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1. 发明申请

WO2004110540A1 METHOD AND APPARATUS FOR MONITORING BARIATRIC PARAMETERS AND SLEEP DISORDERED BREATHING 审中-公开
标题翻译：监测巴比特参数和睡眠障碍性呼吸的方法和装置
公开(公告)号：WO2004110540A1
公开(公告)日：2004-12-23
申请号：PCT/AU2004/000796
申请日：2004-06-18
申请人： RESMED LIMITED , HEBBLEWHITE, Malcolm, Ronald , GALLAHUE, Kieran , MULCAHY, David , SURJADI, Hary, Soesanto , GOELDI, Benriah , PHUAH, Chee, Keong , RICHARD, Ron , STEWART, Dierdre
发明人： HEBBLEWHITE, Malcolm, Ronald , GALLAHUE, Kieran , MULCAHY, David , SURJADI, Hary, Soesanto , GOELDI, Benriah , PHUAH, Chee, Keong , RICHARD, Ron , STEWART, Dierdre
IPC分类号： A61M16/00
CPC分类号： A61B5/08 , A61B5/4818 , A61M16/021 , A61M2205/52 , A61M2230/00 , G06F19/00
摘要： A method and system is disclosed for monitoring SDB managment that compares titrated CPAP pressure against BMI and AHI/AI indices. The method comprises the steps of storing data on a computer, where the data is collected over a time period of interest. The data consists of BMI and one or more of AHI, AI, Usage and CPAP titration measurements. The method further comprises illustrating the stored data for a selected time period.
摘要翻译：公开了一种用于监测SDB管理的方法和系统，其将滴定的CPAP压力与BMI和AHI / AI指数进行比较。该方法包括以下步骤：在计算机上存储数据，其中在感兴趣的时间段内收集数据。数据由BMI和AHI，AI，使用和CPAP滴定测量中的一种或多种组成。该方法还包括说明所选择的时间段内存储的数据。

2. 发明申请

WO9903821A3 PROCESS FOR ISOMERISATION OF TILIDINE 审中-公开
标题翻译：酪氨酸异构化方法
公开(公告)号：WO9903821A3
公开(公告)日：1999-05-20
申请号：PCT/IE9800052
申请日：1998-06-26
申请人： RUSSINSKY LTD , NIKOLOPOULOS ANGELO , SCHICKANEDER HELMUT , MULCAHY DAVID
发明人： NIKOLOPOULOS ANGELO , SCHICKANEDER HELMUT , MULCAHY DAVID
IPC分类号： C07C227/36 , C07C229/48
CPC分类号： C07C227/36 , C07B2200/07 , C07C2601/16 , C07C229/48
摘要： Cis/trans Tilidine base with an enhanced content of the trans isomer is prepared by mixing a substantially pure cis Tilidine base with water under acidic conditions, preferably using phosphoric acid, at pH values between 2 to 6. Alternatively the substantially pure cis Tilidine base is mixed with a solvent, especially diisopropylethylamine or dimethylformamide under basic conditions at pH values of from 8 to 14. The reaction mixtures thus formed are heated to yield isomerised cis/trans Tilidine base with an enhanced content of the trans isomer.
摘要翻译：通过在酸性条件下，优选使用磷酸，在2至6的pH值下，将基本上纯的顺式替利陆碱与水混合来制备具有增强的反式异构体含量的顺式/反式替利陆碱。或者，基本上纯的顺式替赖啶碱是在碱性条件下在8至14的pH值下与溶剂，特别是二异丙基乙胺或二甲基甲酰胺混合。将由此形成的反应混合物加热，得到具有增强的反式异构体含量的异构化顺式/反式替利啶碱。

3. 发明申请

WO2008028248A1 METHOD AND APPARATUS FOR TREATING APNEA/HYPOPNEA 审中-公开
标题翻译：用于处理APNEA / HYPOPNEA的方法和装置
公开(公告)号：WO2008028248A1
公开(公告)日：2008-03-13
申请号：PCT/AU2007/001326
申请日：2007-09-06
申请人： RESMED LTD , RICHARD, Ron , FARRUGIA, Steven, Paul , KWOK, Philip, Rodney , MULCAHY, David
发明人： RICHARD, Ron , FARRUGIA, Steven, Paul , KWOK, Philip, Rodney , MULCAHY, David
IPC分类号： A61M16/00
CPC分类号： A61M16/0051 , A61B5/0826 , A61B5/4836 , A61M16/00 , A61M16/0057 , A61M16/0069 , A61M16/024 , A61M2016/0027
摘要： Methods and/or apparatuses for treating sleep-disordered breathing (SDB) are provided. In particular, systems and/or methods are provided which may temporarily boost the pressure of a supply of breathable gas provided by an AutoSet device for the treatment of hypopnea (S30). In certain example embodiments, a supply of breathable is provided to patients to treat apneas and/or hypopneas. The presence and/or absence of apneas and/or hypopneas are detected (e.g. by monitoring the Apnea-Hypopnea Index) (S32, S34). When hypopnea events are detected, the pressure of the supply of breathable gas temporarily is increased above the Pcrit and/or CPAP levels, at least during patient inspiration (S36). When the hypopnea events are normalized (S38), the pressure is reduced. In certain example embodiments, the pressure will not be increased when a non-hypopnea event is detected at the same time as a hypopnea event.
摘要翻译：提供了治疗睡眠呼吸障碍（SDB）的方法和/或装置。特别地，提供了可以临时提高由AutoSet装置提供的用于治疗呼吸不足的可呼吸气体供应的压力的系统和/或方法（S30）。在某些示例性实施例中，向患者提供透气剂供应以治疗呼吸暂停和/或呼吸不足。检测到呼吸暂停和/或呼吸不足的存在和/或不存在（例如通过监测呼吸暂停 - 呼吸不足指数）（S32，S34）。当检测到呼吸不足事件时，临时提供透气气体的压力至少在患者吸气期间增加至高于Pcrit和/或CPAP水平（S36）。当呼吸不足事件被归一化时（S38），压力降低。在某些示例性实施例中，当在与呼吸不良事件同时检测到非呼吸不足事件时，压力不会增加。

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