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    • 7. 发明申请
    • FLOORING AND EDGING MEMBER FOR USE THEREIN
    • 地板和加工用户使用
    • WO1993006319A1
    • 1993-04-01
    • PCT/GB1992001729
    • 1992-09-17
    • MORGAN, Philip, Nigel
    • E04F19/04
    • E04H5/10E04F19/045E04F19/0463E04F2019/0431
    • A floor edging member (1) has an elongate wall portion (4) extending between one edge portion engageable with a floor surface and another edge portion engageable with an upright wall surface and connector means at the inner face of the wall portion (4) for connection with locating means for locating the wall portion (4) in use. Alternatively the edge portions are not engageable but are spaced from their respective surfaces. A flooring system comprising such an edge portion is also described though the edge member can be used on existing floors. The edging member (1) can be used as a buffer or protector for the lower regions of walls to reduce damage for example in industrial and commercial situations by trolleys or other vehicles yet maintain a hygienic, easily cleaned transition between the floor and a wall. It is particularly useful in cold storage rooms where walls are traditionally made of easily deformed insulating material and a hygienic environment is important.
    • 地板边缘构件(1)具有在与地板表面接合的一个边缘部分之间延伸的细长壁部分(4)和可与直立壁表面接合的另一边缘部分和在壁部分(4)的内表面处的连接装置, 与在使用中定位壁部分(4)的定位装置的连接。 或者,边缘部分不可接合,但是它们各自的表面间隔开。 还描述了包括这种边缘部分的地板系统,尽管边缘构件可以用在现有的地板上。 边缘构件(1)可以用作壁的下部区域的缓冲器或保护器,以例如在工业和商业情况下通过手推车或其他车辆减少损坏,同时保持地板和墙壁之间的卫生,容易清洁的过渡。 它在冷藏室特别有用,其中传统的墙壁由容易变形的绝缘材料制成,卫生环境很重要。
    • 9. 发明申请
    • THERAPEUTIC AMINE-ARYLSULFONAMIDE CONJUGATE COMPOUNDS
    • 治疗性胺 - 芳基磺酰胺缀合物化合物
    • WO2007079470A2
    • 2007-07-12
    • PCT/US2007060033
    • 2007-01-03
    • ALGEBRA INCMORGAN PHILIP FREDERICKKELLEY JAMES LEROY
    • MORGAN PHILIP FREDERICKKELLEY JAMES LEROY
    • A61K31/551A61K31/34A61K31/343A61K31/381A61K31/496A61K31/5513C07D405/02C07D409/02C07D487/04
    • C07D307/14A61K47/55C07D413/12
    • Therapeutic amine-arylsulfonamide conjugate compounds, of the general formula (I) wherein R' is [D-W-], hydroxyl, or alkoxyl; R" is independently [D-W-], hydrogen, alkoxy, alkyl, cycloalkyl, alkenyl, alkynyl or aryl, or R" and R" together with the nitrogen atom to which they are attached form a 4-, 5-, 6-, 7- or 8-membered ring optionally containing one or two further heteroatoms independently selected from nitrogen, oxygen and sulfur; D is independently a therapeutic amine radical comprising at least one nitrogen atom and optionally at least one oxygen atom coupled to W or W' by a nitrogen or oxygen atom; W and W' are a chemical bond or linker; wherein cither R' is [D-W-] or at least one R" is [D-W-], and pharmaceutically acceptable esters, amides, salts or solvates thereof, pharmaceutical compositions containing same, methods for their preparation, and their use in treating psychiatric, neurologic and metabolic disorders are disclosed.
    • 其中R'为[D-W-],羟基或烷氧基的通式(I)的治疗性胺 - 芳基磺酰胺缀合物化合物; R“独立地为[DW-],氢,烷氧基,烷基,环烷基,烯基,炔基或芳基,或者R”和R“与它们所连接的氮原子一起形成4-,5-,6-, 7-或8-元环,其任选地含有一个或两个独立地选自氮,氧和硫的另外的杂原子; D独立地为治疗性胺基,其包含至少一个氮原子和任选地至少一个与W或W'连接的氧原子 氮或氧原子; W和W'为化学键或连接基;其中R'为[DW-]或至少一个R“为[DW-],及其药学上可接受的酯,酰胺,盐或溶剂化物, 公开了含有其的药物组合物,其制备方法以及它们在治疗精神病,神经病和代谢疾病中的用途。