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1. 发明申请

WO2016005819A2 MULTI-CELL TRANSDUCER 审中-公开
标题翻译：多单元传感器
公开(公告)号：WO2016005819A2
公开(公告)日：2016-01-14
申请号：PCT/IB2015/001724
申请日：2015-07-10
申请人： MICROTECH MEDICAL TECHNOLOGIES LTD.
发明人： SAVOIA, Alessandro, Stuart , CALIANO, Giosuè , MELAMUD, Alexander , TAMMAM, Eric, S.
CPC分类号： H01L41/0825 , B06B1/0622 , H01L41/25
摘要： The present invention relates to a transducer device having a planar array of electroacoustic cells, each including a piezoelectric bilayer unit. The transducer device achieves high transmission sensitivity across a broad bandwidth. The transducer device may be designed to have a broad or a focused directivity pattern, or may be multi-frequency, depending on the particular application and has a range of applications. For example, the transducer device may be used with an implanted passive ultrasonically excitable resonating sensor, to excite the sensor and/or to interrogate the sensor, for example in conjunction with Doppler-based analysis of the resonance frequency of the sensor, and/or to locate an implanted sensor. The invention also relates to a method of manufacturing the device.
摘要翻译：本发明涉及具有电声单元的平面阵列的换能器装置，每个包括压电双层单元。传感器器件在宽带宽下实现高传输灵敏度。换能器装置可以被设计为具有宽的或聚焦的指向性图案，或者可以是多频的，这取决于具体应用并且具有一系列的应用。例如，传感器装置可以与植入的被动超声波可激发谐振传感器一起使用，以激励传感器和/或询问传感器，例如结合基于对传感器的共振频率的基于多普勒的分析，和/或定位植入的传感器。本发明还涉及一种制造该装置的方法。

2. 发明申请

WO2014140684A9 IMPLANTABLE ANCHOR 审中-公开
标题翻译：可植入锚
公开(公告)号：WO2014140684A9
公开(公告)日：2014-11-27
申请号：PCT/IB2013003046
申请日：2013-07-03
申请人： MICROTECH MEDICAL TECHNOLOGIES LTD
发明人： TAMMAM ERIC S , WEIZMAN OLEG , DLUGACH YEKATERINA , AGIAN NADAV
IPC分类号： A61B5/00 , A61B5/0215 , A61B5/03 , A61B5/20 , A61M5/00
CPC分类号： A61B5/6882 , A61B5/0215 , A61B5/036 , A61B5/145 , A61B5/14503 , A61B5/20 , A61B5/4244 , A61B5/686 , A61B5/6869 , A61B5/6876 , A61B5/6885 , A61B2560/063 , A61B2560/066 , A61B2562/12 , B21D31/00
摘要： The device and method of the invention generally relate to a system and method for percutaneous delivery, implantation and securement of an anchor at a target site. The system comprises an anchor having a bridge, a first stabilizer having a crimped state and a deployed state, a second stabilizer having a crimped state and a deployed state, and a positioning arm. The system may further comprise a cannula, pushrod, and sheath. The system permits the deposit of an anchor at a target location in the body by utilizing a controlled amount of force. The anchors and methods are particularly well-suited to implantation within the body of a living animal or human to monitor various physiological conditions.
摘要翻译：本发明的装置和方法通常涉及一种用于经皮递送，植入和固定锚点在目标部位的系统和方法。该系统包括具有桥的锚固件，具有卷曲状态的第一稳定器和展开状态，具有卷曲状态和展开状态的第二稳定器以及定位臂。系统还可以包括插管，推杆和护套。该系统允许通过利用受控量的力将锚固体沉积在身体的目标位置。锚和方法特别适合于植入活的动物或人的体内以监测各种生理状况。

3. 发明申请

WO2019207358A2 METHODS FOR THE USE OF INHERENT FREQUENCY SHIFTING MECHANISMS FOR SENSORS RESPONSE READING WITH CONTINUOUS WAVE EXCITATION 审中-公开
公开(公告)号：WO2019207358A2
公开(公告)日：2019-10-31
申请号：PCT/IB2019/000496
申请日：2019-04-19
申请人： MICROTECH MEDICAL TECHNOLOGIES LTD.
发明人： KOHEN, Amir , BECKER, Yuval , TAMMAM, Eric S.
摘要： A method and system of the invention generally relate to measuring ambient pressure in systems comprising incompressible fluids. Particularly, the method and system relate to monitoring pressure within body lumens. The ambient pressure may be measured by transmitting a frequency comb having non-uniform spacing between transmitted frequencies at the passive sensor and measuring the frequency response of the passive sensor. In one embodiment, a higher-order harmonic of the sensor is excited and measured to determine the ambient pressure. In another embodiment, the frequency response of frequencies in-between the transmitted frequencies are measured to determine the ambient pressure.

