：PCT/JP1995002090
申请日：1995-10-12
申请人： OTSUKA PHARMACEUTICAL CO., LTD. , AUSTRALIAN NATIONAL UNIVERSITY , SHINDO, Yutaka , NISHIDA, Tsutomu , ADACHI, Masakazu , NAORA, Hiroto , NAORA, Honami
发明人： OTSUKA PHARMACEUTICAL CO., LTD. , AUSTRALIAN NATIONAL UNIVERSITY
IPC分类号： C12N15/12
CPC分类号： C07K14/4747 , A61K38/00
摘要： A gene participating in apoptosis characterized by containing a base sequence coding for the amino acid sequence represented by SEQ ID NO:1. The gene can be used for the expression and detection of proteins participating in apoptosis and is useful for the diagnosis and clarification of the pathological conditions of various diseases wherein apoptosis participates and for the prevention and treatment of apoptosis-related diseases by inducing or inhibiting apoptosis.
摘要翻译：参与凋亡的基因，其特征在于含有编码SEQ ID NO：1所示的氨基酸序列的碱基序列。该基因可用于参与凋亡的蛋白质的表达和检测，并且可用于诊断和澄清其中凋亡参与并通过诱导或抑制凋亡来预防和治疗凋亡相关疾病的各种疾病的病理状况。

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