4. 发明申请

WO2014177936A2 IMPLANTABLE DEVICE WITH BRIDGE 审中-公开
标题翻译：具有桥梁的可植入装置
公开(公告)号：WO2014177936A2
公开(公告)日：2014-11-06
申请号：PCT/IB2014/001565
申请日：2014-03-14
申请人： MICROTECH MEDICAL TECHNOLOGIES LTD.
发明人： DLUGACH, Yekaterina , AGIAN, Nadav
CPC分类号： A61B5/686 , A61B5/0215 , A61B5/6876 , A61B2090/3966 , A61F2/915 , A61F2002/91541 , A61F2002/91575 , A61F2250/0039 , A61F2250/0096 , Y10T29/49826 , Y10T29/49908
摘要： This invention relates to an implantable device for a physiologic sensor, comprising an implantable expandable anchor, a bridge on which the sensor is secured, as well as an optional adapting ring. The invention also relates to a method of monitoring bodily functions using the anchor and sensor. The anchor is compressed and the bridge assumes an elongated shape during delivery to a target lumen. Upon deployment at the target site, the anchor expands and the bridge bows into the interior lumen of the expanded anchor, distancing the sensor from the vessel wall. This invention also relates to a method of manufacturing said device and a method of implanting a sensor.
摘要翻译：本发明涉及一种用于生理传感器的可植入装置，包括可植入的可扩张锚，传感器固定在其上的桥以及可选的适配环。本发明还涉及使用锚和传感器监测身体功能的方法。锚固体被压缩并且桥梁在递送到目标管腔期间呈现细长形状。在目标地点部署时，锚杆膨胀，桥梁弯曲成扩展锚固件的内腔，将传感器与血管壁隔开。本发明还涉及制造所述装置的方法和植入传感器的方法。

5. 发明申请

WO2020104846A1 SYSTEM AND METHOD FOR DEPLOYMENT OF AN IMPLANTABLE DEVICE HAVING AN ATTACHMENT ELEMENT AND METHODS OF MONITORING PHYSIOLOGICAL DATA USING MULTIPLE SENSOR DEVICES 审中-公开
公开(公告)号：WO2020104846A1
公开(公告)日：2020-05-28
申请号：PCT/IB2019/001240
申请日：2019-11-18
申请人： MICROTECH MEDICAL TECHNOLOGIES LTD.
发明人： ARTHUR, Amir , SHARON, Nadav , KOHEN, Amir , HAREL, Amir , JANAI, Erez
IPC分类号： A61B5/0215 , A61B5/00 , A61B17/34 , A61M37/00 , A61N1/372
摘要： Systems and methods for deployment and implantation of an implantable device having an attachment element directly in a luminal wall or tissue to monitor or detect physiological conditions. In an embodiment of the invention, a device is positioned at one or more target locations in the body to enable a medical professional to obtain physiological information for the target site(s). The invention also provides novel methods of monitoring physiological conditions using multiple sensors via techniques such as ultrasound with frequency separation or spatial separation.

6. 发明申请

WO2019243896A3 APPARATUS AND SYSTEM FOR INCREASING OBJECT VISIBILITY 审中-公开
公开(公告)号：WO2019243896A3
公开(公告)日：2019-12-26
申请号：PCT/IB2019/000796
申请日：2019-06-19
申请人： MICROTECH MEDICAL TECHNOLOGIES, LTD.
发明人： KOHEN, Amir
IPC分类号： A61B8/08 , A61B34/20 , G01H13/00
摘要： The invention provides an apparatus, system, and method employing a marker based on a membrane that is reflective of ultrasonic waves. The technique allows controlling the resonance frequency of the membrane, amplitude, non-linearity and reverberation period by modifying material properties and geometrical properties (membrane area and thickness) such that the marker appears prominently on ultrasound imaging. The marker can be tailored for use either in color Doppler mode or harmonics mode.

7. 发明申请

WO2019243896A2 APPARATUS, SYSTEM, AND METHOD FOR INCREASING OBJECT VISIBILITY 审中-公开
公开(公告)号：WO2019243896A2
公开(公告)日：2019-12-26
申请号：PCT/IB2019/000796
申请日：2019-06-19
申请人： MICROTECH MEDICAL TECHNOLOGIES, LTD.
发明人： KOHEN, Amir
摘要： The invention provides an apparatus, system, and method employing a marker based on a membrane that is reflective of ultrasonic waves. The technique allows controlling the resonance frequency of the membrane, amplitude, non-linearity and reverberation period by modifying material properties and geometrical properties (membrane area and thickness) such that the marker appears prominently on ultrasound imaging. The marker can be tailored for use either in color Doppler mode or harmonics mode.

8. 发明申请

WO2019207358A3 METHODS FOR THE USE OF INHERENT FREQUENCY SHIFTING MECHANISMS FOR SENSORS RESPONSE READING WITH CONTINUOUS WAVE EXCITATION 审中-公开
公开(公告)号：WO2019207358A3
公开(公告)日：2019-10-31
申请号：PCT/IB2019/000496
申请日：2019-04-19
申请人： MICROTECH MEDICAL TECHNOLOGIES LTD.
发明人： KOHEN, Amir , BECKER, Yuval , TAMMAM, Eric S.
IPC分类号： A61B5/0215 , A61B5/03 , G01H13/00 , G01L9/00 , G01N29/036 , A61B8/04 , A61B90/00
摘要： A method and system of the invention generally relate to measuring ambient pressure in systems comprising incompressible fluids. Particularly, the method and system relate to monitoring pressure within body lumens. The ambient pressure may be measured by transmitting a frequency comb having non-uniform spacing between transmitted frequencies at the passive sensor (100) and measuring the frequency response of the passive sensor. In one embodiment, a higher-order harmonic of the sensor is excited and measured to determine the ambient pressure. In another embodiment, the frequency response of frequencies in-between the transmitted frequencies are measured to determine the ambient pressure.

9. 发明申请

WO2014177936A3 IMPLANTABLE DEVICE WITH BRIDGE 审中-公开
标题翻译：具有桥梁的可植入装置
公开(公告)号：WO2014177936A3
公开(公告)日：2015-03-05
申请号：PCT/IB2014001565
申请日：2014-03-14
申请人： MICROTECH MEDICAL TECHNOLOGIES LTD
发明人： DLUGACH YEKATERINA , AGIAN NADAV
IPC分类号： A61B5/00 , A61F2/915
CPC分类号： A61B5/686 , A61B5/0215 , A61B5/6876 , A61B2090/3966 , A61F2/915 , A61F2002/91541 , A61F2002/91575 , A61F2250/0039 , A61F2250/0096 , Y10T29/49826 , Y10T29/49908
摘要： This invention relates to an implantable device for a physiologic sensor, comprising an implantable expandable anchor, a bridge on which the sensor is secured, as well as an optional adapting ring. The invention also relates to a method of monitoring bodily functions using the anchor and sensor. The anchor is compressed and the bridge assumes an elongated shape during delivery to a target lumen. Upon deployment at the target site, the anchor expands and the bridge bows into the interior lumen of the expanded anchor, distancing the sensor from the vessel wall. This invention also relates to a method of manufacturing said device and a method of implanting a sensor.
摘要翻译：本发明涉及一种用于生理传感器的可植入装置，包括可植入的可扩张锚，传感器固定在其上的桥以及可选的适配环。本发明还涉及使用锚和传感器监测身体功能的方法。锚固体被压缩并且桥梁在递送到目标管腔期间呈现细长形状。在目标地点部署时，锚杆膨胀，桥梁弯曲成扩展锚固件的内腔，将传感器与血管壁隔开。本发明还涉及制造所述装置的方法和植入传感器的方法。

10. 发明申请

WO2016005819A3 MULTI-CELL TRANSDUCER 审中-公开
标题翻译：多细胞传感器
公开(公告)号：WO2016005819A3
公开(公告)日：2016-03-10
申请号：PCT/IB2015001724
申请日：2015-07-10
申请人： MICROTECH MEDICAL TECHNOLOGIES LTD
发明人： SAVOIA ALESSANDRO STUART , CALIANO GIOSUÈ , MELAMUD ALEXANDER , TAMMAM ERIC S
IPC分类号： B06B1/06
CPC分类号： H01L41/0825 , B06B1/0622 , H01L41/25
摘要： The present invention relates to a transducer device having a planar array of electroacoustic cells, each including a piezoelectric bilayer unit. The transducer device achieves high transmission sensitivity across a broad bandwidth. The transducer device may be designed to have a broad or a focused directivity pattern, or may be multi-frequency, depending on the particular application and has a range of applications. For example, the transducer device may be used with an implanted passive ultrasonically excitable resonating sensor, to excite the sensor and/or to interrogate the sensor, for example in conjunction with Doppler-based analysis of the resonance frequency of the sensor, and/or to locate an implanted sensor. The invention also relates to a method of manufacturing the device.
摘要翻译：本发明涉及一种具有平面阵列的电声单元的换能器装置，每个单元包括一个压电双层单元。换能器装置在宽带宽内实现了高传输灵敏度。换能器装置可以被设计成具有宽的或聚焦的方向性图案，或者可以是多频率的，这取决于特定的应用并且具有一定范围的应用。例如，换能器装置可以与植入的无源超声可激励的谐振传感器一起使用，以例如结合传感器的谐振频率的基于多普勒的分析来激发传感器和/或询问传感器，和/或找到植入的传感器。本发明还涉及制造该装置的方法。

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